Shangqin Guo, PhD

Associate Professor in Cell Biology

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Appointments

Cell Biology

Primary

Contact Info

shangqin.guo@yale.edu

203.737.6411

Cell Biology

10 Amistad St.

New Haven, CT 06520-8005

United States

About

Titles

Associate Professor in Cell Biology

Appointments

Cell Biology
Associate Professor Tenure
Primary
Cell Biology

Education & Training

PhD: Boston University (2005)

Research

Overview

Medical Research Interests

Cell Biology; Cellular Reprogramming; Hematopoietic Stem Cells; Leukemia, Experimental

ORCID
0000-0003-1157-0423
Guo lab
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Research at a Glance

Yale Co-Authors

Frequent collaborators of Shangqin Guo's published research.

Jun Lu, PhD
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View 13 Common Publications
Cynthia M. Megyola
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View 5 Common Publications
Diane Krause, MD, PhD
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View 4 Common Publications
Mei Zhong, PhD
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View 4 Common Publications
In-Hyun Park, PhD
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View 2 Common Publications
Patrick Gallagher, MD, BS
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View 2 Common Publications

Publications

2025

Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors
Karatepe K, de Faria B, Zhang J, Chen X, Pinto H, Fyodorov D, Sefik E, Willcockson M, Flavell R, Skoultchi A, Guo S. Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2509412122. PMID: 41118213, PMCID: PMC12582276, DOI: 10.1073/pnas.2509412122.
Peer-Reviewed Original Research
MeSH Keywords
Molecular basis of cell fate plasticity — insights from the privileged cells
Scalf S, Wu Q, Guo S. Molecular basis of cell fate plasticity — insights from the privileged cells. Current Opinion In Genetics & Development 2025, 93: 102354. PMID: 40327951, PMCID: PMC12277062, DOI: 10.1016/j.gde.2025.102354.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements

Academic Achievements & Community Involvement

Honors

honor
Director's New Innovator Award (DP2)
10/01/2016National Award
Details
honor
Charles H. Hood Foundation Child Health Research Award
03/01/2016Regional Award
Details
honor
Gilead Sciences Research Scholar in Hematology/oncology
12/05/2015International Award
Details
honor
Yale Center for Clinical Investigation Scholar
09/01/2014Yale University Award
Details

News & Links

Media

Growing colonies during Yamanaka reprogramming captured by live-cell imaging. Green color indicates pluripotency (Oct4:GFP). Red color indicates G1 cell cycle phase (FUCCI).
Cell Fate, Pluripotent Stem Cells & Probability - The Guo Lab at Yale School of Medicine
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News

Related Links
- Visit Guo lab

Get In Touch

Contacts

shangqin.guo@yale.edu

Academic Office Number

203.737.6411

Mailing Address

Cell Biology

10 Amistad St.

New Haven, CT 06520-8005

United States

Events

Nov 202619Thursday

Yale Only
1:00 PM2:00 PM
David Beck, PhD, MD
Yale Cell Biology Seminar Series
"Defining Mechanisms Underlying VEXAS Syndrome"
101 College Street
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Appointments

Contact Info

Titles

Appointments

Cell Biology

Other Departments & Organizations

Education & Training

Overview

Medical Research Interests

ORCID

Guo lab

Research at a Glance

Yale Co-Authors

Jun Lu, PhD

Cynthia M. Megyola

Diane Krause, MD, PhD

Mei Zhong, PhD

In-Hyun Park, PhD

Patrick Gallagher, MD, BS

Publications

2025

2023

2022

2021

2020

Honors

Director's New Innovator Award (DP2)

Charles H. Hood Foundation Child Health Research Award

Gilead Sciences Research Scholar in Hematology/oncology

Yale Center for Clinical Investigation Scholar

Media

ips3_Pos14_3x3_CP1_Mix_Time_0408

News

Women’s Health Research at Yale Funds Projects on Obesity and Ovarian Aging, Diabetes, Cancers, and Autoimmunity

From Fundamental Biology to Treatments for Disease, Stem Cells are Engines of Discovery

Related Links

Contacts

Events

Yale Cell Biology Seminar Series