Sheng-Nan Qiao, PhD
Associate Research Scientist in GeneticsCards
About
Research
Publications
2019
ON-Type Retinal Ganglion Cells are Preferentially Affected in STZ-Induced Diabetic Mice.
Cui RZ, Wang L, Qiao SN, Wang YC, Wang X, Yuan F, Weng SJ, Yang XL, Zhong YM. ON-Type Retinal Ganglion Cells are Preferentially Affected in STZ-Induced Diabetic Mice. Investigative Ophthalmology & Visual Science 2019, 60: 1644-1656. PMID: 30995300, DOI: 10.1167/iovs.18-26359.Peer-Reviewed Original Research
2017
Orexin-A Suppresses Signal Transmission to Dopaminergic Amacrine Cells From Outer and Inner Retinal Photoreceptors
Qiao SN, Zhou W, Liu LL, Zhang DQ, Zhong YM. Orexin-A Suppresses Signal Transmission to Dopaminergic Amacrine Cells From Outer and Inner Retinal Photoreceptors. Investigative Ophthalmology & Visual Science 2017, 58: 4712-4721. PMID: 28910447, PMCID: PMC5598320, DOI: 10.1167/iovs.17-21835.Peer-Reviewed Original ResearchConceptsDopaminergic amacrine cellsInner retinal photoreceptorsOrexin receptorsAmacrine cellsVisual functionRetinal photoreceptorsWhole-cell voltage-clamp techniqueOuter retinal photoreceptorsVoltage-clamp techniqueNeuropeptide orexinEndogenous orexinsDopaminergic systemUpstream neuronsOrexinCone functionMammalian retinaMouse retinaGenetic deletionRetinaVertebrate retinaIpRGCsReceptorsLight-induced responsesPhotoreceptorsResponse
2016
Multiple cone pathways are involved in photic regulation of retinal dopamine
Qiao SN, Zhang Z, Ribelayga CP, Zhong YM, Zhang DQ. Multiple cone pathways are involved in photic regulation of retinal dopamine. Scientific Reports 2016, 6: 28916. PMID: 27356880, PMCID: PMC4928117, DOI: 10.1038/srep28916.Peer-Reviewed Original ResearchConceptsDopaminergic amacrine cellsRetinal dopamineAmacrine cellsBipolar cellsPhotosensitive retinal ganglion cellsCone-mediated responsesOFF bipolar cellsRetinal ganglion cellsParallel excitatoryInhibitory circuitsGanglion cellsExcitatory inputsDopamine releaseInhibitory responsesCone functionKey neurotransmitterNeural pathwaysCone pathwaysType 1Dye injectionDopamineRetinaPhotic regulationCellsDAC activity