Recent Publications

A circadian checkpoint relocates neutrophils to minimize injury.Aroca-Crevillén A, Martín-Salamanca S, Torres LS, Crainiciuc G, Sicilia J, Peñaloza-Martínez E, Rosillo N, Molina-Moreno M, Adrover JM, Rubio-Ponce A, Vicanolo T, Liu X, Wichapong K, Núñez V, Balabanian K, Bachelerie F, Sancho D, Casanova-Acebes M, Ortiz-Pérez JT, Moro MÁ, Bueno H, Nicolaes GAF, Hidalgo A. J Exp Med. 2026 Feb 2; 2025 Dec 12. PMID: 41385080.
Impact of European LeukemiaNet-guided postremission therapy on outcomes of patients with AML from 2010 to 2022.Berdel AF, Ronnacker J, Wenge DV, Kolloch LJ, Berning P, Angenendt L, Brix TJ, Westermann A, Wethmar K, Kessler T, Kerkhoff A, Mesters RM, Reicherts C, Mikesch JH, Berdel WE, Lenz G, Schliemann C, Stelljes M. Blood Neoplasia. 2026 Feb; 2025 Nov 6. PMID: 41509995.
WHIM syndrome: from mechanism to targeted therapy - advances shaping clinical care.Miller RZ, Geier CB, Bledsoe JR, Pereira J, Walter JE. Curr Opin Allergy Clin Immunol. 2026 Feb 1; 2025 Dec 12. PMID: 41451822.
The Pediatric Clinician's Approach to Referring Children and Adolescents with Sickle Cell Disease for Potentially Curative Therapies.John TD, Krishnamurti L. Pediatr Clin North Am. 2026 Feb; 2025 Sep 26. PMID: 41207739.
tRNA m(1)A modification orchestrates STING translation in macrophages to enhance antitumor immunity and CAR-macrophage immunotherapy.Wang X, Wang X, Li H, Liu S, Lu Y, Chen H, Cai X, Su S, Li B, Liu R, Hu W, Zhu X, Zhang J, Ye Y, Li HB. Cell Mol Immunol. 2026 Jan 14; 2026 Jan 14. PMID: 41535541.
Multiple Myeloma Management in a Large Low- and Middle-Income Country: Lessons From India in Balancing Cost and Clinical Efficacy in Resource-Limited Settings.Roy PG, Gogia A, Anwar Z, Mukherjee S, Anwer F. JCO Oncol Pract. 2026 Jan 12; 2026 Jan 12. PMID: 41525508.
RBC Alloimmunization Impacts Pediatric Sickle Cell Disease Transplant Outcomes and Transfusion Burden: A STAR Registry Report.Inam Z, Stenger E, John TD, Liu K, Gillespie S, Shah R, Chellapandian D, Bhatia M, Chaudhury S, Eckrich MJ, Guilcher GMT, Hendrickson JE, Hulbert ML, Jaroscak JJ, Kasow KA, Camacho-Bydume C, Ngwube A, Olson TS, Rangarajan HG, Horan JT, Krishnamurti L, Shenoy S, Abraham A, Nickel RS. Am J Hematol. 2026 Jan 12; 2026 Jan 12. PMID: 41524608.
Training Tomorrow's Leaders in Cancer Immunology.Tan Y, Kim BJ, Mujal AM, Chen ACY, Weis AM, Bergaggio E, Micevic G, Xie H, Park JS, Hor JL, Papanicolaou M, Shobaki N, Domizi P, Delconte RB, Vendramin R, Hegde S, Han S, Su Y, Hacohen N. Cancer Immunol Res. 2026 Jan 12; 2026 Jan 12. PMID: 41524276.
Tumor-initiating stem cells fine-tune the plasticity of neutrophils to sculpt a protective niche.Guo W, Luan J, Huang X, Leon D, Gang S, Nicholson B, Bertacchi B, Bolotin D, Lingen MW, Pearson AT, Izumchenko E, Rosenberg AJ, Agrawal N, Vokes EE, Punyawatthananukool S, Narumiya S, Gunzer M, Ballesteros I, Hidalgo A, Miao Y. Cancer Cell. 2026 Jan 12; 2025 Dec 4. PMID: 41349542.
Functional implications of polygenic risk for schizophrenia in human neurons.Michael Deans PJ, Retallick-Townsley KG, Li A, Seah C, Johnson J, Garcia Gonzalez J, Cao E, Schrode N, Yu A, Cartwright S, Voloudakis G, Zhang W, Wang M, Fullard JF, Girdhar K, Stahl E, Akbarian S, Zhang B, Roussos P, O'Reilly P, Huckins LM, Brennand KJ. Nat Commun. 2026 Jan 10; 2026 Jan 10. PMID: 41519853.
Nanoparticle-mediated bone regeneration: From molecular mechanisms to clinical translation.Wang S, Zhai SP, Wang B, Yan Y, Gong X, Liang Z, Medina G, Mak D, Caron J, Mak M. J Control Release. 2026 Jan 10; 2025 Nov 13. PMID: 41241012.
Generation of human pineal gland organoids with melatonin production for disease modeling.Kiral FR, Yang WS, Iyilikci O, Lu X, Kim J, Choe MS, Lo C, Zhong M, Kim KY, Jiang YH, Park IH. Cell Stem Cell. 2026 Jan 8; 2025 Dec 30. PMID: 41475351.
ASTRO: Automated Spatial-Transcriptome whole RNA Output.Zhang D, Chu Z, Huo Y, Jiang Y, Chen Y, Bai Z, Fan R, Lu J, Gerstein M. Bioinformatics. 2026 Jan 6; 2026 Jan 6. PMID: 41495477.
Outcomes of pPCL Diagnosed Using the IMWG 2021 Consensus Definition: A Retrospective Multicenter Analysis.Venkatesh P, Mansour R, Shatnawi Y, Jain A, Strouse C, Ahmed N, Mushtaq MU, Abdallah AO, Atrash S, Paul B. Cancers (Basel). 2026 Jan 5; 2026 Jan 5. PMID: 41514683.
Sphingosine kinase 1 is integral for elastin deficiency-induced arterial hypermuscularization.Saito J, Dave JM, Gallardo-Vara E, Sadagopan N, Kabir I, Tellides G, Riemer RK, Urban Z, Spiegel S, Hla T, Greif DM. Nat Cardiovasc Res. 2026 Jan 5; 2026 Jan 5. PMID: 41492020.
Lamin A/C directs nucleosome-scale chromatin remodeling to define early lineage segregation in mammals.Sherrard A, Zhong L, Hoppe C, Krishna S, Youlten S, Boswell CW, Cross S, Sievers FE, Ardestani G, Sakkas D, Miao L, Smith ZD, Sozen B, Giraldez AJ. bioRxiv. 2026 Jan 2; 2026 Jan 2. PMID: 41502928.
Autologous cell therapy with CD133+ bone marrow-derived stem cells for Asherman Syndrome: a phase 1/2 trial.Santamaria X, Pardo-Figuerez M, González-Fernández J, Querol S, Rodríguez L, Valcárcel D, González C, Fernandez E, Amorós D, Robles M, Granados-Aparici S, Zuñiga S, Martinez F, Valbuena D, Gómez C, Herrero J, Aurell R, Torrent JJ, Vilella F, Volkov P, Raga F, Noguera R, Taylor HS, Simon C. Nat Commun. 2026 Jan 2; 2026 Jan 2. PMID: 41484096.
Mesenchymal stem cells reverse disease-specific abnormalities in nociceptive regions of the brain.Fukushi R, Sasaki M, Obara H, Kurihara K, Hirota R, Morita T, Teramoto A, Yamashita T, Tan AM, Waxman SG, Kocsis JD, Honmou O. Brain Commun. 2026; 2025 Dec 15. PMID: 41509715.
Prevalence and patient-level factors associated with common antibiotic allergy labels among patients undergoing hematopoietic stem cell transplants: a cross-sectional study.Belmont AP, Reynolds J, Stone CA Jr, Dziura J, Malinis M, Phillips EJ, Sarpong D, Seropian S, Edelman EJ. J Allergy Clin Immunol Pract. 2026 Jan; 2025 Oct 28. PMID: 41161669.
hiPSC-Derived Astrocytes From Individuals With Schizophrenia Induce a Dystrophic Phenotype in Microglial-Like Cells.Cardozo PL, Lee CY, Lacerda JPS, Fahel JS, Trindade P, Vitória G, Chicaybam L, Cordeiro RC, de Faria IJS, Silva NC, Todjro YMH, Maciel JCDP, Bonamino MH, Vieira LB, Cruz BF, Nicolato R, Brennand KJ, Rehen SK, Ribeiro FM. Glia. 2026 Jan; 2025 Sep 19. PMID: 40970468.
High-Deductible Health Plans and Out-of-Pocket Health Care Costs Among Younger Patients With Multiple Myeloma.Fiala MA, Ji M, Slade M, Huber JH, Shih YH, Wang M, Colditz GA, Wang SY, Vij R, Chang SH. JCO Oncol Pract. 2026 Jan; 2025 May 12. PMID: 40354593.
Pertpy: an end-to-end framework for perturbation analysis.Heumos L, Ji Y, May L, Green TD, Peidli S, Zhang X, Wu X, Ostner J, Schumacher A, Hrovatin K, Müller M, Chong F, Sturm G, Tejada A, Dann E, Dong M, Pinto G, Bahrami M, Gold I, Rybakov S, Namsaraeva A, Moinfar AA, Zheng Z, Roellin E, Mekki I, Sander C, Lotfollahi M, Schiller HB, Theis FJ. Nat Methods. 2025 Dec 31; 2025 Dec 31. PMID: 41476114.
Mutant p53 promotes clonal hematopoiesis through generating a chronic inflammatory microenvironment.Chen S, Barajas S, Vemula S, Yang Y, Simpson E, Gao H, Li R, Behzadnia F, Nabinger SC, Schmitz DA, Chen H, Cai W, Xiao S, Luo R, Amin MA, Capitano ML, Ropa JP, Fahey A, Zhou S, Mays TM, Sotelo M, Pan H, Hu SK, Veranga S, Ali M, Shumilina M, Kapur R, Ren K, Jia Y, Liu H, Khan I, Abaza Y, Altman JK, Eklund EA, Godley LA, Zhang CR, Ji P, Masters SL, Croker BA, Boswell HS, Sandusky GE, Gao Z, Mayo LD, Savage SA, Halene S, Dou Y, Platanias LC, Sukhanova M, Liu Y, Abdel-Wahab O, Liu Y. J Clin Invest. 2025 Dec 30; 2025 Dec 30. PMID: 41468163.
T follicular helper cells transiently unlock a plasticity state in germinal centre B cells during the humoral immune response.Scourzic L, Izzo F, Teater M, Polyzos AP, Cucereavii L, Chin CR, Papin A, Pinto HB, Mlynarczyk C, Tsialta I, Xia M, Lidoski A, Myers RM, Israel EM, Venturutti L, Mackay SP, Hoehn KB, Skoultchi AI, Béguelin W, Stadtfeld M, Chen Z, Landau DA, Melnick AM, Apostolou E. Nat Cell Biol. 2025 Dec 29; 2025 Dec 29. PMID: 41466145.
Mast cell extracellular granules are bioactive condensates driven by heparin and polyamine.Xiong Y, Tomares DT, Guo J, Sato K, Zeng L, Tian Y, Su M, Albis A, Pant A, Pappu RV, Su X. bioRxiv. 2025 Dec 26; 2025 Dec 26. PMID: 41497591.
Reprogramming Stars #26: Understanding the Reprogramming Privilege-An Interview with Dr. Shangqin Guo.Guo S, Lopes M, Pereira CF. Cell Reprogram. 2025 Dec 17; 2025 Dec 17. PMID: 41467887.
Rethinking the Microenvironment's Role in Chemical-Induced Malignancy.Bisson WH, Currie RA, Lim EL, Mlynarczyk C, Tokar EJ, Colacci A, Colacino JA. Toxicol Sci. 2025 Dec 17; 2025 Dec 17. PMID: 41405843.
Editorial: Exploring immune-stromal cell dynamics: pathways and therapeutic implications.Ryu S, Gauld SB, Staron MM, Odell ID, Cash JL, Radstake TR. Front Immunol. 2025; 2025 Dec 15. PMID: 41488651.
Global burden of lower respiratory infections and aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.Lancet Infect Dis. 2025 Dec 15; 2025 Dec 15. PMID: 41412141.
3D bioprinting of cell-laden constructs: technologies, bioink design, and biomedical applications.Xing Q, Liu Y, Thomas JL, Zhang W, Riaz M, Mak M, Qyang Y. Biomed Mater. 2025 Dec 15; 2025 Dec 15. PMID: 41330064.
Functional specialization of the calvarial bone marrow.Koh BI, Adams R. Physiology (Bethesda). 2025 Dec 13; 2025 Dec 13. PMID: 41389063.
Double stranded RNA sensing is silenced during early embryonic development.Witteveldt J, Liu Z, Ariza-Cosano A, Ramirez C, Walters JL, Marchante PG, Maas L, Friman ET, Ivens A, Tebaldi T, Heras SR, Marks H, Macias S. Nat Commun. 2025 Dec 11; 2025 Dec 11. PMID: 41381491.
The Role of Platelet-Rich Plasma in Treating Osteochondral Lesions of the Talus: A Systematic Review of Clinical and Preclinical Evidence.Halayqeh S, Conroy B, Boggiano V, Patel S, Gianakos AL. JBJS Rev. 2025 Dec 1; 2025 Dec 11. PMID: 41379984.
Uncovering the role of LINE-1 in the evolution of lung adenocarcinoma.Zhang T, Zhao W, Wirth C, Díaz-Gay M, Yin J, Cecati M, Marchegiani F, Hoang PH, Leduc C, Baine MK, Travis WD, Sholl LM, Joubert P, Sang J, McElderry JP, Antony M, Klein A, Khandekar A, Hartman C, Rosenbaum J, Colón-Matos FJ, Miraftab M, Saha M, Lee OW, Jones KM, Caporaso NE, Wong MP, Leung KC, Hsiung CA, Chen CY, Edell ES, Santamaría JM, Schabath MB, Yendamuri SS, Manczuk M, Lissowska J, Świątkowska B, Mukeria A, Shangina O, Zaridze D, Holcatova I, Mates D, Milosavljevic S, Savic M, Bossé Y, Rothberg BEG, Christiani DC, Gaborieau V, Brennan P, Liu G, Hofman P, Homer R, Yang SR, Pesatori AC, Consonni D, Yang L, Zhu B, Shi J, Brown K, Rothman N, Chanock SJ, Alexandrov LB, Choi J, Cardelli M, Lan Q, Nowak MA, Wedge DC, Landi MT. Nature. 2025 Dec 10; 2025 Dec 10. PMID: 41372401.
Gene-corrected regulatory T cell therapy for IL2RA deficiency.Ha AS, Kalter N, Rosenberg M, Acevedo LA, Liang B, Liu W, Paruthiyil S, Sinha M, Vu A, Nguyen V, Qi Z, Krishnappa N, Shu J, Yu J, Catanzaro J, Bluestone JA, Tang Q, Urnov FD, Marson A, Hendel A, Herold KC, Shy BR, Esensten JH. Mol Ther. 2025 Dec 9; 2025 Dec 9. PMID: 41376159.
Overcoming the eIF2α Brake in Human Cell-Derived Translation Systems.Aleksashin NA, Shelke RR, Yin T, Cate JHD. bioRxiv. 2025 Dec 7; 2025 Dec 7. PMID: 41497621.
Pre-existing and early cellular immune factors correlate with functionally complete protection against primary controlled human SARS-CoV-2 infection.Wagstaffe HR, Thwaites RS, Sidhu JK, Lindeboom RGH, Kretschmer L, Worlock KB, Dratva LM, Huang A, Ascough S, Papargyris L, McKendry R, Collins AM, Xu J, Lemm NM, Killingley B, Kalinova M, Mann A, Catchpole A, Swadling L, Tsang JS, Maini MK, Noursadeghi M, Nikolić MZ, Teichmann SA, Openshaw PJM, Chiu C. Nat Commun. 2025 Dec 7; 2025 Dec 7. PMID: 41354730.
The global epidemiology of acute myeloid leukaemia.El Chaer F, Bewersdorf JP, Stahl M, Zeidan AM. Nat Rev Clin Oncol. 2026 Feb; 2025 Dec 5. PMID: 41350446.
Generation and characterization of an ovine cell line derived from peripheral blood and its potential use in the study of livestock and zoonotic viral infections.Moreno S, Sanjurjo-Rodríguez C, Rodríguez-Fernández S, Jiménez-Cabello L, Calvo-Pinilla E, Nogales A, Marín-López A, Ortego J, Brun A, Díaz-Prado S, Lorenzo G. Virol J. 2025 Dec 2; 2025 Dec 2. PMID: 41331844.
Rroid2 regulates effector-to-memory CD8(+) T cell differentiation during infection in vivo.Erber J, Stecher C, Plajer V, Braun N, Mallard W, Goff LA, Barozzi I, Mohr T, Rinn JL, Flavell RA, Herndler-Brandstetter D. Proc Natl Acad Sci U S A. 2025 Dec 2; 2025 Nov 24. PMID: 41284876.
Global, Regional, and National Burden of Cardiovascular Diseases and Risk Factors in 204 Countries and Territories, 1990-2023.J Am Coll Cardiol. 2025 Dec 2; 2025 Sep 24. PMID: 40990886.
Functional Spinal Unit Approach for Orthobiologic Injections for Low Back Pain.Navani A, Vardhan S, Aggarwal A, Navani R, Lana JF, Diwan SA. Pain Physician. 2025 Dec. PMID: 41481872.
Establishment, Characterization, and Cryopreservation of Feather Follicle Fibroblast Lines From Hyacinth Macaw (Anodorhynchus hyacinthinus).Nogueira IPM, Teixeira-Santos RC, Cotta GC, Valente W, de Coimbra JLP, Ferreira HAS, Guimarães PPG, Santos AK, Fontoura FM, de Andrade Ramalho KR, Guedes NMR, Lacerda SMDSN. Cell Biol Int. 2025 Dec; 2025 Oct 2. PMID: 41036675.
Allogeneic haematopoietic cell transplantation in advanced systemic mastocytosis in the new era: A CIBMTR study.Ustun C, Zhang MJ, Peterson A, Baek A, Agha M, Alkhateeb H, Chhabra S, Coltoff A, de Lima M, Gandhi A, Ho V, Kassim A, Lin A, Gowda L, Borthakur G, DeAngelo DJ, McGuirk J, Mensah F, Nadiminti KV, Nishihori T, Pantin J, Trunk A, Uberti J, Marcucci G, Gotlib J, Akin C, Hamadani M, Pullarkat V, Valent P, Grunwald M, Juckett M, Oran B, Saber W, Burns LJ. Br J Haematol. 2025 Dec; 2025 Sep 22. PMID: 40983528.
The global, regional, and national burden attributable to low bone mineral density, 1990-2020: an analysis of a modifiable risk factor from the Global Burden of Disease Study 2021.Lancet Rheumatol. 2025 Dec; 2025 Sep 16. PMID: 40972625.
Decreased cholinergic neuronal firing in a mouse model of temporal lobe seizures with impaired consciousness.Liu S, Paszkowski P, Qu J, Sieu LA, Liu J, Valcarce-Aspegren M, Khan W, McGill S, Lee D, Duque A, Blumenfeld H. Epilepsia. 2025 Dec; 2025 Sep 16. PMID: 40956639.
RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53(R249S) Mutation and is a Potential Therapeutic Target.Wu Z, Wang Z, Zheng D, Zheng Y, Jiang Z, Lv J, Zhu Y, Jia H, Duan Z, Yuan T, Wu Q, Long Y, Lin S, Yao Y, Carson G, Thiery JP, Man K, Li P. Adv Sci (Weinh). 2025 Dec; 2025 Sep 8. PMID: 40919676.
Author Correction: Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy.Zhang F, Chow RD, He E, Dong C, Xin S, Mirza D, Feng Y, Tian X, Verma N, Majety M, Zhang Y, Wang G, Chen S. Nat Biotechnol. 2025 Dec. PMID: 39901026.
Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy.Zhang F, Chow RD, He E, Dong C, Xin S, Mirza D, Feng Y, Tian X, Verma N, Majety M, Zhang Y, Wang G, Chen S. Nat Biotechnol. 2025 Dec; 2025 Jan 16. PMID: 39820813.
Calcineurin inhibitor and eltrombopag combination for acquired aplastic anemia: results from a large national database.Stempel JM, Wang R, Lee AI, Zeidan AM, Ma X, Podoltsev NA. Ther Adv Hematol. 2025; 2025 Nov 30. PMID: 41333634.
3D genetic architecture of schizophrenia risk across three neuronal subtypes.Powell SK, Liao W, Ghorbani S, Rigat R, O'Shea C, Kammourh S, Elahi R, Infante D, Deans PJM, Le DJ, Agarwal P, Qiang Seow W, Balafkan N, Wang KC, Akbarian S, Brennand KJ. Mol Psychiatry. 2025 Nov 28; 2025 Nov 28. PMID: 41310180.
Exploring early add-on celecoxib treatment in OCD: Results from a preliminary randomized, double-blind, placebo-controlled trial.Singh S, Nischal A, Nischal A, Singh SK, Singh V, Tripathi A. J Psychopharmacol. 2025 Nov 27; 2025 Nov 27. PMID: 41310954.
Human plasma proteomic profile of clonal hematopoiesis.Yu Z, Vromman A, Nguyen NQH, Schuermans A, Li L, Rentz T, Nakao T, Vellarikkal SK, Uddin MM, Niroula A, Griffin G, Honigberg MC, Lin AE, Gibson CJ, Katz DH, Tahir UA, Fang S, Dron JS, Pan M, Haidermota S, Ganesh S, Antoine T, Weinstock J, Austin TR, Vasan RS, Peloso GM, Hornsby W, Ganz P, Manson JE, Haring B, Kooperberg C, Reiner AP, Bis JC, Psaty BM, Min YI, Correa A, Lange LA, Post WS, Rotter JI, Rich SS, Wilson JG, Ebert BL, Yu B, Ballantyne CM, Coresh J, Sankaran VG, Bick AG, Jaiswal S, Gerszten RE, Libby P, Gupta RM, Natarajan P. Nat Commun. 2025 Nov 27; 2025 Nov 27. PMID: 41309676.
SPACEc: a streamlined, interactive Python workflow for multiplexed image processing and analysis.Tan Y, Kempchen TN, Becker M, Haist M, Feyaerts D, Liu J, Toma M, Xiao Y, Su G, Rech AJ, Hölzel M, Fan R, Hickey JW, Nolan GP. Nat Commun. 2025 Nov 27; 2025 Nov 27. PMID: 41309581.
Towards insulin independence in type 1 diabetes: Prospects for prevention and cure.Sydney GI, Perdigoto AL, Herold KC. PLoS Med. 2025 Nov; 2025 Nov 25. PMID: 41289263.
Noradrenergic control of bone marrow and thymus by AgRP neurons is impaired in experimental multiple sclerosis.Vigo T, Mariani MC, Bason C, Ferrara G, Cornacchia E, Francia S, Potenzieri A, Ricci E, Grasselli G, Zoppoli G, Cirmena G, Ferrando L, Procaccini C, Russo C, Altosole T, Cerutti E, Capodivento G, Bottero M, Liberale L, Scotto M, Laroni A, Inglese M, Sulis Sato S, Catarino J, Centonze D, Matarese G, Benfenati F, Horvath TL, Kerlero de Rosbo N, Uccelli A. Cell Rep. 2025 Nov 25; 2025 Nov 12. PMID: 41231671.
In vivo differentiation of embryonic cells devoid of key reprogramming factors.Youlten SE, Miao L, Hoppe C, Boswell CW, Musaev D, Abdelmessih M, Olowookere D, Weiss LA, Krishnaswamy S, Giraldez AJ, Tornini VA. Cell Rep. 2025 Nov 25; 2025 Oct 30. PMID: 41171758.
Precision Chemistry in Precision Diagnostics.Zhong W, Liu Y, Fan R. Precis Chem. 2025 Nov 24; 2025 Oct 29. PMID: 41312084.
Advancements in Cellular Therapeutics in Corneal Diseases.Woo E, Henick D, Tahvildari M. Cells. 2025 Nov 21; 2025 Nov 21. PMID: 41369327.
Haplotype editing with CRISPR-Cas9 as a therapeutic approach for dominant-negative missense mutations in NEFL.Dua PH, Simon BMJ, Marley CBE, Feliciano CM, Watry HL, Cowan QT, Steury D, Abraham A, Gilbertson EN, Ramey GD, Capra JA, Conklin BR, Judge LM. Mol Ther. 2025 Nov 19; 2025 Nov 19. PMID: 41267399.
Hippocampal Development and Epilepsy: Insights from Organoid Models.Joo J, Yang WS, Koh HJ. Brain Sci. 2025 Nov 16; 2025 Nov 16. PMID: 41300237.
Brain-wide Genome Editing via STEP-RNPs for Treatment of Angelman Syndrome.Lu X, Xie Y, Bao Y, Yu J, Wang Z, Fan J, Sheu WC, Long G, Tu Z, Tong J, Manquen G, Li Y, Katta V, Chow R, Chen B, Meng Z, Ma YH, Qiu C, Chen S, Tsai SQ, De Kumar B, Hendry CE, Jiang YH, Zhou J. bioRxiv. 2025 Nov 14; 2025 Nov 14. PMID: 41292800.
Adenovirus E4ORF1 activates isoform-specific phosphatidylinositol 3-kinase signaling in human endothelial cells.Geng F, Kobayashi M, Lin Y, Gomez-Salinero JM, Romano D, Kanyo J, Geng J, Liu Y, Ginsberg M, Shieh JH, Chen K, Lam TT, Rafii A, Rabbany SY, Lis R, Rafii S. J Biol Chem. 2025 Nov 13; 2025 Nov 13. PMID: 41241101.
Early time to relapse as a survival prognosticator in mature T-cell/NK-cell lymphomas: results from the PETAL Consortium.Sorial MN, Malpica L, Chiattone CS, Julia E, Bachy E, Barta SK, Stuver RN, Jacobsen ED, Federico M, Jain H Dr, Prince HM, Foss FM, Zinzani PL, Okatani T, Kim WSS, Verburgh E, Al-Mansour M, Cabrera ME, Bhagat G, Shah D, Shen C, Jain S. Blood. 2025 Nov 12; 2025 Nov 12. PMID: 41347825.
Cell-type-resolved NRXN1 isoforms across human brain tissues and hiPSC organoids.Cao L, Fan Y, Ghorbani S, Mariani J, Zhang Y, Fernando MB, Bendl J, Fullard J, Ramos SI, Mead EA, Deikus G, Beaumont KG, Sebra R, Tsankova N, Roussos P, Brennand KJ, Fang G. bioRxiv. 2025 Nov 11; 2025 Nov 11. PMID: 41293024.
Author Correction: Tissue-scale coordination of cellular behaviour promotes epidermal wound repair in live mice.Park S, Gonzalez DG, Guirao B, Boucher JD, Cockburn K, Marsh ED, Mesa KR, Brown S, Rompolas P, Haberman AM, Bellaïche Y, Greco V. Nat Cell Biol. 2025 Nov 10; 2025 Nov 10. PMID: 41214304.
Tailoring Intensity: A Perspective on Thiotepa, Busulfan, and Fludarabine (TBF) Conditioning for Acute Leukemias and Myeloproliferative Neoplasms.Abdel Rahman Z, Mansour R, Kharfan-Dabaja M, Ma'koseh M, Muhanna Z, Saad A, Hanbali A, El Fakih R, Aljurf M. Transplant Cell Ther. 2025 Nov 8; 2025 Nov 8. PMID: 41213501.
Advances in Cell-Mediated Drug Delivery for Dermatologic Diseases: Mechanisms and Current Applications.Shqair L, Draw I, Maya T, Bunick CG, Akbarialiabad H, Schlesinger T, Damiani G, Ghannoum M, Grada A. Pharmaceutics. 2025 Nov 7; 2025 Nov 7. PMID: 41304776.
Recessive genomic and phenotypic variation in consanguineous families with cerebral palsy.Bisarad P, Wang YC, Skidmore PT, Galaz-Montoya CI, Lewis SA, Alhaddad B, Kong N, Julian D, Magee H, Kruer TN, Xie Y, Zheng W, Li B, Rajabpour FV, Liu J, Revanur A, Bakur K, Firouzabadi SG, Sharbatkhori S, Tafakhori A, Taghiabadi E, Nezaminargabad E, Vosoogh S, Jamshidi J, Arefnia S, Hosseini SA, Khajehmirzaei A, Jamali F, Ahmadifard A, Khodadadi H, Daneshmand P, Bohlega S, Maddirevula S, Nadeef SS, Hashem MO, Salih MA, Mohmed IN, Sticht H, Morias SP, Damásio J, Santos M, Loureiro JL, Rodrigues R, Stevanin G, Benkirane M, Dauriat B, Head N, Baptista J, Shahhosseini S, Mohammad F, Zhao H, Padilla-Lopez S, Alkuraya F, Bakhtiari S, Kruer MC, Jin SC, Darvish H. medRxiv. 2025 Nov 6; 2025 Nov 6. PMID: 41282771.
MYOD represses gene expression from non-E-box motifs.Nicoletti C, Massenet J, Pintado-Urbanc AP, Connor LJ, Nicolau M, Sundar S, Xu M, Schmitt A, Zhang W, Fang Z, Chan TCI, Wang YX, Tapscott SJ, Cheung TH, Simon MD, Caputo L, Puri PL. Genes Dev. 2025 Nov 3; 2025 Nov 3. PMID: 40769720.
Human-Induced Pluripotent Stem Cell Models for Amyloid Cardiomyopathy: From Mechanistic Insights to Therapeutic Discovery.Liu Y, Riaz M. J Cardiovasc Dev Dis. 2025 Nov 2; 2025 Nov 2. PMID: 41295360.
Endometrial Injury and Its Rescue by Mesenchymal Stem Cells Is Dependent on Estrous Cycle Phase.Mamillapalli R, Liu Y, Zhou Y, Tal R, Taylor HS. J Cell Mol Med. 2025 Nov. PMID: 41294044.
Altered Epithelial-Mesenchymal Progenitor States Lead to Matrix Deposition, Tissue Inflammation, and Transitional Epithelial State in Congenital Diaphragmatic Hernia.Rivero R, Edelstein S, Haynes C, Mizoguchi S, Wang N, Saltzman M, Stitelman DH, Raredon MSB. Fetal Pediatr Pathol. 2025 Nov-Dec; 2025 Nov 17. PMID: 41246903.
Spatial dynamics of brain development and neuroinflammation.Zhang D, Rubio Rodríguez-Kirby LA, Lin Y, Wang W, Song M, Wang L, Wang L, Kanatani S, Jimenez-Beristain T, Dang Y, Zhong M, Kukanja P, Bao S, Wang S, Chen XL, Gao F, Wang D, Xu H, Ma C, Lou X, Liu Y, Chen J, Sestan N, Uhlén P, Kriegstein A, Zhao H, Castelo-Branco G, Fan R. Nature. 2025 Nov; 2025 Nov 5. PMID: 41193846.
The new frontier in understanding human and mammalian brain development.Nowakowski TJ, Nano PR, Matho KS, Chen X, Corrigan EK, Ding W, Gao Y, Heffel M, Jayakumar J, Kaplan HS, Kronman FN, Kovner R, Mannens CCA, Song M, Steyert MR, Venkatesan S, Wallace JL, Wang L, Werner JM, Zhang D, Yuan G, Zuo G, Ament SA, Colantuoni C, Dulac C, Fan R, Gillis J, Kriegstein AR, Krienen FM, Kim Y, Linnarsson S, Mitra PP, Pollen AA, Sestan N, Tward DJ, van Velthoven CTJ, Yao Z, Bhaduri A, Zeng H. Nature. 2025 Nov; 2025 Nov 5. PMID: 41193845.
Perspectives of potential haematopoietic stem-cell donors on education TikToks.Jian YC, Park B, Vijenthira S, Fingrut WB. Lancet Haematol. 2025 Nov. PMID: 41193115.
Shared responsibility and global progress in stem cell research.Greco V. Nat Med. 2025 Nov. PMID: 41145792.
CFTR High Expresser BEST4(+) cells are pH-sensing neuropod cells: new implications for intestinal physiology and cystic fibrosis disease.Dos Reis DC, Jin J, Santos A, Dastoor P, Muiler C, Zagoren E, Donnelley M, Parsons D, Cmielewski P, Reyne N, McCarron A, Smith Z, Sumigray K, Ameen NA. Am J Physiol Cell Physiol. 2025 Nov 1; 2025 Sep 26. PMID: 41005986.
SUV39H1 Regulates KLF4 and Chromatin Remodeling in Smooth Muscle Cell Phenotypic Plasticity.Chatterjee P, Chakraborty R, Sizer AJ, O'Brien BJ, Xu P, Hwa JM, Xie Y, Yan Q, Hwa J, Martin KA. Arterioscler Thromb Vasc Biol. 2025 Nov; 2025 Aug 21. PMID: 40836920.
Use of AMD3100 for bone marrow-derived mesenchymal stem cell mobilization in the treatment of murine Asherman's syndrome.Flores VA, Delis PA, Mamillapalli R, Taylor HS. F S Sci. 2025 Nov; 2025 Aug 14. PMID: 40818715.
Checkpoint inhibitor benefit in perioperative gastro-esophageal cancer: A meta-analysis of phase III trials.Zhao JJ, Yi Ng KY, Sundar R, Klempner SJ. Cancer Treat Rev. 2025 Nov; 2025 Aug 6. PMID: 40779895.
TMBIM4 affects left-right patterning via pluripotency exit during gastrulation.Diab NS, Kostiuk V, Tyan L, Mis E, Zenisek D, Khokha MK. Dev Biol. 2025 Nov; 2025 Jul 29. PMID: 40744297.
Exosomes in Dermatology: A Comprehensive Review of Current Applications, Clinical Evidence, and Future Directions.Nahm WJ, Nikas C, Goldust M, Horneck N, Cervantes JA, Burshtein J, Tsoukas M. Int J Dermatol. 2025 Nov; 2025 Jun 18. PMID: 40533901.
Improved outcomes of acute lymphoblastic leukemia after allogeneic blood or marrow transplantation with highdose post-transplantation cyclophosphamide in the era of more effective pre-transplant therapy.Webster JA, Reed M, Tsai HL, Imus PH, Smith DB, Ambinder AJ, Levis MJ, DeZern AE, Prince GT, Jain T, Bolaños-Meade J, Gondek LP, Ghiaur G, Dalton WB, Karantanos T, Paul S, Fuchs EJ, Sterling C, Swinnen LJ, Wagner-Johnston N, Ambinder RF, Gocke CB, Ali SA, Huff CA, Luznik L, Varadhan R, Jones RJ, Gojo I. Haematologica. 2025 Nov 1; 2025 May 8. PMID: 40336316.
No clear benefit of cellular therapy consolidation for patients achieving remission after post-HCT AML relapse.Murdock HM, Kim HT, Maurer K, Kelkar AH, Shapiro RM, Gooptu M, Romee R, Nageshwar PK, Garrity HM, Shimony S, Luskin MR, Winer ES, Vedula RS, Stahl MF, Chen EC, Volpe VO, Garcia JS, Wadleigh M, DeAngelo DJ, Stone RM, Wu CJ, Cutler CS, Koreth J, Ritz J, Antin JH, Ho VT, Nikiforow S, Soiffer RJ. Blood Adv. 2025 Oct 31; 2025 Oct 31. PMID: 41172235.
Loss of D expression associated with hematologic disease progression: a case report and review of the literature.Yurtsever N, Carmichael G, Li P, Wen JD, Chai H, Diadamo A, Denomme G, Tormey C. Immunohematology. 2025 Sep 1; 2025 Oct 31. PMID: 41168989.
Spatial profiling of patient-matched HER2 positive gastric cancer reveals resistance mechanisms to targeted therapy.Sheng T, Sundar R, Srivastava S, Ong X, Tay ST, Ma H, Uchihara T, Lian BSX, Hagihara T, Kong MS, Xu C, Ho SWT, Huang KK, Tan ALK, Ng MSW, Toh J, Ng CSY, Nasca V, Pircher CC, Randon G, Giordano S, Corso S, Lum JHY, Zhao JJ, Teh M, So JBY, Sabella G, Prabhakar S, Lee J, Ng MCH, Shitara K, Gasparello J, Fassan M, Pietrantonio F, Tan P. Gut. 2025 Oct 30; 2025 Oct 30. PMID: 41167802.
Multiscale proteomic modeling reveals protein networks driving Alzheimer's disease pathogenesis.Wang E, Yu K, Cao J, Wang M, Katsel P, Song WM, Wang Z, Li Y, Wang X, Wang Q, Xu P, Yu G, Zhu L, Geng J, Habibi P, Qian L, Tuck T, Li A, Tcw J, Roussos P, Brennand KJ, Haroutunian V, Johnson ECB, Seyfried NT, Levey AI, Bennett DA, Peng J, Cai D, Zhang B. Cell. 2025 Oct 30; 2025 Sep 25. PMID: 41005309.
Examination of Germline and Somatic Intercellular Bridges in Hydra vulgaris Reveals Insights into the Evolutionarily Conserved Mechanism of Intercellular Bridge Formation.Price KL, Tharakan DM, Salvenmoser W, Ayers K, Mah J, Dunn C, Hobmayer B, Cooley L. Mol Biol Evol. 2025 Oct 29. PMID: 41032677.
Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors.Karatepe K, Mafra de Faria B, Zhang J, Chen X, Pinto H, Fyodorov D, Sefik E, Willcockson MA, Flavell RA, Skoultchi AI, Guo S. Proc Natl Acad Sci U S A. 2025 Oct 28; 2025 Oct 21. PMID: 41118213.
Radiofrequency regulates the BET-mediated pathways in radial glia differentiation in human cortical development.Cakir B, Tanaka Y, Choe MS, Kiral FR, Kim J, Micali N, Kang YJ, Dharmadhikari B, Patterson B, Yang WS, Cho Y, Xiang Y, Zhong M, Lee SH, Patra P, Rakic P, Park IH. Cell Rep. 2025 Oct 28; 2025 Sep 24. PMID: 40997800.
Cost-effectiveness of upfront vs delayed allogeneic hematopoietic stem cell transplant for intermediate risk AML.Alhajahjeh A, Patel KK, Podoltsev NA, Kewan T, Stempel JM, Mendez L, Seropian S, Gowda L, Huntington SF, Stahl M, Zeidan AM, Goshua G, Bewersdorf JP. Blood Adv. 2025 Oct 28. PMID: 40720773.
CRISPR-engineered deletion of POGZ alters transcription factor binding at promoters of genes involved in synaptic signaling.Moyses-Oliveira M, Liu Y, Erdin S, Gao D, Bhavsar R, Mohajeri K, O'Keefe K, Boone PM, Xavier G, Liao C, Li A, Yadav R, Salani M, Lucente D, Currall B, de Esch CEF, Tai DJC, Ruderfer D, Brennand KJ, Gusella JF, Talkowski ME. bioRxiv. 2025 Oct 27; 2025 Oct 27. PMID: 41279137.
In Silico Post-screening of Anti-polymerization Agents to Treat Sickle Cell Disease.Qian Y, Daryakenari NA, Hallow M, Lu L, Buffet PA, Dao M, Li H, Karniadakis GE. bioRxiv. 2025 Oct 26; 2025 Oct 26. PMID: 41279536.
CRS or ICANS Are Rare Beyond 2 Weeks After Lisocabtagene Maraleucel Infusion: Data From Clinical Trials and the Real-World Setting.Hunter BD, Lunning M, Shadman M, Ahmed S, Abramson JS, Perales MA, Ahmed N, Mirza AS, Isufi I, Frigault MJ, Crombie JL, Miklos DB, Vasconcelos A, Crotta A, Bernasconi D, Roy D, Bleickardt E, Pasquini MC, Kamdar M. Transplant Cell Ther. 2025 Oct 24; 2025 Oct 24. PMID: 41235976.
IGFBP2 Mediates Human iPSC-Cardiomyocyte Proliferation in a Cellular Contact-Dependent Manner.Lee S, Heinrich P, Lee D, Kang Y, Robinson HR, Humphrey SJ, Yun J, Goodyer WR, Buikema JW, Paik DT, Galdos FX, Kim B, Belbachir N, Min S, Cho SW, Lee J, Moretti A, Wu JC, Hudson JE, Wu SM. Circ Res. 2025 Oct 24; 2025 Oct 1. PMID: 41031396.
Consensus meta-analysis of genome-wide association studies for Alzheimer's disease and related dementia.medRxiv. 2025 Oct 23; 2025 Oct 23. PMID: 41282675.
Epigenetic priming promotes tyrosine kinase inhibitor resistance and oncogene amplification.Starble RM, Sun EG, Gbyli R, Radda J, Lu J, Jensen TB, Sun N, Khudaverdyan N, Zhao T, Hu B, Melnick MA, Zhao S, Roper N, Wang GG, Tackett AJ, Wang Y, Song J, Politi K, Wang S, Xiao AZ. Nat Struct Mol Biol. 2025 Oct 23; 2025 Oct 23. PMID: 41131337.
Ancient origin of an urban underground mosquito.Haba Y, Korlević P, McAlister E, Lawniczak MKN, Schumer M, Rose NH, McBride CS, Aardema ML, Afonso MO, Agramonte NM, Albright J, Alho AM, Almeida APG, Alout H, Alten B, Altinli M, Amara Korba R, Andreadis SS, Anghel V, Arich S, Arsenault-Benoit A, Atyame C, Aubry F, Avila FW, Ayala D, Azrag RS, Babayan L, Bear A, Becker N, Bega AG, Bejarano S, Ben-Avi I, Benoit JB, Boubidi SC, Bradshaw WE, Bravo-Barriga D, Bueno-Marí R, Bušić N, Čabanová V, Cabeje B, Caputo B, Cardo MV, Carpenter S, Carreton E, Chouaïbou MS, Christian M, Coetzee M, Conner WR, Cornel A, Culverwell CL, Cupina AI, De Wolf K, Deblauwe I, Deegan B, Delacour-Estrella S, Della Torre A, Diaz D, Dool SE, Dos Anjos VL, Dugassa S, Ebrahimi B, Eisa SYM, Elissa N, Fallatah SAB, Faraji A, Fedorova MV, Ferrill E, Fonseca DM, Foss KA, Foxi C, França CM, Fricker SR, Fritz ML, Frontera E, Fuehrer HP, Futami K, Ghallab EHS, Girod R, Gordeev MI, Greer D, Gschwind M, Guarido MM, Guat Ney T, Gunay F, Haklay E, Hamad AAE, Hang J, Hardy CM, Hartle JW, Hesson JC, Higa Y, Holzapfel CM, Honnen AC, Ionica AM, Jones L, Kadriaj P, Kamal HA, Kamdem C, Karagodin DA, Kasai S, Kavran M, Khater EIM, Kiene F, Kim HC, Kioulos I, Klein A, Klemenčić M, Klobučar A, Knutson E, Koenraadt CJM, Kothera L, Kreienbühl P, Labbé P, Lachmi I, Lambrechts L, Landeka N, Lee CH, Lessard BD, Leycegui I, Lundström JO, Lustigman Y, MacIntyre C, Mackay AJ, Magori K, Maia C, Malcolm CA, Marquez RO, Martins D, Masri RA, McDivitt G, McMinn RJ, Medina J, Mellor KS, Mendoza J, Merdić E, Mesler S, Mestre C, Miranda H, Miterpáková M, Montarsi F, Moskaev AV, Mu T, Möhlmann TWR, Namias A, Ng'iru I, Ngangué MF, Novo MT, Orshan L, Oteo JA, Otsuka Y, Panarese R, Paredes-Esquivel C, Paronyan L, Peper ST, Petrić DV, Pilapil K, Pou-Barreto C, Puechmaille SJ, Radespiel U, Rahola N, Raman VK, Redouane H, Reiskind MH, Reissen NM, Rice BL, Robert V, Ruiz-Arrondo I, Salamat R, Salamone A, Sarih M, Satta G, Sawabe K, Schaffner F, Schultz KE, Shaikevich EV, Sharakhov IV, Sharakhova MV, Shatara N, Sibataev AK, Sicard M, Smith E, Smith RC, Smitz N, Soriano N, Spanoudis CG, Stone CM, Studentsky L, Sulesco T, Tantely LM, Thao K, Tietze N, Tokarz RE, Tsai KH, Tsuda Y, Turić N, Uhran MR, Unlu I, Van Bortel W, Vardanyan H, Vavassori L, Velo E, Venter M, Vignjević G, Vogels CBF, Volkava T, Vontas J, Ward HM, Wasi Ahmad N, Weill M, West JD, Wheeler SS, White GS, Wipf NC, Wu TP, Yu KD, Zimmermann E, Zittra C. Science. 2025 Oct 23; 2025 Oct 23. PMID: 41129649.
A Human Neural Tube Model Using 4D Self-Folding Smart Scaffolds.Dell'Amico C, Chiesa I, Toffano A, Esposito A, Mancini P, Magliaro C, Louvi A, De Maria C, Onorati M. Adv Healthc Mater. 2025 Oct 23; 2025 Oct 23. PMID: 41126690.