Role of LFA‐1, ICAM‐1, VLA‐4 and VCAM‐1 in lymphocyte migration across retinal pigment epithelial monolayers in vitro
DEVINE L, LIGHTMAN S, GREENWOOD J. Role of LFA‐1, ICAM‐1, VLA‐4 and VCAM‐1 in lymphocyte migration across retinal pigment epithelial monolayers in vitro. Immunology 1996, 88: 456-462. PMID: 8774365, PMCID: PMC1456340, DOI: 10.1046/j.1365-2567.1996.d01-666.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlood-Retinal BarrierCD4-Positive T-LymphocytesCell Adhesion MoleculesCell Culture TechniquesCell MovementChemotaxis, LeukocyteEnzyme-Linked Immunosorbent AssayFlow CytometryIntercellular Adhesion Molecule-1Microscopy, ElectronPigment Epithelium of EyeRatsRats, Inbred StrainsVascular Cell Adhesion Molecule-1ConceptsBlood-retinal barrierRetinal pigment epitheliumLFA-1 betaICAM-1VCAM-1VLA-4Vascular endotheliumLymphocyte migrationAntigen-specific T cell linesAdhesion moleculesRetinal vascular endotheliumMigration of CD4Traffic of lymphocytesOcular inflammatory conditionsLFA-1 alphaVCAM-1 expressionRetinal pigment epithelial monolayerRPE cell monolayersT cell linesPosterior uveitisLymphocyte trafficInflammatory conditionsPosterior barrierCell adhesion moleculeIFN-gammaA Comparison of Lymphocyte Migration Across the Anterior and Posterior Blood-Retinal Barrier in Vitro
Devine L, Lightman S, Greenwood J. A Comparison of Lymphocyte Migration Across the Anterior and Posterior Blood-Retinal Barrier in Vitro. Advances In Behavioral Biology 1996, 46: 245-251. DOI: 10.1007/978-1-4757-9489-2_41.Peer-Reviewed Original ResearchBlood-retinal barrierCentral nervous systemRetinal pigment epitheliumImmune mediated diseasesSystemic immune systemVLA-4/VCAMTraffic of lymphocytesLFA-1/ICAMBlood-tissue barriersMediated diseasesCytokine activationLymphocyte migrationVascular endotheliumPigment epitheliumNervous systemImmune systemRPE monolayerAdhesion moleculesLymphocytesVascular endothelialReceptor-ligand pairingsCellular barriersEyesSeparate sitesVCAM