Publications from the Division of Bioimaging Sciences

2025

Cranberry: Combined Rigid and Nonrigid Event-by-Event Motion Correction at Yale
Zhang J, Fontaine K, Volpi T, Zeng T, Du Y, Sun C, Lu Y, Toyonaga T, Onofrey J, Carson R. Cranberry: Combined Rigid and Nonrigid Event-by-Event Motion Correction at Yale. 2021 IEEE Nuclear Science Symposium And Medical Imaging Conference (NSS/MIC) 2025, 1-1. DOI: 10.1109/nss/mic/rtsd57106.2025.11286359.
Peer-Reviewed Original Research
Concepts
Impact of Depth-of-Interaction and Spatially-Variant Point-Spread-Function Model on the Performance of Ultra-High Resolution Brain PET
Zeng T, Najmaoui Y, Zhang J, Fontaine K, Hu Y, Chemli Y, Gallezot J, Sun C, Lu Y, Fakhri G, Carson R, Marin T. Impact of Depth-of-Interaction and Spatially-Variant Point-Spread-Function Model on the Performance of Ultra-High Resolution Brain PET. 2021 IEEE Nuclear Science Symposium And Medical Imaging Conference (NSS/MIC) 2025, 1-2. DOI: 10.1109/nss/mic/rtsd57106.2025.11287015.
Peer-Reviewed Original Research
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Multi-Isotope Pre-Clinical Imaging Studies with DE-SPECT: A Hyperspectral Spect System for Region-Selective 3-D Gamma-Ray Spectrometry of Cardiovascular Disease
Jin Y, Zannoni E, Thorn S, Jang S, Nazari M, Burns R, Sankar P, Zhang F, Streicher M, He Z, Metzler S, Liu C, Sinusas A, Meng L. Multi-Isotope Pre-Clinical Imaging Studies with DE-SPECT: A Hyperspectral Spect System for Region-Selective 3-D Gamma-Ray Spectrometry of Cardiovascular Disease. 2021 IEEE Nuclear Science Symposium And Medical Imaging Conference (NSS/MIC) 2025, 1-1. DOI: 10.1109/nss/mic/rtsd57106.2025.11287864.
Peer-Reviewed Original Research
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Morphological and functional alterations in type 2 diabetes pancreata assessed with MRI-based metrics and [18F]FP-(+)-DTBZ PET
Nejati S, Sadabad F, Ren R, Huang Y, Bini J. Morphological and functional alterations in type 2 diabetes pancreata assessed with MRI-based metrics and [18F]FP-(+)-DTBZ PET. Frontiers In Endocrinology 2025, 16: 1724340. DOI: 10.3389/fendo.2025.1724340.
Peer-Reviewed Original Research
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Physics-Informed List-Mode Deep Image Prior Reconstruction with Motion Correction in 3D Brain PET
Chemli Y, Najmaoui Y, Normandin M, Fakhri G, Marin T, Ouyang J. Physics-Informed List-Mode Deep Image Prior Reconstruction with Motion Correction in 3D Brain PET. 2021 IEEE Nuclear Science Symposium And Medical Imaging Conference (NSS/MIC) 2025, 1-2. DOI: 10.1109/nss/mic/rtsd57106.2025.11287851.
Peer-Reviewed Original Research
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Performance Evaluation of FastIC+ for sub-100 ps TOF-PET Module Development
Mazzanti D, Gomez S, Mauricio J, Alozy J, Auffray E, Bandi F, Campbell M, Cardona C, Dolenec R, Fakhri G, Fernandez-Tenllado J, Gola A, Guberman D, Lowis C, Majewski S, Manera R, Mariscal-Castilla A, Penna M, Pestotnik R, Paterno A, Portero S, Sanuy A, Silva J, Terragni G, Ballabriga R, Gascon D. Performance Evaluation of FastIC+ for sub-100 ps TOF-PET Module Development. 2021 IEEE Nuclear Science Symposium And Medical Imaging Conference (NSS/MIC) 2025, 1-2. DOI: 10.1109/nss/mic/rtsd57106.2025.11287230.
Peer-Reviewed Original Research
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Impact of TOF Resolution on Required Angular Coverage in PET: a Monte Carlo Study
Razdevsek G, Dolenec R, Orehar M, Fakhri G, Majewski S, Pestotnik R. Impact of TOF Resolution on Required Angular Coverage in PET: a Monte Carlo Study. 2021 IEEE Nuclear Science Symposium And Medical Imaging Conference (NSS/MIC) 2025, 1-1. DOI: 10.1109/nss/mic/rtsd57106.2025.11287018.
Peer-Reviewed Original Research
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Characterization of [ 18 F]PF-NB1 Enantiomers for Imaging NMDA GluN2B Receptors in Nonhuman Primates and Comparison with Analogous 18 F‑labeled Radiotracers
Alluri S, Zheng M, Holden D, Ahmed H, Felchner Z, Kapinos M, Carson R, Ametamey S, Huang Y. Characterization of [ 18 F]PF-NB1 Enantiomers for Imaging NMDA GluN2B Receptors in Nonhuman Primates and Comparison with Analogous 18 F‑labeled Radiotracers. ACS Chemical Neuroscience 2025 PMID: 41392471, DOI: 10.1021/acschemneuro.5c00840.
Peer-Reviewed Original Research
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Imaging Metabotropic Glutamate Receptor 5 and Excitatory Neural Activity in Autism.
Naples A, Yang Y, Gravel P, Toyonaga T, Sadabad F, Koohsari S, Pittman B, Gallezot J, Pisani L, Finn C, Cramer-Benjamin S, Herman N, Rosenthal L, Franke C, Walicki B, Rodden I, Hillmer A, Esterlis I, Ropchan J, Nabulsi N, Huang Y, Wolf J, Carson R, McPartland J, Matuskey D. Imaging Metabotropic Glutamate Receptor 5 and Excitatory Neural Activity in Autism. American Journal Of Psychiatry 2025, appiajp20241084. PMID: 41366835, DOI: 10.1176/appi.ajp.20241084.
Peer-Reviewed Original Research
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Dynamic brain mechanisms supporting salient memories under cortisol
Huang Y, O’Connor D, Harris B, Sinha R, Constable R, Goldfarb E. Dynamic brain mechanisms supporting salient memories under cortisol. Science Advances 2025, 11: eadz4143. PMID: 41370392, PMCID: PMC12693973, DOI: 10.1126/sciadv.adz4143.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Validation of Dynamic Deuterium Metabolic Imaging (DMI) for the Measurement of Cerebral Metabolic Rates of Glucose in Rat
Mathy C, Thomas M, Mason G, de Graaf R, De Feyter H. Validation of Dynamic Deuterium Metabolic Imaging (DMI) for the Measurement of Cerebral Metabolic Rates of Glucose in Rat. NMR In Biomedicine 2025, 39: e70194. PMID: 41371621, PMCID: PMC12695439, DOI: 10.1002/nbm.70194.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Three-Dimensional MRI Reconstruction with 3D Gaussian Representations: Tackling the Undersampling Problem
Peng T, Zha R, Li Z, Liu X, Zou Q. Three-Dimensional MRI Reconstruction with 3D Gaussian Representations: Tackling the Undersampling Problem. IEEE Transactions On Medical Imaging 2025, PP: 1-1. PMID: 41364570, DOI: 10.1109/tmi.2025.3642134.
Peer-Reviewed Original Research
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O119 / #388 EVALUATION OF CARDIO-RESPIRATORY-GATING FOR PROTON CARDIAC ABLATION: A LARGE-ANIMAL STUDY.
Depauw N, Bijari F, Garonna A, Kang J, Chemli Y, Deng H, Dhaynaut M, Kim H, Macdonald-Soccorso M, Moon S, Normandin M, Woodcock R, Yaghoubian M, Fakhri G, Levine R, Lehmann H, Chen Y, Jee K. O119 / #388 EVALUATION OF CARDIO-RESPIRATORY-GATING FOR PROTON CARDIAC ABLATION: A LARGE-ANIMAL STUDY. International Journal Of Particle Therapy 2025, 17: 100875. DOI: 10.1016/j.ijpt.2025.100875.
Peer-Reviewed Original Research
Neural Signatures of Bipolar Disorder and Psychotropic Medication Effects: A Multimodal PET–MRI Study
Asch R, Fan S, Cool R, Boster S, DellaGioia N, Naganawa M, Nabulsi N, Lacadie C, Pietrzak R, Esterlis I. Neural Signatures of Bipolar Disorder and Psychotropic Medication Effects: A Multimodal PET–MRI Study. Biological Psychiatry 2025 PMID: 41325959, DOI: 10.1016/j.biopsych.2025.11.018.
Peer-Reviewed Original Research
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Development and Initial Evaluation of 3D-Printed High Resolution Brain Phantom for PET
Lo C, Shanina E, Gravel P, Hu Y, Lucero S, Martins S, Mulnix T, Fontaine K, Nejati S, Sun X, Li H, Qi J, Cherry S, Carson R, Toyonaga T. Development and Initial Evaluation of 3D-Printed High Resolution Brain Phantom for PET. IEEE Transactions On Radiation And Plasma Medical Sciences 2025, PP: 1-1. PMID: 41446501, PMCID: PMC12724537, DOI: 10.1109/trpms.2025.3638588.
Peer-Reviewed Original Research
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Corrigendum to “Applying dual energy computed tomography to postmortem coronary computed tomographic angiography” [J Cardiovasc Comput Tomogr (in press)]
Solomon N, Hoerner M, Vermillion B, Jang S, Sanchez H, Gosangi B, Staib L, Thorn S, Liu C, Sinusas A. Corrigendum to “Applying dual energy computed tomography to postmortem coronary computed tomographic angiography” [J Cardiovasc Comput Tomogr (in press)]. Journal Of Cardiovascular Computed Tomography 2025 PMID: 41309332, DOI: 10.1016/j.jcct.2025.11.003.
Peer-Reviewed Original Research
Experimental Evaluation of DE-SPECT: A Hyperspectral SPECT System for Region-Selective 3-D Gamma-Ray Spectroscopy
Jin Y, Zannoni E, Sankar P, Zhang F, Streicher M, Yang H, He Z, Metzler S, Liu C, Sinusas A, Meng L. Experimental Evaluation of DE-SPECT: A Hyperspectral SPECT System for Region-Selective 3-D Gamma-Ray Spectroscopy. IEEE Transactions On Radiation And Plasma Medical Sciences 2025, PP: 1-1. DOI: 10.1109/trpms.2025.3630554.
Peer-Reviewed Original Research
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Nuclear Medicine AI in Action: The Bethesda Report (AI Summit 2024).
Rahmim A, Bradshaw T, Davidzon G, Dutta J, El Fakhri G, Ghesani M, Karakatsanis N, Li Q, Liu C, Roncali E, Saboury B, Yusufaly T, Jha A. Nuclear Medicine AI in Action: The Bethesda Report (AI Summit 2024). Journal Of Nuclear Medicine 2025, jnumed.125.269540. PMID: 41290370, DOI: 10.2967/jnumed.125.269540.
Peer-Reviewed Original Research
Imaging Neuroimmune Dysfunction: From TSPO to Emerging PET Targets
Bonomi R, Raval N, Hillmer A, Cosgrove K. Imaging Neuroimmune Dysfunction: From TSPO to Emerging PET Targets. Biological Psychiatry 2025 PMID: 41297785, DOI: 10.1016/j.biopsych.2025.11.010.
Peer-Reviewed Original Research
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Transdiagnostic similarities and distinctions in brain networks associated with autistic social impairments: a prospective cohort study
Bruno J, Plank J, Leder S, Lake E, Finn E, Green T. Transdiagnostic similarities and distinctions in brain networks associated with autistic social impairments: a prospective cohort study. Molecular Autism 2025, 16: 56. PMID: 41257798, PMCID: PMC12628569, DOI: 10.1186/s13229-025-00686-w.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Associations of Prenatal Social Support in Adolescent Mothers With Measures of Social‐Emotional Development in Their Young Children
Holland C, Sun H, Rodriguez R, Bennett M, Cheng B, Peterson B, Scheinost D, Spann M. Associations of Prenatal Social Support in Adolescent Mothers With Measures of Social‐Emotional Development in Their Young Children. Brain And Behavior 2025, 15: e71059. PMID: 41250941, PMCID: PMC12623451, DOI: 10.1002/brb3.71059.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Multicenter PET Image Harmonization Using Style-Guided CycleGAN in Primary Central Nervous System Lymphoma : InStyleGAN
Arzur D, Marin T, Horowitz T, Kas A, El Fakhri G, Mhiri I, Rozenblum L. Multicenter PET Image Harmonization Using Style-Guided CycleGAN in Primary Central Nervous System Lymphoma : InStyleGAN. Lecture Notes In Computer Science 2025, 16164: 126-138. DOI: 10.1007/978-3-032-07904-6_12.
Peer-Reviewed Original Research
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Central Nervous System Biodistribution and Pharmacokinetics of Radiolabeled Tofersen in Rodents, Nonhuman Primates, and Humans.
Cook B, McLaren D, Sullivan J, El Fakhri G, Yokell D, Freeman M, Currier N, Oestergaard M, Dobson H, Hesterman J, Salem N, Nestorov I, Monine M, Martarello L, Evans K, Fradette S, Ferguson T, Graham D, Passamonti L. Central Nervous System Biodistribution and Pharmacokinetics of Radiolabeled Tofersen in Rodents, Nonhuman Primates, and Humans. Journal Of Nuclear Medicine 2025, jnumed.125.270731. PMID: 41233143, DOI: 10.2967/jnumed.125.270731.
Peer-Reviewed Original Research
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BrainEffeX: A web app for exploring fMRI effect sizes
Shearer H, Rosenblatt M, Ye J, Jiang R, Tejavibulya L, Foster M, Liang Q, Dadashkarimi J, Westwater M, Cahill C, Cheng I, Fischbach A, Humphries A, Rolison M, Peterson H, Adkinson B, Mehta S, Camp C, Nichols T, Curtiss J, Scheinost D, Noble S. BrainEffeX: A web app for exploring fMRI effect sizes. Aperture Neuro 2025, 5 DOI: 10.52294/001c.146251.
Peer-Reviewed Original Research
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YRT-PET-NX: Development of a Plugin for an Open-Source PET Reconstruction Platform to Support the NeuroEXPLORER
Najmaoui Y, Fontaine K, Fontaine D, Zhang J, Zeng T, Volpi T, Chemli Y, Gallezot J, Tétrault M, Carson R, Fakhri G, Marin T. YRT-PET-NX: Development of a Plugin for an Open-Source PET Reconstruction Platform to Support the NeuroEXPLORER. 2025, 00: 1-2. DOI: 10.1109/nss/mic/rtsd57106.2025.11287275.
Peer-Reviewed Original Research
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