2005
Sex-Related Differences in Stimulated Hypothalamic-Pituitary-Adrenal Axis during Induced Gonadal Suppression
Roca C, Schmidt P, Deuster P, Danaceau M, Altemus M, Putnam K, Chrousos G, Nieman L, Rubinow D. Sex-Related Differences in Stimulated Hypothalamic-Pituitary-Adrenal Axis during Induced Gonadal Suppression. The Journal Of Clinical Endocrinology & Metabolism 2005, 90: 4224-4231. PMID: 15886244, DOI: 10.1210/jc.2004-2525.Peer-Reviewed Original ResearchConceptsSex-related differencesGonadal suppressionReproductive steroid levelsHypogonadal conditionsAdrenal axisSteroid levelsCortisol-binding globulin levelsCRH stimulation testSex differencesHPA axis measuresHPA axis responseMain outcome measuresHPA axis activityMiddle-aged menFemale normal volunteersLeuprolide injectionACTH ratioCRH stimulationOutpatient clinicStimulation testLeuprolide acetateTime of testingAdrenal responsivityAxis activityGlobulin levels
2001
Increased Vasopressin and Adrenocorticotropin Responses to Stress in the Midluteal Phase of the Menstrual Cycle
Altemus M, Roca C, Galliven E, Romanos C, Deuster P. Increased Vasopressin and Adrenocorticotropin Responses to Stress in the Midluteal Phase of the Menstrual Cycle. The Journal Of Clinical Endocrinology & Metabolism 2001, 86: 2525-2530. PMID: 11397850, DOI: 10.1210/jcem.86.6.7596.Peer-Reviewed Original ResearchConceptsEarly follicular phaseMaximal oxygen consumptionMidluteal phaseMenstrual cycleFollicular phaseGonadal steroidsNatural menstrual cycleMin of exerciseHPA axis responsivityGonadal steroid levelsPathophysiology of anxietyAdrenocorticotropin responseHealthy womenEstrogen levelsHPA axisAdrenal axisExercise stressSteroid levelsCortisol levelsExercise intensityPlasma lactateHormonal responsesVasopressinProvide protectionACTH