Albert E. Kent Associate Professor of Psychiatry and Associate Professor of Cellular and Molecular Physiology; Director of Scientist Diversity and Inclusion, YSM Office of Diversity, Equity and Inclusion
TCORS 3.0
Project 1
Beyond Characterizing Flavors: Effects of Odorless Constituents (sensory additives, solvents, and synthetic nicotine) on Tobacco Product Use Behaviors from Adolescence to Adulthood
Project 1 will examine how odorless cooling additives, sweeteners, and sweet solvent/ humectants, as well as nicotine stereoisomers impact nicotine initiation, preference, reinforcement, and transitions in use from adolescence to adulthood.
Research Team
Associate Professor of Anesthesiology, Pharmacology & Cancer Biology, University Program of Environmental Health (UPEH), Duke University School of Medicine
Charles B. G. Murphy Professor of Psychiatry and Professor in the Child Study Center, of Neuroscience and of Pharmacology; Director Division of Molecular Psychiatry, Psychiatry; Deputy Chair for Basic Science Research, Dept. of Psychiatry; Director, Interdepartmental Neuroscience Program
Project 2
Addictive Threshold of Nicotine and the Impact of Sweeteners
Project 2 will determine if thresholds for nicotine reinforcement, discrimination, and subjective rewarding effects differ among adults who smoke cigarettes and if these thresholds are altered by exposure to sweeteners.
Research Team
Professor of Psychiatry; Director of VA New England Mental Illness Research, Education and Clinical Center (MIRECC)
Project 3
Examining Appeal and Addiction Potential of Novel E-cigarette Constituents
Project 3 will determine how novel nicotine forms (synthetic nicotine) and novel flavor additives (synthetic coolants) impact e-cigarette appeal and addiction potential among adults who use e-cigarettes and combustible tobacco products.
Research Team
Albert E. Kent Professor of Psychiatry; Chair, Human Investigations Committee (IRB), Human Research Protections Program; Professor, Chronic Disease Epidemiology
Project 4
Evaluating the Effects of E-cigarettes vs. Oral Nicotine Pouches and Product Constituents (menthol flavor, nicotine concentration) on Adult Cigarette Smoking and Addiction
Project 4 will model potential regulations of cooling flavors and nicotine concentrations in non-combustible tobacco products (nicotine pouches, e-cigarettes) and examine their impact on adult’s ability to switch from smoking cigarettes to using less harmful, non-combustible products.
Research Team
Associate Professor of Psychiatry; Director, Tobacco Treatment Service, Psychiatry