IL6 Signaling in Peripheral Blood T Cells Predicts Clinical Outcome in Breast Cancer
Wang L, Miyahira A, Simons D, Lu X, Chang A, Wang C, Suni M, Maino V, Dirbas F, Yim J, Waisman J, Lee P. IL6 Signaling in Peripheral Blood T Cells Predicts Clinical Outcome in Breast Cancer. Cancer Research 2017, 77: 1119-1126. PMID: 27879265, PMCID: PMC5334262, DOI: 10.1158/0008-5472.can-16-1373.Peer-Reviewed Original ResearchConceptsPeripheral blood T cellsBreast cancer patientsBlood T cellsCancer patientsT cellsIL6 levelsWorse relapse-free survivalPlasma IL6 levelsCancer cellsRelapse-free survivalSerum IL6 levelsAnti-inflammatory propertiesHost immune responseInvolved downregulationClinical outcomesPredictive biomarkersImmune responsePleiotropic cytokinePatientsIL6Cancer ResCancer progressionSurvivalDiagnosisCells