Kim Germaine Emiel Smolderen, PhD, MSc
ProfessorCards
About
Research
Publications
2025
Inpatient Outcomes for Patients With Peripheral Artery Disease Hospitalized for Acute Myocardial Infarction.
Gusdorf J, Faridi K, Wang T, Mena-Hurtado C, Smolderen K, Rymer J, Curtis J, Li S, Secemsky E. Inpatient Outcomes for Patients With Peripheral Artery Disease Hospitalized for Acute Myocardial Infarction. Journal Of The American Heart Association 2025, 14: e040526. PMID: 40497502, DOI: 10.1161/jaha.124.040526.Peer-Reviewed Original ResearchConceptsAcute myocardial infarction typesPeripheral arterial diseaseAcute myocardial infarctionIn-hospital mortalityPeripheral artery disease hospitalizationsIn-hospital outcomesAcute myocardial infarction hospitalizationsCardiac arrestHigh-risk populationAssociated with increased ratesLong-term riskRevascularized patientsInpatient outcomesMultivariable adjustmentHeart failureArtery diseasePrimary outcomeAdverse cardiovascular outcomesUS sitesHeightened riskAge groupsSecondary end pointsSubgroup analysisDialysis initiationCoronary artery diseaseImpact of Sudden Cardiac Arrest and Implantable Cardiac Defibrillator Shocks on Mental Health Review and Management Guidance
Torbey E, Mena-Hurtado C, Jackson J, Samaan Z, Sears S, Pedersen S, Lala A, Thachil R, Steiner J, Ilonze O, Jones D, Watson K, Price A, Knoepke C, Cheung J, Smolderen K, Group A. Impact of Sudden Cardiac Arrest and Implantable Cardiac Defibrillator Shocks on Mental Health Review and Management Guidance. JACC Advances 2025, 4: 101797. PMID: 40373523, PMCID: PMC12144438, DOI: 10.1016/j.jacadv.2025.101797.Peer-Reviewed Original ResearchSurvivors of sudden cardiac arrestSudden cardiac arrestMental healthHealth care seekingMental health reviewPost-traumatic stress symptomsUntreated mental healthCardiac arrestCare-seekingCare planningImprove wellnessHealth reviewStress symptomsPost-SCAUsual lifeHealthFollow-upDefibrillation shocksManagement guidanceExperience shockSymptomsICDImplantable cardiac defibrillator shockDefibrillationAdherenceDiabetes Status and Long-Term Mortality and Major Amputation Outcomes Following Revascularization in Chronic Limb Threatening Ischemia
Callegari S, Romain G, Aggarwal A, Cleman J, Smolderen K, Mena-Hurtado C. Diabetes Status and Long-Term Mortality and Major Amputation Outcomes Following Revascularization in Chronic Limb Threatening Ischemia. Journal Of Vascular Surgery 2025 PMID: 40348290, DOI: 10.1016/j.jvs.2025.04.065.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaLower-extremity bypassSub-hazard ratiosPeripheral vascular interventionsDM statusRisk of deathLimb-threatening ischemiaTeam-based careShared decision-makingCumulative incidenceDiabetes mellitusMedicare claims dataCumulative incidence of mortalityAll-cause mortalityType of revascularizationAmputation outcomesCare offerFine-Gray modelClaims dataCumulative incidence of deathLong-term mortalityMortality riskCox regression modelsHazard ratioDiabetes statusVARIABILITY IN GUIDELINE-DIRECTED MEDICAL THERAPY AMONG SITES AND OPERATORS AND PATIENT FACTORS ASSOCIATED WITH ITS USAGE FOLLOWING CAROTID ARTERY STENTING
Jallow M, Romain G, AL Mouslmani M, Rahman M, Tapia C, Kansal D, Jamil Y, Pajarillo C, Mena G, Mubarak E, Vashist A, Filho J, Smolderen K, Hurtado C. VARIABILITY IN GUIDELINE-DIRECTED MEDICAL THERAPY AMONG SITES AND OPERATORS AND PATIENT FACTORS ASSOCIATED WITH ITS USAGE FOLLOWING CAROTID ARTERY STENTING. Journal Of The American College Of Cardiology 2025, 85: 2399. DOI: 10.1016/s0735-1097(25)02883-9.Peer-Reviewed Original ResearchCHRONIC PAIN DISORDERS, OPIOID USE AND 1-YEAR MORTALITY OUTCOMES IN PATIENTS UNDERGOING PERIPHERAL VASCULAR INTERVENTION FOR CHRONIC LIMB THREATENING ISCHEMIA
Rahman M, Romain G, Tapia C, AL Mouslmani M, Jallow M, Mena G, Mubarak E, Filho J, Vashist A, Hurtado C, Smolderen K. CHRONIC PAIN DISORDERS, OPIOID USE AND 1-YEAR MORTALITY OUTCOMES IN PATIENTS UNDERGOING PERIPHERAL VASCULAR INTERVENTION FOR CHRONIC LIMB THREATENING ISCHEMIA. Journal Of The American College Of Cardiology 2025, 85: 2405. DOI: 10.1016/s0735-1097(25)02889-x.Peer-Reviewed Original ResearchBLOOD PRESSURE CONTROL AND RISK OF CARDIOVASCULAR AND LIMB EVENTS IN PERIPHERAL ARTERY DISEASE PATIENTS
Girotra S, Gupta A, Chan P, Li Q, Lund B, vaughansarrazin M, Nguyen C, Kumbhani D, Gobbel G, Arya S, Bavry A, Smolderen K, Hoffman R, Vongpatanasin W, De Lemos J, Beckman J. BLOOD PRESSURE CONTROL AND RISK OF CARDIOVASCULAR AND LIMB EVENTS IN PERIPHERAL ARTERY DISEASE PATIENTS. Journal Of The American College Of Cardiology 2025, 85: 435. DOI: 10.1016/s0735-1097(25)00919-2.Peer-Reviewed Original ResearchOutcomes of chronic limb-threatening ischemia revascularization in patients with chronic kidney disease in the BEST-CLI trial Presented at the Southern Association for Vascular Surgery Forty-ninth Annual Meeting, Frenchman's Reef in St. Thomas, USVI, January 22-25, 2025.
Malas M, Hamouda M, Farber A, Menard M, Conte M, Rosenfield K, Strong M, Doros G, Powell R, Mena-Hurtado C, Gasper W, Schermerhorn M, Allievi S, Smolderen K, Dake M, Rymer J, Tuttle K. Outcomes of chronic limb-threatening ischemia revascularization in patients with chronic kidney disease in the BEST-CLI trial Presented at the Southern Association for Vascular Surgery Forty-ninth Annual Meeting, Frenchman's Reef in St. Thomas, USVI, January 22-25, 2025. European Journal Of Vascular And Endovascular Surgery 2025, 69: e262-e263. DOI: 10.1016/j.ejvs.2025.02.053.Peer-Reviewed Original ResearchLong‐Term Outcomes of Peripheral Artery Disease in Veterans: Analysis of the Peripheral Artery Disease Long‐Term Survival Study (PEARLS)
Girotra S, Li Q, Vaughan‐Sarrazin M, Lund B, Al‐Garadi M, Beckman J, Nathani R, Hoffman R, Chan P, Banerjee S, Tsai S, Kumbhani D, Minniefield‐Young N, Smolderen K, Arya S, Nguyen C, Matheny M, Gobbel G. Long‐Term Outcomes of Peripheral Artery Disease in Veterans: Analysis of the Peripheral Artery Disease Long‐Term Survival Study (PEARLS). Journal Of The American Heart Association 2025, 14: e038403. PMID: 40118806, PMCID: PMC12132885, DOI: 10.1161/jaha.124.038403.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationPeripheral arterial diseaseHealth AdministrationIntegrated health systemOutcomes of peripheral artery diseaseDiagnosis of peripheral arterial diseaseToe-brachial index valuesPrevalence of hypertensionLimb eventsChronic obstructive pulmonary diseaseAnkle-brachial indexImprove careHealth systemObstructive pulmonary diseaseCardiovascular eventsHigh-risk groupNational registryArtery diseaseVeteransIncidence of cardiovascular eventsRegistryIncidence of deathPulmonary diseasePatient yearsStudy end pointEffect of Diabetes on Clinical Outcomes in Patients with Peripheral Arterial Disease undergoing Lower Extremity Revascularization: A Systematic Review and Meta-Analysis
Edjimbi J, Shah N, Kwaah P, Grimshaw A, Regan C, Nagpal S, Attaran R, Chaar C, Romain G, Smolderen K, Mena-Hurtado C. Effect of Diabetes on Clinical Outcomes in Patients with Peripheral Arterial Disease undergoing Lower Extremity Revascularization: A Systematic Review and Meta-Analysis. Journal Of Vascular Surgery 2025, 81: 1518-1528.e13. PMID: 40015609, DOI: 10.1016/j.jvs.2025.02.018.Peer-Reviewed Original ResearchLower extremity revascularizationPeripheral arterial diseaseHospital readmissionRelative riskDiabetes mellitusRandom-effects meta-analysisIncreased riskMeta-analysisAssociation of DMExtremity revascularizationMortality riskWound infectionRisk estimatesAssociated with diabetes mellitusClinical outcomesSystematic reviewArtery diseaseSystematic searchObservational studyWound infection riskReadmissionEffects of diabetesAmputationRiskHospitalAssociation between guideline-directed medical therapy and reintervention risk following peripheral vascular interventions in patients with peripheral artery disease
Callegari S, Romain G, Capuano I, Cleman J, Scierka L, Smolderen K, Mena-Hurtado C. Association between guideline-directed medical therapy and reintervention risk following peripheral vascular interventions in patients with peripheral artery disease. Vascular Medicine 2025, 30: 293-301. PMID: 39992181, DOI: 10.1177/1358863x251320347.Peer-Reviewed Original ResearchGuideline-directed medical therapyGuideline-directed medical therapy ratesPeripheral vascular interventionsPeripheral arterial diseaseReintervention outcomesReintervention riskMedical therapyArtery diseaseVascular interventionsAngiotensin receptor blockersCompeting risk analysisScore-matched cohortReceipt of statinsPost-PVIAngiotensin-converting enzymeReceptor blockersReinterventionMedicare outcomesMedication adherencePatientsRegistry dataTherapyOutcomesReceiptRisk
Clinical Trials
Current Trials
CRUSH PAD: Real-world Outcomes Following Use of the Shockwave Intravascular Lithotripsy (IVL) Technology in Calcified Common Femoral Lesions
HIC ID2000031113RolePrincipal InvestigatorPrimary Completion Date12/31/2023Recruiting ParticipantsGenderBothAge18+ yearsSCOPE-CLI: Shifting Care and Outcomes for Patients with Endangered limbs Critical Limb Ischemia
HIC ID2000028963RolePrincipal InvestigatorPrimary Completion Date09/30/2024Recruiting ParticipantsGenderBothAge19+ years
Academic Achievements & Community Involvement
News & Links
News
- June 02, 2025
New Professors in the Department of Internal Medicine
- February 10, 2025Source: American Heart Association: Professional Heart Daily
Understanding the Pain Experience and Treatment Considerations Along the Spectrum of Peripheral Artery Disease
- December 04, 2024
Integrating Behavioral Health Into Heart Care for a Healthier Heart: A Q&A with Matthew Burg, PhD
- November 05, 2024
Yale Researchers at American Heart Association Scientific Session 2024
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789 Howard Avenue
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