John Lewin, MD
Associate Professor of Radiology and Biomedical ImagingCards
About
Research
Publications
2019
Contrast-Enhanced Mammography: A Scientific Review
Lewin J, Patel B, Tanna A. Contrast-Enhanced Mammography: A Scientific Review. Journal Of Breast Imaging 2019, 2: 7-15. PMID: 38424994, DOI: 10.1093/jbi/wbz074.Peer-Reviewed Original ResearchContrast-enhanced mammographyMagnetic resonance imagingRetrospective reviewContrast-enhanced magnetic resonance imagingDiagnostic clinical settingBreast screeningProspective studyClinical useClinical utilityHigh riskResonance imagingMammographyClinical settingScreening studiesStudy to studyClinical researchPublished literatureHow to Write a Scientific Abstract for Symposium Submission
Georgian-Smith D, Leung J, Lewin J, Conant E, Zuley M. How to Write a Scientific Abstract for Symposium Submission. Journal Of Breast Imaging 2019, 1: 159-160. PMID: 38424765, DOI: 10.1093/jbi/wbz037.Peer-Reviewed Original ResearchA History of Contrast-Enhanced Mammography
Lewin J, Yaffe M. A History of Contrast-Enhanced Mammography. 2019, 1-21. DOI: 10.1007/978-3-030-11063-5_1.Peer-Reviewed Original ResearchContrast-enhanced mammographyFull-field digital mammography unitX-ray physicsDigital mammography unitDual-energy subtraction methodDual-energy contrast-enhanced mammographyMammography unitContrast imagingDual-energyDigital mammography technologiesRoutine clinical useX-rayMultiple-projectClinical useSubtraction methodBilateral imagesComparison of Contrast-Enhanced Mammography and Contrast-Enhanced Breast MRI
Patel B, Lewin J. Comparison of Contrast-Enhanced Mammography and Contrast-Enhanced Breast MRI. 2019, 77-91. DOI: 10.1007/978-3-030-11063-5_5.Peer-Reviewed Original Research
2018
Correction to: Phase 2 Open-Label Trial Investigating Percutaneous Laser Ablation for Treatment of Early-Stage Breast Cancer: MRI, Pathology, and Outcome Correlations
Schwartzberg B, Lewin J, Abdelatif O, Bernard J, Bu-Ali H, Cawthorn S, Chen-Seetoo M, Feldman S, Govindarajulu S, Jones L, Juette A, Kavia S, Maganini R, Pain S, Shere M, Shriver C, Smith S, Valencia A, Whitacre E, Whitney R. Correction to: Phase 2 Open-Label Trial Investigating Percutaneous Laser Ablation for Treatment of Early-Stage Breast Cancer: MRI, Pathology, and Outcome Correlations. Annals Of Surgical Oncology 2018, 25: 998-998. PMID: 30298314, PMCID: PMC6828100, DOI: 10.1245/s10434-018-6861-3.Peer-Reviewed Original ResearchInterstitial Laser Ablation as Alternative to Surgical Treatment of Benign Breast Tumors
Chen M, Schwartzberg B, Lewin J, Taback B, Ishtihar S, Maganini R, Mansfield W, Gardner R, Del Toro M, Dowlatshahi K. Interstitial Laser Ablation as Alternative to Surgical Treatment of Benign Breast Tumors. Journal Of The American College Of Surgeons 2018, 227: e83. DOI: 10.1016/j.jamcollsurg.2018.08.223.Peer-Reviewed Original ResearchPhase 2 Open-Label Trial Investigating Percutaneous Laser Ablation for Treatment of Early-Stage Breast Cancer: MRI, Pathology, and Outcome Correlations
Schwartzberg B, Lewin J, Abdelatif O, Bernard J, Bu-Ali H, Cawthorn S, Chen-Seetoo M, Feldman S, Govindarajulu S, Jones L, Juette A, Kavia S, Maganini R, Pain S, Shere M, Shriver C, Smith S, Valencia A, Whitacre E, Whitney R. Phase 2 Open-Label Trial Investigating Percutaneous Laser Ablation for Treatment of Early-Stage Breast Cancer: MRI, Pathology, and Outcome Correlations. Annals Of Surgical Oncology 2018, 25: 2958-2964. PMID: 29987603, PMCID: PMC6208881, DOI: 10.1245/s10434-018-6623-2.Peer-Reviewed Original ResearchConceptsInvasive ductal breast carcinomaPercutaneous laser ablationNegative predictive valueMagnetic resonance imagingPost-ablationTreated with percutaneous laser ablationTreatment of early-stage breast cancerDuctal carcinoma in situIntention-to-treat cohortPhase 2 open-label trialEarly-stage breast cancerInstitutional review board approvalDuctal breast carcinomaCarcinoma in situMulticenter clinical trialReview board approvalSurgical resectionBreast carcinomaEstrogen receptorPathological specimensKi67 stainingBreast cancerSurgical pathologyBoard approvalPathological analysisInitial Experience of Tomosynthesis-Guided Vacuum-Assisted Biopsies of Tomosynthesis-Detected (2D Mammography and Ultrasound Occult) Architectural Distortions.
Patel B, Covington M, Pizzitola V, Lorans R, Giurescu M, Eversman W, Lewin J. Initial Experience of Tomosynthesis-Guided Vacuum-Assisted Biopsies of Tomosynthesis-Detected (2D Mammography and Ultrasound Occult) Architectural Distortions. American Journal Of Roentgenology 2018, 210: 1395-1400. PMID: 29570367, DOI: 10.2214/ajr.17.18802.Peer-Reviewed Original ResearchConceptsVacuum-assisted biopsyPositive predictive valueDigital breast tomosynthesisInvasive cancerArchitectural distortionDuctal carcinoma in situPredictive valueGrade 1 cancersCarcinoma in situMinimally invasive methodRetrospective reviewDigital breast tomosynthesis imagesPathological examinationGrade 3Grade 2Grade 1Invasive methodBreast tomosynthesisCancerMalignancyMammographyUltrasoundGradeBiopsyCarcinomaComparison of Contrast-Enhanced Mammography and Contrast-Enhanced Breast MR Imaging
Lewin J. Comparison of Contrast-Enhanced Mammography and Contrast-Enhanced Breast MR Imaging. Magnetic Resonance Imaging Clinics Of North America 2018, 26: 259-263. PMID: 29622130, DOI: 10.1016/j.mric.2017.12.005.Peer-Reviewed Original ResearchConceptsContrast-enhanced mammographyMR imagingContrast-enhanced breast MR imagingUS Food and Drug AdministrationBreast MR imagingFood and Drug AdministrationRoutine clinical useDigital mammography unitContrast-enhanced modalityIodinated contrastChest wallPatient acceptanceClinical useDrug AdministrationDual-energyMammography unitExamination timeCancer detectionDual-energy imagingBreast cancer detectionMammographyAxillaPatientsBreast
2017
Contrast Enhanced Spectral Mammography: A Review
Patel B, Lobbes M, Lewin J. Contrast Enhanced Spectral Mammography: A Review. Seminars In Ultrasound CT And MRI 2017, 39: 70-79. PMID: 29317041, DOI: 10.1053/j.sult.2017.08.005.Peer-Reviewed Original ResearchConceptsContrast-enhanced spectral mammographyMagnetic resonance imagingTreatment responseDiagnostic accuracy of contrast-enhanced spectral mammographyAccuracy of contrast-enhanced spectral mammographySpectral mammographyDiagnostic accuracyResponse of neoadjuvant chemotherapyContrast-enhanced breast magnetic resonance imagingBreast magnetic resonance imagingNeoadjuvant chemotherapyDisease extentReview of indicationsClinical useResonance imagingDigital mammographyCancer detectionMammographyBreast cancer detectionLiterature review of indicatorsLevel of sensitivityLiterature reviewChemotherapyTumorPatients
Clinical Trials
Current Trials
Prospective, Multicenter Confirmatory Clinical Evaluation of Novilase® Interstitial Laser Therapy for the Focal Destruction of Malignant Breast Tumors ≤15 mm (BR-003)
IRB ID2000032829RolePrincipal InvestigatorPrimary Completion Date12/31/2024Recruiting ParticipantsGenderFemaleAge18+ years
Academic Achievements & Community Involvement
Clinical Care
Overview
John Lewin, MD, is a specialist in breast cancer radiotherapy. He provides comprehensive care through breast imaging, including mammography, which helps in the early detection and management of breast cancer.
As an associate professor of radiology and biomedical imaging at Yale School of Medicine, Dr. Lewin is involved in research that aims to improve breast cancer screening and diagnosis. His notable research includes pioneering the first clinical trial of digital mammography and demonstrating dual-energy contrast-enhanced mammography.
Dr. Lewin completed his medical training at Harvard Medical School and pursued residency and fellowship in breast imaging at the University of Colorado.
Clinical Specialties
Breast Cancer Radiotherapy
Fact Sheets
Breast Cancer
Learn More on Yale MedicineCancer
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Board Certifications
Diagnostic Radiology
- Certification Organization
- AB of Radiology
- Original Certification Date
- 1995
Yale Medicine News
News
News
- December 08, 2025Source: Prevention (with Dr. John Lewin)
Study: Skipping Your 1st Mammogram Increases Risk of Dying From Breast Cancer by a Shocking Amount
- May 05, 2025
Older Women May Benefit From Regular Mammograms
- September 06, 2024Source: Wall Street Journal
Why a Mammogram Isn’t Always Enough to Rule Out Cancer
- June 11, 2024Source: Everyday Health
3D vs. 2D Mammograms: What You Need to Know
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