2024
High rates of deferring antiretroviral treatment for patients with HIV and substance use disorders: Results from a national sample of HIV physicians in Ukraine
Ottesen T, Wickersham J, Lawrence J, Antoniak S, Zezuilin O, Polonsky M, Antonyak S, Rozanova J, Dvoriak S, Pykalo I, Filippovych M, Altice F. High rates of deferring antiretroviral treatment for patients with HIV and substance use disorders: Results from a national sample of HIV physicians in Ukraine. PLOS ONE 2024, 19: e0305086. PMID: 39028735, PMCID: PMC11259278, DOI: 10.1371/journal.pone.0305086.Peer-Reviewed Original ResearchConceptsAntiretroviral therapy prescriptionAntiretroviral therapyCD4 countSubstance use disordersIncreased levels of stigmaNational sampleLevel of stigmaIndependent of risk groupSuboptimal antiretroviral therapyInitiate antiretroviral therapyPopulation of peopleHIV expertsHIV incidenceHIV physiciansHIV treatmentKey populationsTransgender womenAntiretroviral treatmentFeeling thermometerDrinking alcoholSex workersPhysiciansSex partnersPWHRisk groupsHIV Activist Identity, Commitment, and Orientation Scale (HAICOS): Psychometric Evaluation to Assess Clinician’s Propensity Towards HIV Activism in Malaysia
Chong N, Azwa I, Hassan A, Mousavi M, Wong P, Ng R, Saifi R, Basri S, Omar S, Walters S, Collier Z, Haddad M, Altice F, Kamarulzaman A, Earnshaw V. HIV Activist Identity, Commitment, and Orientation Scale (HAICOS): Psychometric Evaluation to Assess Clinician’s Propensity Towards HIV Activism in Malaysia. AIDS And Behavior 2024, 28: 2780-2792. PMID: 38806844, DOI: 10.1007/s10461-024-04381-4.Peer-Reviewed Original ResearchConceptsExploratory factor analysisHIV-related stigmaIntra-class correlation coefficientPrimary care physiciansTest-retest reliabilityCronbach's alpha valuesOrientation ScaleCare physiciansStigma-relatedPsychometric evaluationHIV treatmentHIV activityAlpha valuesPsychometric qualitiesActivist identitiesHIVClinical practiceFactor analysisCliniciansCorrelation coefficientDay-to-dayStructured activitiesCronbachStigmaPhysicians
2022
Mobile Health Technology Use and the Acceptability of an mHealth Platform for HIV Prevention Among Men Who Have Sex With Men in Malaysia: Cross-sectional Respondent-Driven Sampling Survey
Shrestha R, Maviglia F, Altice FL, DiDomizio E, Khati A, Mistler C, Azwa I, Kamarulzaman A, Halim MAA, Wickersham JA. Mobile Health Technology Use and the Acceptability of an mHealth Platform for HIV Prevention Among Men Who Have Sex With Men in Malaysia: Cross-sectional Respondent-Driven Sampling Survey. Journal Of Medical Internet Research 2022, 24: e36917. PMID: 35877172, PMCID: PMC9361153, DOI: 10.2196/36917.Peer-Reviewed Original ResearchConceptsHIV prevention informationHIV preventionDrug usePrevention informationMalaysian menMHealth platformHIV risk-related behaviorsHIV prevention toolHIV prevention servicesSexual activityReceptive anal sexMobile health interventionsHIV prevention effortsUse of mHealthIllicit drug useSexualized drug useCross-sectional surveyAcceptability of mHealthHealth technology useSelf-administered questionnaireRespondent-driven samplingHealth-related informationSuboptimal engagementDearth of evidencePrevention services
2021
Acceptability of an mHealth App That Provides Harm Reduction Services Among People Who Inject Drugs: Survey Study
Shelby T, Zhou X, Barber D, Altice F. Acceptability of an mHealth App That Provides Harm Reduction Services Among People Who Inject Drugs: Survey Study. Journal Of Medical Internet Research 2021, 23: e25428. PMID: 34259640, PMCID: PMC8319773, DOI: 10.2196/25428.Peer-Reviewed Original ResearchMeSH KeywordsHarm ReductionHIV InfectionsHumansMaleMiddle AgedMobile ApplicationsPharmaceutical PreparationsSubstance Abuse, IntravenousSurveys and QuestionnairesTelemedicineConceptsSyringe services programHarm reduction servicesReduction servicesSecondary outcomesMHealth appsParticipant characteristicsHarm reduction needsHome deliveryMost participantsRespondent-driven samplingPrimary outcomeSuboptimal accessIndependent correlatesMedical recordsDrug injectionMobile health appsPWIDSummary scoresMedication remindersSSP usePoisson regressionUnstable housingVulnerable populationsSyringe deliveryHealth appsPreferences for pre-exposure prophylaxis among U.S. military men who have sex with men: results of an adaptive choice based conjoint analysis study
Gutierrez JI, Dubov A, Altice FL, Vlahov D. Preferences for pre-exposure prophylaxis among U.S. military men who have sex with men: results of an adaptive choice based conjoint analysis study. Military Medical Research 2021, 8: 32. PMID: 34006328, PMCID: PMC8132436, DOI: 10.1186/s40779-021-00323-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultBayes TheoremConsumer BehaviorHIV InfectionsHumansMaleMilitary PersonnelPre-Exposure ProphylaxisSexual and Gender MinoritiesSurveys and QuestionnairesUnited StatesConceptsDaily tabletHuman immunodeficiency virus (HIV) infectionMilitary healthcare settingsImmunodeficiency virus infectionPre-exposure prophylaxisU.S. military menTelehealth visitsResultsA totalVirus infectionProvider typeUtility scoresPrEP programHealthcare settingsMental healthMilitary providersProphylaxisMenSexInjectionConjoint analysis studyMilitary menService deliverySocial media groupsMedia groupsMedicationsWillingness to initiate pre-exposure prophylaxis (PrEP) and its use among opioid-dependent individuals in drug treatment
Ni Z, Altice FL, Wickersham JA, Copenhaver MM, DiDomizio EE, Nelson LE, Shrestha R. Willingness to initiate pre-exposure prophylaxis (PrEP) and its use among opioid-dependent individuals in drug treatment. Drug And Alcohol Dependence 2021, 219: 108477. PMID: 33422864, PMCID: PMC7946167, DOI: 10.1016/j.drugalcdep.2020.108477.Peer-Reviewed Original ResearchConceptsOpioid-dependent individualsPre-exposure prophylaxisPrEP useHIV riskHealthcare providersSex-related risk behaviorsMultivariable logistic regression analysisAwareness of PrEPUrban methadone clinicMultiple logistic regressionDisproportionate HIV burdenLogistic regression analysisCross-sectional surveyHIV burdenHIV infectionHIV testingIndependent correlatesMethadone clinicsDrug treatmentRisk behaviorsLogistic regressionPrEPPrevious useHigher likelihoodProphylaxis
2020
Response to the COVID-19 Outbreak in Urban Settings in China
Ni Z, Lebowitz ER, Zou Z, Wang H, Liu H, Shrestha R, Zhang Q, Hu J, Yang S, Xu L, Wu J, Altice FL. Response to the COVID-19 Outbreak in Urban Settings in China. Journal Of Urban Health 2020, 98: 41-52. PMID: 33258088, PMCID: PMC7703725, DOI: 10.1007/s11524-020-00498-8.Peer-Reviewed Original Research
2019
Evaluation of HIV risk and outcomes in a nationally representative sample of incarcerated women in Azerbaijan, Kyrgyzstan, and Ukraine
Ranjit YS, Azbel L, Krishnan A, Altice FL, Meyer JP. Evaluation of HIV risk and outcomes in a nationally representative sample of incarcerated women in Azerbaijan, Kyrgyzstan, and Ukraine. AIDS Care 2019, 31: 793-797. PMID: 30701981, PMCID: PMC6510603, DOI: 10.1080/09540121.2019.1573969.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntiretroviral Therapy, Highly ActiveAzerbaijanCommunicable DiseasesComorbidityContinuity of Patient CareFemaleHealth Services AccessibilityHepatitis CHIV InfectionsHumansKyrgyzstanMaleMental DisordersMiddle AgedPrevalencePrisonersPrisonsSubstance-Related DisordersSurveys and QuestionnairesSyphilisUkraineConceptsAlcohol use disorderAntiretroviral therapyHIV preventionHIV riskHIV care continuumCells/μLHigh-risk groupComorbid substance useEffective HIV preventionGlobal HIV preventionHigh rateHepatitis CIncarcerated womenHIV testingHIV incidenceHIV prevalencePsychiatric comorbidityDrug injectionRepresentative sampleCare continuumRisk groupsPsychiatric disordersMost womenUse disordersTreatment interventionsRetention in clinical trials after prison release: results from a clinical trial with incarcerated men with HIV and opioid dependence in Malaysia
Chandra DK, Bazazi AR, Solim M, Kamarulzaman A, Altice FL, Culbert GJ. Retention in clinical trials after prison release: results from a clinical trial with incarcerated men with HIV and opioid dependence in Malaysia. HIV Research & Clinical Practice 2019, 20: 12-23. PMID: 31303149, PMCID: PMC6698147, DOI: 10.1080/15284336.2019.1603433.Peer-Reviewed Original ResearchConceptsClinical trialsStudy visitHIV clinical trialsOpioid dependenceMethadone initiationStudy retentionHolistic Health Recovery ProgramPrison releaseHIV risk reduction interventionsRisk reduction interventionsIncarcerated menStandard careMethadone treatmentReduction interventionsStudy participantsFactorial trialHIVBehavioral interventionsTrialsVisitsMost participantsInterventionMenCommunity reentryRecovery program
2018
Evaluating Physicians’ Intention to Discriminate Against Patients Living with HIV in Malaysia
Tee YC, Earnshaw VA, Altice FL, Jin H, Kamarulzaman A, Wickersham JA. Evaluating Physicians’ Intention to Discriminate Against Patients Living with HIV in Malaysia. AIDS And Behavior 2018, 23: 1039-1047. PMID: 30560483, PMCID: PMC6459712, DOI: 10.1007/s10461-018-2362-4.Peer-Reviewed Original ResearchConceptsStigma-related constructsMajor university hospitalClasses of patientsCross-sectional online surveyNon-surgical specialtiesMore HIVSocio-demographic characteristicsUniversity HospitalHIV preventionTreatment strategiesPWHClinical experienceHIVBetter carePhysiciansMultivariate linear regressionMedical settingsInternational HIV preventionMost participantsLinear regressionPatientsCarePresent studyParticipantsStigmaOptimizing access to PrEP based on MSM preferences: results of a discrete choice experiment
Dubov A, Ogunbajo A, Altice FL, Fraenkel L. Optimizing access to PrEP based on MSM preferences: results of a discrete choice experiment. AIDS Care 2018, 31: 545-553. PMID: 30554519, PMCID: PMC6408226, DOI: 10.1080/09540121.2018.1557590.Peer-Reviewed Original ResearchConceptsYoung MSMInjectable PrEPPrEP uptakeUptake of PrEPPre-exposure prophylaxisHigh HIV burdenMSM of colorMSM preferencesPrEP administrationDaily PrEPPrEP initiationHIV burdenDemand PrEPConsultation visitMSMPrEP programPrEPLatent class analysisDelivery programsMenGroupClass analysisStructural barriersLow levelsUptakeHIV Sero-Status Non-disclosure Among HIV-Infected Opioid-Dependent Individuals: The Roles of HIV-Related Stigma, Risk Behavior, and Social Support
Shrestha R, Altice FL, Sibilio B, Copenhaver MM. HIV Sero-Status Non-disclosure Among HIV-Infected Opioid-Dependent Individuals: The Roles of HIV-Related Stigma, Risk Behavior, and Social Support. Journal Of Community Health 2018, 44: 112-120. PMID: 30043195, PMCID: PMC6330145, DOI: 10.1007/s10900-018-0560-7.Peer-Reviewed Original ResearchConceptsOpioid-dependent individualsOpioid-dependent patientsHIV statusFamily/friendsSexual partnersHIV disclosureHIV sero-status disclosureRisk behaviorsHIV sero statusAntiretroviral therapy adherenceHigh-risk HIVRole of HIVMultivariable logistic regressionSubstance abuse treatment settingsHIV risk behaviorsInconsistent condom useMultiple sex partnersSocial supportHigh HIVSero statusHIV transmissionTherapy adherenceIndependent correlatesHIV riskHIV stigmaPrevalence, Diagnosis, and Treatment Rates of Mood Disorders among Opioid Users under Criminal Justice Supervision
Mbaba M, Brown SE, Wooditch A, Kiss M, Murphy A, Kumari S, Taxman F, Altice F, Lawson WB, Springer SA. Prevalence, Diagnosis, and Treatment Rates of Mood Disorders among Opioid Users under Criminal Justice Supervision. Substance Use & Misuse 2018, 53: 1519-1528. PMID: 29333954, PMCID: PMC6432769, DOI: 10.1080/10826084.2017.1416400.Peer-Reviewed Original ResearchMeSH KeywordsAdultBipolar DisorderComorbidityCriminal LawDepressive DisorderFemaleHumansMaleMiddle AgedOpioid-Related DisordersPrevalenceSelf ReportSurveys and QuestionnairesConceptsPatient Health Questionnaire-9Mood disordersBipolar disorderOpioid usersAddiction Severity Index-LiteOpioid use treatmentCriminal justice supervisionOpioid-dependent individualsSelf-reported mood disordersOpioid-dependent populationsComprehensive psychiatric careAdverse health consequencesLarger parent studyLifetime suicide attemptsHigh rateQuestionnaire-9Positive screenJustice-involved individualsSevere depressionTreatment utilizationGeneral U.S.Psychiatric careControl trialParent studyPsychiatric disorders
2017
Strategies to Implement Pre-exposure Prophylaxis with Men Who Have Sex with Men in Ukraine
Dubov A, Fraenkel L, Yorick R, Ogunbajo A, Altice FL. Strategies to Implement Pre-exposure Prophylaxis with Men Who Have Sex with Men in Ukraine. AIDS And Behavior 2017, 22: 1100-1112. PMID: 29214409, PMCID: PMC10866617, DOI: 10.1007/s10461-017-1996-y.Peer-Reviewed Original ResearchMeSH KeywordsAdultHIV InfectionsHomosexuality, MaleHumansImplementation ScienceMalePatient PreferencePre-Exposure ProphylaxisSurveys and QuestionnairesUkraineConceptsPre-exposure prophylaxisLow self-perceived riskSelf-perceived riskInjectable PrEPMSM preferencesPrEP administrationPrEP initiationDaily PrEPHIV prevalencePatient preferencesRisk groupsRisk populationsMedical carePrEPLatent class analysisProphylaxisMenDelivery programsMSMUkrainian menProgram deliverySexGroupClass analysisSuccessful deliveryHepatitis C virus treatment as prevention in an extended network of people who inject drugs in the USA: a modelling study
Zelenev A, Li J, Mazhnaya A, Basu S, Altice FL. Hepatitis C virus treatment as prevention in an extended network of people who inject drugs in the USA: a modelling study. The Lancet Infectious Diseases 2017, 18: 215-224. PMID: 29153265, PMCID: PMC5860640, DOI: 10.1016/s1473-3099(17)30676-x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAntiviral AgentsChemopreventionCitiesComputer SimulationDisease Transmission, InfectiousFemaleHepatitis CHumansMaleMiddle AgedModels, StatisticalPrevalenceSubstance Abuse, IntravenousSurveys and QuestionnairesTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsBaseline HCV prevalenceHepatitis C virusHCV prevalenceInjection partnersPrevention strategiesTreatment coverageTransmission of HCVHepatitis C virus (HCV) treatmentHCV elimination strategySuccessful HCV treatmentC virus treatmentInjection drug usersHCV treatment coverageAdditional network memberHCV treatmentActing antiviralsC virusChronic infectionVirus treatmentDrug usersPrevalenceDrug abuseDrugsNational InstitutePreventionMeasuring Acceptability and Preferences for Implementation of Pre-Exposure Prophylaxis (PrEP) Using Conjoint Analysis: An Application to Primary HIV Prevention Among High Risk Drug Users
Shrestha R, Karki P, Altice FL, Dubov O, Fraenkel L, Huedo-Medina T, Copenhaver M. Measuring Acceptability and Preferences for Implementation of Pre-Exposure Prophylaxis (PrEP) Using Conjoint Analysis: An Application to Primary HIV Prevention Among High Risk Drug Users. AIDS And Behavior 2017, 22: 1228-1238. PMID: 28695388, PMCID: PMC5762432, DOI: 10.1007/s10461-017-1851-1.Peer-Reviewed Original ResearchConceptsPre-exposure prophylaxisSex-related risk behaviorsHigh-risk drug usersAcceptability of PrEPHigh-risk PWUDPrimary HIV preventionHIV prevention approachesDrug treatment settingsKey risk populationsHIV-negative PWUDHigh acceptabilityHIV clinicPrEP acceptabilityHIV testingPrEP uptakeMethadone clinicsHIV preventionRisk populationsSide effectsTreatment settingsDrug usersPrEP attributesRisk behaviorsPrEPUnderserved populationsAn explanatory factor analysis of a brief self-report scale to detect neurocognitive impairment among HIV-positive men who have sex with men and transgender women in Peru
Weikum D, Shrestha R, Ferro EG, Vagenas P, Copenhaver M, Spudich S, Alpert MD, Cabello R, Lama JR, Sanchez J, Altice FL. An explanatory factor analysis of a brief self-report scale to detect neurocognitive impairment among HIV-positive men who have sex with men and transgender women in Peru. AIDS Care 2017, 29: 1297-1301. PMID: 28449599, PMCID: PMC6337065, DOI: 10.1080/09540121.2017.1322681.Peer-Reviewed Original ResearchConceptsHIV-positive menNeuropsychological Impairment ScaleNeurocognitive impairmentTransgender womenAntiretroviral therapyHIV-positive MSMPoor clinical outcomeHIV risk behaviorsClinical care settingsHealth-related outcomesExploratory factor analysisART adherenceClinical outcomesPatient populationCare settingsImpairment ScaleRisk behaviorsImpairmentMenPrincipal axis factoringSelf-report scalesOrthogonal varimax rotationWomenBrief self-report scaleOutcomesA Moderated Mediation Model of HIV-Related Stigma, Depression, and Social Support on Health-Related Quality of Life among Incarcerated Malaysian Men with HIV and Opioid Dependence
Shrestha R, Copenhaver M, Bazazi AR, Huedo-Medina TB, Krishnan A, Altice FL. A Moderated Mediation Model of HIV-Related Stigma, Depression, and Social Support on Health-Related Quality of Life among Incarcerated Malaysian Men with HIV and Opioid Dependence. AIDS And Behavior 2017, 21: 1059-1069. PMID: 28108877, PMCID: PMC5344717, DOI: 10.1007/s10461-017-1693-x.Peer-Reviewed Original Research
2016
Co-calibration of two self-reported measures of adherence to antiretroviral therapy
Nance RM, Delaney JA, Golin CE, Wechsberg WM, Cunningham C, Altice F, Christopoulos K, Knight K, Quan V, Gordon MS, Springer S, Young J, Crane PK, Mayer KH, Mugavero MJ, Del Rio C, Kronmal RA, Crane HM. Co-calibration of two self-reported measures of adherence to antiretroviral therapy. AIDS Care 2016, 29: 464-468. PMID: 27910703, PMCID: PMC5291764, DOI: 10.1080/09540121.2016.1263721.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsCalibrationFemaleHIV InfectionsHumansLinear ModelsMaleMedication AdherenceMiddle AgedRegression AnalysisSelf ReportSurveys and QuestionnairesVisual Analog ScaleConceptsVisual analog scaleAntiretroviral therapyAdherence measuresAIDS Clinical Trials Group questionnaireHigh-risk vulnerable populationsVulnerable populationsCare cohortAnalog scaleVAS scaleHIV StudyAdherence dataClinical successConsortium studyGroup questionnaireTherapyDosesSelf-report measuresAdherenceAn Exploratory Factor Analysis of a Brief Self-Report Scale to Detect Neurocognitive Impairment Among Participants Enrolled in Methadone Maintenance Therapy
Copenhaver M, Shrestha R, Wickersham JA, Weikum D, Altice FL. An Exploratory Factor Analysis of a Brief Self-Report Scale to Detect Neurocognitive Impairment Among Participants Enrolled in Methadone Maintenance Therapy. Journal Of Substance Use And Addiction Treatment 2016, 63: 61-65. PMID: 26879859, PMCID: PMC4775373, DOI: 10.1016/j.jsat.2016.01.002.Peer-Reviewed Original ResearchConceptsMethadone maintenance therapyNeuropsychological Impairment ScaleNeurocognitive impairmentMaintenance therapySex-related HIV risk behaviorsHIV risk behaviorsClinical care settingsNeuro-cognitive impairmentExploratory factor analysisCare settingsImpairment ScaleRisk behaviorsAddiction treatmentBrief self-report scaleImpairmentSelf-report measuresSelf-report scalesPatientsPrincipal axis factoringCognitive functioningTherapyFactor analysisOrthogonal varimax rotationPresent studyPotential utility