2005
Synchronized Maternal-Infant Elevations of Primate CSF CRF Concentrations in Response to Variable Foraging Demand
Coplan J, Altemus M, Mathew S, Smith E, Sharf B, Coplan P, Kral J, Gorman J, Owens M, Nemeroff C, Rosenblum L. Synchronized Maternal-Infant Elevations of Primate CSF CRF Concentrations in Response to Variable Foraging Demand. CNS Spectrums 2005, 10: 530-536. PMID: 16155510, DOI: 10.1017/s109285290001018x.Peer-Reviewed Original ResearchConceptsCentral corticotropin-releasing factorCSF CRF concentrationsCRF concentrationsCentral CRF systemCorticotropin-releasing factorSignificant mean increaseCerebrospinal fluid samplesEarly life stressorsVFD conditionsInfant sex differencesEnvironment-gene interactionsCRF levelsCRF expressionPsychiatric disordersCRF responseCRF systemInfant's lifeMean increaseDays postpartumInfantsStudy periodFluid samplesMothersMaternal responsivitySex differences
2003
Enhanced Cellular Immune Response in Women With PTSD Related to Childhood Abuse
Altemus M, Cloitre M, Dhabhar F. Enhanced Cellular Immune Response in Women With PTSD Related to Childhood Abuse. American Journal Of Psychiatry 2003, 160: 1705-1707. PMID: 12944352, DOI: 10.1176/appi.ajp.160.9.1705.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderDelayed-type hypersensitivity (DTH) skin test responsesCircadian salivary cortisol levelsHypersensitivity skin test responsesDelayed-type hypersensitivitySkin test responsesCellular immune responsesHPA axis activityCell-mediated inflammatory reactionsHealthy comparison subjectsSalivary cortisol levelsAdrenal axisSympathoadrenomedullary systemAxis activityInflammatory reactionImmune responseImmune functionPsychiatric disordersComparison subjectsCortisol levelsPlasma cortisolHistory of abuseSingle time point measurementStress disorderTime point measurements
1995
Symptom overlap between OCD and bulimia nervosa
Rubenstein C, Altemus M, Pigott T, Hess A, Murphy D. Symptom overlap between OCD and bulimia nervosa. Journal Of Anxiety Disorders 1995, 9: 1-9. DOI: 10.1016/0887-6185(95)91551-r.Peer-Reviewed Original ResearchObsessive-compulsive disorderBulimic patientsOCD patientsNormal volunteersBulimia nervosaFemale bulimia nervosa patientsSCL-90Hamilton Depression Rating ScoreDepression rating scoresEffective nonpharmacological treatmentBulimia nervosa patientsInpatient treatment programFemale OCD patientsMeasures of depressionNonpharmacological treatmentsNormal womenNervosa patientsNormal controlsDepression subscalePsychiatric disordersPatientsSymptom overlapTreatment programSignificant decreaseBulimia subscale