1995
Symptom overlap between OCD and bulimia nervosa
Rubenstein C, Altemus M, Pigott T, Hess A, Murphy D. Symptom overlap between OCD and bulimia nervosa. Journal Of Anxiety Disorders 1995, 9: 1-9. DOI: 10.1016/0887-6185(95)91551-r.Peer-Reviewed Original ResearchObsessive-compulsive disorderBulimic patientsOCD patientsNormal volunteersBulimia nervosaFemale bulimia nervosa patientsSCL-90Hamilton Depression Rating ScoreDepression rating scoresEffective nonpharmacological treatmentBulimia nervosa patientsInpatient treatment programFemale OCD patientsMeasures of depressionNonpharmacological treatmentsNormal womenNervosa patientsNormal controlsDepression subscalePsychiatric disordersPatientsSymptom overlapTreatment programSignificant decreaseBulimia subscale
1994
Changes in Cerebrospinal Fluid Neurochemistry During Treatment of Obsessive-compulsive Disorder With Clomipramine
Altemus M, Swedo S, Leonard H, Richter D, Rubinow D, Potter W, Rapoport J. Changes in Cerebrospinal Fluid Neurochemistry During Treatment of Obsessive-compulsive Disorder With Clomipramine. JAMA Psychiatry 1994, 51: 794-803. PMID: 7524463, DOI: 10.1001/archpsyc.1994.03950100042004.Peer-Reviewed Original ResearchConceptsCorticotropin-releasing hormoneLong-term treatmentObsessive-compulsive disorderCSF levelsHomovanillic acidCSF monoamine metabolite levelsCentral administrationCerebrospinal fluid levelsSignificant decreaseCSF homovanillic acidMonoamine metabolite levelsCerebrospinal fluid neurochemistryCSF oxytocin levelsOpposite behavioral effectsPharmacologic treatmentSomatostatin levelsMonoamine metabolitesPathophysiologic processesFluid levelsBehavioral effectsOxytocin levelsClomipramine hydrochlorideMetabolite levelsDisordersVasopressin