Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation
Xu D, Shen W, Guo R, Xue Y, Peng W, Sima J, Yang J, Sharov A, Srikantan S, Yang J, Fox D, Qian Y, Martindale JL, Piao Y, Machamer J, Joshi SR, Mohanty S, Shaw AC, Lloyd TE, Brown GW, Ko MS, Gorospe M, Zou S, Wang W. Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation. Nature Neuroscience 2013, 16: 1238-1247. PMID: 23912945, PMCID: PMC3853347, DOI: 10.1038/nn.3479.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, Genetically ModifiedCells, CulturedChickensDNA Topoisomerases, Type IDrosophilaDrosophila ProteinsEmbryo, MammalianEyeFragile X Mental Retardation ProteinGene Expression RegulationHumansMiceMice, Inbred C57BLNerve Tissue ProteinsNeurogenesisNeuromuscular JunctionNeuronsRNA-Binding ProteinsTransfection