Environmental factors, such as air pollution, extreme temperatures, hurricanes, wildfires, and other climate events, can contribute to or worsen cardiovascular conditions. Yale School of Medicine faculty members offer insights into how weather and air pollution affect the heart, and share guidelines to protect patient health.
Andrew Y. Chang, MD, PhD
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About
Titles
Assistant Professor of Medicine (Cardiovascular Medicine)
Affiliated Faculty, Yale Institute for Global Health; Affiliated Faculty, Yale School of Public Health
Biography
Dr. Chang is an Assistant Professor of Cardiovascular Medicine at the Yale University School of Medicine with clinical expertise in cardiology and advanced echocardiography (cardiac ultrasound), and research interests in environmental health. His clinical activities include general cardiology, cardiac imaging, and the use of echocardiography for guiding minimally-invasive structural heart procedures such as transcatheter valve replacements. His investigative work focuses on understanding how climatic and environmental factors impact heart health and how we may leverage digital data sources to detect such harms while exploring risk mitigation strategies for their effects.
Dr. Chang completed his undergraduate training at Yale University, then attended Stanford for medical school and internal medicine residency, where he served as Chief Resident. He completed his cardiology fellowship and PhD in Epidemiology and Clinical Research at Stanford, then pursued an advanced fellowship in echocardiography at the University of California San Francisco.
Last Updated on September 27, 2026.
Appointments
Cardiovascular Medicine
Assistant ProfessorPrimary
Other Departments & Organizations
Education & Training
- PhD
- Stanford University, Epidemiology and Clinical Research (2024)
- Advanced Fellowship
- University of California San Francisco (2024)
- Fellowship
- Stanford University Hospital (2021)
- MS
- Stanford University, Epidemiology and Clinical Research (2018)
- Chief Resident
- Stanford University Hospital (2017)
- Residency
- Stanford University Hospital (2016)
- MD
- Stanford University (2013)
- BS
- Yale University, Molecular, Cellular and Developmental Biology (2008)
Research
Publications
Featured Publications
Aging Hearts in a Hotter, More Turbulent World: The Impacts of Climate Change on the Cardiovascular Health of Older Adults
Chang A, Tan A, Nadeau K, Odden M. Aging Hearts in a Hotter, More Turbulent World: The Impacts of Climate Change on the Cardiovascular Health of Older Adults. Current Cardiology Reports 2022, 24: 749-760. PMID: 35438387, PMCID: PMC9017408, DOI: 10.1007/s11886-022-01693-6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsThe impact of novel coronavirus COVID‐19 on noncommunicable disease patients and health systems: a review
Chang A, Cullen M, Harrington R, Barry M. The impact of novel coronavirus COVID‐19 on noncommunicable disease patients and health systems: a review. Journal Of Internal Medicine 2020, 289: 450-462. PMID: 33020988, PMCID: PMC7675448, DOI: 10.1111/joim.13184.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAssociation of PM2.5 With Cardiac Mechanics Using Speckle-Tracking Echocardiography in the Cardiovascular Health Study
Chang A, Kaufman J, Tan A, Shah S, Patel R, Margolis H, Psaty B, Gardin J, Al-Kindi S, Austin T, Odden M. Association of PM2.5 With Cardiac Mechanics Using Speckle-Tracking Echocardiography in the Cardiovascular Health Study. JACC Cardiovascular Imaging 2025, 18: 741-743. PMID: 40243973, PMCID: PMC13570564, DOI: 10.1016/j.jcmg.2025.01.016.Peer-Reviewed Original ResearchThis study investigates how long-term exposure to fine particulate air pollution (PM2.5) affects heart function in older adults, showing subtle myocardial strain impairments linked to higher exposure levels.Cross‐Sectional Association of Ground‐Level Ozone and Nitrogen Dioxide With Cardiac Mechanics Using Speckle‐Tracking Echocardiography in the Cardiovascular Health Study
Chang A, Kaufman J, Shah S, Tan A, Patel R, Margolis H, Psaty B, Gardin J, Al‐Kindi S, Austin T, Bell M, Chen K, Odden M. Cross‐Sectional Association of Ground‐Level Ozone and Nitrogen Dioxide With Cardiac Mechanics Using Speckle‐Tracking Echocardiography in the Cardiovascular Health Study. Echocardiography 2025, 42: e70330-e70330. PMID: 41146536, PMCID: PMC12664112, DOI: 10.1111/echo.70330.Peer-Reviewed Original ResearchWorking Toward a More Environmentally Sustainable Echocardiography Lab: Present Considerations and Future Directions.
Chang AY, Bellumkonda L, McNamara RL, Yao Y, Zoghbi WA, Rajagopalan S, Al-Kindi S. Working Toward a More Environmentally Sustainable Echocardiography Lab: Present Considerations and Future Directions. J Am Soc Echocardiogr 2026 PMID: 42731736, DOI: 10.1016/j.echo.2026.08.025.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2026
Noninvasive Diagnosis of Heart Failure With Preserved Ejection Fraction Using the Left Atrioventricular Coupling Index.
Janssen-Telders C, Ābele J, Meijboom LJ, de Groot JR, Guglielmo M, Hameed A, Alabed S, Charalampopoulos A, Condliffe R, Kiely DG, Swift AJ, de Man FS, Handoko ML, ASPIRE consortium. Noninvasive Diagnosis of Heart Failure With Preserved Ejection Fraction Using the Left Atrioventricular Coupling Index. J Am Heart Assoc 2026, e050411. PMID: 42669904, DOI: 10.1161/JAHA.125.050411.Peer-Reviewed Original ResearchHigh Risk, High Reward: The Value of Transcatheter Aortic Valve Replacement in Low-Flow, Low-Gradient Aortic Stenosis.
Zheng J, Fearon W, Chang A. High Risk, High Reward: The Value of Transcatheter Aortic Valve Replacement in Low-Flow, Low-Gradient Aortic Stenosis. Journal Of The American Heart Association 2026, e053204. PMID: 42669920, DOI: 10.1161/jaha.126.053204.Commentaries, Editorials and LettersIntersection of Climate and Environmental Change and Priority Health Outcomes Across the Life Course: Working Group 1 Report from the “Agriculture and Diet: Value Added for Nutrition, Translation, and Adaptation in a Global Ecology” (ADVANTAGE) Project
Ebi K, Krebs N, Bellows A, Shankar K, Chang A, Kleinman R, Raiten D. Intersection of Climate and Environmental Change and Priority Health Outcomes Across the Life Course: Working Group 1 Report from the “Agriculture and Diet: Value Added for Nutrition, Translation, and Adaptation in a Global Ecology” (ADVANTAGE) Project. Advances In Nutrition 2026, 17: 100673. PMID: 42276449, PMCID: PMC13334813, DOI: 10.1016/j.advnut.2026.100673.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsA cluster-randomized trial of labelled cash transfers for uptake of care for chronic conditions among middle-aged and older adults in Burkina Faso
Geldsetzer P, Chang A, Junghanns J, Bountogo M, Ouermi L, Zabre P, Sié A, Harkare H, Theilmann M, Harling G, Jacques A, Bärnighausen T. A cluster-randomized trial of labelled cash transfers for uptake of care for chronic conditions among middle-aged and older adults in Burkina Faso. Nature Human Behaviour 2026, 10: 1047-1059. PMID: 42010350, DOI: 10.1038/s41562-026-02453-0.Peer-Reviewed Original Research
2025
All That Glitters Is Not Gold Exploring Metal Exposures as Risk Factors for Incident Heart Failure
Narula S, Chang A. All That Glitters Is Not Gold Exploring Metal Exposures as Risk Factors for Incident Heart Failure. JACC Heart Failure 2025, 13: 102629. PMID: 40845616, DOI: 10.1016/j.jchf.2025.102629.Commentaries, Editorials and Letters
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Cardiovascular Medicine
789 Howard Ave., Section of Cardiovascular Medicine
New Haven, CT 06519
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