2015
A pilot study of gray matter volume changes associated with paroxetine treatment and response in social anxiety disorder
Talati A, Pantazatos SP, Hirsch J, Schneier F. A pilot study of gray matter volume changes associated with paroxetine treatment and response in social anxiety disorder. Psychiatry Research 2015, 231: 279-285. PMID: 25659476, PMCID: PMC4363180, DOI: 10.1016/j.pscychresns.2015.01.008.Peer-Reviewed Original ResearchConceptsParoxetine treatmentSignificant gray matter reductionsGray matter volume changesAnxiety disordersNeuro-anatomical changesGray matter reductionsSocial anxiety disorderClinical responseLiebowitz Social Anxiety ScaleSymptom improvementRight thalamusVBM8 toolboxLeft thalamusSuccessful treatmentWeek 8Bilateral caudateControl groupGray matterDSM-IVSymptom severityLongitudinal changesPilot study
2011
Brain tissue volume changes following weight gain in adults with anorexia nervosa
Roberto CA, Mayer LE, Brickman AM, Barnes A, Muraskin J, Yeung L, Steffener J, Sy M, Hirsch J, Stern Y, Walsh BT. Brain tissue volume changes following weight gain in adults with anorexia nervosa. International Journal Of Eating Disorders 2011, 44: 406-411. PMID: 21661001, PMCID: PMC3816503, DOI: 10.1002/eat.20840.Peer-Reviewed Original ResearchConceptsShort-term weight restorationWeight restorationGray matterAnorexia nervosaCerebrospinal fluidWhite matterBrain tissue volume changesWM volumeBrain volume deficitsUnderweight patientsAdult patientsControl womenTissue volume changesBrain volumeVolume deficitsPatientsAdult womenWeight gainSignificant increaseNervosaBody massWomenDeficitsLow levelsRestoration