Recent Publications

Impact of age on outcomes after CD19 CAR T-cell therapy for large B-cell lymphomas.Mirza AS, Hosing C, Foss F, Kim S, Moskop A, Oloyede T, Abid MB, Afrough A, Ahmed S, Badar T, Barba P, Bhatt VR, Brown VI, Dahiya S, Deol A, Epperla N, Ganguly S, Grover NS, Hashmi H, Hashmi S, Hematti P, Hildebrandt GC, Hill JM Jr, Hossain NM, Ibrahim U, Johnson PC, Kharfan-Dabaja MA, Krem MM, Lekakis LJ, Maziarz RT, Murthy HS, Riedell PA, Salas MQ, Shouse G, Strouse C, Thakar MS, Turtle CJ, Woolfrey A, Wudhikarn K, Yared JA, Pasquini MC, Gowda L. Blood Neoplasia. 2026 May; 2025 Nov 25. PMID: 41867486.
Comparative effectiveness of HMA with venetoclax vs intensive chemotherapy in AML with very high-risk cytogenetics.Aguirre LE, Bewersdorf JP, Liu Y, Shallis RM, Boussi L, Zucenka A, Garciaz S, Bystrom RP, DeAngelo DJ, Stone RM, Luskin MR, Garcia JS, Winer ES, Ling K, Chen EC, Wadleigh M, Berton G, Stein EM, Goldberg AD, Mendez L, Zeidan AM, Sallman DA, Shimony S, Stahl M. Blood Neoplasia. 2026 May; 2026 Jan 28. PMID: 41859348.
Epigenetic activation of EBV BGLF4 determines antiviral-based regimen response in EBV+CNS lymphoproliferative disease.Weigel C, Klimaszewski HL, Tounkara F, Addissie S, Schlotter S, Pray B, Dugan JP, Haverkos BM, Villagomez L, Lustberg M, Porcu P, Voorhees T, Ambinder RF, Kenney SC, Fingeroth J, Delecluse HJ, Caligiuri MA, Alinari L, Bumgardner G, Oakes CC, Baiocchi RA. Blood Neoplasia. 2026 May; 2026 Jan 28. PMID: 41808730.
Emerging biomarkers in melanoma: Bridging molecular discovery and precision oncology.Xu S, Huang Z, Li Y, Lu L, Ma W. Cancer Lett. 2026 May 1; 2026 Feb 22. PMID: 41734832.
Advancing substance use disorder biology by studying underlying gene x environment interactions.Sidamon-Eristoff AE, Rivera-Hernandez M, Huckins LM, Montalvo-Ortiz JL, Brennand KJ. Curr Opin Genet Dev. 2026 Apr; 2026 Feb 16. PMID: 41702263.
RBC Alloimmunization Impacts Pediatric Sickle Cell Disease Transplant Outcomes and Transfusion Burden: A STAR Registry Report.Inam Z, Stenger E, John TD, Liu K, Gillespie S, Shah R, Chellapandian D, Bhatia M, Chaudhury S, Eckrich MJ, Guilcher GMT, Hendrickson JE, Hulbert ML, Jaroscak JJ, Kasow KA, Camacho-Bydume C, Ngwube A, Olson TS, Rangarajan HG, Horan JT, Krishnamurti L, Shenoy S, Abraham A, Nickel RS. Am J Hematol. 2026 Apr; 2026 Jan 12. PMID: 41524608.
Global burden of lower respiratory infections and aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.Lancet Infect Dis. 2026 Apr; 2025 Dec 15. PMID: 41412141.
3D genetic architecture of schizophrenia risk across three neuronal subtypes.Powell SK, Liao W, Ghorbani S, Rigat R, O'Shea C, Kammourh S, Elahi R, Infante D, Deans PJM, Le DJ, Agarwal P, Qiang Seow W, Balafkan N, Wang KC, Akbarian S, Brennand KJ. Mol Psychiatry. 2026 Apr; 2025 Nov 28. PMID: 41310180.
Molecular-Based Ecosystem to Improve Personalized Medicine in Chronic Myelomonocytic Leukemia.Lanino L, Hunter AM, Gagelmann N, Robin M, Dall'Olio D, Flamigni A, Sala C, Gurnari C, Wang YH, Pleyer L, Xicoy B, Montalban-Bravo G, Shih LY, Alsugair A, Fathima S, Gregorio C, Rollo C, Palomo L, Platzbecker AS, Asti G, Itzykson R, Sallman DA, Fariselli P, Kern W, Garcia-Manero G, Platzbecker U, Solé F, Diez-Campelo M, Maciejewski J, Bejar R, Thol F, Kroger N, Savona M, Fenaux P, Sanz G, Kordasti S, Santini V, Fontenay M, Zeidan AM, Komrokji RS, Haferlach T, Germing U, Castellani G, D'Amico S, Patnaik M, Ieva F, Solary E, Tefferi A, Padron E, Della Porta MG. J Clin Oncol. 2026 Mar 27; 2026 Mar 27. PMID: 41894646.
Continuous intravenous infusion of human mesenchymal stromal cell-derived small extracellular vesicles in spinal cord injured rat modulates extracellular matrix and has greater therapeutic efficacy than multiple single injections.Nakazaki M, Lankford KL, Toyoshima M, Tanaka Y, Sumida TS, Kocsis JD. Neurotherapeutics. 2026 Mar 26; 2026 Mar 26. PMID: 41894999.
Metabolic dysfunction-associated steatotic liver disease and acute leukemias - a literature review and future directions.Salah T, Stahl M, Bewersdorf JP. Leuk Lymphoma. 2026 Mar 25; 2026 Mar 25. PMID: 41879616.
Pharmaco-behavioral profiling identifies suppressors of autism gene-associated phenotypes in zebrafish.Jamadagni P, Dai Y, Liu Y, Weinschutz Mendes H, Pruitt A, Khan S, Yang L, Huang TC, Huang X, Deans PJM, Balafkan N, Zhao D, Xu G, Liu Y, Li N, Wu W, Fitzpatrick SE, Neelakantan U, Chen T, Szialta C, Jin DS, Lacadie CM, Umlauf S, Papademetris X, Surovtseva YV, Brennand KJ, Wang Z, Hoffman EJ. Proc Natl Acad Sci U S A. 2026 Mar 24; 2026 Mar 16. PMID: 41838920.
Glutamine metabolism tunes myeloid responses to drive resolution of inflammation during skin repair.Xu Y, Forni MF, Benvie A, Castano N, King D, Sun Q, Siebel S, Tran VA, Kibbey RG, Miller-Jensen K, Horsley V. Cell Rep. 2026 Mar 24; 2026 Feb 18. PMID: 41712383.
Cannabidiol in Developmental Epilepsy: Organoid-Guided Precision Medicine Across Critical Neurodevelopmental Windows.Joo J, Yang WS, Koh HJ. Int J Mol Sci. 2026 Mar 23; 2026 Mar 23. PMID: 41898755.
Tracheal Regeneration: Recent Progress in the Application of Stem Cells in Tracheal Bioengineering.Ganji F, Le Billan F, Haykal S, Karoubi G. Int J Mol Sci. 2026 Mar 23; 2026 Mar 23. PMID: 41898750.
Drift of positional identity drives reproductive aging in a long-lived regenerative animal.Verdesca A, Poulet A, Bales M, van Wolfswinkel JC. Curr Biol. 2026 Mar 23; 2026 Mar 23. PMID: 41875878.
MASTR-seq enables multiplexed analysis of short tandem repeats with sequencing.Su C, Ryu HS, Chandradoss KR, Malachowski T, Boya R, Zhou L, Nguyen HE, Mazzoni EO, Brennand KJ, Phillips-Cremins JE. Cell Rep Methods. 2026 Mar 23; 2026 Mar 17. PMID: 41850290.
Clinical strategies for leukemia management: Recommendations from the Bridging the Gaps in Hematology Oncology Consensus Conference 2025.Carraway HE, DeAngelo DJ, Wang ES, Komrokji RS, Perl AE, Zeidan A, Brunner A, Lai C, Park JH, Zeidner JF, Weeks L, Luskin MR, Chandhok NS, Loghavi S. Leuk Res. 2026 Mar 20; 2026 Mar 20. PMID: 41895012.
Establishing Area-Specific Brain Organoids Through Transcription Factor-Mediated Patterning.Kim J, Jang YS, Lee M, Choi NY, Jung Y, Lim J, Kwak TH. Biology (Basel). 2026 Mar 19; 2026 Mar 19. PMID: 41892247.
Omics insights into MYBL2-promoted cancer stem-like cells driving ferroptosis resistance in hepatocellular carcinoma.Chen Y, Li X, Luo C, Lin G, Zhou X, Wen Z, Su H, Meng W, Chen C, Lu J, Luo X, Jiang D, Liu H, Ning Z, Chen Y, Tam PK, Pan X. J Adv Res. 2026 Mar 19; 2026 Mar 19. PMID: 41864611.
Breast Tissue Reconstruction Strategies: A Tissue Engineering Approach.Stoian A, Duru Ç, Chogan F, Biniazan F, Temple B, Karoubi G, Haykal S. Tissue Eng Part B Rev. 2026 Mar 18; 2026 Mar 18. PMID: 40910925.
Spatial profiling of patient-matched HER2 positive gastric cancer reveals resistance mechanisms to targeted therapy.Sheng T, Sundar R, Srivastava S, Ong X, Tay ST, Ma H, Uchihara T, Lian BSX, Hagihara T, Kong MS, Xu C, Ho SWT, Huang KK, Tan ALK, Ng MSW, Toh J, Ng CSY, Nasca V, Pircher CC, Randon G, Giordano S, Corso S, Lum JHY, Teh M, Zhao JJ, So JBY, Sabella G, Prabhakar S, Lee J, Yong WP, Ng MCH, Shitara K, Gasparello J, Fassan M, Pietrantonio F, Tan P. Gut. 2026 Mar 6; 2026 Mar 6. PMID: 41167802.
Gene-corrected regulatory T cell therapy for IL2RA deficiency.Ha AS, Kalter N, Rosenberg M, Acevedo LA, Liang B, Liu W, Paruthiyil S, Sinha M, Vu A, Nguyen V, Qi Z, Krishnappa N, Shu J, Yu J, Catanzaro J, Bluestone JA, Tang Q, Urnov FD, Marson A, Hendel A, Herold KC, Shy BR, Esensten JH. Mol Ther. 2026 Mar 4; 2025 Dec 9. PMID: 41376159.
Haplotype editing with CRISPR-Cas9 as a therapeutic approach for dominant-negative missense mutations in NEFL.Dua PH, Simon BMJ, Marley CBE, Feliciano CM, Watry HL, Cowan QT, Steury D, Abraham A, Gilbertson EN, Ramey GD, Capra JA, Conklin BR, Judge LM. Mol Ther. 2026 Mar 4; 2025 Nov 19. PMID: 41267399.
Intranasal administration of human mesenchymal stromal cell-derived small extracellular vesicles delays disease progression in the SOD1(G93A) mouse model.Hirota R, Lankford KL, Nakazaki M, Toyoshima M, Kocsis JD. Mol Brain. 2026 Mar 3; 2026 Mar 3. PMID: 41776544.
Global burden of adverse effects of medical treatment from 1990 to 2021: a Global Burden of Disease Study 2021.Korean J Intern Med. 2026 Mar; 2026 Mar 1. PMID: 41850226.
Global, regional, and national burden of breast cancer among females, 1990-2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023.Lancet Oncol. 2026 Mar. PMID: 41785894.
Piezo1-dependent activation of stromal cells ignites muscle inflammation in exercise and injury and is associated with inflammaging.Langston PK, Vijaya Raghavan J, Benoist C, Mathis D. Nat Immunol. 2026 Mar; 2026 Mar 3. PMID: 41775886.
Concurrent pulmonary aspergillosis and phaeohyphomycosis due to Verruconis spp. in a stem cell transplant recipient with chronic graft-versus-host disease.Carreras X, Machiavello Roman F. Med Mycol Case Rep. 2026 Mar; 2026 Jan 16. PMID: 41624956.
tRNA m(1)A modification orchestrates STING translation in macrophages to enhance antitumor immunity and CAR-macrophage immunotherapy.Wang X, Wang X, Li H, Liu S, Lu Y, Chen H, Cai X, Su S, Li B, Liu R, Hu W, Zhu X, Zhang J, Ye Y, Li HB. Cell Mol Immunol. 2026 Mar; 2026 Jan 14. PMID: 41535541.
IDR-induced CAR condensation improves the cytotoxicity of CAR-Ts against low-antigen cancers.Zhang X, Xiao Q, Zeng L, Hashmi F, Sato K, Hartwich TMP, Mansolf M, Yang-Hartwich Y, Su X. Nat Chem Biol. 2026 Mar; 2025 Sep 29. PMID: 41023404.
A modular vaccine platform for optimized lipid nanoparticle mRNA immunogenicity.Fang Z, Monteiro VS, Oh C, Janabi KA, Romero L, Ahsan N, Yang L, Peng L, DiMaio D, Lucas C, Chen S. Nat Biomed Eng. 2026 Mar; 2025 Aug 25. PMID: 40855125.
Mast cell extracellular granules are bioactive condensates assembled by heparin and polyamine.Xiong Y, Tomares DT, Guo J, Sato K, Zeng L, Tian Y, Su M, Albis A, Pant A, Pappu RV, Su X. Nat Chem Biol. 2026 Feb 27; 2026 Feb 27. PMID: 41760814.
OR7A10 GPCR engineering boosts CAR-NK therapy against solid tumours.Yang L, Renauer PA, Tang K, Saskin J, Zhou L, Zou C, Lee SH, Fox M, Johnson-Noya S, Weiss B, Deng S, Fang P, Chen B, Sferruzza G, Fooladi S, Zhao K, Park D, Zhang F, Tu J, Chen J, Moliterno J, Gunel M, Peng L, Chen S. Nature. 2026 Feb 25; 2026 Feb 25. PMID: 41741641.
No clear benefit of cellular therapy consolidation for patients achieving remission after post-HCT AML relapse.Murdock HM, Kim HT, Maurer K, Kelkar A, Shapiro RM, Gooptu M, Romee R, Nageshwar PK, Garrity HM, Shimony S, Luskin MR, Winer ES, Vedula RS, Stahl M, Chen EC, Volpe V, Garcia JS, Wadleigh M, DeAngelo DJ, Stone RM, Wu CJ, Cutler CS, Koreth J, Ritz J, Antin JH, Ho VT, Nikiforow S, Soiffer RJ. Blood Adv. 2026 Feb 24. PMID: 41172235.
Non-invasive ovulation tracking enables genetic engineering in wild rodents.Buchthal J, Chory EJ, Hill Z, Dennison C, Tu B, Wierenga RP, Çevrim Ç, Golas S, Meier G, Lan TCT, Chung H, Boucher M, Telford SR, McKinley KL, Markoulaki S, Jaenisch R, Esvelt KM. Cell Rep Methods. 2026 Feb 23; 2026 Feb 17. PMID: 41709464.
Thorn specification in citrus plants by an SHI/STY family transcription factor.Zheng Q, Zhou S, Irish VF, Zhang F. Curr Biol. 2026 Feb 23; 2026 Feb 2. PMID: 41633363.
Estradiol modulates neuronal network hyperexcitability in select NDD risk genes.Pruitt A, Yang L, Lee S, Balafkan N, Seah C, Dai Y, Davidson E, Khan S, Sen A, Liu J, Wood I, Xu G, Huang X, Carlson M, Zhao D, Jamadagni P, Dossou G, Retallick-Townsley K, Li X, Deans PJM, Garcia MF, Gao H, Wang Z, Huckins LM, Hoffman EJ, Brennand KJ. bioRxiv. 2026 Feb 18; 2026 Feb 18. PMID: 41757108.
G-CSF for Mobilizing CD34(+) Cells in Individuals With SCD: A Word of Caution.Sharma A, Abraham A, Bhatia M, Cancio M, Chaudhury S, Corbacioglu S, Guilcher GMT, Gupta AO, Hanna R, Heeney MM, John T, Krishnamurti L, LaBelle JL, Rangarajan HG, Shenoy S, Stenger E, Strunk C, Fitzhugh CD. Am J Hematol. 2026 Feb 18; 2026 Feb 18. PMID: 41705621.
Rethinking the microenvironment's role in chemical-induced malignancy.Bisson WH, Currie RA, Lim EL, Mlynarczyk C, Tokar EJ, Colacci A, Colacino JA. Toxicol Sci. 2026 Feb 18. PMID: 41405843.
Ex vivo expansion of melanoma tumor infiltrating lymphocytes leads to a dominant exhausted T cell population with lack of memory markers.Coppola G, Kerr S, Cha PC, Bersenev A, Olino K, Kluger HM, Sznol M, Weiss SA, Bosenberg MW, Kleinstein SH, Krause DS, Hurwitz ME, Katz SG. Cancer Immunol Res. 2026 Feb 13; 2026 Feb 13. PMID: 41686210.
Hormonal control of postmitotic neuronal identity.Wani AR, Ashraf R, Woerner R, Marriner Z, Velasquez M, Azam T, Joo Q, Dus M, Syed MH. bioRxiv. 2026 Feb 13; 2026 Feb 13. PMID: 41659434.
Early time to relapse as a survival prognosticator in nodal mature T-cell lymphomas: results from the PETAL consortium.Sorial MN, Malpica Castillo LE, Chiattone C, Julia E, Bachy E, Barta SK, Stuver R, Jacobsen E, Federico M, Jain H, Prince HM, Foss F, Zinzani PL, Okatani T, Kim WS, Verburgh E, Al-Mansour M, Cabrera ME, Bhagat G, Shen C, Jain S. Blood. 2026 Feb 12. PMID: 41347825.
Informed shared decision-making or rigid eligibility and exclusion criteria for gene therapy for sickle cell disease?Krishnamurti L, Olafimihan A, Hsu LL. Blood Adv. 2026 Feb 10. PMID: 41092461.
Therapeutic Potential of Extracellular Vesicles: From Biogenesis, Isolation and Molecular Characterization to Addressing Translational Gaps and Regulatory Barriers.Primorac D, Brlek P, Bulić L, Hrvatin N, Škaro V, Projić P, Glavan M, Oleru I, Rocheteau P, Tremolada C, DeMers A, Ambach MA, Buford D, Knežević T, Kouroupis D, Conforti C, Kimbrough DW, Schnorr RP, Williams L, Vaiciuleviciute R, Fortuna Ž, Oprešnik L, Curk B, Knežević M, Kalan Živčec G, Hrkać A, Tsoukas D, Uzieliene I, Pachaleva J, Bernotiene E, Barbato K, Patel N, Guanche ID, Badiavas EV, Mešić J, Medić Flajšman A, Milanič R, Klarić D, Kalodimou VE, Allegri M, Brachmann J, Toh WS, Delgado ND, Mobasheri A. Int J Mol Sci. 2026 Feb 9; 2026 Feb 9. PMID: 41751812.
Single-cell Spatial Multiomics: Technologies, Methods, and Biological Applications.Xing D, Fan R, Zhao F. Genomics Proteomics Bioinformatics. 2026 Feb 9; 2026 Feb 9. PMID: 41660845.
Disseminated mucormycosis.Radcliffe CV, Tremblay EE, Machiavello Roman FJ. IDCases. 2026; 2026 Feb 7. PMID: 41717056.
TRPM7 Deficiency Protects Against Myocardial Ischemia-Reperfusion Injury by Regulating Intracellular Zn(2+) Homeostasis.Li X, Li X, Li CX, Feng J, Yue Z, Yan J, Matsushita M, Qyang Y, Runnels LW, Ai X, Yue L. Circulation. 2026 Feb 6; 2026 Feb 6. PMID: 41645903.
Biochemical Reconstitution and FRAP Analysis of Membrane-Associated Condensates on Supported Lipid Bilayers.Zeng L, Su X. Bio Protoc. 2026 Feb 5; 2026 Feb 5. PMID: 41675989.
Mechanical Stretch Disrupts Calcium Dynamics and Redistributes Piezo1 in Human Astrocytes.Shiravi S, Chakka A, Xiao X, Garcia MF, Yufa A, Mitevska A, Seah C, Gao H, Huckins LM, Brennand KJ, Finan JD. Ann Biomed Eng. 2026 Feb 5; 2026 Feb 5. PMID: 41642456.
Modelling chemotaxis of branched cells in complex environments provides insights into immune cell navigation.Liu J, Ron JE, Rinaldi G, Williantarra I, Georgantzoglou A, Vries I, Sixt M, Sarris M, Gov NS. PLoS Comput Biol. 2026 Feb; 2026 Feb 3. PMID: 41632822.
Training Tomorrow's Leaders in Cancer Immunology.Tan Y, Kim BJ, Mujal AM, Chen ACY, Weis AM, Bergaggio E, Micevic G, Xie H, Park JS, Hor JL, Papanicolaou M, Shobaki N, Domizi P, Delconte RB, Vendramin R, Hegde S, Han S, Su Y, Hacohen N. Cancer Immunol Res. 2026 Feb 3. PMID: 41524276.
Comparison of Outcomes With Novel Versus Traditional Chemotherapy Regimens for Relapsed and Refractory Classical Hodgkin Lymphoma.Ermann D, Vardell V, Zacholski E, Fegley A, Modi D, Fedak K, Sundaram S, Rajeeve S, Goyal G, Hatic H, Torka P, Ba Aqeel S, Borogovac A, MacDougall K, Kothari S, Kress A, Travers E, Chilakamarri N, Brem E, Ayyappan S, Sigmund A, Bond D, Fitzgerald L, Wagner C, Hu B, Stephens DM, Shah H. Clin Lymphoma Myeloma Leuk. 2026 Feb 2; 2026 Feb 2. PMID: 41763973.
Mutant p53 promotes clonal hematopoiesis by generating a chronic inflammatory microenvironment.Chen S, Barajas S, Vemula S, Yang Y, Simpson E, Gao H, Li R, Behzadnia F, Nabinger SC, Schmitz DA, Chen H, Cai W, Xiao S, Luo R, Amin MA, Capitano ML, Ropa JP, Fahey A, Zhou S, Mays TM, Sotelo M, Pan H, Hu SK, Veranga S, Ali M, Shumilina M, Kapur R, Ren K, Jia Y, Liu H, Khan I, Abaza Y, Altman JK, Eklund EA, Godley LA, Zhang CR, Ji P, Masters SL, Croker BA, Boswell HS, Sandusky GE, Gao Z, Mayo LD, Savage SA, Halene S, Dou Y, Platanias LC, Sukhanova M, Liu Y, Abdel-Wahab O, Liu Y. J Clin Invest. 2026 Feb 2; 2025 Dec 30. PMID: 41468163.
A circadian checkpoint relocates neutrophils to minimize injury.Aroca-Crevillén A, Martín-Salamanca S, Torres LS, Crainiciuc G, Sicilia J, Peñaloza-Martínez E, Rosillo N, Molina-Moreno M, Adrover JM, Rubio-Ponce A, Vicanolo T, Liu X, Wichapong K, Núñez V, Balabanian K, Bachelerie F, Sancho D, Casanova-Acebes M, Ortiz-Pérez JT, Moro MÁ, Bueno H, Nicolaes GAF, Hidalgo A. J Exp Med. 2026 Feb 2; 2025 Dec 12. PMID: 41385080.
Pharmacologic progress in higher-risk MDS: an uphill battle.Mina A, Zeidan AM. Expert Opin Pharmacother. 2026 Feb; 2026 Mar 18. PMID: 41804943.
PFKM governs metabolic shifts throughout skeletal muscle differentiation.Campos M, Nguyen ST, Kong X, Yang Y, Watson RL, Gromova A, Livelo CR, Franco CN, Cabral JE, Seabrook LJ, Dai S, Liu Y, Zhou M, Hanse EA, Sumigray K, La Spada AR, Seldin MM, Plikus MV, Nicholas DA, McNulty R, Kong M, Yokomori K, Albrecht LV. Nat Metab. 2026 Feb; 2026 Feb 24. PMID: 41735679.
Where Do We Stand for Nerve Regeneration and Functional Recovery After Vascularized Composite Allotransplantation?Mathieu O, Knoedler L, Schaschinger T, Fenske J, Klimitz FJ, Jeljeli M, Cetrulo CL Jr, Lellouch AG. Microsurgery. 2026 Feb. PMID: 41665096.
Impact of European LeukemiaNet-guided postremission therapy on outcomes of patients with AML from 2010 to 2022.Berdel AF, Ronnacker J, Wenge DV, Kolloch LJ, Berning P, Angenendt L, Brix TJ, Westermann A, Wethmar K, Kessler T, Kerkhoff A, Mesters RM, Reicherts C, Mikesch JH, Berdel WE, Lenz G, Schliemann C, Stelljes M. Blood Neoplasia. 2026 Feb; 2025 Nov 6. PMID: 41509995.
Pertpy: an end-to-end framework for perturbation analysis.Heumos L, Ji Y, May L, Green TD, Peidli S, Zhang X, Wu X, Ostner J, Schumacher A, Hrovatin K, Müller M, Chong F, Sturm G, Tejada A, Dann E, Dong M, Pinto G, Bahrami M, Gold I, Rybakov S, Namsaraeva A, Moinfar AA, Zheng Z, Roellin E, Mekki I, Sander C, Lotfollahi M, Schiller HB, Theis FJ. Nat Methods. 2026 Feb; 2025 Dec 31. PMID: 41476114.
WHIM syndrome: from mechanism to targeted therapy - advances shaping clinical care.Miller RZ, Geier CB, Bledsoe JR, Pereira J, Walter JE. Curr Opin Allergy Clin Immunol. 2026 Feb 1; 2025 Dec 12. PMID: 41451822.
Uncovering the role of LINE-1 in the evolution of lung adenocarcinoma.Zhang T, Zhao W, Wirth C, Díaz-Gay M, Yin J, Cecati M, Marchegiani F, Hoang PH, Leduc C, Baine MK, Travis WD, Sholl LM, Joubert P, Sang J, McElderry JP, Antony M, Klein A, Khandekar A, Hartman C, Rosenbaum J, Colón-Matos FJ, Miraftab M, Saha M, Lee OW, Jones KM, Caporaso NE, Wong MP, Leung KC, Hsiung CA, Chen CY, Edell ES, Santamaría JM, Schabath MB, Yendamuri SS, Manczuk M, Lissowska J, Świątkowska B, Mukeria A, Shangina O, Zaridze D, Holcatova I, Mates D, Milosavljevic S, Savic M, Bossé Y, Rothberg BEG, Christiani DC, Gaborieau V, Brennan P, Liu G, Hofman P, Homer R, Yang SR, Pesatori AC, Consonni D, Yang L, Zhu B, Shi J, Brown K, Rothman N, Chanock SJ, Alexandrov LB, Choi J, Cardelli M, Lan Q, Nowak MA, Wedge DC, Landi MT. Nature. 2026 Feb; 2025 Dec 10. PMID: 41372401.
The global epidemiology of acute myeloid leukaemia.El Chaer F, Bewersdorf JP, Stahl M, Zeidan AM. Nat Rev Clin Oncol. 2026 Feb; 2025 Dec 5. PMID: 41350446.
TSC tunes progenitor balance and upper-layer neuron generation in neocortex.Casingal CR, Nakagawa N, Yabuno-Nakagawa K, Meyer C, Liu S, Gkini V, Cho SJ, Skarica M, Liang D, Simon JM, Matoba N, Mallick A, Singla R, Park J, Huang CW, Wilson H, Lee J, Ghashghaei HT, Stuber GD, Heikinheimo O, Namba T, Stein JL, Anton ES. Nature. 2026 Feb; 2025 Dec 3. PMID: 41339559.
CRS or ICANS Are Rare Beyond 2 Weeks After Lisocabtagene Maraleucel Infusion: Data From Clinical Trials and the Real-World Setting.Hunter BD, Lunning M, Shadman M, Ahmed S, Abramson JS, Perales MA, Ahmed N, Mirza AS, Isufi I, Frigault MJ, Crombie JL, Miklos DB, Vasconcelos A, Crotta A, Bernasconi D, Roy D, Bleickardt E, Pasquini MC, Kamdar M. Transplant Cell Ther. 2026 Feb; 2025 Oct 24. PMID: 41235976.
The Pediatric Clinician's Approach to Referring Children and Adolescents with Sickle Cell Disease for Potentially Curative Therapies.John TD, Krishnamurti L. Pediatr Clin North Am. 2026 Feb; 2025 Sep 26. PMID: 41207739.
A Human Neural Tube Model Using 4D Self-Folding Smart Scaffolds.Dell'Amico C, Chiesa I, Toffano A, Esposito A, Mancini P, Magliaro C, Louvi A, De Maria C, Onorati M. Adv Healthc Mater. 2026 Feb; 2025 Oct 23. PMID: 41126690.
Acute Toxicities of Bone Marrow Donation in Unrelated Donors with Sickle Cell Trait: A Center for International Blood and Marrow Transplantation Research Analysis.Farhadfar N, Bo-Subait S, Schmidt G, Logan B, Aljurf M, Badawy S, Beitinjaneh A, Gowda L, Kasow KA, Seftel M, Sharma A, Rangarajan HG, Herr M, Battiwalla M, Shaw BE, Stefanski HE. Transplant Cell Ther. 2026 Feb; 2025 Oct 8. PMID: 41072772.
Advanced tissue-engineered pulsatile conduit using human induced pluripotent stem cell-derived cardiomyocytes.Luo H, Anderson CW, Li X, Lu Y, Hoareau M, Xing Q, Fooladi S, Liu Y, Xu Z, Park J, Fallon ME, Thomas J, Gruber PJ, Elder RW, Mak M, Riaz M, Campbell SG, Qyang Y. Acta Biomater. 2026 Feb; 2025 Jun 27. PMID: 40582540.
Dynamic heterogeneity towards drug resistance in AML cells is primarily driven by epigenomic mechanism unveiled by multi-omics analysis.Zhang Y, Lu Y, Mai L, Wen Z, Dai M, Xu S, Lin X, Luo Y, Qiu Y, Chen Y, Dong Z, Chen C, Meng W, Luo X, Lin G, Tam PKH, Pan X. J Adv Res. 2026 Feb; 2025 May 21. PMID: 40409464.
Hypomethylating agents plus venetoclax versus intensive chemotherapy in acute myeloid leukemia with chromosome 5 and 7 abnormalities.Boussi L, Bewersdorf JP, Liu Y, Shallis RM, Aguirre LE, Bystrom RP, Zucenka A, Garciaz S, DeAngelo DJ, Stone RM, Luskin MR, Garcia JS, Winer ES, Chen EC, Wadleigh M, Berton G, Ling K, Zeidan AM, Stein EM, Shimony S, Goldberg AD, Stahl M. Haematologica. 2026 Jan 29; 2026 Jan 29. PMID: 41609030.
Mechanisms of transcriptional regulation of CCR5, which is the co-receptor for R5-tropic HIV and is also involved in other disease processes.Wang L, Akisa SV, Sutton R. Biochem Soc Trans. 2026 Jan 28. PMID: 41608770.
Identification of Wnt-regulated genes that are repressed by, or independent of, β-catenin.Liu S, Haghani S, Petretto E, Madan B, Harmston N, Virshup DM. FEBS J. 2026 Jan 28; 2026 Jan 28. PMID: 41601419.
Activating Ras-MAPK pathway variants drive hippocampal clonal competition in human epilepsy.Khoshkhoo S, Bae M, Wang Y, Tillett A, Ramirez RB, Finander B, Egan ED, Marx L, Patel D, Zhou Z, Chahine Y, Chhouk B, Zoullas SM, Lai A, Coras R, Bielle F, Navarro V, Mathon B, Valiante TA, Moradi Chameh H, Gao AF, Krings T, Gooley S, Hildebrand MS, Bulluss K, Clark J, Morokoff AP, King JA, Todaro M, Kwan P, O'Brien TJ, Berkovic SF, Scheffer IE, Perucca P, Lapinskas E, Rolston JD, Cosgrove GR, Sarkis RA, D'Gama AM, Alexadrescu S, Yang E, Poduri A, Richardson RM, Erson-Omay EZ, DeLanerolle N, Spencer DD, Brown KS, Miller MB, Roberts AE, Santos LN, Kontaridis MI, Bien CG, Blacklow SC, Kahle KT, Blümcke I, Huang AY, Lee EA, Walsh CA. bioRxiv. 2026 Jan 27; 2026 Jan 27. PMID: 41659639.
Epidermal growth factor receptor regulates Beclin-1 in hyperoxic acute lung injury.Harris ZM, Korde A, Khoury J, Manning EP, Stanley G, Shin Y, Mitchell K, von der Schulenburg A, Sun Y, Hu B, Shin HJ, Joerns J, Clark B, Placek L, Unutmaz D, Moldobaeva A, Sharma L, Sauler M, Rajagopalan G, Zhang X, Wang H, Ghaedi M, Kang MJ, Koff JL. BMJ Open Respir Res. 2026 Jan 27; 2026 Jan 27. PMID: 41592865.
Baseline IPSS-M vs Pretransplant Risk Downstaging as Prognostic Determinants in MDS Undergoing Allogeneic Transplantation.Aguirre LE, Kim HT, Elmariah H, Frumm SM, Kelkar AH, Ho VT, Gooptu M, Koreth J, Shapiro RM, Romee R, Nikiforow S, Antin JH, Soiffer RJ, Shimony S, Luskin MR, Garcia JS, Chen EC, Wadleigh M, Winer ES, Stone RM, DeAngelo DJ, Al-Ali N, Sallman DA, Kuykendall AT, Sweet KL, Lancet JE, Padron E, Chan O, Xie Z, Cutler CS, Komrokji RS, Stahl MF. Blood Adv. 2026 Jan 26; 2026 Jan 26. PMID: 41587470.
Dose-dependent activation of the Hippo pathway by Type I and Type III interferons suppresses tissue repair by human bronchial epithelial cells.Subramaniam KV, Lim HJ, Wang B, Mihaylova VT, Thompson EN, Krause DS, Foxman EF. PLoS Biol. 2026 Jan; 2026 Jan 26. PMID: 41587178.
Anti-CD3 mAb treatment reshapes infiltrating T and β cells in the islets in autoimmune diabetes.Wu Y, Spurrell M, Lledó-Delgado A, Deng S, Wang D, Liu Y, Barkestani MN, Perdigoto AL, Herold KC. JCI Insight. 2026 Jan 23; 2026 Jan 23. PMID: 41574610.
A two-tier framework for responsible research on human embryo models.De Los Angeles A, Bayne T, Benvenisty N, Deng H, Fujita M, Ji W, Latham S, Li T, Liu P, Loh YH, Lunshof J, Pei D, Pho N, Silva JCR, Ka Ki Tam TT, Tao T, Trounson A, Xu S, Yu L, Koplin J, Regenberg A, Sugaya K, Savulescu J, Zernicka-Goetz M, Lovell-Badge R. Cell. 2026 Jan 22. PMID: 41576917.
Natural ovulation versus programmed regimens before frozen embryo transfer in ovulatory women: multicentre, randomised clinical trial.Wei D, Qin Y, Sun Y, Yan J, Zhao H, Guan Y, Tan J, Guo T, Wang Z, Gong F, Hao C, Ma X, Zhang C, Zhang A, Geng L, Sun M, Li X, Ling X, Lu Q, Bao H, Chao L, Huang W, Shi Q, Zhao J, Lu Y, Wu S, Zhang S, Wang J, Guo M, Sun X, Ma Y, Wu Q, Li Y, Ou X, Fang Z, Chen J, Hao G, Zhang H, Legro RS, Chen ZJ. BMJ. 2026 Jan 21; 2026 Jan 21. PMID: 41565309.
Postnatal liver B cell precursors contribute to the establishment of a mature B cell pool in secondary lymphoid organs in mice.Mafra K, de Oliveira MG, Nakagaki BNL, Porto Pedrosa MLM, Lanser TB, da Silva P, Antunes MM, da Silva Júnior WF, Mattos MS, Lopes ME, da Rocha Fernandes G, Cunha TM, Pinto de Paula CM, David BA, Rastogi T, Yang Z, Babar MU, Konnikava L, Caetano AM, Vale AM, Kubes P, Libreros S, Rezende RM, Menezes GB. J Immunol. 2026 Jan 21. PMID: 41138221.
Peptidoglycan architecture dictates protein interactions, tissue tropism, and arthritis in the Lyme disease spirochete Borrelia burgdorferi.Ahmad SS, Ebohon O, McClune ME, Trimble RN, Kellogg CN, Booth CJ, Zückert WR, Jutras BL. PLoS Pathog. 2026 Jan; 2026 Jan 20. PMID: 41557633.
Fertilization with Protamine-2 deficient sperm triggers abnormal pronucleus development and zygotic cleavage†.Rainsford SR, Tse K, Walters BW, Oh JN, Sumigray K, Lesch BJ, Smith ZD. Biol Reprod. 2026 Jan 20; 2026 Jan 20. PMID: 41556312.
Meristem fate: to terminate, or not?Lin CI, Irish VF. Front Plant Sci. 2025; 2026 Jan 19. PMID: 41635692.
B Lymphocyte Protein Factories produced by Hematopoietic Stem Cell Gene Editing.Hartweger H, Ruprecht C, Yao KH, Laffont P, Lima Dos Reis G, Zhou P, Hägglöf T, Binet L, Loewe M, Hong JP, Xiao T, Sefik E, Hernandez B, Gazumyan A, Jankovic M, Seaman MS, Costa G, Nelson SA, Clark J, Kanatani S, Wilson PC, Krammer F, Levashina EA, Julien JP, Wardemann H, Sinnis P, Stamatatos L, Flavell RA, Nussenzweig MC. bioRxiv. 2026 Jan 18; 2026 Jan 18. PMID: 41648379.
Integration of imaging-based and sequencing-based spatial omics mapping on the same tissue section via DBiTplus.Enninful A, Zhang Z, Klymyshyn D, Ingalls M, Yang M, Zong H, Bai Z, Farzad N, Su G, Baysoy A, Nam J, Lu Y, Bao S, Deng S, Zhang NR, Braubach O, Xu ML, Ma Z, Fan R. Nat Methods. 2026 Jan 15; 2026 Jan 15. PMID: 41540123.
The metabolic mood: Cholesterol homeostasis as a convergence point for depression risk.Choe MS, Park IH. Dev Cell. 2026 Jan 14. PMID: 41539289.
Multiple Myeloma Management in a Large Low- and Middle-Income Country: Lessons From India in Balancing Cost and Clinical Efficacy in Resource-Limited Settings.Roy PG, Gogia A, Anwar Z, Mukherjee S, Anwer F. JCO Oncol Pract. 2026 Jan 12; 2026 Jan 12. PMID: 41525508.
Tumor-initiating stem cells fine-tune the plasticity of neutrophils to sculpt a protective niche.Guo W, Luan J, Huang X, Leon D, Gang S, Nicholson B, Bertacchi B, Bolotin D, Lingen MW, Pearson AT, Izumchenko E, Rosenberg AJ, Agrawal N, Vokes EE, Punyawatthananukool S, Narumiya S, Gunzer M, Ballesteros I, Hidalgo A, Miao Y. Cancer Cell. 2026 Jan 12; 2025 Dec 4. PMID: 41349542.
Functional implications of polygenic risk for schizophrenia in human neurons.Michael Deans PJ, Retallick-Townsley KG, Li A, Seah C, Johnson J, Garcia Gonzalez J, Cao E, Schrode N, Yu A, Cartwright S, Voloudakis G, Zhang W, Wang M, Fullard JF, Girdhar K, Stahl E, Akbarian S, Zhang B, Roussos P, O'Reilly P, Huckins LM, Brennand KJ. Nat Commun. 2026 Jan 10; 2026 Jan 10. PMID: 41519853.
Nanoparticle-mediated bone regeneration: From molecular mechanisms to clinical translation.Wang S, Zhai SP, Wang B, Yan Y, Gong X, Liang Z, Medina G, Mak D, Caron J, Mak M. J Control Release. 2026 Jan 10; 2025 Nov 13. PMID: 41241012.
RIG-I RNA agonist activates immunostimulatory macrophages to enhance checkpoint immunotherapy for glioblastoma.Xu H, Lee S, Leser F, Fedorova O, Lu P, Song E, Touat M, Eichmann A, Iwasaki A, Pyle AM, Thomas JL. bioRxiv. 2026 Jan 8; 2026 Jan 8. PMID: 41542495.
A single BRCA2 BRC repeat supports viability while multiple repeats ensure resilience under stress.Mishra AP, Sahu S, Sengodan S, Moore G, Priya S, Oberoi N, Jensen JR, Southon E, Galloux M, Caylor D, Sullivan T, Burkett SS, Albaugh ME, Awasthi PP, Tomassoni Ardori F, Tessarollo L, Jensen RB, Sharan SK. bioRxiv. 2026 Jan 8; 2026 Jan 8. PMID: 41542399.
Generation of human pineal gland organoids with melatonin production for disease modeling.Kiral FR, Yang WS, Iyilikci O, Lu X, Kim J, Choe MS, Lo C, Zhong M, Kim KY, Jiang YH, Park IH. Cell Stem Cell. 2026 Jan 8; 2025 Dec 30. PMID: 41475351.
Outcomes of pPCL Diagnosed Using the IMWG 2021 Consensus Definition: A Retrospective Multicenter Analysis.Venkatesh P, Mansour R, Shatnawi Y, Jain A, Strouse C, Ahmed N, Mushtaq MU, Abdallah AO, Atrash S, Paul B. Cancers (Basel). 2026 Jan 5; 2026 Jan 5. PMID: 41514683.
ASTRO: Automated Spatial-Transcriptome whole RNA Output.Zhang D, Chu Z, Huo Y, Jiang Y, Chen Y, Bai Z, Fan R, Lu J, Gerstein M. Bioinformatics. 2026 Jan 3. PMID: 41495477.
Lamin A/C directs nucleosome-scale chromatin remodeling to define early lineage segregation in mammals.Sherrard A, Zhong L, Hoppe C, Krishna S, Youlten S, Boswell CW, Cross S, Sievers FE, Ardestani G, Sakkas D, Miao L, Smith ZD, Sozen B, Giraldez AJ. bioRxiv. 2026 Jan 2; 2026 Jan 2. PMID: 41502928.
Autologous cell therapy with CD133+ bone marrow-derived stem cells for Asherman Syndrome: a phase 1/2 trial.Santamaria X, Pardo-Figuerez M, González-Fernández J, Querol S, Rodríguez L, Valcárcel D, González C, Fernandez E, Amorós D, Robles M, Granados-Aparici S, Zuñiga S, Martinez F, Valbuena D, Gómez C, Herrero J, Aurell R, Torrent JJ, Vilella F, Volkov P, Raga F, Noguera R, Taylor HS, Simon C. Nat Commun. 2026 Jan 2; 2026 Jan 2. PMID: 41484096.
Shaping the intestine: The role of cell morphology and spatial dynamics in development.Wang Y, Wen Z, Sumigray K. Curr Top Dev Biol. 2026; 2025 Nov 14. PMID: 41856742.
Immunogenicity of induced pluripotent stem cell-derived smooth muscle cells results from a reduction in the expression of indoleamine 2,3 dioxygenase (IDO-1).Partridge K, Mehler VJ, Burns CJ, Pober JS, Moore ML. Regen Med. 2026 Jan; 2026 Feb 25. PMID: 41738185.