Semaglutide utilization associated with reduced ninety-day postoperative complications following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Varthi A, Rubio D, Grauer J. Semaglutide utilization associated with reduced ninety-day postoperative complications following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024 PMID: 39491749, DOI: 10.1016/j.spinee.2024.10.011.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsAdverse eventsPostoperative complicationsT2DM patientsCurrent Procedural TerminologyElixhauser Comorbidity IndexED visitsLumbar fusionHospital readmissionEmergency departmentOdds of postoperative complicationsNinety-day postoperative complicationsImpact of semaglutideOdds of hospital readmissionMonths of surgeryRetrospective cohort studyPostoperative adverse eventsMinor adverse eventsType II diabetes mellitusRisk of type I errorDiagnosis of T2DMII diabetes mellitusYears of ageP116. National trends and risk factors for new-onset depression following posterior lumbar fusion
Day W, Gouzoulis M, Zhu J, Seddio A, Fourman M, Grauer J. P116. National trends and risk factors for new-onset depression following posterior lumbar fusion. The Spine Journal 2024, 24: s119. DOI: 10.1016/j.spinee.2024.06.138.Peer-Reviewed Original ResearchNew-onset depressionPosterior lumbar fusionNational administrative claims databaseSingle-level posterior lumbar fusionRisk factorsDevelopment of new-onset depressionAdministrative claims databasePostoperative complicationsLumbar fusionNational trendsFactors associated with patientsClaims databaseAggregate patient dataAdult patientsTarget risk mitigation strategiesMultivariate logistic regressionPsychiatric risk factorsPotential risk factorsElixhauser Comorbidity IndexPercentage of patientsHigher oddsCase-controlAlcohol/drug abuseDiagnosis of tumorsLogistic regression100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Zhu J, Rubio D, Grauer J. 100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024, 24: s52-s53. DOI: 10.1016/j.spinee.2024.06.543.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsImpact of semaglutideHospital readmissionPostoperative outcomesElixhauser Comorbidity IndexED visitsT2DM patientsCurrent Procedural TerminologyEmergency departmentLumbar fusionAdverse eventsOdds of hospital readmissionOutcome measures IncidenceRisk of type I errorInferior postoperative outcomesDiagnosis of T2DMMonths of surgeryYear of surgeryRetrospective cohort studyMinor adverse eventsType II diabetes mellitusMatched 1:4Management of diabetesRate and risk factors for inpatient falls following single-level posterior lumbar fusion: A national registry study
Gouzoulis M, Jabbouri S, Seddio A, Moran J, Day W, Ratnasamy P, Grauer J. Rate and risk factors for inpatient falls following single-level posterior lumbar fusion: A national registry study. North American Spine Society Journal (NASSJ) 2024, 20: 100549. PMID: 39318705, PMCID: PMC11417567, DOI: 10.1016/j.xnsj.2024.100549.Peer-Reviewed Original ResearchPosterior lumbar fusionSingle-level posterior lumbar fusionInpatient fallsOdds ratioLumbar fusionFall prevention programsIncidence of secondary injuryNational sample of patientsRisk factorsDecreased odds ratioPatient variablesPotential patient outcomesMultivariate logistic regressionNational registry studySample of patientsPrevention programsInpatient costsMedicaid insuranceActive deliriumAlcohol use disorderMethods Adult patientsSpinal pathologyOutcome metricsCommercial insuranceNational sample