2005
Sex-Related Differences in Stimulated Hypothalamic-Pituitary-Adrenal Axis during Induced Gonadal Suppression
Roca C, Schmidt P, Deuster P, Danaceau M, Altemus M, Putnam K, Chrousos G, Nieman L, Rubinow D. Sex-Related Differences in Stimulated Hypothalamic-Pituitary-Adrenal Axis during Induced Gonadal Suppression. The Journal Of Clinical Endocrinology & Metabolism 2005, 90: 4224-4231. PMID: 15886244, DOI: 10.1210/jc.2004-2525.Peer-Reviewed Original ResearchConceptsSex-related differencesGonadal suppressionReproductive steroid levelsHypogonadal conditionsAdrenal axisSteroid levelsCortisol-binding globulin levelsCRH stimulation testSex differencesHPA axis measuresHPA axis responseMain outcome measuresHPA axis activityMiddle-aged menFemale normal volunteersLeuprolide injectionACTH ratioCRH stimulationOutpatient clinicStimulation testLeuprolide acetateTime of testingAdrenal responsivityAxis activityGlobulin levels
1999
Association of the serotonin transporter promoter regulatory region polymorphism and obsessive-compulsive disorder
Bengel D, Greenberg B, Corá-Locatelli G, Altemus M, Heils A, Li Q, Murphy D. Association of the serotonin transporter promoter regulatory region polymorphism and obsessive-compulsive disorder. Molecular Psychiatry 1999, 4: 463-466. PMID: 10523819, DOI: 10.1038/sj.mp.4000550.Peer-Reviewed Original ResearchMeSH KeywordsAllelesCarrier ProteinsCase-Control StudiesChi-Square DistributionFemaleGene FrequencyGenetic LinkageGenetic Predisposition to DiseaseGenotypeHumansMaleMembrane GlycoproteinsMembrane Transport ProteinsNerve Tissue ProteinsObsessive-Compulsive DisorderPolymorphism, GeneticPromoter Regions, GeneticSerotonin Plasma Membrane Transport ProteinsWhite PeopleConceptsObsessive-compulsive disorderRecent family-based studyCentral serotonergic systemTreatment of OCDNon-patient control groupSerotonergic agentsSerotonin reuptakeCaucasian patientsSerotonergic neurotransmissionSerotonergic systemControl groupFamily-based studyFunctional polymorphismsSerotonin transporterRegulatory region polymorphismKey modulatorPatientsRegion polymorphismsDisordersLong allelePolymorphismAssociationPreliminary study
1996
Intact coding region of the serotonin transporter gene in obsessive‐compulsive disorder
Altemus M, Murphy D, Greenberg B, Lesch K. Intact coding region of the serotonin transporter gene in obsessive‐compulsive disorder. American Journal Of Medical Genetics 1996, 67: 409-411. PMID: 8837711, DOI: 10.1002/(sici)1096-8628(19960726)67:4<409::aid-ajmg16>3.0.co;2-n.Peer-Reviewed Original Research