2021
N‐Terminal Pro‐B‐Type Natriuretic Peptide as a Biomarker for the Severity and Outcomes With COVID‐19 in a Nationwide Hospitalized Cohort
O’Donnell C, Ashland M, Vasti E, Lu Y, Chang A, Wang P, Daniels L, de Lemos J, Morrow D, Rodriguez F, O’Brien C. N‐Terminal Pro‐B‐Type Natriuretic Peptide as a Biomarker for the Severity and Outcomes With COVID‐19 in a Nationwide Hospitalized Cohort. Journal Of The American Heart Association 2021, 10: e022913. PMID: 34889112, PMCID: PMC9075235, DOI: 10.1161/jaha.121.022913.Peer-Reviewed Original ResearchConceptsElevated NT-proBNPCardiovascular risk factorsNT-proBNPHospital mortalityHeart failureRisk factorsCOVID-19N-terminal pro-B-type natriuretic peptidePro-B-type natriuretic peptideElevated NT-proBNP concentrationsElevated NT-proBNP levelsIntensive care unit admissionLog-transformed NT-proBNPMajor adverse cardiac eventsMore cardiovascular risk factorsPrior heart failureAdverse cardiac eventsCare unit admissionNT-proBNP levelsNT-proBNP concentrationsObservational cohort studyShorter median timeRisk of deathUnit admissionCardiac events
2020
Breast cancer induces systemic immune changes on cytokine signaling in peripheral blood monocytes and lymphocytes
Wang L, Simons D, Lu X, Tu T, Avalos C, Chang A, Dirbas F, Yim J, Waisman J, Lee P. Breast cancer induces systemic immune changes on cytokine signaling in peripheral blood monocytes and lymphocytes. EBioMedicine 2020, 52: 102631. PMID: 31981982, PMCID: PMC6992943, DOI: 10.1016/j.ebiom.2020.102631.Peer-Reviewed Original ResearchConceptsSystemic immune changesPeripheral blood monocytesBreast Cancer Research FoundationBreast Cancer Research ProgramBC patientsImmune changesBlood monocytesPeripheral bloodImmune cellsNon-metastatic BC patientsPeripheral blood immune cellsPeripheral blood T cellsCancer patients' peripheral bloodBlood immune cellsBreast cancer patientsOverall immune statusBlood T cellsPatients' peripheral bloodTumor-infiltrating macrophagesDefense Breast Cancer Research ProgramCancer Research ProgramCancer Research FoundationConcurrent cytokineLocalized diseaseImmune status