2006
The Biological Underpinnings of Depression
Korszun A, Altemus M, Young E. The Biological Underpinnings of Depression. 2006, 41-61. DOI: 10.1017/cbo9780511841262.005.Peer-Reviewed Original ResearchAdrenocorticotropic hormoneDepressive disorderHypothalamic pituitary adrenal axisAnterior pituitary corticotropesPituitary-adrenal axisDevelopment of depressionCases of depressionStress-related conditionsGlucocorticoid feedbackPituitary siteAdrenal axisHPA axisCortisol secretionExaggerated responseAdrenal glucocorticoidsPituitary corticotropesHormonal systemsDepressionGenetic vulnerabilityComplex dynamic equilibriumBiological underpinningsCentral effectorIntroduction StressExtrinsic stressorsLife events
2004
Puberty, Ovarian Steroids, and Stress
YOUNG E, ALTEMUS M. Puberty, Ovarian Steroids, and Stress. Annals Of The New York Academy Of Sciences 2004, 1021: 124-133. PMID: 15251881, DOI: 10.1196/annals.1308.013.Peer-Reviewed Original ResearchConceptsStressful life eventsMajor depressionDepressed womenPostmenopausal depressed womenReproductive hormonal changesLife eventsNormal progesteronePremenopausal womenCommon etiologyOvarian hormonesOvarian steroidsHPA axisAdrenal axisNormal womenLow estradiolFirst episodeDepressed menHormonal changesBaseline cortisolEstradiolInhibitory feedbackPubertyYoung adulthoodWomenDepression
2000
CSF oxytocin and vasopressin levels after recovery from bulimia nervosa and anorexia nervosa, bulimic subtype
Frank G, Kaye W, Altemus M, Greeno C. CSF oxytocin and vasopressin levels after recovery from bulimia nervosa and anorexia nervosa, bulimic subtype. Biological Psychiatry 2000, 48: 315-318. PMID: 10960163, DOI: 10.1016/s0006-3223(00)00243-2.Peer-Reviewed Original ResearchConceptsCerebrospinal fluid vasopressinMajor depressionBulimia nervosaAnorexia nervosaLifetime historyBirth control pill useHealthy control womenBulimic subtypeControl womenVasopressin levelsPill useRecovered subjectsIll stateElevated levelsVasopressinNervosaCSF oxytocinOxytocinNeuropeptide vasopressinCerebrospinal fluid oxytocinWomenDisordersDepression
1995
Working memory as assessed by subject-ordered tasks in patients with obsessive-compulsive disorderxs
Martin A, Wiggs C, Altemus M, Rubenstein C, Murphy D. Working memory as assessed by subject-ordered tasks in patients with obsessive-compulsive disorderxs. Journal Of Clinical And Experimental Neuropsychology 1995, 17: 786-792. PMID: 8557818, DOI: 10.1080/01688639508405167.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderOCD patientsNormal recognition memorySelf-paced taskPrefrontal lobe dysfunctionFocal brain lesionsMemory spanMemory taskRecognition memorySlowed performanceOCD symptomsPrefrontal cortexFunctional brainTaskMemoryBrain lesionsResponse timeStudy of NormalAnxietyRatingsCortexDepressionStudy of patientsDisordersPerformance