Breast Imaging
Specialized physicians comprise the Yale Breast Imaging Division, devoted to state-of-the-art breast imaging and diagnosis. As a comprehensive breast center, radiologist physicians and staff are each highly specialized which allows us to offer the best care possible. Our team works closely with breast surgeons, oncologists and pathologists, providing multi-disciplinary care.
Clinical Interests
The Yale Breast Imaging physicians are experts in screening and diagnostic mammography, ultrasound, 3T MRI and interventional procedures such as pre-operative needle localization plus stereotactic, US, and MR core biopsy.
The Yale Breast Imaging home base is located at Smilow Cancer Hospital and the Yale School of Medicine, but there are also eight additional offices located in New Haven and Fairfield counties. Each office provides state-of-the-art equipment and radiologist physicians focused on breast imaging. As a high volume division, we care for women throughout Connecticut. By serving also as a referral center for complicated cases, many women who seek specialized care after a new cancer diagnosis seek our expertise.
Section's Statistics (per year)
Total | Type |
---|---|
95,000 | Total studies |
60,000 | Screening Mammograms |
11,000 | Diagnostic Exams |
30,000 | Breast Ultrasounds |
3,000 | Procedures |
1,800 | MRI |
Research Directions
- Breast cancer screening, including high risk screening and screening breast ultrasound
- Digital breast tomosynthesis
- Breast ultrasound
- Breast MR
- Artificial Intelligence
- Breast biopsy improvements
- Best practices to optimize patient care
The Yale Breast Imaging physicians are nationally and internationally recognized radiology leaders in breast imaging, who publish regularly in high impact, prestigious peer-reviewed medical journals, while also lecturing at radiology meetings worldwide.
Education
The Breast Imaging Division is an integral part of the Yale-New Haven Breast Center at Yale-New Haven Hospital. In addition to teaching Yale Medical students and Diagnostic Radiology residents, our Division hosts two Breast Imaging fellowships each year. For more information regarding the Yale Breast Imaging Fellowship, click here.
Community and Global Outreach
Members of our Breast Imaging Division regularly participate in community outreach, to inform women throughout Connecticut via talks and gatherings at local libraries, schools, women’s clubs and other venues.
The Division also actively participates in Rad-Aid, whose mission is to help improve breast cancer outcomes and survival in low and middle-income countries. Recently, Yale Breast Imaging conducted assessments of breast imaging needs at the two main teaching hospitals in Ghana, and is exploring opportunities for virtual learning/teaching during the pandemic.
Leadership
Eastern Division Section Chief
- Office
- Appt
- Clinic Fax
Western Division Section Chief
- Office
- Appt
- Clinic Fax
Publications
2025
213 Focal Atypical Ductal Hyperplasia (ADH) Upgrade Rate with Radiological Correlation: A Single Institution Study
Podany P, Kahila M, Proussaloglou E, Lewin J, Andrejeva L, Krishnamurti U. 213 Focal Atypical Ductal Hyperplasia (ADH) Upgrade Rate with Radiological Correlation: A Single Institution Study. Laboratory Investigation 2025, 105: 102437. DOI: 10.1016/j.labinv.2024.102437.Peer-Reviewed Original ResearchEditorial Comment: Nonmass Lesions on Breast Ultrasound-Emerging Characteristics and Challenges.
Philpotts L. Editorial Comment: Nonmass Lesions on Breast Ultrasound-Emerging Characteristics and Challenges. American Journal Of Roentgenology 2025, 224: e2432572. PMID: 39772588, DOI: 10.2214/ajr.24.32572.Peer-Reviewed Original Research
2024
Complex Cystic and Solid Masses
Harigopal M, Cole K, Podany P, Verma A, Andrejeva L. Complex Cystic and Solid Masses. 2024, 57-95. DOI: 10.1007/978-3-031-65711-5_3.Peer-Reviewed Original ResearchConceptsCystic lesionsSolid massAspiration of cystsBenign papillary tumorsPapillary apocrine metaplasiaCore needle biopsyComplex cystic lesionsMalignant cystic lesionsPresence of calcificationLeakage of cyst contentsFindingsThe vast majorityPapillary tumorsApocrine carcinomaPapillary carcinomaDuctal carcinomaNipple dischargeCystic componentNeedle biopsyApocrine metaplasiaDuct ectasiaBenign lesionsReactive lesionsComplicated cystsPerimenopausal womenFat necrosisDiscordances Between Radiology and Pathology
Harigopal M, Verma A, Andrejeva L, Lewin J. Discordances Between Radiology and Pathology. 2024, 375-391. DOI: 10.1007/978-3-031-65711-5_14.Peer-Reviewed Original ResearchConceptsPathological findingsImaging characteristicsMRI-guided biopsyFalse-negative diagnosesRadiology-pathology correlationH&E levelsPreoperative biopsyStereotactic biopsySurgical excisionPercutaneous biopsyDiscordant casesSonographic guidanceBreast biopsyAncillary stainsHistopathological findingsBiopsyMammographic lesionsLesionsIndividual pathologistsPathologistsPotential causesUltrasoundWeekly conferencesImage featuresDiscordanceCircumscribed Masses
Harigopal M, Raghu M, Pham R, Rende A, Podany P, Andrejeva L. Circumscribed Masses. 2024, 11-55. DOI: 10.1007/978-3-031-65711-5_2.Peer-Reviewed Original ResearchConceptsTerminal duct lobular unitsEncapsulated papillary carcinomaInvasive ductal carcinomaCircumscribed massFibroepithelial neoplasmsStromal componentsScreening mammographyPhyllodes tumorFibroepithelial lesionsPapillary carcinomaDuctal carcinomaInvasive carcinomaComplicated cystsCellular fibroadenomaHigh-grade invasive ductal carcinomaBI-RADSDuctal carcinoma in situOuter layer of myoepithelial cellsAggressive breast malignancyBasal-like carcinomasBenign fibroepithelial lesionsBenign fibroepithelial neoplasmBorderline phyllodes tumorMalignant phyllodes tumorSmooth muscle metaplasiaSpiculated Masses
Harigopal M, Andrejeva L, Lanjewar S, Podany P. Spiculated Masses. 2024, 127-158. DOI: 10.1007/978-3-031-65711-5_5.Peer-Reviewed Original ResearchConceptsInvasive ductal carcinomaInvasive lobular carcinomaDuctal carcinoma in situLobular carcinomaDuctal carcinomaSpiculated massesTumor cellsBenign entitySclerosing adenosisCorrelation of imaging findingsDesmoplastic stromal responseDiscohesive tumor cellsCore needle biopsyPseudoangiomatous stromal hyperplasiaCarcinoma in situInvasive mammary carcinomaFalse-negative mammogramsGranular cell tumorInvasive tumor cellsDiabetic mastopathyMucinous carcinomaStromal hyperplasiaInvasive cancerPleomorphic calcificationsDesmoplastic stromaIntroduction and General Consideration of Radiology-Pathology Correlation
Harigopal M, Andrejeva L, Podany P, Lewin J, Raghu M, Singh K. Introduction and General Consideration of Radiology-Pathology Correlation. 2024, 1-9. DOI: 10.1007/978-3-031-65711-5_1.Peer-Reviewed Original ResearchConceptsFull-field digital mammographyInterval cancer rateIncreased cancer detection ratesCancer detection rateScreen-film mammographyCancer ratesBreast pathologistsYears of experiencePatient careNational expertsMultidisciplinary meetingComplex exerciseCore needle biopsyDiagnosis of breast lesionsDigital mammographyMammographyField of radiologyRadiology-pathology correlationTissue samplesRadiology reportsBreastAccurate diagnosis of breast lesionsCharacterization of lesionsBreast tissue samplesBreast imagingArchitectural Distortions
Butler R, Durand M, Lanjevar S, Podany P, Andrejeva L, Harigopal M. Architectural Distortions. 2024, 185-207. DOI: 10.1007/978-3-031-65711-5_7.Peer-Reviewed Original ResearchConceptsInvasive lobular carcinomaLikelihood of malignancyRadial sclerosing lesionsLobular carcinomaSclerosing lesionsTubular carcinomaArchitectural distortionBenign entityDegree of proliferative changeRadial scar/complex sclerosing lesionDuctal carcinoma in situCarcinoma in situInvasive ductal carcinomaChance of malignancyIncidental microscopic findingAbsence of enhancementPost-contrast imagesMyoepithelial cell layerEntrapped glandsField digital mammographyDiscohesive cellsSonographic correlateDuctal carcinomaInvasive carcinomaPalpable massMasses with Indistinct Margins
Singh K, Lee J, Harigopal M, Andrejeva L. Masses with Indistinct Margins. 2024, 97-125. DOI: 10.1007/978-3-031-65711-5_4.Peer-Reviewed Original ResearchSkin Thickening and Vascular Lesions
Andrejeva L, Lanjewar S, Woolf G, Killelea B, Brownson K, Podany P, Harigopal M. Skin Thickening and Vascular Lesions. 2024, 297-323. DOI: 10.1007/978-3-031-65711-5_11.Peer-Reviewed Original ResearchConceptsRare group of neoplasmsInflammatory breast carcinomaInvasive lobular carcinomaMalignant vascular tumorsGroup of neoplasmsIll-defined marginsLobular carcinomaBreast carcinomaBenign tumorsClinical presentationBenign lesionsVascular tumorsBreast parenchymaClinical historyWell-circumscribedSkin thickeningMalignant processVascular lesionsRare groupImaging appearanceSubcutaneous tissueContrast enhancementBreastCarcinomaTumorCalcifications
Singh K, Sheiman L, Killelea B, Brownson K, Andrejeva L. Calcifications. 2024, 209-233. DOI: 10.1007/978-3-031-65711-5_8.Peer-Reviewed Original ResearchConceptsPost-biopsy mammogramGroups of calcificationsDistribution of calcificationHistological sectionsBreast tissueTarget calcificationMagnification viewsBreast imagingNeoplastic epithelial proliferationCore needle biopsyStereotactic core biopsyTissue levelsRad-path correlationH&E-stained sectionsMilk of calciumAssociation of calcificationMammographic guidanceAmount of calcificationBiopsy planningCore biopsyNeedle biopsyDiagnostic dilemmaBiopsy siteDilated ductsEpithelial proliferationMRI Breast Findings
Narasimhamurthy M, O’Brien S, Andrejeva L, Nayak A. MRI Breast Findings. 2024, 235-267. DOI: 10.1007/978-3-031-65711-5_9.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingNon-mass enhancementBreast lesionsBreast magnetic resonance imagingPracticing pathologistsMagnetic resonance imaging findingsRadiologic-pathologic correlationBreast core biopsiesMalignant breast lesionsDiagnosing breast lesionsCore biopsyMRI findingsBreast biopsyImaging examinationsFalse-positive rateBiopsyResonance imagingLesionsBreastImaging techniquesPathologistsImage patternsLesions of Nipple and Axilla
Andrejeva L, Venkateswaran J, Vidhun R, Killelea B, Brownson K, Singh K. Lesions of Nipple and Axilla. 2024, 269-295. DOI: 10.1007/978-3-031-65711-5_10.Peer-Reviewed Original ResearchConceptsSquamous metaplasia of lactiferous ductsMammary duct ectasiaIntraductal papillomaSubareolar tissueDuct ectasiaMalignant lesionsNipple adenomaSubareolar ductsCase of incomplete excisionPaget's diseaseMammographically occult malignanciesBenign epithelial lesionsIntraductal epithelial proliferationRisk of recurrenceTreatment of choicePeriareolar regionOccult malignancyNegative marginsIncomplete excisionSurgical excisionSyringomatous adenomaBreast carcinomaInvasive carcinomaNegative mammogramEpithelial lesionsFocal and Developing Asymmetries
Tamayo S, Andrejeva L, Singh K. Focal and Developing Asymmetries. 2024, 159-184. DOI: 10.1007/978-3-031-65711-5_6.Peer-Reviewed Original ResearchConceptsFocal asymmetryBreast cancerBreast tissueBenign breast tissueFibroglandular tissue densityLikelihood of malignancyComparison mammogramsFibroadenomatoid changeMalignant causesBaseline mammogramMammographic findingsBenign causesSonographic abnormalitiesNon-palpableFat necrosisImaging findingsScreening mammographyArchitectural distortionPosttreatment changesMammographic viewsBreastMalignancyTissue densityCancerMammogramsRare Breast Tumors
Harigopal M, Podany P, Andrejeva L, Singh K. Rare Breast Tumors. 2024, 343-374. DOI: 10.1007/978-3-031-65711-5_13.Peer-Reviewed Original ResearchCitationsConceptsSubtypes of breast cancerBreast cancerRare subtypeWorld Health OrganizationRare subtype of breast cancerHistological subtype of breast cancerWorld Health Organization Classification of TumorsCore needle biopsy specimensWorld Health Organization classificationTall cell carcinomaNeedle biopsy specimensRare histologic typeClassification of tumorsRare cancer typesRare tumorHistological subtypesHistological typeCell carcinomaUnusual subtypeBiopsy specimensPrognostic implicationsGenetic alterationsHistological featuresHistologic cluesAncillary testsBreast Cancers Detected during a Decade of Screening with Digital Breast Tomosynthesis: Comparison with Digital Mammography.
Philpotts L, Grewal J, Horvath L, Giwerc M, Staib L, Etesami M. Breast Cancers Detected during a Decade of Screening with Digital Breast Tomosynthesis: Comparison with Digital Mammography. Radiology 2024, 312: e232841. PMID: 39287520, DOI: 10.1148/radiol.232841.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsDigital breast tomosynthesisBreast cancerDigital mammographyAdvanced cancerHuman epidermal growth factor 2-positiveOverdiagnosis of breast cancerProportion of advanced cancersBreast cancer detection rateEffectiveness of digital breast tomosynthesisRate of advanced cancerDuctal carcinoma in situInterval cancer rateTwo-dimensional digital mammographyInvasive cancer sizeTriple-negative tumorsCancer detection rateCarcinoma in situBreast tomosynthesisFalse-negative findingsIncreased cancer detectionIncident screensIncident roundsAxillary nodesDM screeningInvasive cancerCancer Metrics on Subsequent Screening Rounds: Another Piece in the Complicated Puzzle.
Hooley R, Philpotts L. Cancer Metrics on Subsequent Screening Rounds: Another Piece in the Complicated Puzzle. Radiology 2024, 312: e241540. PMID: 39078301, DOI: 10.1148/radiol.241540.Peer-Reviewed Original ResearchSIFT-DBT: Self-Supervised Initialization and Fine-Tuning for Imbalanced Digital Breast Tomosynthesis Image Classification
Du Y, Hooley R, Lewin J, Dvornek N. SIFT-DBT: Self-Supervised Initialization and Fine-Tuning for Imbalanced Digital Breast Tomosynthesis Image Classification. 2011 IEEE International Symposium On Biomedical Imaging: From Nano To Macro 2024, 00: 1-5. PMID: 39263046, PMCID: PMC11386909, DOI: 10.1109/isbi56570.2024.10635723.Peer-Reviewed Original ResearchMultimodality Imaging of Postmastectomy Breast Reconstruction Techniques, Complications, and Tumor Recurrence.
Thai J, Sodagari F, Colwell A, Winograd J, Revzin M, Mahmoud H, Mozayan S, Chou S, Destounis S, Butler R. Multimodality Imaging of Postmastectomy Breast Reconstruction Techniques, Complications, and Tumor Recurrence. RadioGraphics 2024, 44: e230070. PMID: 38573814, DOI: 10.1148/rg.230070.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsTumor recurrencePostoperative evaluation of patientsFlap reconstruction methodsImplant-based reconstructionMultimodal imagingBreast reconstruction techniquesFat graft placementBreast cancer recurrenceTissue flap reconstructionEvaluation of patientsNipple-sparing techniquesTissue donor sitesFlap-based reconstructionNipple-areolar complex reconstructionDiagnostic breast imagingUnique patient populationAutologous tissue flapsAbnormal imaging appearancesBreast cancer screeningMastectomy optionLocal recurrenceOncoplastic surgeryDisease recurrenceFlap reconstructionReconstructed breastEarly Childhood Education Tools: Organizations, Periodicals, and Databases
Sheiman J, Sheiman L. Early Childhood Education Tools: Organizations, Periodicals, and Databases. 2024, 483-503. DOI: 10.4324/9781315058047-57.Peer-Reviewed Original ResearchCorrection to: Radiology Pathology Correlations of Breast Lesions
Harigopal M, Andrejeva L, Singh K, Lewin J. Correction to: Radiology Pathology Correlations of Breast Lesions. 2024, c1-c1. DOI: 10.1007/978-3-031-65711-5_15.Peer-Reviewed Original Research
2023
Editorial Comment: Artificial Intelligence May Help Define Screening Strategies in Patients With Dense Breasts.
Butler R. Editorial Comment: Artificial Intelligence May Help Define Screening Strategies in Patients With Dense Breasts. American Journal Of Roentgenology 2023, 222: e2330042. PMID: 37556603, DOI: 10.2214/ajr.23.30042.Peer-Reviewed Original ResearchPACS-integrated machine learning breast density classifier: clinical validation
Lewin J, Schoenherr S, Seebass M, Lin M, Philpotts L, Etesami M, Butler R, Durand M, Heller S, Heacock L, Moy L, Tocino I, Westerhoff M. PACS-integrated machine learning breast density classifier: clinical validation. Clinical Imaging 2023, 101: 200-205. PMID: 37421715, DOI: 10.1016/j.clinimag.2023.06.023.Peer-Reviewed Original ResearchCitationsAltmetricModern Challenges in Assessing Breast Cancer Screening Strategies: A Call for Added Resources.
Hooley R, Butler R. Modern Challenges in Assessing Breast Cancer Screening Strategies: A Call for Added Resources. Radiology 2023, 306: e230145. PMID: 36749216, DOI: 10.1148/radiol.230145.Peer-Reviewed Original ResearchCitationsAltmetric
2022
Optoacoustic Imaging With Decision Support for Differentiation of Benign and Malignant Breast Masses: A 15-Reader Retrospective Study.
Seiler S, Neuschler E, Butler R, Lavin P, Dogan B. Optoacoustic Imaging With Decision Support for Differentiation of Benign and Malignant Breast Masses: A 15-Reader Retrospective Study. American Journal Of Roentgenology 2022, 220: 646-658. PMID: 36475811, DOI: 10.2214/ajr.22.28470.Peer-Reviewed Original ResearchCitationsAltmetric
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Smilow Cancer Hospital, 35 Park Street New Haven, CT 06520-8042