2004
Puberty, Ovarian Steroids, and Stress
YOUNG E, ALTEMUS M. Puberty, Ovarian Steroids, and Stress. Annals Of The New York Academy Of Sciences 2004, 1021: 124-133. PMID: 15251881, DOI: 10.1196/annals.1308.013.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsFemaleGlucocorticoidsHumansHypothalamo-Hypophyseal SystemOvaryPituitary-Adrenal SystemPubertySex CharacteristicsSteroidsStress, PhysiologicalConceptsStressful life eventsMajor depressionDepressed womenPostmenopausal depressed womenReproductive hormonal changesLife eventsNormal progesteronePremenopausal womenCommon etiologyOvarian hormonesOvarian steroidsHPA axisAdrenal axisNormal womenLow estradiolFirst episodeDepressed menHormonal changesBaseline cortisolEstradiolInhibitory feedbackPubertyYoung adulthoodWomenDepression
2001
Increased Vasopressin and Adrenocorticotropin Responses to Stress in the Midluteal Phase of the Menstrual Cycle
Altemus M, Roca C, Galliven E, Romanos C, Deuster P. Increased Vasopressin and Adrenocorticotropin Responses to Stress in the Midluteal Phase of the Menstrual Cycle. The Journal Of Clinical Endocrinology & Metabolism 2001, 86: 2525-2530. PMID: 11397850, DOI: 10.1210/jcem.86.6.7596.Peer-Reviewed Original ResearchMeSH KeywordsAdrenocorticotropic HormoneAdultBlood GlucoseExerciseFemaleHumansLuteal PhaseStress, PhysiologicalVasopressinsConceptsEarly follicular phaseMaximal oxygen consumptionMidluteal phaseMenstrual cycleFollicular phaseGonadal steroidsNatural menstrual cycleMin of exerciseHPA axis responsivityGonadal steroid levelsPathophysiology of anxietyAdrenocorticotropin responseHealthy womenEstrogen levelsHPA axisAdrenal axisExercise stressSteroid levelsCortisol levelsExercise intensityPlasma lactateHormonal responsesVasopressinProvide protectionACTH
1995
Suppression of hypothalmic-pituitary-adrenal axis responses to stress in lactating women
Altemus M, Deuster P, Galliven E, Carter C, Gold P. Suppression of hypothalmic-pituitary-adrenal axis responses to stress in lactating women. The Journal Of Clinical Endocrinology & Metabolism 1995, 80: 2954-2959. PMID: 7559880, DOI: 10.1210/jcem.80.10.7559880.Peer-Reviewed Original ResearchConceptsNeurohormonal systemsTreadmill exerciseBasal norepinephrine levelsIntensity-dependent activationAdrenal axis responseMin of exerciseMaximal oxygen uptakeSympathomedullary systemNorepinephrine levelsBreast feedingPlasma ACTHAdrenal axisNonlactating womenWeeks postpartumAxis responseGlucose responseWomenPhysical conditioningOxygen uptakeExerciseSubjectsPhysiological responsesResponseACTHPostpartumStress and antidepressants differentially regulate neurotrophin 3 mRNA expression in the locus coeruleus.
Smith M, Makino S, Altemus M, Michelson D, Hong S, Kvetnansky R, Post R. Stress and antidepressants differentially regulate neurotrophin 3 mRNA expression in the locus coeruleus. Proceedings Of The National Academy Of Sciences Of The United States Of America 1995, 92: 8788-8792. PMID: 7568018, PMCID: PMC41052, DOI: 10.1073/pnas.92.19.8788.Peer-Reviewed Original ResearchConceptsNT-3 mRNA levelsLocus coeruleusNT-3MRNA levelsNeurotrophin-3 (NT-3) mRNA expressionSerotonin-specific reuptake inhibitorsNT-3 levelsNT-3 expressionSurvival of neuronsEffects of stressAntidepressant treatmentElectroconvulsive seizuresChronic treatmentLC neuronsNoradrenergic neuronsReuptake inhibitorsNeurotrophin expressionNeurotrophic factorNeurotrophin-3Norepinephrine uptakeImmobilization stressMood disordersLC functionAntidepressantsClinical depression