Haidong Lu, PhD
Assistant Professor of Internal MedicineDownloadHi-Res Photo
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Appointments
General Internal Medicine
Primary
Chronic Disease Epidemiology
Secondary
Contact Info
About
Titles
Assistant Professor of Internal Medicine
Biography
Dr. Haidong Lu is an epidemiologist and methodologist who is passionate about bridging the disciplines of epidemiology, statistics, data science, population health, and clinical research. His research focuses on leveraging appropriate health data science techniques to draw causal inferences from observational data (e.g., electronic health records). Through this approach, he strives to generate accurate and impactful real-world evidence that informs clinical and regulatory decision-making. In addition to observational studies, he is dedicated to enhancing methodologies for analyzing randomized controlled trials, particularly in addressing challenges related to non-compliance and generalizability. Dr. Lu is also interested in artificial intelligence in learning health systems. His current substantive research interests center around substance use and pharmacoepidemiology. Dr. Lu earned a PhD in Epidemiology (major) and Biostatistics (minor) from UNC Gillings School of Global Public Health, and a master's degree from Johns Hopkins Bloomberg School of Public Health. He is also clinically trained with a degree in pharmacy, further reinforcing his diverse and extensive background in health-related fields.
Last Updated on June 03, 2025.
Appointments
General Internal Medicine
Assistant ProfessorPrimaryChronic Disease Epidemiology
Assistant ProfessorSecondary
Other Departments & Organizations
Education & Training
- PhD
- The University of North Carolina at Chapel Hill
Research
Overview
Medical Research Interests
Addiction Medicine; Aging; Alcohol-Related Disorders; Biostatistics; Causality; Data Science; Drug Overdose; Epidemiologic Methods; Epidemiology; Health Policy; Health Services Research; HIV; Observational Study; Pharmacoepidemiology; Public Health; Statistics; Substance-Related Disorders
Public Health Interests
Aging; Epidemiology Methods; GIS/Disease Mapping; HIV/AIDS; Substance Use, Addiction; Survival Analysis; Pharmacoepidemiology
ORCID
0000-0002-7908-2517- View Lab Website
Yale PEW
Research at a Glance
Yale Co-Authors
Frequent collaborators of Haidong Lu's published research.
Publications Timeline
A big-picture view of Haidong Lu's research output by year.
Research Interests
Research topics Haidong Lu is interested in exploring.
Gregg Gonsalves, PhD
David Fiellin, MD
David S. Fink, PhD
Lauretta Grau, PhD
Benjamin Howell, MD, MPH, MHS
Christopher T Rentsch, PhD, FISPE
41Publications
751Citations
Publications
Featured Publications
Toward a Clearer Definition of Selection Bias When Estimating Causal Effects
Lu H, Cole S, Howe C, Westreich D. Toward a Clearer Definition of Selection Bias When Estimating Causal Effects. Epidemiology 2022, 33: 699-706. PMID: 35700187, PMCID: PMC9378569, DOI: 10.1097/ede.0000000000001516.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsRevisiting Overadjustment Bias
Lu H, Cole S, Platt R, Schisterman E. Revisiting Overadjustment Bias. Epidemiology 2021, 32: e22-e23. PMID: 34172691, DOI: 10.1097/ede.0000000000001377.Peer-Reviewed Original ResearchCitationsAltmetricClinical Effectiveness of Integrase Strand Transfer Inhibitor–Based Antiretroviral Regimens Among Adults With Human Immunodeficiency Virus: A Collaboration of Cohort Studies in the United States and Canada
Lu H, Cole S, Westreich D, Hudgens M, Adimora A, Althoff K, Silverberg M, Buchacz K, Li J, Edwards J, Rebeiro P, Lima V, Marconi V, Sterling T, Horberg M, Gill M, Kitahata M, Eron J, Moore R. Clinical Effectiveness of Integrase Strand Transfer Inhibitor–Based Antiretroviral Regimens Among Adults With Human Immunodeficiency Virus: A Collaboration of Cohort Studies in the United States and Canada. Clinical Infectious Diseases 2020, 73: e1408-e1414. PMID: 32780095, PMCID: PMC8492356, DOI: 10.1093/cid/ciaa1037.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsIntegrase strand transfer inhibitorsHuman immunodeficiency virusHazard ratioEFV groupAntiretroviral therapyStrand transfer inhibitorsClinical outcomesRisk differenceINSTI groupComposite outcomeImmunodeficiency virusClinical effectivenessNorth American AIDS Cohort CollaborationFirst-line antiretroviral therapyEnd-stage liver diseaseLong-term clinical effectivenessEnd-stage renal diseaseLong-term clinical outcomesComposite clinical outcomeFirst ART regimenInitial ART regimensAdverse clinical outcomesModern antiretroviral therapyTransfer inhibitorsAcute myocardial infarctionFour targets: an enhanced framework for guiding causal inference from observational data
Lu H, Li F, Lesko C, Fink D, Rudolph K, Harhay M, Rentsch C, Fiellin D, Gonsalves G. Four targets: an enhanced framework for guiding causal inference from observational data. International Journal Of Epidemiology 2024, 54: dyaf003. PMID: 39868475, PMCID: PMC11769716, DOI: 10.1093/ije/dyaf003.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsSelection Bias Requires Selection: The Case of Collider Stratification Bias
Lu H, Gonsalves G, Westreich D. Selection Bias Requires Selection: The Case of Collider Stratification Bias. American Journal Of Epidemiology 2023, 193: 407-409. PMID: 37939152, PMCID: PMC10911840, DOI: 10.1093/aje/kwad213.Peer-Reviewed Original ResearchCitationsAltmetricGeographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019
Lu H, Crawford F, Gonsalves G, Grau L. Geographic and temporal trends in fentanyl-detected deaths in Connecticut, 2009–2019. Annals Of Epidemiology 2023, 79: 32-38. PMID: 36669599, PMCID: PMC10163838, DOI: 10.1016/j.annepidem.2023.01.009.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and Concepts
2025
Longitudinal patterns of attention-deficit/hyperactivity disorder children in Shanghai, China.
Qiu X, Zhu D, Fu X, Huo Y, Chen X, Zhang J, Wang S, Aisikeer A, Hong X, Lu H, Tang W, Chen J. Longitudinal patterns of attention-deficit/hyperactivity disorder children in Shanghai, China. Sci Rep 2025, 15: 20305. PMID: 40571692, DOI: 10.1038/s41598-025-02254-x.Peer-Reviewed Original ResearchRevisiting representativeness.
Lu H, Zivich PN, Rudolph JE, Liew Z, Mukherjee B, Li F. Revisiting representativeness. Int J Epidemiol 2025, 54 PMID: 40587415, DOI: 10.1093/ije/dyaf109.Peer-Reviewed Original ResearchAuthor Correction: Pay-it-forward incentives for hepatitis virus testing in men who have sex with men: a cluster randomized trial
Zhang Y, Li J, Xie Y, Wu D, Ong J, Marley G, Kamarulzaman A, Lu H, Zou F, Smith J, Tucker J, Fu G, Tang W. Author Correction: Pay-it-forward incentives for hepatitis virus testing in men who have sex with men: a cluster randomized trial. Nature Medicine 2025, 1-1. PMID: 40205200, DOI: 10.1038/s41591-025-03690-y.Peer-Reviewed Original ResearchAltmetricFrequency and Intensity of Depressive Symptoms and Frequency of Prescribed Opioid Use Among Older Adults in the United States: Results of a National Survey.
Zhu X, Ge S, Ma W, Wu L, Ma H, Hu J, Lu H, Lin X. Frequency and Intensity of Depressive Symptoms and Frequency of Prescribed Opioid Use Among Older Adults in the United States: Results of a National Survey. J Addict Nurs 2025 PMID: 39919217, DOI: 10.1097/JAN.0000000000000604.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
Activities
activity Epidemiologic Methods
2024 - PresentJournal ServiceAssociate Editoractivity Design and Analysis Group (DAG)
2024 - PresentAdvisory BoardsCo-ChairDetailsThe Veterans Aging Cohort Study (VACS)activity Yale Pharmacoepidemiology Workgroup
2024 - PresentAdvisory BoardsCo-FounderDetailsYale Universityactivity AJE Advances: Research in Epidemiology
2024 - PresentJournal ServiceAssociate Editoractivity The Journal of Addiction Medicine
2025 - PresentJournal ServiceStatistical Editor
Honors
honor K99/R00 Pathway to Independence Award
02/01/2023National AwardNIH/NIDADetailsUnited Stateshonor The Lilienfeld Postdoctoral Prize Paper Award Finalist
01/01/2023International AwardThe Society for Epidemiologic ResearchDetailsUnited Stateshonor ViiV Healthcare Fellowship
06/01/2019Regional AwardUNC Gillings School of Global Public HealthDetailsUnited Stateshonor The Miriam E. Brailey Fund
04/01/2016Regional AwardJohns Hopkins Bloomberg School of Public HealthDetailsUnited States
Get In Touch
Contacts
Email
Locations
E.S. Harkness Memorial Hall
Academic Office
367 Cedar Street
New Haven, CT 06510