2021
Standardised quantification of coronary inflammation using cardiac computed tomography: The Fat Attenuation Index Score (FAI-Score)
Oikonomou E, Schottlander D, Antonopoulos A, Marwan M, Kotanidis C, Kluner L, Shirodaria C, Channon K, Neubauer S, Desai M, Deanfield J, Achenbach S, Antoniades C. Standardised quantification of coronary inflammation using cardiac computed tomography: The Fat Attenuation Index Score (FAI-Score). European Journal Of Preventive Cardiology 2021, 28: zwab061.451. DOI: 10.1093/eurjpc/zwab061.451.Peer-Reviewed Original ResearchCoronary inflammationRight coronaryFAI scoreCardiac mortalityPercentile curvesPrognostic valueCoronary artery disease indexHigh-risk plaque featuresCardiovascular prevention strategiesTraditional risk factorsCardiac computed tomographyBritish Heart FoundationFAI valuesMedian followInflammatory burdenCardiovascular riskAtherosclerotic changesCardiac deathAnterior descendingCircumflex arteryCoronary territoriesRisk stratificationPlaque featuresCoronary arteryMean age
2020
Pericoronary fat radiomic profile (FRP) predicts long-term cardiac risk in individuals with calcium score below 100 on coronary computed tomography angiography
Kotanidis C, Oikonomou E, Williams M, Thomas S, Thomas K, Lyasheva M, Antonopoulos A, Dweck M, Shirodaria C, Neubauer S, Channon K, Newby D, Antoniades C. Pericoronary fat radiomic profile (FRP) predicts long-term cardiac risk in individuals with calcium score below 100 on coronary computed tomography angiography. European Heart Journal 2020, 41: ehaa946.0181. DOI: 10.1093/ehjci/ehaa946.0181.Peer-Reviewed Original ResearchCoronary artery calciumCoronary artery diseaseHigh-risk plaquesAdipose tissue compositionArtery calciumCAC scoreCardiac riskTomography angiographyStudy populationLong-term cardiac riskMajor adverse cardiac eventsObstructive coronary artery diseaseSCOT-HEART trialAdverse cardiac eventsRisk of MACEAdverse clinical eventsTraditional risk factorsChronic vascular inflammationLow CAC scoresPericoronary adipose tissueCardiovascular risk assessmentLow-risk populationCox regression modelBritish Heart FoundationBiomedical Research Centre