2006
The Biological Underpinnings of Depression
Korszun A, Altemus M, Young E. The Biological Underpinnings of Depression. 2006, 41-61. DOI: 10.1017/cbo9780511841262.005.Peer-Reviewed Original ResearchAdrenocorticotropic hormoneDepressive disorderHypothalamic pituitary adrenal axisAnterior pituitary corticotropesPituitary-adrenal axisDevelopment of depressionCases of depressionStress-related conditionsGlucocorticoid feedbackPituitary siteAdrenal axisHPA axisCortisol secretionExaggerated responseAdrenal glucocorticoidsPituitary corticotropesHormonal systemsDepressionGenetic vulnerabilityComplex dynamic equilibriumBiological underpinningsCentral effectorIntroduction StressExtrinsic stressorsLife events
1993
Cerebrospinal fluid monoamine metabolites in fluoxetine-treated patients with major depression and in healthy volunteers
De Bellis M, Geracioti T, Altemus M, Kling M. Cerebrospinal fluid monoamine metabolites in fluoxetine-treated patients with major depression and in healthy volunteers. Biological Psychiatry 1993, 33: 636-641. PMID: 7687151, DOI: 10.1016/0006-3223(93)90103-k.Peer-Reviewed Original ResearchConceptsMedication-free patientsHealthy volunteersFluoxetine treatmentHomovanillic acidMean Hamilton Depression Rating Scale scoreHamilton Depression Rating Scale scoresDepression Rating Scale scoresPmol/CSF monoamine metabolite levelsFluoxetine-treated patientsCerebrospinal fluid levelsMajor depressive disorderMonoamine metabolite levelsRating Scale scoresCerebrospinal fluid monoamineHVA/5-HIAA ratioCSF HVA/5-HIAA ratioDepressive disorderMajor depressionScale scoreFluid levelsPatientsDSM-IIIMetabolite levelsVolunteers