Recent Publications

Engaging Parents of Children With Sickle Cell Disease in Shared Decision-Making for Hydroxyurea: The ENGAGE-HU Study.Hildenbrand AK, Mara CA, Murphy B, Hood AM, Johnson Y, Shook LM, Real FJ, Nwankwo C, Hackworth R, Badawy SM, Thompson AA, Raphael JL, Smith-Whitley K, King AA, Calhoun C, Creary SE, Reader SK, Bhasin N, Sobota AE, Houston P, Gipson C, DeBaun MR, Saving KL, Treadwell M, Quinn CT, Crosby LE. Pediatr Blood Cancer. 2025 May; 2025 Mar 6. PMID: 40051208.
HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy.Jiang Q, Braun DA, Clauser KR, Ramesh V, Shirole NH, Duke-Cohan JE, Nabilsi N, Kramer NJ, Forman C, Lippincott IE, Klaeger S, Phulphagar KM, Chea V, Kim N, Vanasse AP, Saad E, Parsons T, Carr-Reynolds M, Carulli I, Pinjusic K, Jiang Y, Li R, Syamala S, Rachimi S, Verzani EK, Stevens JD, Lane WJ, Camp SY, Meli K, Pappalardi MB, Herbert ZT, Qiu X, Cejas P, Long HW, Shukla SA, Van Allen EM, Choueiri TK, Churchman LS, Abelin JG, Gurer C, MacBeath G, Childs RW, Carr SA, Keskin DB, Wu CJ, Kaelin WG Jr. Cell. 2025 Apr 3; 2025 Feb 28. PMID: 40023154.
Nonselective β-Adrenergic Receptor Inhibitors Impair Hematopoietic Regeneration in Mice and Humans after Hematopoietic Cell Transplants.Nishino J, Hu W, Kishtagari A, Shen B, Gao X, Blackman CM, Kassim A, Marneni N, Cherukuri AV, Vittrup R, Kalkan FN, Shah R, Ahn C, Gao A, Ahmedrabie A, Collins RH, Zeidan AM, Bidikian A, Gowda L, Shaffer BC, Madanat YF, Zhao Z, Chung SS, Morrison SJ. Cancer Discov. 2025 Apr 2. PMID: 39786370.
The interplay between Salmonella and host: Mechanisms and strategies for bacterial survival.Zhao H, Zhang X, Zhang N, Zhu L, Lian H. Cell Insight. 2025 Apr; 2025 Feb 13. PMID: 40177681.
Pluripotent cell states and fates in human embryo models.Sozen B, Tam PPL, Pera MF. Development. 2025 Apr 1; 2025 Apr 2. PMID: 40171916.
MFGE-8, a Corona Protein on Extracellular Vesicles, Mediates Self-Renewal and Survival of Human Pluripotent Stem Cells.Lee Y, Kim H, Yoon H, Cho S, Kim J, Lee J, Choi SH, Cho H, Woo DH, Park JH, Han C, Kim JH. J Extracell Vesicles. 2025 Apr. PMID: 40130745.
Microstructural patterns in substantia nigra subregions are associated with depression and olfactory impairments in Parkinson's disease.Mozafar M, Manshadi ZD, Molaei Z, Babaei H, Mansouri M, Shahbazi S, Shakeri S, Mirhosseini H, Gulisashvili D, Mayeli M. Clin Neurol Neurosurg. 2025 Apr; 2025 Mar 8. PMID: 40080943.
Modeling forebrain regional development and connectivity by human brain organoids.Choe MS, Lo C, Park IH. Curr Opin Genet Dev. 2025 Apr; 2025 Feb 20. PMID: 39983347.
Chimerism testing in myeloid malignancies: techniques, considerations, and connections to post-transplant outcomes.Puzo CJ, Siddon AJ. Pathology. 2025 Apr; 2025 Jan 17. PMID: 39934013.
Alemtuzumab and thrombotic thrombocytopenic purpura: Analysis of an international surveillance database and systematic literature review.Jacobs JW, Binns TC, Schlafer D, Woo JS, Booth GS, Adkins BD. Transfus Apher Sci. 2025 Apr; 2025 Jan 27. PMID: 39883995.
The maternal-to-zygotic transition: reprogramming of the cytoplasm and nucleus.Kojima ML, Hoppe C, Giraldez AJ. Nat Rev Genet. 2025 Apr; 2024 Nov 25. PMID: 39587307.
Durable mixed chimerism may permit subsequent immunosuppression-free intestinal transplantation-A proof-of-principle study.Patwardhan S, Gunes ME, Manell E, Hong J, Jordache P, Chauhan I, Almesallmy A, Mulder H, Ekanayake-Alper D, Hajosi D, Ko HM, Shanmugarajah K, Cetrulo CL, Nowak G, Sachs DH, Sykes M, Weiner J. Am J Transplant. 2025 Apr; 2024 Oct 22. PMID: 39442670.
Rethinking AMPK: A Reversible Switch Fortifying Cancer Cell Stress-Resilience.Mohanty SS, Warrier S, Rangarajan A. Yale J Biol Med. 2025 Mar; 2025 Mar 31. PMID: 40165808.
Invigorating discovery and clinical translation of aging biomarkers.Jacques E, Herzog C, Ying K, Tomusiak A, Kasamoto J, Sehgal R, Paulson S, Reinhard J, Träuble J, Hastings WJ, Tyshkovskiy A, Hägg S, Earls JC, Behrens CE, Lasky-Su J, Zhou G, Morgen E, Tsang JS, Marioni RE, Ma XJ, Stolzing A, Glorioso C, Gootenberg JS, Abudayyeh OO, Argentieri MA, Mak RH, Cox LS, Brack AS, Lauc G, Furman D, Buenrostro JD, Schumacher B, Justice JN, Woods T, Gobel D, Perez VI, Sinclair DA, Maier AB, Barzilai N, Snyder MP, Wyss-Coray T, Horvath S, Ferrucci L, Poganik JR, Moqri M, Gladyshev VN. Nat Aging. 2025 Mar 31; 2025 Mar 31. PMID: 40164770.
An in vivo screen identifies NAT10 as a master regulator of brain metastasis.Chen JF, Xu P, Cai WL, Chen H, Wingrove E, Shi X, Li W, Biancon G, Zhang M, Balabaki A, Krop ED, Asare E, Zhang Y, Yin M, Tebaldi T, Meier JL, Westbrook TF, Halene S, Liu Y, Shen H, Nguyen DX, Yan Q. Sci Adv. 2025 Mar 28; 2025 Mar 26. PMID: 40138393.
Generation of Orthogonal Gradients of the Matrix Stiffness and Chemotactic Cues in a Suspended Array of Hydrogel to Study hMSCs Migration.Xu Z, Ponek A, Thomas J, Qyang Y. ACS Sens. 2025 Mar 28; 2025 Feb 28. PMID: 40021359.
Contemporary understanding of myeloid-derived suppressor cells in the acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) tumor microenvironment.Alhajahjeh A, Stahl M, Kim TK, Kewan T, Stempel JM, Zeidan AM, Bewersdorf JP. Expert Rev Anticancer Ther. 2025 Mar 27; 2025 Mar 27. PMID: 40122075.
A Blueprint for Translational Precision Medicine in Autism Spectrum Disorder and Related Neurogenetic Syndromes.Thom RP, Warren TL, Khan S, Muhle RA, Wang PP, Brennand K, Zürcher NR, Veenstra-VanderWeele J, Hoffman EJ. J Child Adolesc Psychopharmacol. 2025 Mar 26; 2025 Mar 26. PMID: 40138183.
Spatially resolved genome-wide joint profiling of epigenome and transcriptome with spatial-ATAC-RNA-seq and spatial-CUT&Tag-RNA-seq.Li H, Bao S, Farzad N, Qin X, Fung AA, Zhang D, Bai Z, Tao B, Fan R. Nat Protoc. 2025 Mar 21; 2025 Mar 21. PMID: 40119005.
Scientific Advancements in Gene Therapies: Opportunities for Global Regulatory Convergence.Olaghere J, Williams DA, Farrar J, Büning H, Calhoun C, Ho T, Inamdar MS, Liu D, Makani J, Nyarko K, Ruiz S, Tisdale J, McCune JM, Boadi E, Reagan-Udall Foundation For The Fda. Biomedicines. 2025 Mar 20; 2025 Mar 20. PMID: 40149734.
Cas12a-knock-in mice for multiplexed genome editing, disease modelling and immune-cell engineering.Tang K, Zhou L, Tian X, Fang SY, Vandenbulcke E, Du A, Shen J, Cao H, Zhou J, Chen K, Kim HR, Luo Z, Xin S, Lin SH, Park D, Yang L, Zhang Y, Suzuki K, Majety M, Ling X, Lam SZ, Chow RD, Ren P, Tao B, Li K, Codina A, Dai X, Shang X, Bai S, Nottoli T, Levchenko A, Booth CJ, Liu C, Fan R, Dong MB, Zhou X, Chen S. Nat Biomed Eng. 2025 Mar 20; 2025 Mar 20. PMID: 40114032.
Resolving the three-dimensional interactome of human accelerated regions during human and chimpanzee neurodevelopment.Pal A, Noble MA, Morales M, Pal R, Baumgartner M, Yang JW, Yim KM, Uebbing S, Noonan JP. Cell. 2025 Mar 20; 2025 Jan 30. PMID: 39889695.
Initial management of patients with acquired aplastic anemia in the United States: results from a large national claims database.Stempel JM, Wang R, Lee AI, Zeidan AM, Ma X, Podoltsev NA. Ann Hematol. 2025 Mar 19; 2025 Mar 19. PMID: 40102305.
Quantitative characterization of cell niches in spatially resolved omics data.Birk S, Bonafonte-Pardàs I, Feriz AM, Boxall A, Agirre E, Memi F, Maguza A, Yadav A, Armingol E, Fan R, Castelo-Branco G, Theis FJ, Bayraktar OA, Talavera-López C, Lotfollahi M. Nat Genet. 2025 Mar 18; 2025 Mar 18. PMID: 40102688.
Low Penetrance Sarcomere Variants Contribute to Additive Risk in Hypertrophic Cardiomyopathy.Meisner JK, Renberg A, Smith ED, Tsan YC, Elder B, Bullard A, Merritt OL, Zheng SL, Lakdawala NK, Owens AT, Ryan TD, Miller EM, Rossano JW, Lin KY, Claggett BL, Ashley EA, Michels M, Lampert R, Stendahl JC, Abrams D, Semsarian C, Parikh VN, Wheeler MT, Ingles J, Olivotto I, Day SM, Saberi S, Russell MW, Previs M, Ho CY, Ware JS, Helms AS. Circulation. 2025 Mar 18; 2024 Dec 5. PMID: 39633578.
Deciphering lung adenocarcinoma evolution and the role of LINE-1 retrotransposition.Zhang T, Zhao W, Wirth C, Díaz-Gay M, Yin J, Cecati M, Marchegiani F, Hoang PH, Leduc C, Baine MK, Travis WD, Sholl LM, Joubert P, Sang J, McElderry JP, Klein A, Khandekar A, Hartman C, Rosenbaum J, Colón-Matos FJ, Miraftab M, Saha M, Lee OW, Jones KM, Caporaso NE, Wong MP, Leung KC, Agnes Hsiung C, Chen CY, Edell ES, Martínez Santamaría J, Schabath MB, Yendamuri SS, Manczuk M, Lissowska J, Świątkowska B, Mukeria A, Shangina O, Zaridze D, Holcatova I, Mates D, Milosavljevic S, Savic M, Bossé Y, Gould Rothberg BE, Christiani DC, Gaborieau V, Brennan P, Liu G, Hofman P, Homer R, Yang SR, Pesatori AC, Consonni D, Yang L, Zhu B, Shi J, Brown K, Rothman N, Chanock SJ, Alexandrov LB, Choi J, Cardelli M, Lan Q, Nowak MA, Wedge DC, Landi MT. bioRxiv. 2025 Mar 16; 2025 Mar 16. PMID: 40161734.
Moderators of digital cognitive-behavioral therapy for youth with sickle cell disease pain: secondary analysis of a randomized controlled trial.Palermo TM, Srinakarin K, Zhou C, Lalloo C, Dampier C, Zempsky WT, Badawy SM, Bakshi N, Ko YJ, Nishat F, Stinson JN. Pain. 2025 Mar 13; 2025 Mar 13. PMID: 40085012.
Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells.Luo C, Zhang R, Guo R, Wu L, Xue T, He Y, Jin Y, Zhao Y, Zhang Z, Zhang P, Ye S, Li X, Li D, Zhang W, Wang C, Lai L, Pan-Hammarström Q, Wucherpfennig KW, Gao Z, Pan D, Zeng Z. Immunity. 2025 Mar 11; 2025 Feb 28. PMID: 40023158.
Advancing drug development in myelodysplastic syndromes.Mina A, McGraw KL, Cunningham L, Kim N, Jen EY, Calvo KR, Ehrlich LA, Aplan PD, Garcia-Manero G, Foran JM, Garcia JS, Zeidan AM, DeZern AE, Komrokji R, Sekeres MA, Scott B, Buckstein R, Tinsley-Vance S, Verma A, Wroblewski T, Pavletic S, Norsworthy K. Blood Adv. 2025 Mar 11. PMID: 39786387.
Hematopoietic cell transplant compared with standard care in adolescents and young adults with sickle cell disease.Walters MC, Eapen M, Liu Y, El Rassi F, Waller EK, Levine JE, Strouse JJ, Antin JH, Parikh SH, Bakshi N, Dampier C, Jaroscak JJ, Bergmann S, Wong T, Kota V, Pace B, Lekakis LJ, Lulla P, Nickel RS, Kasow KA, Popat U, Smith W, Yu L, DiFronzo N, Geller N, Kamani N, Klings ES, Hassell K, Mendizabal A, Sullivan K, Neuberg D, Krishnamurti L. Blood Adv. 2025 Mar 11. PMID: 39471440.
The effect of plerixafor on autologous stem cell mobilization, cell viability, and apheresis challenges.Puzo CJ, Li P, Tormey CA, Siddon AJ. Lab Med. 2025 Mar 10. PMID: 39303673.
Modeling SMAD2 Mutations in Induced Pluripotent Stem Cells Provides Insights Into Cardiovascular Disease Pathogenesis.Ward T, Morton SU, Venturini G, Tai W, Jang MY, Gorham J, Delaughter D, Wasson LK, Khazal Z, Homsy J, Gelb BD, Chung WK, Bruneau BG, Brueckner M, Tristani-Firouzi M, DePalma SR, Seidman C, Seidman JG. J Am Heart Assoc. 2025 Mar 4; 2025 Mar 3. PMID: 40028843.
Subcellular proteomics and iPSC modeling uncover reversible mechanisms of axonal pathology in Alzheimer's disease.Cai Y, Kanyo J, Wilson R, Bathla S, Cardozo PL, Tong L, Qin S, Fuentes LA, Pinheiro-de-Sousa I, Huynh T, Sun L, Mansuri MS, Tian Z, Gan HR, Braker A, Trinh HK, Huttner A, Lam TT, Petsalaki E, Brennand KJ, Nairn AC, Grutzendler J. Nat Aging. 2025 Mar; 2025 Mar 10. PMID: 40065072.
Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk.Choi SH, Jurgens SJ, Xiao L, Hill MC, Haggerty CM, Sveinbjörnsson G, Morrill VN, Marston NA, Weng LC, Pirruccello JP, Arnar DO, Gudbjartsson DF, Mantineo H, von Falkenhausen AS, Natale A, Tveit A, Geelhoed B, Roselli C, Van Wagoner DR, Darbar D, Haase D, Soliman EZ, Davogustto GE, Jun G, Calkins H, Anderson JL, Brody JA, Halford JL, Barnard J, Hokanson JE, Smith JD, Bis JC, Young K, Johnson LSB, Risch L, Gula LJ, Kwee LC, Chaffin MD, Kühne M, Preuss M, Gupta N, Nafissi NA, Smith NL, Nilsson PM, van der Harst P, Wells QS, Judy RL, Schnabel RB, Johnson R, Smit RAJ, Gabriel S, Knight S, Furukawa T, Blackwell TW, Nauffal V, Wang X, Min YI, Yoneda ZT, Laksman ZWM, Bezzina CR, Alonso A, Psaty BM, Albert CM, Arking DE, Roden DM, Chasman DI, Rader DJ, Conen D, McManus DD, Fatkin D, Benjamin EJ, Boerwinkle E, Marcus GM, Christophersen IE, Smith JG, Roberts JD, Raffield LM, Shoemaker MB, Cho MH, Cutler MJ, Rienstra M, Chung MK, S Olesen M, Sinner MF, Sotoodehnia N, Kirchhof P, Loos RJF, Nazarian S, Mohanty S, Damrauer SM, Kaab S, Heckbert SR, Redline S, Shah SH, Tanaka T, Ebana Y, Holm H, Stefansson K, Ruff CT, Sabatine MS, Lunetta KL, Lubitz SA, Ellinor PT. Nat Genet. 2025 Mar; 2025 Mar 6. PMID: 40050430.
Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases.Roselli C, Surakka I, Olesen MS, Sveinbjornsson G, Marston NA, Choi SH, Holm H, Chaffin M, Gudbjartsson D, Hill MC, Aegisdottir H, Albert CM, Alonso A, Anderson CD, Arking DE, Arnar DO, Barnard J, Benjamin EJ, Braunwald E, Brumpton B, Campbell A, Chami N, Chasman DI, Cho K, Choi EK, Christophersen IE, Chung MK, Conen D, Crijns HJ, Cutler MJ, Czuba T, Damrauer SM, Dichgans M, Dörr M, Dudink E, Duong T, Erikstrup C, Esko T, Fatkin D, Faul JD, Ferreira M, Freitag DF, Ganesh SK, Gaziano JM, Geelhoed B, Ghouse J, Gieger C, Giulianini F, Graham SE, Gudnason V, Guo X, Haggerty C, Hayward C, Heckbert SR, Hveem K, Ito K, Johnson R, Jukema JW, Jurgens SJ, Kääb S, Kane JP, Kany S, Kardia SLR, Kavousi M, Khurshid S, Kamanu FK, Kirchhof P, Kleber ME, Knight S, Komuro I, Krieger JE, Launer LJ, Li D, Lin H, Lin HJ, Loos RJF, Lotta L, Lubitz SA, Lunetta KL, Macfarlane PW, Magnusson PKE, Malik R, Mantineo H, Marcus GM, März W, McManus DD, Melander O, Melloni GEM, Meyre PB, Miyazawa K, Mohanty S, Monfort LM, Müller-Nurasyid M, Nafissi NA, Natale A, Nazarian S, Ostrowski SR, Pak HN, Pang S, Pedersen OB, Pedersen NL, Pereira AC, Pirruccello JP, Preuss M, Psaty BM, Pullinger CR, Rader DJ, Rämö JT, Ridker PM, Rienstra M, Risch L, Roden DM, Rotter JI, Sabatine MS, Schunkert H, Shah SH, Shim J, Shoemaker MB, Simonson B, Sinner MF, Smit RAJ, Smith JA, Smith NL, Smith JG, Soliman EZ, Sørensen E, Sotoodehnia N, Strbian D, Stricker BH, Teder-Laving M, Sun YV, Thériault S, Thorolfsdottir RB, Thorsteinsdottir U, Tveit A, van der Harst P, van Meurs J, Wang B, Weiss S, Wells QS, Weng LC, Wilson PW, Xiao L, Yang PS, Yao J, Yoneda ZT, Zeller T, Zeng L, Zhao W, Zhou X, Zöllner S, Ruff CT, Bundgaard H, Willer C, Stefansson K, Ellinor PT. Nat Genet. 2025 Mar; 2025 Mar 6. PMID: 40050429.
Haploidentical Bone Marrow Transplantation for Sickle Cell Disease.Kassim AA, Walters MC, Eapen M, Smith M, Logan BR, Solh M, McKinney C, Nieder M, Ross M, Kent M, Abusin GA, Mallhi K, Silva JG, Shaughnessy P, Kanter J, Haines H, Farah R, Khaled YA, Ritzau N, Mendizabal A, Abraham A, Bollard C, Cooke K, de la Fuente J, Hanna R, Horowitz MM, Jordan LC, Bakshi N, Krishnamurti L, Leifer E, Mahadeo KM, Shenoy S, Jones RJ, DeBaun MR, Brodsky RA. NEJM Evid. 2025 Mar; 2025 Feb 25. PMID: 39998298.
PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors.DeSpenza T Jr, Kiziltug E, Allington G, Barson DG, McGee S, O'Connor D, Robert SM, Mekbib KY, Nanda P, Greenberg ABW, Singh A, Duy PQ, Mandino F, Zhao S, Lynn A, Reeves BC, Marlier A, Getz SA, Nelson-Williams C, Shimelis H, Walsh LK, Zhang J, Wang W, Prina ML, OuYang A, Abdulkareem AF, Smith H, Shohfi J, Mehta NH, Dennis E, Reduron LR, Hong J, Butler W, Carter BS, Deniz E, Lake EMR, Constable RT, Sahin M, Srivastava S, Winden K, Hoffman EJ, Carlson M, Gunel M, Lifton RP, Alper SL, Jin SC, Crair MC, Moreno-De-Luca A, Luikart BW, Kahle KT. Nat Neurosci. 2025 Mar; 2025 Feb 24. PMID: 39994410.
Pharmacological Enhancement of Adult Hippocampal Neurogenesis Improves Behavioral Pattern Separation in Young and Aged Male Mice.Chang WL, Tegang K, Samuels BA, Saxe M, Wichmann J, David DJ, David IM, Augustin A, Fischer H, Golling S, Lamerz J, Roth D, Graf M, Zoffmann S, Santarelli L, Jagasia R, Hen R. Biol Psychiatry Glob Open Sci. 2025 Mar; 2024 Nov 20. PMID: 39830600.
A framework for neural organoids, assembloids and transplantation studies.Pașca SP, Arlotta P, Bateup HS, Camp JG, Cappello S, Gage FH, Knoblich JA, Kriegstein AR, Lancaster MA, Ming GL, Novarino G, Okano H, Parmar M, Park IH, Reiner O, Song H, Studer L, Takahashi J, Temple S, Testa G, Treutlein B, Vaccarino FM, Vanderhaeghen P, Young-Pearse T. Nature. 2025 Mar; 2024 Dec 9. PMID: 39653126.
Multiple intravenous infusions versus a single infusion of mesenchymal stem cells in a rat model of cerebral ischemia.Yokoyama T, Sasaki M, Nagahama H, Kataoka-Sasaki Y, Ukai R, Oka S, Kocsis JD, Honmou O. J Neurosurg. 2025 Mar 1; 2024 Oct 25. PMID: 39454218.
Enhanced Intratumoral Delivery of Immunomodulator Monophosphoryl Lipid A through Hyperbranched Polyglycerol-Coated Biodegradable Nanoparticles.Chang J, Shin K, Lewis JM, Suh HW, Lee J, Damsky W, Xu S, Bosenberg M, Saltzman WM, Girardi M. J Invest Dermatol. 2025 Mar; 2024 Aug 8. PMID: 39122142.
Molecular and cellular neurocardiology in heart disease.Habecker BA, Bers DM, Birren SJ, Chang R, Herring N, Kay MW, Li D, Mendelowitz D, Mongillo M, Montgomery JM, Ripplinger CM, Tampakakis E, Winbo A, Zaglia T, Zeltner N, Paterson DJ. J Physiol. 2025 Mar; 2024 May 22. PMID: 38778747.
Engineering Mice to Study Human Immunity.Sefik E, Xiao T, Chiorazzi M, Odell I, Zhang F, Agrawal K, Micevic G, Flavell RA. Annu Rev Immunol. 2025 Feb 28; 2025 Feb 28. PMID: 40020225.
Examination of germline and somatic intercellular bridges in Hydra vulgaris reveals insights into the evolutionarily conserved mechanism of intercellular bridge formation.Price KL, Tharakan DM, Salvenmoser W, Ayers K, Mah J, Dunn C, Hobmayer B, Cooley L. bioRxiv. 2025 Feb 20; 2025 Feb 20. PMID: 40027827.
Long-Term Engraftment of Cryopreserved Human Neurons for In Vivo Disease Modeling in Neurodegenerative Disease.Marmion DJ, Deng P, Hiller BM, Lewis RL, Harms LJ, Cameron DL, Nolta JA, Kordower JH, Fink KD, Wakeman DR. Biology (Basel). 2025 Feb 19; 2025 Feb 19. PMID: 40001985.
US Geriatric Assessment Practices for Older Adults Undergoing Hematopoietic Cell Transplantation or Chimeric Antigen Receptor T Cell Therapy: An American Society for Transplantation and Cellular Therapy Physician Survey from the Aging Special Interest Group and Committee on Practice Guidelines.Munshi PN, Olin RL, Wall S, McCurdy SR, Al-Juhaishi T, Baker J, Bhatt VR, Chokr N, Dahi P, DeFilipp Z, Espinoza-Gutarra M, Farhan S, Gowda L, Hamilton BK, Inamoto Y, Jayani R, Kharfan-Dabaja MA, Lin R, Meyers G, Mishra A, Murthy HS, Nawas M, Rosko AE, Ruiz M, Sorror ML, Sung AD, Carpenter PA, Hamadani M, Artz AS. Transplant Cell Ther. 2025 Feb 15; 2025 Feb 15. PMID: 39961473.
Symposia Report of The Annual Biological Sciences Section Meeting of the Gerontological Society of America 2023, Tampa, Florida.Rogina B, Anderson R, Lebrasseur N, Curan S, Yousefzadeh MJ, Ghosh B, Duque G, Howlett S, Austad S, Demuth I, Gerstorf D, Korfhage J, Lombard DB, Abadir P, Christensen K, Carey JR, Alberts SC, Campos F, Palavicini JP, Palmer A, Bell J, Basisty N, de Cabo R, Gomes A, Dixit VD, Sen P, Baur JA, Imai SI, Li X, Valdez G, Orr ME, Pletcher S, Andersen J, Jones L, Castillo-Azofeida D, Bonaguidi M, Suh Y, Duncan FE, Murray A, Wang MC, Burkewitz K, Henne M, Zhou K, Bouhrara M, Benjamini D, Kolind S, Walker KA, Reiter DA, Dean Iii D, Gorbunova V, Gladyshev VN, Palovics R, Niedernhofer LJ, Fan R, Bueckle AD, Hurley J, Esser KA, Kapahi P, Sato S, Jiang N, Ashiqueali SA, Diaz J, Mishra SP, Ralmundo N, Banarjee R, Allsopp R, Reynolds LM, Zhang B, Sebastiani P, Monti S, Schork N, Rappaport N. J Gerontol A Biol Sci Med Sci. 2025 Feb 11; 2025 Feb 11. PMID: 39932386.
Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology.Gould E, Fraser HS, Parker TH, Nakagawa S, Griffith SC, Vesk PA, Fidler F, Hamilton DG, Abbey-Lee RN, Abbott JK, Aguirre LA, Alcaraz C, Aloni I, Altschul D, Arekar K, Atkins JW, Atkinson J, Baker CM, Barrett M, Bell K, Bello SK, Beltrán I, Berauer BJ, Bertram MG, Billman PD, Blake CK, Blake S, Bliard L, Bonisoli-Alquati A, Bonnet T, Bordes CNM, Bose APH, Botterill-James T, Boyd MA, Boyle SA, Bradfer-Lawrence T, Bradham J, Brand JA, Brengdahl MI, Bulla M, Bussière L, Camerlenghi E, Campbell SE, Campos LLF, Caravaggi A, Cardoso P, Carroll CJW, Catanach TA, Chen X, Chik HYJ, Choy ES, Christie AP, Chuang A, Chunco AJ, Clark BL, Contina A, Covernton GA, Cox MP, Cressman KA, Crotti M, Crouch CD, D'Amelio PB, de Sousa AA, Döbert TF, Dobler R, Dobson AJ, Doherty TS, Drobniak SM, Duffy AG, Duncan AB, Dunn RP, Dunning J, Dutta T, Eberhart-Hertel L, Elmore JA, Elsherif MM, English HM, Ensminger DC, Ernst UR, Ferguson SM, Fernandez-Juricic E, Ferreira-Arruda T, Fieberg J, Finch EA, Fiorenza EA, Fisher DN, Fontaine A, Forstmeier W, Fourcade Y, Frank GS, Freund CA, Fuentes-Lillo E, Gandy SL, Gannon DG, García-Cervigón AI, Garretson AC, Ge X, Geary WL, Géron C, Gilles M, Girndt A, Gliksman D, Goldspiel HB, Gomes DGE, Good MK, Goslee SC, Gosnell JS, Grames EM, Gratton P, Grebe NM, Greenler SM, Griffioen M, Griffith DM, Griffith FJ, Grossman JJ, Güncan A, Haesen S, Hagan JG, Hager HA, Harris JP, Harrison ND, Hasnain SS, Havird JC, Heaton AJ, Herrera-Chaustre ML, Howard TJ, Hsu BY, Iannarilli F, Iranzo EC, Iverson ENK, Jimoh SO, Johnson DH, Johnsson M, Jorna J, Jucker T, Jung M, Kačergytė I, Kaltz O, Ke A, Kelly CD, Keogan K, Keppeler FW, Killion AK, Kim D, Kochan DP, Korsten P, Kothari S, Kuppler J, Kusch JM, Lagisz M, Lalla KM, Larkin DJ, Larson CL, Lauck KS, Lauterbur ME, Law A, Léandri-Breton DJ, Lembrechts JJ, L'Herpiniere K, Lievens EJP, de Lima DO, Lindsay S, Luquet M, MacLeod R, Macphie KH, Magellan K, Mair MM, Malm LE, Mammola S, Mandeville CP, Manhart M, Manrique-Garzon LM, Mäntylä E, Marchand P, Marshall BM, Martin CA, Martin DA, Martin JM, Martinig AR, McCallum ES, McCauley M, McNew SM, Meiners SJ, Merkling T, Michelangeli M, Moiron M, Moreira B, Mortensen J, Mos B, Muraina TO, Murphy PW, Nelli L, Niemelä P, Nightingale J, Nilsonne G, Nolazco S, Nooten SS, Novotny JL, Olin AB, Organ CL, Ostevik KL, Palacio FX, Paquet M, Parker DJ, Pascall DJ, Pasquarella VJ, Paterson JH, Payo-Payo A, Pedersen KM, Perez G, Perry KI, Pottier P, Proulx MJ, Proulx R, Pruett JL, Ramananjato V, Randimbiarison FT, Razafindratsima OH, Rennison DJ, Riva F, Riyahi S, Roast MJ, Rocha FP, Roche DG, Román-Palacios C, Rosenberg MS, Ross J, Rowland FE, Rugemalila D, Russell AL, Ruuskanen S, Saccone P, Sadeh A, Salazar SM, Sales K, Salmón P, Sánchez-Tójar A, Santos LP, Santostefano F, Schilling HT, Schmidt M, Schmoll T, Schneider AC, Schrock AE, Schroeder J, Schtickzelle N, Schultz NL, Scott DA, Scroggie MP, Shapiro JT, Sharma N, Shearer CL, Simón D, Sitvarin MI, Skupien FL, Slinn HL, Smith GP, Smith JA, Sollmann R, Whitney KS, Still SM, Stuber EF, Sutton GF, Swallow B, Taff CC, Takola E, Tanentzap AJ, Tarjuelo R, Telford RJ, Thawley CJ, Thierry H, Thomson J, Tidau S, Tompkins EM, Tortorelli CM, Trlica A, Turnell BR, Urban L, Van de Vondel S, van der Wal JEM, Van Eeckhoven J, van Oordt F, Vanderwel KM, Vanderwel MC, Vanderwolf KJ, Vélez J, Vergara-Florez DC, Verrelli BC, Vieira MV, Villamil N, Vitali V, Vollering J, Walker J, Walker XJ, Walter JA, Waryszak P, Weaver RJ, Wedegärtner REM, Weller DL, Whelan S, White RL, Wolfson DW, Wood A, Yanco SW, Yen JDL, Youngflesh C, Zilio G, Zimmer C, Zimmerman GM, Zitomer RA. BMC Biol. 2025 Feb 6; 2025 Feb 6. PMID: 39915771.
Ancient origin of an urban underground mosquito.Haba Y, Aardema ML, Afonso MO, Agramonte NM, Albright J, Alho AM, Almeida APG, Alout H, Alten B, Altinli M, Amara Korba R, Andreadis SS, Anghel V, Arich S, Arsenault-Benoit A, Atyame C, Aubry F, Avila FW, Ayala D, Azrag RS, Babayan L, Bear A, Becker N, Bega AG, Bejarano S, Ben-Avi I, Benoit JB, Boubidi SC, Bradshaw WE, Bravo-Barriga D, Bueno-Marí R, Bušić N, Čabanová V, Cabeje B, Caputo B, Cardo MV, Carpenter S, Carreton E, Chouaïbou MS, Christian M, Coetzee M, Conner WR, Cornel A, Culverwell CL, Cupina AI, De Wolf K, Deblauwe I, Deegan B, Delacour-Estrella S, Torre AD, Diaz D, Dool SE, Dos Anjos VL, Dugassa S, Ebrahimi B, Eisa SYM, Elissa N, Fallatah SAB, Faraji A, Fedorova MV, Ferrill E, Fonseca DM, Foss KA, Foxi C, França CM, Fricker SR, Fritz ML, Frontera E, Fuehrer HP, Futami K, Ghallab EHS, Girod R, Gordeev MI, Greer D, Gschwind M, Guarido MM, Guat Ney T, Gunay F, Haklay E, Hamad AAE, Hang J, Hardy CM, Hartle JW, Hesson JC, Higa Y, Holzapfel CM, Honnen AC, Ionica AM, Jones L, Kadriaj P, Kamal HA, Kamdem C, Karagodin DA, Kasai S, Kavran M, Khater EIM, Kiene F, Kim HC, Kioulos I, Klein A, Klemenčić M, Klobučar A, Knutson E, Koenraadt CJM, Kothera L, Kreienbühl P, Labbé P, Lachmi I, Lambrechts L, Landeka N, Lee CH, Lessard BD, Leycegui I, Lundström JO, Lustigman Y, MacIntyre C, Mackay AJ, Magori K, Maia C, Malcolm CA, Marquez RO, Martins D, Masri RA, McDivitt G, McMinn RJ, Medina J, Mellor KS, Mendoza J, Merdić E, Mesler S, Mestre C, Miranda H, Miterpáková M, Montarsi F, Moskaev AV, Mu T, Möhlmann TWR, Namias A, Ng'iru I, Ngangué MF, Novo MT, Orshan L, Oteo JA, Otsuka Y, Panarese R, Paredes-Esquivel C, Paronyan L, Peper ST, Petrić DV, Pilapil K, Pou-Barreto C, Puechmaille SJ, Radespiel U, Rahola N, Raman VK, Redouane H, Reiskind MH, Reissen NM, Rice BL, Robert V, Ruiz-Arrondo I, Salamat R, Salamone A, Sarih M, Satta G, Sawabe K, Schaffner F, Schultz KE, Shaikevich EV, Sharakhov IV, Sharakhova MV, Shatara N, Sibataev AK, Sicard M, Smith E, Smith RC, Smitz N, Soriano N, Spanoudis CG, Stone CM, Studentsky L, Sulesco T, Tantely LM, Thao K, Tietze N, Tokarz RE, Tsai KH, Tsuda Y, Turić N, Uhran MR, Unlu I, Van Bortel W, Vardanyan H, Vavassori L, Velo E, Venter M, Vignjević G, Vogels CBF, Volkava T, Vontas J, Ward HM, Ahmad NW, Weill M, West JD, Wheeler SS, White GS, Wipf NC, Wu TP, Yu KD, Zimmermann E, Zittra C, Korlević P, McAlister E, Lawniczak MKN, Schumer M, Rose NH, McBride CS. bioRxiv. 2025 Feb 5; 2025 Feb 5. PMID: 39975080.
Determinants of 5-year survival in patients with advanced NSCLC with PD-L1≥50% treated with first-line pembrolizumab outside of clinical trials: results from the Pembro-real 5Y global registry.Cortellini A, Brunetti L, Di Fazio GR, Garbo E, Pinato DJ, Naidoo J, Katz A, Loza M, Neal JW, Genova C, Gettinger S, Kim SY, Jayakrishnan R, El Zarif T, Russano M, Pecci F, Di Federico A, Awad M, Alessi JV, Montrone M, Owen DH, Signorelli D, Fidler MJ, Li M, Camerini A, De Giglio A, Young L, Vincenzi B, Metro G, Passiglia F, Yendamuri S, Guida A, Ghidini M, Awosika NO, Napolitano A, Fulgenzi CAM, Grisanti S, Grossi F, D'Incecco A, Josephides E, Van Hemelrijck M, Russo A, Gelibter A, Spinelli G, Verrico M, Tomasik B, Giusti R, Newsom-Davis T, Bria E, Sebastian M, Rost M, Forster M, Mukherjee U, Landi L, Mazzoni F, Aujayeb A, Dupont M, Curioni-Fontecedro A, Chiari R, Pantano F, Morabito A, Leonetti A, Friedlaender A, Addeo A, Zoratto F, De Tursi M, Cantini L, Roca E, Mountzios G, Della Gravara L, Kalvapudi S, Inno A, Bironzo P, Di Marco Barros R, O'Reilly D, Bell J, Karapanagiotou E, Monnet I, Baena J, Macerelli M, Majem M, Agustoni F, Cortinovis DL, Tonini G, Minuti G, Bennati C, Mezquita L, Gorría T, Servetto A, Beninato T, Lo Russo G, Rogado J, Moliner L, Biello F, Aboubakar Nana F, Dingemans AM, Aerts JGJV, Ferrara R, Torri V, Hejleh TA, Takada K, Naqash AR, Garassino M, Peters S, Wakelee H, Nassar AH, Ricciuti B. J Immunother Cancer. 2025 Feb 4; 2025 Feb 4. PMID: 39904562.
CircRNAs increase during vascular cell differentiation and are biomarkers for vascular disease.Northoff BH, Herbst A, Wenk C, Weindl L, Gäbel G, Brezski A, Zarnack K, Küpper A, Dimmeler S, Moretti A, Laugwitz KL, Engelhardt S, Maegdefessel L, Boon R, Doppler S, Dreßen M, Lahm H, Lange R, Krane M, Krohn K, Kohlmaier A, Holdt LM, Teupser D. Cardiovasc Res. 2025 Feb 4; 2025 Feb 4. PMID: 39901821.
Author Correction: Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy.Zhang F, Chow RD, He E, Dong C, Xin S, Mirza D, Feng Y, Tian X, Verma N, Majety M, Zhang Y, Wang G, Chen S. Nat Biotechnol. 2025 Feb 3; 2025 Feb 3. PMID: 39901026.
Spatiotemporal dynamics of fetal liver hematopoietic niches.Mesquita Peixoto M, Soares-da-Silva F, Bonnet V, Zhou Y, Ronteix G, Santos RF, Mailhe MP, Nogueira G, Feng X, Pereira JP, Azzoni E, Anselmi G, de Bruijn MFTR, Perkins A, Baroud CN, Pinto-do-Ó P, Cumano A. J Exp Med. 2025 Feb 3; 2025 Jan 7. PMID: 39775824.
Advancements in techniques for human iPSC-derived cardiomyocytes maturation: mechanical and electrical stimulation approaches.Lu Y, Liu Y, Yan Y, Fooladi S, Qyang Y. Biophys Rev. 2025 Feb; 2025 Jan 3. PMID: 40060015.
Metabolic rewiring in skin epidermis drives tolerance to oncogenic mutations.Hemalatha A, Li Z, Gonzalez DG, Matte-Martone C, Tai K, Lathrop E, Gil D, Ganesan S, Gonzalez LE, Skala M, Perry RJ, Greco V. Nat Cell Biol. 2025 Feb; 2025 Jan 6. PMID: 39762578.
High p16(INK4A) expression in glioblastoma is associated with senescence phenotype and better prognosis.Park SS, Roh TH, Tanaka Y, Kim YH, Park SH, Kim TG, Eom SY, Park TJ, Park IH, Kim SH, Kim JH. Neoplasia. 2025 Feb; 2024 Dec 25. PMID: 39724755.
Treatment Access among Younger Medicaid Beneficiaries with Multiple Myeloma.Fiala MA, Ji M, Shih YH, Huber J, Wang M, Johnson KJ, Gasoyan H, Wang R, Colditz GA, Wang SY, Chang SH. Clin Lymphoma Myeloma Leuk. 2025 Feb; 2024 Aug 2. PMID: 39209567.
Neural signatures of risk-taking adaptions across health, bipolar disorder, and lithium treatment.Scholl J, Panchal P, Nelissen N, Atkinson LZ, Kolling N, Saunders KE, Geddes J, Rushworth MF, Nobre AC, Harrison PJ, Harmer CJ. Mol Psychiatry. 2025 Jan 29; 2025 Jan 29. PMID: 39880901.
Frozen versus fresh embryo transfer in women with low prognosis for in vitro fertilisation treatment: pragmatic, multicentre, randomised controlled trial.Wei D, Sun Y, Zhao H, Yan J, Zhou H, Gong F, Zhang A, Wang Z, Jin L, Bao H, Zhao S, Xiao Z, Qin Y, Geng L, Cui L, Sheng Y, Sun M, Liu P, Ding L, Liu H, Wu K, Li Y, Lu Y, Xu B, Xu B, Zhang L, Zhang H, Legro RS, Chen ZJ. BMJ. 2025 Jan 29; 2025 Jan 29. PMID: 39880462.
CFTR High Expresser BEST4+ cells are pH-sensing neuropod cells: new implications for intestinal physiology and Cystic Fibrosis disease.Dos Reis DC, Jin J, Santos A, Muiler C, Zagoren E, Donnelley M, Parsons D, Cmielewski P, Reyne N, McCarron A, Smith Z, Sumigray K, Ameen NA. bioRxiv. 2025 Jan 27; 2025 Jan 27. PMID: 39974899.
Epigenetic priming promotes acquisition of tyrosine kinase inhibitor resistance and oncogene amplification in human lung cancer.Starble RM, Sun EG, Gbyli R, Radda J, Lu J, Jensen TB, Sun N, Khudaverdyan N, Hu B, Melnick MA, Zhao S, Roper N, Wang GG, Song J, Politi K, Wang S, Xiao AZ. bioRxiv. 2025 Jan 27; 2025 Jan 27. PMID: 39974875.
One hundred thirty-four germ line PU.1 variants and the agammaglobulinemic patients carrying them.Knox AVC, Cominsky LY, Sun D, Cruz Cabrera E, Nolan BE, Ofray E, Benetti E, Visconti C, Barzaghi F, Rosenzweig SD, Lawrence MG, Sullivan KE, Yoon S, Rachimi S, Padem N, Conboy E, Stojanovic M, Petrovic G, Pasic S, Church JA, Ferdman RM, Candotti F, Arlabosse T, Theodoropoulou K, Dutmer CM, Maródi L, Szücs G, Broides A, Nahum A, Levy J, Kettunen KM, Daddali R Ravi, Seppänen MRJ, Vänttinen M, Martelius T, Grönholm J, Peri M, Azzari C, Ricci S, Ojaimi S, Edwards ES, van Zelm MC, Sun J, Abolhassani H, Pan-Hammarström Q, Hakonarson H, Mayr D, Boztug K, Boisson B, Casanova JL, Le Coz C, Poon GMK, Romberg N. Blood. 2025 Jan 24; 2025 Jan 24. PMID: 39854693.
Vascular endothelial cells derived from transgene-free pig induced pluripotent stem cells for vascular tissue engineering.Batty L, Park J, Qin L, Riaz M, Lin Y, Xu Z, Gao X, Li X, Lopez C, Zhang W, Hoareau M, Fallon ME, Huang Y, Luo H, Luo J, Ménoret S, Li P, Jiang Z, Smith P, Sachs DH, Tellides G, Ignacio Anegon, Pober JS, Liu P, Qyang Y. Acta Biomater. 2025 Jan 24; 2024 Dec 15. PMID: 39681154.
Drosophila Modulo is essential for transposon silencing and developmental robustness.Parikh RY, Nayak D, Lin H, Gangaraju VK. J Biol Chem. 2025 Jan 22; 2025 Jan 22. PMID: 39848495.
Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy.Zhang F, Chow RD, He E, Dong C, Xin S, Mirza D, Feng Y, Tian X, Verma N, Majety M, Zhang Y, Wang G, Chen S. Nat Biotechnol. 2025 Jan 16; 2025 Jan 16. PMID: 39820813.
Reply.Zhao JJ, Sundar R. Gastroenterology. 2025 Jan 15; 2025 Jan 15. PMID: 39824393.
A Novel Targeted Long-read Sequencing Approach Boosts Transcriptomic Profiling.Tian X, Fan R. Genomics Proteomics Bioinformatics. 2025 Jan 15. PMID: 39724297.
Randomized Phase III SIERRA Trial of (131)I-Apamistamab Before Allogeneic Hematopoietic Cell Transplantation Versus Conventional Care for Relapsed/Refractory AML.Gyurkocza B, Nath R, Seropian S, Choe H, Litzow MR, Abboud C, Koshy N, Stiff P, Tomlinson B, Abhyankar S, Foran J, Hari P, Chen G, Al-Kadhimi Z, Kebriaei P, Sabloff M, Orozco JJ, Jamieson K, Silverman M, Van Besien K, Schuster M, Law AD, Larkin K, Pandit-Taskar N, Rowley SD, Munshi P, Cook R, Levy MY, Lazarus HM, Sandmaier BM, Pagel JM, Reddy V, MacDougall J, McNamara K, Spross J, Haeuber E, Vusirikala M, Nahar A, Desai A, Giralt S. J Clin Oncol. 2025 Jan 10; 2024 Sep 19. PMID: 39298738.
Piwi regulates the usage of alternative transcription start sites in the Drosophila ovary.Chen J, Liu N, Qi H, Neuenkirchen N, Huang Y, Lin H. Nucleic Acids Res. 2025 Jan 7. PMID: 39657757.
METTL3 modulates colonic epithelium integrity via maintaining the self-renewal and differentiation of Lgr5+ stem cell.Ding C, Yang X, Liu H, Roulis M, Chen H, Chen Y, Xu H, Gao Y, Zhong J, Li HB, Ye Y, Cai W, Hu W, Wang Z. J Mol Cell Biol. 2025 Jan 6; 2025 Jan 6. PMID: 39762134.
STAT1 regulates immune-mediated intestinal stem cell proliferation and epithelial regeneration.Takashima S, Sharma R, Chang W, Calafiore M, Fu YY, Jansen SA, Ito T, Egorova A, Kuttiyara J, Arnhold V, Sharrock J, Santosa E, Chaudhary O, Geiger H, Iwasaki H, Liu C, Sun J, Robine N, Mazutis L, Lindemans CA, Hanash AM. Nat Commun. 2025 Jan 2; 2025 Jan 2. PMID: 39746933.
Fully biologic endothelialized-tissue-engineered vascular conduits provide antithrombotic function and graft patency.Park J, Riaz M, Qin L, Zhang W, Batty L, Fooladi S, Kural MH, Li X, Luo H, Xu Z, Wang J, Banno K, Gu SX, Yuan Y, Anderson CW, Ellis MW, Zhou J, Luo J, Shi X, Shin JH, Liu Y, Lee S, Yoder MC, Elder RW, Mak M, Thorn S, Sinusas A, Gruber PJ, Hwa J, Tellides G, Niklason LE, Qyang Y. Cell Stem Cell. 2025 Jan 2; 2024 Dec 6. PMID: 39644899.
Biodistribution of Polymeric Nanoparticles following in utero Delivery to a Nonhuman Primate.Eaton DA, Lynn AY, Surprenant JM, Deschenes EI, Guerra ME, Rivero R, Yung NK, O'Connor M, Glazer PM, Bahtiyar MO, Saltzman WM, Stitelman DH. Biomed Hub. 2025 Jan-Dec; 2024 Dec 12. PMID: 39845408.
Biology of Hox Genes: Questions and Technological Challenges.Parambil SA, De Kumar B. Methods Mol Biol. 2025. PMID: 39745601.
Author Correction: π-HuB: the proteomic navigator of the human body.He F, Aebersold R, Baker MS, Bian X, Bo X, Chan DW, Chang C, Chen L, Chen X, Chen YJ, Cheng H, Collins BC, Corrales F, Cox J, E W, Van Eyk JE, Fan J, Faridi P, Figeys D, Gao GF, Gao W, Gao ZH, Goda K, Goh WWB, Gu D, Guo C, Guo T, He Y, Heck AJR, Hermjakob H, Hunter T, Iyer NG, Jiang Y, Jimenez CR, Joshi L, Kelleher NL, Li M, Li Y, Lin Q, Liu CH, Liu F, Liu GH, Liu Y, Liu Z, Low TY, Lu B, Mann M, Meng A, Moritz RL, Nice E, Ning G, Omenn GS, Overall CM, Palmisano G, Peng Y, Pineau C, Poon TCW, Purcell AW, Qiao J, Reddel RR, Robinson PJ, Roncada P, Sander C, Sha J, Song E, Srivastava S, Sun A, Sze SK, Tang C, Tang L, Tian R, Vizcaíno JA, Wang C, Wang C, Wang X, Wang X, Wang Y, Weiss T, Wilhelm M, Winkler R, Wollscheid B, Wong L, Xie L, Xie W, Xu T, Xu T, Yan L, Yang J, Yang X, Yates J, Yun T, Zhai Q, Zhang B, Zhang H, Zhang L, Zhang L, Zhang P, Zhang Y, Zheng YZ, Zhong Q, Zhu Y. Nature. 2025 Jan. PMID: 39715925.
Author Correction: Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain.Marsh SE, Walker AJ, Kamath T, Dissing-Olesen L, Hammond TR, de Soysa TY, Young AMH, Murphy S, Abdulraouf A, Nadaf N, Dufort C, Walker AC, Lucca LE, Kozareva V, Vanderburg C, Hong S, Bulstrode H, Hutchinson PJ, Gaffney DJ, Hafler DA, Franklin RJM, Macosko EZ, Stevens B. Nat Neurosci. 2025 Jan. PMID: 39672966.
Author Correction: Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression.Seah C, Breen MS, Rusielewicz T, Bader HN, Xu C, Hunter CJ, McCarthy B, Deans PJM, Chattopadhyay M, Goldberg J, Dobariya S, Desarnaud F, Makotkine I, Flory JD, Bierer LM, Staniskyte M, Noggle SA, Huckins LM, Paull D, Brennand KJ, Yehuda R. Nat Neurosci. 2025 Jan. PMID: 39633181.
Dysregulation in keratinocytes drives systemic lupus erythematosus onset.Tian J, Shi L, Zhang D, Yao X, Zhao M, Kumari S, Lu J, Yu D, Lu Q. Cell Mol Immunol. 2025 Jan; 2024 Dec 3. PMID: 39627610.
A multiomic atlas identifies a treatment-resistant, bone marrow progenitor-like cell population in T cell acute lymphoblastic leukemia.Xu J, Chen C, Sussman JH, Yoshimura S, Vincent T, Pölönen P, Hu J, Bandyopadhyay S, Elghawy O, Yu W, Tumulty J, Chen CH, Li EY, Diorio C, Shraim R, Newman H, Uppuluri L, Li A, Chen GM, Wu DW, Ding YY, Xu JA, Karanfilovski D, Lim T, Hsu M, Thadi A, Ahn KJ, Wu CY, Peng J, Sun Y, Wang A, Mehta R, Frank D, Meyer L, Loh ML, Raetz EA, Chen Z, Wood BL, Devidas M, Dunsmore KP, Winter SS, Chang TC, Wu G, Pounds SB, Zhang NR, Carroll W, Hunger SP, Bernt K, Yang JJ, Mullighan CG, Tan K, Teachey DT. Nat Cancer. 2025 Jan; 2024 Nov 25. PMID: 39587259.
Human HDAC6 senses valine abundancy to regulate DNA damage.Jin J, Meng T, Yu Y, Wu S, Jiao CC, Song S, Li YX, Zhang Y, Zhao YY, Li X, Wang Z, Liu YF, Huang R, Qin J, Chen Y, Cao H, Tan X, Ge X, Jiang C, Xue J, Yuan J, Wu D, Wu W, Jiang CZ, Wang P. Nature. 2025 Jan; 2024 Nov 20. PMID: 39567688.
GPR68 supports AML cells through the calcium/calcineurin pro-survival pathway and confers chemoresistance by mediating glucose metabolic symbiosis.He X, Hawkins C, Lawley L, Phan TM, Park I, Joven N, Zhang J, Wunderlich M, Mizukawa B, Pei S, Patel A, VanOudenhove J, Halene S, Fang J. Biochim Biophys Acta Mol Basis Dis. 2025 Jan; 2024 Nov 8. PMID: 39522891.
Pre-emptive therapeutic decisions based on measurable residual disease status in acute myeloid leukemia: ready for prime time?El Chaer F, Perissinotti AJ, Loghavi S, Zeidan AM. Leukemia. 2025 Jan; 2024 Nov 5. PMID: 39496917.
Incidence of bacterial blood stream infections in patients with acute GVHD.Wallis W, Gulbis AM, Wang T, Lee CJ, Sharma A, Williams KM, Nishihori T, Prestidge T, Gowda L, Byrne M, Krem MM, MacMillan ML, Kitko CL, Pidala J, Spellman SR, Lee SJ, Alousi AM. Bone Marrow Transplant. 2025 Jan; 2024 Oct 18. PMID: 39420192.
DNA methylation in mammalian development and disease.Smith ZD, Hetzel S, Meissner A. Nat Rev Genet. 2025 Jan; 2024 Aug 12. PMID: 39134824.
NaP-TRAP reveals the regulatory grammar in 5'UTR-mediated translation regulation during zebrafish development.Strayer EC, Krishna S, Lee H, Vejnar C, Neuenkirchen N, Gupta A, Beaudoin JD, Giraldez AJ. Nat Commun. 2024 Dec 30; 2024 Dec 30. PMID: 39738051.
Transition to Enteral Triazole Antifungal Therapy for Pediatric Invasive Candidiasis: Secondary Analysis of a Multicenter Cohort Study Conducted by the Pediatric Fungal Network.Bucayu RFT, Boge CLK, Yildirim I, Avilés-Robles M, Vora SB, Berman DM, Sharma TS, Sung L, Castagnola E, Palazzi DL, Danziger-Isakov L, Yin DE, Roilides E, Maron G, Tribble AC, Soler-Palacin P, López-Medina E, Romero J, Belani K, Arrieta AC, Carlesse F, Nolt D, Halasa N, Dulek D, Rajan S, Muller WJ, Ardura MI, Pong A, Gonzalez BE, Salvatore CM, Huppler AR, Aftandilian C, Abzug MJ, Chakrabarti A, Green M, Lutsar I, Knackstedt ED, Johnson SK, Steinbach WJ, Fisher BT, Wattier RL. J Pediatric Infect Dis Soc. 2024 Dec 30. PMID: 39513400.
Cataloguing the postnatal small intestinal transcriptome during the first postnatal month.Oliveira LFS, Khetani RS, Wu YS, Dasuri VS, Harrington AW, Olaloye O, Goldsmith J, Breault DT, Konnikova L, Ho Sui SJ, O'Connell AE. bioRxiv. 2024 Dec 27; 2024 Dec 27. PMID: 39386454.
sc-SPLASH provides ultra-efficient reference-free discovery in barcoded single-cell sequencing.Dehghannasiri R, Kokot M, Starr AL, Maziarz J, Gordon T, Tan SY, Wang PL, Voskoboynik A, Musser JM, Deorowicz S, Salzman J. bioRxiv. 2024 Dec 24; 2024 Dec 24. PMID: 39763839.
Haplotype editing with CRISPR/Cas9 as a therapeutic approach for dominant-negative missense mutations in NEFL.Dua PH, Simon BMJ, Marley CBE, Feliciano CM, Watry HL, Steury D, Abraham A, Gilbertson EN, Ramey GD, Capra JA, Conklin BR, Judge LM. bioRxiv. 2024 Dec 22; 2024 Dec 22. PMID: 39763989.
Protocol for detecting glycoRNAs using metabolic labeling and northwestern blot.Li L, Zhang N, Pantoja C, Wang Y, Lu J. STAR Protoc. 2024 Dec 20; 2024 Sep 19. PMID: 39298321.
Hyperactive PLCG1 drives non-canonical signaling to promote cell survival.Zeng L, Zhang X, Xiong Y, Sato K, Hajicek N, Sondek J, Su X. bioRxiv. 2024 Dec 18; 2024 Dec 18. PMID: 39763946.
Genetic Analysis of Epidermal Inclusion Cysts Reveals NEK9 Variants as a Common Driver of Comedogenesis and Cyst Formation.Ellis KT, Myung P, Cohen J, Choate KA. J Invest Dermatol. 2024 Dec 18; 2024 Dec 18. PMID: 39706256.
Scaling deep identifiable models enables zero-shot characterization of single-cell biological states.Dong M, Agrawal K, Fan R, Sefik E, Flavell RA, Kluger Y. bioRxiv. 2024 Dec 18; 2024 Dec 18. PMID: 38014345.
Mesenchymal Stem Cells and Their Extracellular Vesicles: Therapeutic Mechanisms for Blood-Spinal Cord Barrier Repair Following Spinal Cord Injury.Nakazaki M, Yokoyama T, Lankford KL, Hirota R, Kocsis JD, Honmou O. Int J Mol Sci. 2024 Dec 16; 2024 Dec 16. PMID: 39769223.
De novo variants disrupt an LDB1-regulated transcriptional network in congenital ventriculomegaly.Allington G, Mehta NH, Dennis E, Mekbib KY, Reeves B, Kiziltug E, Chen S, Zhao S, Duy PQ, Saleh M, Ang LC, Fan B, Nelson-Williams C, Moreno-de-Luca A, Haider S, Lifton RP, Alper SL, McGee S, Jin SC, Kahle KT. Brain. 2024 Dec 16; 2024 Dec 16. PMID: 39680505.
Distinct mechanisms drive divergent phenotypes in hypertrophic and dilated cardiomyopathy-associated TPM1 variants.Halder SS, Rynkiewicz MJ, Kim L, Barry ME, Zied AG, Sewanan LR, Kirk JA, Moore JR, Lehman WJ, Campbell SG. J Clin Invest. 2024 Dec 16; 2024 Dec 16. PMID: 39436707.
H3.1K27M-induced misregulation of the TSK/TONSL-H3.1 pathway causes genomic instability.Yuan W, Huang YC, LeBlanc C, Poulet A, Valsakumar D, van Wolfswinkel JC, Voigt P, Jacob Y. bioRxiv. 2024 Dec 11; 2024 Dec 11. PMID: 39713323.
Integration of Imaging-based and Sequencing-based Spatial Omics Mapping on the Same Tissue Section via DBiTplus.Enninful A, Zhang Z, Klymyshyn D, Zong H, Bai Z, Farzad N, Su G, Baysoy A, Nam J, Yang M, Lu Y, Zhang NR, Braubach O, Xu ML, Ma Z, Fan R. Res Sq. 2024 Dec 11; 2024 Dec 11. PMID: 39711562.
High-Throughput Quantification of miRNA-3'-Untranslated-Region Regulatory Effects.Mastriano S, Kanoria S, Rennie W, Liu C, Li D, Cheng J, Ding Y, Lu J. bioRxiv. 2024 Dec 6; 2024 Dec 6. PMID: 39677669.
Sickle cell disease in India: the journey and hope for the future.Gupta K, Krishnamurti L, Jain D. Hematology Am Soc Hematol Educ Program. 2024 Dec 6. PMID: 39644008.