A pilot study of gray matter volume changes associated with paroxetine treatment and response in social anxiety disorder
Talati A, Pantazatos SP, Hirsch J, Schneier F. A pilot study of gray matter volume changes associated with paroxetine treatment and response in social anxiety disorder. Psychiatry Research 2015, 231: 279-285. PMID: 25659476, PMCID: PMC4363180, DOI: 10.1016/j.pscychresns.2015.01.008.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleGray MatterHumansMagnetic Resonance ImagingMaleParoxetinePhobic DisordersPilot ProjectsSelective Serotonin Reuptake InhibitorsTreatment OutcomeConceptsParoxetine treatmentSignificant gray matter reductionsGray matter volume changesAnxiety disordersNeuro-anatomical changesGray matter reductionsSocial anxiety disorderClinical responseLiebowitz Social Anxiety ScaleSymptom improvementRight thalamusVBM8 toolboxLeft thalamusSuccessful treatmentWeek 8Bilateral caudateControl groupGray matterDSM-IVSymptom severityLongitudinal changesPilot study