Robert Kleven, PhD, MD
Hospital ResidentCards
About
Research
Publications
2025
Percutaneous Radiologic Gastrostomy Tube Placement Techniques
Kleven R, Ikeda I, Cornman-Homonoff J. Percutaneous Radiologic Gastrostomy Tube Placement Techniques. Seminars In Interventional Radiology 2025, 42: 009-016. PMID: 40342381, PMCID: PMC12058293, DOI: 10.1055/s-0045-1806797.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPercutaneous Radiologic Gastrostomy Placement in Challenging Clinical Scenarios
Ikeda I, Kleven R, Cornman-Homonoff J. Percutaneous Radiologic Gastrostomy Placement in Challenging Clinical Scenarios. Seminars In Interventional Radiology 2025, 42: 017-021. PMID: 40342380, PMCID: PMC12058298, DOI: 10.1055/s-0045-1805046.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2022
Effect of Recombinant Tissue Plasminogen Activator and 120-kHz Ultrasound on Porcine Intracranial Thrombus Density
Kleven R, Huang S, Ford S, Sakthivel K, Thomas S, Zuccarello M, Herr A, Holland C. Effect of Recombinant Tissue Plasminogen Activator and 120-kHz Ultrasound on Porcine Intracranial Thrombus Density. Ultrasound In Medicine & Biology 2022, 49: 539-548. PMID: 36336551, PMCID: PMC13456300, DOI: 10.1016/j.ultrasmedbio.2022.10.006.Peer-Reviewed Original Research
2021
Accelerated sonothrombolysis with Definity in a xenographic porcine cerebral thromboembolism model
Kleven R, Karani K, Hilvert N, Ford S, Mercado-Shekhar K, Racadio J, Rao M, Abruzzo T, Holland C. Accelerated sonothrombolysis with Definity in a xenographic porcine cerebral thromboembolism model. Scientific Reports 2021, 11: 3987. PMID: 33597659, PMCID: PMC7889614, DOI: 10.1038/s41598-021-83442-3.Peer-Reviewed Original Research
2020
Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery
Kooiman K, Roovers S, Langeveld S, Kleven R, Dewitte H, O'Reilly M, Escoffre J, Bouakaz A, Verweij M, Hynynen K, Lentacker I, Stride E, Holland C. Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery. Ultrasound In Medicine & Biology 2020, 46: 1296-1325. PMID: 32165014, PMCID: PMC7189181, DOI: 10.1016/j.ultrasmedbio.2020.01.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2019
The effect of 220 kHz insonation scheme on rt-PA thrombolytic efficacy in vitro
Kleven R, Karani K, Salido N, Shekhar H, Haworth K, Mast T, Tadesse D, Holland C. The effect of 220 kHz insonation scheme on rt-PA thrombolytic efficacy in vitro. Physics In Medicine And Biology 2019, 64: 165015-165015. PMID: 31189149, PMCID: PMC8102059, DOI: 10.1088/1361-6560/ab293b.Peer-Reviewed Original ResearchIn vitro characterization of sonothrombolysis and echocontrast agents to treat ischemic stroke
Shekhar H, Kleven R, Peng T, Palaniappan A, Karani K, Huang S, McPherson D, Holland C. In vitro characterization of sonothrombolysis and echocontrast agents to treat ischemic stroke. Scientific Reports 2019, 9: 9902. PMID: 31289285, PMCID: PMC6616381, DOI: 10.1038/s41598-019-46112-z.Peer-Reviewed Original ResearchErratum to ‘Effect of clot stiffness on recombinant tissue plasminogen activator lytic susceptibility in vitro’ [Ultrasound Med Biol 44 (2018) 2710-2727]
Mercado-Shekhar K, Kleven R, Rivera H, Lewis R, Karani K, Vos H, Abruzzo T, Haworth K, Holland C. Erratum to ‘Effect of clot stiffness on recombinant tissue plasminogen activator lytic susceptibility in vitro’ [Ultrasound Med Biol 44 (2018) 2710-2727]. Ultrasound In Medicine & Biology 2019, 45: 1860. PMID: 31053428, PMCID: PMC6599611, DOI: 10.1016/j.ultrasmedbio.2019.04.013.Commentaries, Editorials and Letters
2018
Effect of Clot Stiffness on Recombinant Tissue Plasminogen Activator Lytic Susceptibility in Vitro
Mercado-Shekhar K, Kleven R, Rivera H, Lewis R, Karani K, Vos H, Abruzzo T, Haworth K, Holland C. Effect of Clot Stiffness on Recombinant Tissue Plasminogen Activator Lytic Susceptibility in Vitro. Ultrasound In Medicine & Biology 2018, 44: 2710-2727. PMID: 30268531, PMCID: PMC6551517, DOI: 10.1016/j.ultrasmedbio.2018.08.005.Peer-Reviewed Original ResearchClot stiffness is inversely correlated with rt-PA thrombolytic efficacy in vitro
Mercado-Shekhar K, Kleven R, Rivera H, Lewis R, Karani K, Vos H, Abruzzo T, Haworth K, Holland C. Clot stiffness is inversely correlated with rt-PA thrombolytic efficacy in vitro. The Journal Of The Acoustical Society Of America 2018, 143: 1928-1928. DOI: 10.1121/1.5036298.Peer-Reviewed Original Research
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