1999
Open trial of flutamide for treatment of obsessive-compulsive disorder.
Altemus M, Greenberg B, Keuler D, Jacobson K, Murphy D. Open trial of flutamide for treatment of obsessive-compulsive disorder. The Journal Of Clinical Psychiatry 1999, 60: 442-5. PMID: 10453797, DOI: 10.4088/jcp.v60n0704.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderAndrogen receptorEstrogen receptorClassical intracellular androgen receptorsOCD symptomsPrimary outcome measureFuture treatment trialsIntracellular androgen receptorHamilton Rating ScaleGonadal steroid hormonesAndrogen receptor antagonistYale-Brown Obsessive Compulsive ScaleEffect of treatmentBeck Anxiety InventoryLack of responseObsessive Compulsive ScaleOpen trialTreatment trialsReceptor antagonistGonadal steroidsOutcome measuresCompetitive antagonistEstrogen activityFlutamideSteroid hormones
1996
Behavioral effects of naloxone infusion in obsessive-compulsive disorder
Keuler D, Altemus M, Michelson D, Greenberg B, Murphy D. Behavioral effects of naloxone infusion in obsessive-compulsive disorder. Biological Psychiatry 1996, 40: 154-156. PMID: 8793049, DOI: 10.1016/0006-3223(95)00632-x.Peer-Reviewed Original Research
1991
Symptoms of eating disorders in patients with obsessive-compulsive disorder
Pigott T, Altemus M, Rubenstein C, Hill J, Bihari K, L'Heureux F, Bernstein S, Murphy D. Symptoms of eating disorders in patients with obsessive-compulsive disorder. American Journal Of Psychiatry 1991, 148: 1552-1557. PMID: 1928472, DOI: 10.1176/ajp.148.11.1552.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderEating Disorder InventoryHealthy comparison subjectsDisorder InventoryComparison subjectsSelf-rating scaleBody dissatisfactionEating AttitudesInteroceptive awarenessDisorder displayInterpersonal distrustMaturity fearsBehavioral dimensionsBulimia nervosaAnorexia nervosaFemale normal subjectsReliable measureMore symptomsDisorders ClinicFemale inpatientsInventoryNervosaPotential overlapDisordersAttitudes