Lauren Hachmann Sansing
Research & Publications
Biography
News
Research Summary
The Sansing lab studies the responses of the immune system after stroke, intracerebral hemorrhage, vascular dementia, and aging. Once injury occurs, microglia, the resident immune cells of the brain, become activated. In addition, blood leukocytes, including neutrophils, macrophages, and T cells, enter into the brain. Each cell contributes to brain injury and recovery in different ways. Our work aims to discover which responses harm the brain and should be inhibited, and which responses contribute to recovery and should be augmented. The overall goal of our research is to identify new therapeutic targets that modulate immune responses in the brain to maximize recovery.
Coauthors
Research Interests
Cerebral Hemorrhage; Inflammation; Dementia, Vascular; Stroke; Translational Research, Biomedical
Selected Publications
- Abstract 15: Single-cell Immune Landscape Of Human Clot Retrieved At Mechanical Thrombectomy. Association With Stroke Origin.Renedo D, Sujijantarat N, Antonios J, Koo A, Acosta J, Falcone G, Hebert R, Sansing L, Navaratnam D, Matouk C. Abstract 15: Single-cell Immune Landscape Of Human Clot Retrieved At Mechanical Thrombectomy. Association With Stroke Origin. Stroke 2023, 54: a15-a15. DOI: 10.1161/str.54.suppl_1.15.
- Abstract 9: Autoregulation-based Blood Pressure Targets After Endovascular ThrombectomyPetersen N, Begunova Y, Olexa M, Bartolome D, Kumar A, Chen Y, Dhar R, Peng T, Ortega-Gutierrez S, Falcone G, gilmore E, Kim J, Schindler J, Sansing L, Matouk C, Sheth K. Abstract 9: Autoregulation-based Blood Pressure Targets After Endovascular Thrombectomy Stroke 2023, 54: a9-a9. DOI: 10.1161/str.54.suppl_1.9.
- Abstract TMP79: Deep Learning Model For Prediction Of Supratentorial Intracerebral Hemorrhage (ich) ExpansionTran A, Zeevi T, Berson E, Tharmaseelan H, Haider S, Qureshi A, Sansing L, Falcone G, Sheth K, Payabvash S. Abstract TMP79: Deep Learning Model For Prediction Of Supratentorial Intracerebral Hemorrhage (ich) Expansion Stroke 2023, 54: atmp79-atmp79. DOI: 10.1161/str.54.suppl_1.tmp79.
- Abstract TMP80: Sex Is Associated With Location, Severity And Outcome Of Intracerebral Hemorrhage: A Combined Analysis Of Four Landmark StudiesRivier C, Acosta J, Renedo D, Marini S, Magid-Bernstein J, Rosand J, Hanley D, Ziai W, Mayer S, Woo D, Sansing L, Sheth K, Anderson C, Falcone G. Abstract TMP80: Sex Is Associated With Location, Severity And Outcome Of Intracerebral Hemorrhage: A Combined Analysis Of Four Landmark Studies Stroke 2023, 54: atmp80-atmp80. DOI: 10.1161/str.54.suppl_1.tmp80.
- Abstract TMP99: Neighborhood Disadvantage And Outcomes Following Intracerebral HemorrhageKim J, Rivier C, Renedo D, Lopez V, Schlechter M, Kitlen E, Kampp M, Jasak S, Sansing L, Sheth K, Falcone G. Abstract TMP99: Neighborhood Disadvantage And Outcomes Following Intracerebral Hemorrhage Stroke 2023, 54: atmp99-atmp99. DOI: 10.1161/str.54.suppl_1.tmp99.
- Abstract TP115: Racial/ethnic Differences In Subacute Blood Pressure Trajectories Following Intracerebral HemorrhageTorres-Lopez V, Hawkes M, Rivier C, Kim J, Kitlen E, Schlechter M, Kampp M, Jasak S, Petersen N, Kim J, De Havenon A, Sansing L, Sheth K, Falcone G. Abstract TP115: Racial/ethnic Differences In Subacute Blood Pressure Trajectories Following Intracerebral Hemorrhage Stroke 2023, 54: atp115-atp115. DOI: 10.1161/str.54.suppl_1.tp115.
- Abstract WP154: Low-field Portable Mri For Routine Post-thrombectomy Assessment Of Ongoing Brain InjurySujijantarat N, Koo A, Jambor I, Malhotra A, Crawford A, Mazurek M, Parasuram N, Yadlapalli V, Chavva I, Antonios J, Elsamadicy A, Renedo D, Hebert R, Schindler J, Sansing L, De Havenon A, Olexa M, Iglesias J, Rosen M, Kimberly W, Petersen N, Sheth K, Matouk C. Abstract WP154: Low-field Portable Mri For Routine Post-thrombectomy Assessment Of Ongoing Brain Injury Stroke 2023, 54: awp154-awp154. DOI: 10.1161/str.54.suppl_1.wp154.
- Abstract TP216: Suppression Of Macrophage Activation By MyelinDeLong J, Sun L, Velazquez S, Landreneau M, Sansing L. Abstract TP216: Suppression Of Macrophage Activation By Myelin Stroke 2023, 54: atp216-atp216. DOI: 10.1161/str.54.suppl_1.tp216.
- Polygenic Susceptibility to Hypertension and Blood Pressure Control in Stroke SurvivorsAcosta J, Both C, Demarais Z, Conlon C, Leasure A, Torres-Lopez V, de Havenon A, Petersen N, Gill T, Sansing L, Sheth K, Falcone G. Polygenic Susceptibility to Hypertension and Blood Pressure Control in Stroke Survivors Neurology 2023, 100: e1587-e1597. PMID: 36690452, PMCID: PMC10103110, DOI: 10.1212/wnl.0000000000206763.
- Role of Inflammatory Processes in Hemorrhagic StrokeOhashi S, DeLong J, Kozberg M, Mazur-Hart D, van Veluw S, Alkayed N, Sansing L. Role of Inflammatory Processes in Hemorrhagic Stroke Stroke 2023, 54: 605-619. PMID: 36601948, DOI: 10.1161/strokeaha.122.037155.
- Embracing Heterogeneity in The Multicenter Stroke Preclinical Assessment Network (SPAN) TrialMorais A, Locascio J, Sansing L, Lamb J, Nagarkatti K, Imai T, van Leyen K, Aronowski J, Koenig J, Bosetti F, Lyden P, Ayata C, Bosetti F, Koenig J, Lyden P, Lamb J, Nagarkatti K, Hess D, Kamat P, Khan M, Dhandapani K, Arbab A, Siddiqui S, Smith C, Nisar M, Leira E, Chauhan A, Dhanesha N, Patel R, Kumskova M, Thedens D, Wang K, Ayata C, Morais A, Imai T, Qin T, Jin X, Erdogan T, Yu L, Mandeville J, Kimberly W, Whittier J, Lo E, Arai K, Van Leyen K, Sansing L, Hyder F, Mihailovic J, Sanganahalli B, Diaz-Perez S, Velazquez S, Beatty H, Johnson C, Herman A, Boisserand L, Immakavar E, Koehler R, Dawson T, Dawson V, Shi Y, Avery B, Lannon S, Bibic A, Akhter K, Karuppagounder S, Aronowski J, McCullough L, Obertas L, Goh A, Huang S, Chauhan A. Embracing Heterogeneity in The Multicenter Stroke Preclinical Assessment Network (SPAN) Trial Stroke 2023, 54: 620-631. PMID: 36601951, PMCID: PMC9870939, DOI: 10.1161/strokeaha.122.040638.
- Association of Soluble ST2 With Functional Outcome, Perihematomal Edema, and Immune Response After Intraparenchymal HemorrhageBevers M, Booraem C, Li K, Sreekrishnan A, Sastre C, Falcone G, Sheth K, Sansing L, Kimberly W. Association of Soluble ST2 With Functional Outcome, Perihematomal Edema, and Immune Response After Intraparenchymal Hemorrhage Neurology 2022, 100: e1329-e1338. PMID: 36549913, PMCID: PMC10065211, DOI: 10.1212/wnl.0000000000206764.
- Technical Dissonance in Home Blood Pressure Monitoring After Stroke: Having the Machine, but Not Using Correctly.Forman R, Viscoli C, Meurer K, Sheth K, Sansing L, de Havenon A, Sharma R, Mariscal M, Kernan W. Technical Dissonance in Home Blood Pressure Monitoring After Stroke: Having the Machine, but Not Using Correctly. American Journal Of Hypertension 2022, 36: 195-200. PMID: 36520024, PMCID: PMC10016067, DOI: 10.1093/ajh/hpac129.
- Baseline Serum Biomarkers of Inflammation and Subsequent Visit-to-Visit Blood Pressure Variability: A Post Hoc Analysis of MESA.Wong KH, Muddasani V, Peterson C, Sheibani N, Arkin C, Cheong I, Majersik JJ, Biffi A, Petersen N, Falcone GJ, Sansing LH, de Havenon AH. Baseline Serum Biomarkers of Inflammation and Subsequent Visit-to-Visit Blood Pressure Variability: A Post Hoc Analysis of MESA. American Journal Of Hypertension 2022, 36: 144-147. PMID: 36315490, DOI: 10.1093/ajh/hpac122.
- Neuroimmune interactions in health and diseaseHafler DA, Sansing LH. Neuroimmune interactions in health and disease Seminars In Immunopathology 2022, 44: 565-567. PMID: 36171280, DOI: 10.1007/s00281-022-00963-3.
- Association of Chronic Kidney Disease With Risk of Intracerebral HemorrhageVanent KN, Leasure AC, Acosta JN, Kuohn LR, Woo D, Murthy SB, Kamel H, Messé SR, Mullen MT, Cohen JB, Cohen DL, Townsend RR, Petersen NH, Sansing LH, Gill TM, Sheth KN, Falcone GJ. Association of Chronic Kidney Disease With Risk of Intracerebral Hemorrhage JAMA Neurology 2022, 79: 911-918. PMID: 35969388, PMCID: PMC9379821, DOI: 10.1001/jamaneurol.2022.2299.
- Dataset on acute stroke risk stratification from CT angiographic radiomicsAvery EW, Behland J, Mak A, Haider SP, Zeevi T, Sanelli PC, Filippi CG, Malhotra A, Matouk CC, Griessenauer CJ, Zand R, Hendrix P, Abedi V, Falcone GJ, Petersen N, Sansing LH, Sheth KN, Payabvash S. Dataset on acute stroke risk stratification from CT angiographic radiomics Data In Brief 2022, 44: 108542. PMID: 36060820, PMCID: PMC9428796, DOI: 10.1016/j.dib.2022.108542.
- Inflammatory Responses After Ischemic StrokeDeLong JH, Ohashi SN, O’Connor K, Sansing LH. Inflammatory Responses After Ischemic Stroke Seminars In Immunopathology 2022, 44: 625-648. PMID: 35767089, DOI: 10.1007/s00281-022-00943-7.
- Genetically‐Proxied Levels of Vitamin D and Risk of Intracerebral HemorrhageSzejko N, Acosta JN, Both CP, Leasure A, Matouk C, Sansing L, Gill TM, Hongyu Z, Sheth K, Falcone GJ. Genetically‐Proxied Levels of Vitamin D and Risk of Intracerebral Hemorrhage Journal Of The American Heart Association 2022, 11: e024141. PMID: 35730641, PMCID: PMC9333362, DOI: 10.1161/jaha.121.024141.
- 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke AssociationGreenberg SM, Ziai WC, Cordonnier C, Dowlatshahi D, Francis B, Goldstein JN, Hemphill JC, Johnson R, Keigher KM, Mack WJ, Mocco J, Newton EJ, Ruff IM, Sansing LH, Schulman S, Selim MH, Sheth KN, Sprigg N, Sunnerhagen KS, Association O. 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association Stroke 2022, 53: e282-e361. PMID: 35579034, DOI: 10.1161/str.0000000000000407.
- CT angiographic radiomics signature for risk stratification in anterior large vessel occlusion strokeAvery EW, Behland J, Mak A, Haider SP, Zeevi T, Sanelli PC, Filippi CG, Malhotra A, Matouk CC, Griessenauer CJ, Zand R, Hendrix P, Abedi V, Falcone GJ, Petersen N, Sansing LH, Sheth KN, Payabvash S. CT angiographic radiomics signature for risk stratification in anterior large vessel occlusion stroke NeuroImage Clinical 2022, 34: 103034. PMID: 35550243, PMCID: PMC9108990, DOI: 10.1016/j.nicl.2022.103034.
- Portable, low-field magnetic resonance imaging enables highly accessible and dynamic bedside evaluation of ischemic strokeYuen MM, Prabhat AM, Mazurek MH, Chavva IR, Crawford A, Cahn BA, Beekman R, Kim JA, Gobeske KT, Petersen NH, Falcone GJ, Gilmore EJ, Hwang DY, Jasne AS, Amin H, Sharma R, Matouk C, Ward A, Schindler J, Sansing L, de Havenon A, Aydin A, Wira C, Sze G, Rosen MS, Kimberly WT, Sheth KN. Portable, low-field magnetic resonance imaging enables highly accessible and dynamic bedside evaluation of ischemic stroke Science Advances 2022, 8: eabm3952. PMID: 35442729, PMCID: PMC9020661, DOI: 10.1126/sciadv.abm3952.
- Cerebral Hemorrhage: Pathophysiology, Treatment, and Future DirectionsMagid-Bernstein J, Girard R, Polster S, Srinath A, Romanos S, Awad IA, Sansing LH. Cerebral Hemorrhage: Pathophysiology, Treatment, and Future Directions Circulation Research 2022, 130: 1204-1229. PMID: 35420918, PMCID: PMC10032582, DOI: 10.1161/circresaha.121.319949.
- The Stroke Preclinical Assessment Network: Rationale, Design, Feasibility, and Stage 1 ResultsLyden PD, Bosetti F, Diniz MA, Rogatko A, Koenig JI, Lamb J, Nagarkatti KA, Cabeen RP, Hess DC, Kamat PK, Khan MB, Wood K, Dhandapani K, Arbab AS, Leira EC, Chauhan AK, Dhanesha N, Patel RB, Kumskova M, Thedens D, Morais A, Imai T, Qin T, Ayata C, Boisserand LSB, Herman AL, Beatty HE, Velazquez SE, Diaz-Perez S, Sanganahalli BG, Mihailovic JM, Hyder F, Sansing LH, Koehler RC, Lannon S, Shi Y, Karuppagounder SS, Bibic A, Akhter K, Aronowski J, McCullough LD, Chauhan A, Goh A, Siddiqui S, Sheth K, Matouk C, Cruz C, Zhou J, Dawson V, Dawson T, Liang J, van Zijl P, Zeiler S, Taylor Kimberly W, Erdogan T, Yu L, Mandeville J, Whittier J. The Stroke Preclinical Assessment Network: Rationale, Design, Feasibility, and Stage 1 Results Stroke 2022, 53: 1802-1812. PMID: 35354299, PMCID: PMC9038686, DOI: 10.1161/strokeaha.121.038047.
- Maximizing Brain Health After Hemorrhagic Stroke: Bugher Foundation Centers of ExcellenceSheth KN, Anderson CD, Biffi A, Dlamini N, Falcone GJ, Fox CK, Fullerton HJ, Greenberg SM, Hemphill JC, Kim A, Kim H, Ko NU, Roland JL, Sansing LH, van Veluw SJ, Rosand J. Maximizing Brain Health After Hemorrhagic Stroke: Bugher Foundation Centers of Excellence Stroke 2022, 53: 1020-1029. PMID: 35109678, PMCID: PMC8885885, DOI: 10.1161/strokeaha.121.036197.
- Abstract TP134: Association Of Neutrophil-lymphocyte Ratio With Functional Outcome In Spontaneous Intracerebral HemorrhageAtillasoy J, Leasure A, Schwartz A, Reznik M, Moody S, Bevers M, Matouk C, Falcone G, Sansing L, Kimberly W, Sheth K. Abstract TP134: Association Of Neutrophil-lymphocyte Ratio With Functional Outcome In Spontaneous Intracerebral Hemorrhage Stroke 2022, 53: atp134-atp134. DOI: 10.1161/str.53.suppl_1.tp134.
- Abstract TMP112: Stroke-associated Pneumonia Impairs Pulmonary Host Defense While Infection Impairs Stroke RecoveryBoisserand L, Sharma L, Tran T, Chen B, Kim J, Dela Cruz C, Sansing L. Abstract TMP112: Stroke-associated Pneumonia Impairs Pulmonary Host Defense While Infection Impairs Stroke Recovery Stroke 2022, 53: atmp112-atmp112. DOI: 10.1161/str.53.suppl_1.tmp112.
- Abstract WP111: Deployment Of Portable, Bedside, Low-field Magnetic Resonance Imaging In The Emergency Department To Evaluate Patients With Acute StrokeChavva I, Mazurek M, Yuen M, Prabhat A, Crawford A, Cahn B, Schindler J, Sansing L, Matouk C, Hebert R, de Havenon A, Sharma R, Payabvash S, Sze G, Aydin A, Parwani V, Ulrich A, Brown K, Sheth K, Wira C. Abstract WP111: Deployment Of Portable, Bedside, Low-field Magnetic Resonance Imaging In The Emergency Department To Evaluate Patients With Acute Stroke Stroke 2022, 53: awp111-awp111. DOI: 10.1161/str.53.suppl_1.wp111.
- Abstract TMP55: Post-stroke Blood Pressure Variability In The Acute Phase Is Associated With Pre-stroke Blood Pressure Variability In Patients Undergoing Mechanical ThrombectomySoto A, Prasad A, Kobsa J, Bartolome D, Begunova Y, Kodali S, Quispe-Orozco D, Farooqui M, Zevallos C, Sansing L, Schindler J, Matouk C, Sheth K, de Havenon A, Ortega-Gutierrez S, Petersen N. Abstract TMP55: Post-stroke Blood Pressure Variability In The Acute Phase Is Associated With Pre-stroke Blood Pressure Variability In Patients Undergoing Mechanical Thrombectomy Stroke 2022, 53: atmp55-atmp55. DOI: 10.1161/str.53.suppl_1.tmp55.
- Abstract 91: Large Vessel Occlusion Stroke Patients With Rapid Early Infarct Progression And Poor Collaterals Are Vulnerable To Blood Pressure ReductionsBegunova Y, Bartolome D, Kobsa J, Prasad A, Soto A, Quispe-Orozco D, Farooqui M, Zevallos C, Sansing L, Schindler J, De Havenon A, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Abstract 91: Large Vessel Occlusion Stroke Patients With Rapid Early Infarct Progression And Poor Collaterals Are Vulnerable To Blood Pressure Reductions Stroke 2022, 53: a91-a91. DOI: 10.1161/str.53.suppl_1.91.
- Abstract TP222: The Impact Of Il-6 Level On Visit-to-visit Blood Pressure Variability And Incidence Of Stroke: A Post-hoc Analysis Of MesaWong K, Muddasani V, Peterson C, Sheibani N, Arkin C, Cheong I, Majersik J, Sansing L, de Havenon A. Abstract TP222: The Impact Of Il-6 Level On Visit-to-visit Blood Pressure Variability And Incidence Of Stroke: A Post-hoc Analysis Of Mesa Stroke 2022, 53: atp222-atp222. DOI: 10.1161/str.53.suppl_1.tp222.
- Abstract WP76: Patients Express Satisfaction With Acute Video Telestroke ConsultationsPeng T, Vlieks K, Parker R, Nystrom K, Salas S, Schindler J, Sansing L, Sharma R, Forman R, Petersen N, Jasne A, Narula R, Amin H. Abstract WP76: Patients Express Satisfaction With Acute Video Telestroke Consultations Stroke 2022, 53: awp76-awp76. DOI: 10.1161/str.53.suppl_1.wp76.
- Abstract WMP59: Trends And Predictors Of Delay In Hospital Presentation After Symptom Onset Among Ischemic Stroke Patients: A Single-center StudyOkumu R, Baker A, Wira C, Schindler J, Sansing L, Jasne A, Amin H, Narula R, Forman R, Sharma R. Abstract WMP59: Trends And Predictors Of Delay In Hospital Presentation After Symptom Onset Among Ischemic Stroke Patients: A Single-center Study Stroke 2022, 53: awmp59-awmp59. DOI: 10.1161/str.53.suppl_1.wmp59.
- Abstract WP74: An Automated, Electronic Health Record-based Algorithm To Classify Ischemic Stroke EtiologySharma R, Lee H, Schwamm L, Kamel H, Sansing L, Kim J, Zhao H, Krumholz H, Sharma R. Abstract WP74: An Automated, Electronic Health Record-based Algorithm To Classify Ischemic Stroke Etiology Stroke 2022, 53: awp74-awp74. DOI: 10.1161/str.53.suppl_1.wp74.
- Abstract 99: Single Cell RNA-Sequencing Reveals Array Of Immune Activation States In Intracerebral HemorrhageJohnson C, Askenase M, Beatty H, DeLong J, Zhang L, Sheth K, Cord B, Hebert R, Matouk C, Sansing L. Abstract 99: Single Cell RNA-Sequencing Reveals Array Of Immune Activation States In Intracerebral Hemorrhage Stroke 2022, 53: a99-a99. DOI: 10.1161/str.53.suppl_1.99.
- Abstract TP239: Cholesterol And LXR Signaling In The Macrophage Response To Intracerebral Hemorrhage-relevant StimulationDelong J, Velazquez S, Sun L, Landreneau M, Sansing L. Abstract TP239: Cholesterol And LXR Signaling In The Macrophage Response To Intracerebral Hemorrhage-relevant Stimulation Stroke 2022, 53: atp239-atp239. DOI: 10.1161/str.53.suppl_1.tp239.
- Acute Ischemic Stroke, Depressed Left Ventricular Ejection Fraction, and Sinus Rhythm: Prevalence and Practice PatternsBaker AD, Schwamm LH, Sanborn DY, Furie K, Stretz C, Grory B, Yaghi S, Kleindorfer D, Sucharew H, Mackey J, Walsh K, Flaherty M, Kissela B, Alwell K, Khoury J, Khatri P, Adeoye O, Ferioli S, Woo D, Martini S, La Rosa F, Demel SL, Madsen T, Star M, Coleman E, Slavin S, Jasne A, Mistry EA, Haverbusch M, Merkler AE, Kamel H, Schindler J, Sansing LH, Faridi KF, Sugeng L, Sheth KN, Sharma R. Acute Ischemic Stroke, Depressed Left Ventricular Ejection Fraction, and Sinus Rhythm: Prevalence and Practice Patterns Stroke 2022, 53: 1883-1891. PMID: 35086361, PMCID: PMC10214981, DOI: 10.1161/strokeaha.121.036706.
- Bedside detection of intracranial midline shift using portable magnetic resonance imagingSheth KN, Yuen MM, Mazurek MH, Cahn BA, Prabhat AM, Salehi S, Shah JT, By S, Welch EB, Sofka M, Sacolick LI, Kim JA, Payabvash S, Falcone GJ, Gilmore EJ, Hwang DY, Matouk C, Gordon-Kundu B, RN AW, Petersen N, Schindler J, Gobeske KT, Sansing LH, Sze G, Rosen MS, Kimberly WT, Kundu P. Bedside detection of intracranial midline shift using portable magnetic resonance imaging Scientific Reports 2022, 12: 67. PMID: 34996970, PMCID: PMC8742125, DOI: 10.1038/s41598-021-03892-7.
- 8 Mechanisms of Damage After Cerebral HemorrhageAronowski J, Sansing L, Xi G, Zhang J. 8 Mechanisms of Damage After Cerebral Hemorrhage 2022, 92-102.e9. DOI: 10.1016/b978-0-323-69424-7.00008-9.
- International Post Stroke Epilepsy Research Consortium (IPSERC): A consortium to accelerate discoveries in preventing epileptogenesis after strokeMishra NK, Engel J, Liebeskind DS, Sharma VK, Hirsch LJ, Kasner SE, French JA, Devinsky O, Friedman A, Dawson J, Quinn TJ, Selim M, de Havenon A, Yasuda CL, Cendes F, Benninger F, Zaveri HP, Burneo JG, Srivastava P, Singh M, Bhatia R, Vishnu VY, Bentes C, Ferro J, Weiss S, Sivaraju A, Kim JA, Galovic M, Gilmore EJ, Pitkänen A, Davis K, Sansing LH, Sheth KN, Paz JT, Singh A, Sheth S, Worrall BB, Grotta JC, Casillas-Espinos PM, Chen Z, Nicolo JP, Yan B, Kwan P, Consortium F. International Post Stroke Epilepsy Research Consortium (IPSERC): A consortium to accelerate discoveries in preventing epileptogenesis after stroke Epilepsy & Behavior 2021, 127: 108502. PMID: 34968775, DOI: 10.1016/j.yebeh.2021.108502.
- Assessment of Discrepancies Between Follow-up Infarct Volume and 90-Day Outcomes Among Patients With Ischemic Stroke Who Received Endovascular TherapyGanesh A, Ospel J, Menon B, Demchuk A, McTaggart R, Nogueira R, Poppe A, Almekhlafi M, Hanel R, Thomalla G, Holmin S, Puetz V, van Adel B, Tarpley J, Tymianski M, Hill M, Goyal M, Barber P, Smith E, Bal S, Subramanian S, Peters S, Couillard P, Klein G, Stys P, Coutts S, Wong J, Mitha A, Eesa M, Morrish W, Alqatani S, Kashani N, Venkatesan P, Teleg E, Sitaram A, Graham B, Gaal S, Moussaddy A, Chakraborty D, Maraj N, Lockey A, Chen S, Singh R, Alsultan A, Asunsian R, Tse D, Doshi D, Volny O, Ojha P, Wadhwa A, Marko M, Singh N, Wasyliw S, Ryckborst K, Kenney C, Save S, Jambula A, Newcommon N, Hull G, Blackstock D, Kiszczak S, Zimmel L, Wright M, Jahraus C, Andersen L, Bohn S, Paul J, Buck B, Butcher K, Shuaib A, Jeerakathil T, Jickling G, Emery D, Rempel J, Ower R, Ashforth R, Yeo T, Kotylak T, O;Kelly C, Chow M, Siddiqui M, Saqqur M, D'Souza A, Lloret M, Butt A, Nomani A, Kalashyan H, Thirunavukkarasu S, Jabs J, Fairall P, Piquette L, Phillips S, Green A, Gubitz G, Heidenreich J, Huynh T, Shankar J, Maloney W, Vandorpe R, Schmidt M, Pickett G, Weeks A, Jarrett J, MacDonald D, Arsenault J, Kinnear R, Mandzia J, Mayich M, Boulton M, Bullrich M, Fridman S, Kiwan R, Lee D, Lownie S, Khaw A, Pandey S, Sharma M, Sposato L, Wade K, Beauchamp B, Lambourn L, Amato-Marziali B, Roy D, Deneault N, Deschaintre Y, Gioia L, Jacquin G, Odier C, Stapf C, Iancu D, Raymond J, Weill A, Lapierre M, Jadil N, Jolteus J, Teitelbaum J, Angle M, Hannouche M, Badawy M, Letourneau J, Cortes M, Linnell G, Tampieri D, Vieira L, Legault C, Durcan L, Moore A, Cole E, Magnussen C, Salmon K, Khalil S, Desloges I, Waxman L, Abdon W, Lai S, Dowlatshahi D, Shamy M, Stotts G, Blacquiere D, Lesiuk H, Quateen A, Drake B, Dewar B, Daham Z, Kelly M, Hunter G, Peeling L, Graham B, Whelan R, Garner A, Urroz L, Maley S, Silver F, Casaubon L, Pikula A, Campo M, Schaafsma J, Jaigobin C, Krings T, Pereira V, Agid R, Farb R, Kalman L, Cayley A, Williams J, Stewart T, Misquitta K, Bharatha A, Selchen D, Marotta T, Sarma D, Montanera W, Spears J, Saposnik G, Kostyrko P, Li Y, Parra-Farinas C, Diestro J, Camden M, Verreault S, Mackey A, Audet M, Milot G, Lavoie P, Gariépy J, Collard K, Haché A, Sahlas D, Alshanbari A, Baldwin J, Catanese L, Chen B, Sa Boasquevisque D, Deshmukh A, Knapman J, Lamers S, Larrazabal R, MacMillan S, Mai L, Mattai A, Nayar S, Ng K, Oczkowski W, Perera K, Shawawrah M, Shoamanesh A, Sobhi G, Syed N, Yaher N, Vandervelde C, Wang D, Field T, Van Gaal S, Teal P, Benavente O, Wilson L, Mann S, Yip S, Murphy C, Heran M, Rohr A, Settecase F, Redekop G, Haw C, Maclean G, Murray K, Chiu R, Flexman A, Strecha E, Gayton Y, Yip J, Swartz R, Boulos M, Gladstone D, Yu A, Hopyan J, Khosravani H, Manosalva Alzate H, Southwell A, Kamra M, Lopes K, Kapoor A, da Costa L, Yang V, Dyer E, Shah R, Knowles B, Nichols J, Patterson J, Cope K, Dickerson L, Barton K, Gray K, Massengale T, Miller M, Simpson C, Walker S, Tennyson-Yemm C, Frei D, Bellon R, Atchie B, Kaminsky I, Wilson D, Schraeder N, Arias E, Kodis L, Talley M, Edinger A, Talley T, Dempsey I, Williams L, Williams S, Kupniewski S, Fasbinder B, Snead J, Choe H, Mackenzie L, Weisman D, Kozak O, Shah Q, Gzesh D, Kulandaivel K, Khoury J, Klein B, Bussinger P, Griffin L, DePalmo A, Oliva C, Jadhav A, Jovin T, Kenmuir C, Jankowitz B, Gross B, Rocha M, Starr M, Brown M, Hawkes C, Shah K, Tememe D, Walker G, Patel P, Klein B, Ziayee H, Limaye K, Baxendell L, Glichrist V, Feineigle P, Toseki Haibach K, Van Every C, Desai S, Zulfiqar M, Gibson L, Barrett S, Turkel-Parrella D, Arcot K, DiCrescento S, Farkas J, Filipowski G, Frontera J, Joset D, Liff J, Scher E, McDougall C, Kelly C, Patel A, Monteith S, Starkman S, Atchaneeyasakul K, Burgos A, Anne Y. Chua J, Gaines N, Grunberg I, Guzy J, Liu Z, Maluste N, Ramirez L, Sharma L, Heck D, Brown M, McDonald C, Calderon M, Hargis M, Roels C, Emmady P, Alvi T, Jayaraman M, Cutting S, Smith W, Foley S, Paolucci G, Haas R, Quinn K, Fuller L, Brierley R, Watkins C, Demir N, Lopez G, Vargas A, Osteraas N, Holtz B, Sauvageau E, Aghaebrahim A, Chmayssani M, Naval N, Day J, Dellorso S, Ludwig B, Schemmel D, Ebreo N, Bell K, Lewis L, Delucia M, Haussen D, Frankel M, Bhatt N, Bianchi N, Anderson A, Belagaje S, Liberato B, Rangaraju S, Al-Bayati A, Grossber J, Craft L, Schindler K, Schaad E, Schultz M, Sutherly L, Doppelheuer S, Charlton J, Faggard J, Barbret Z, DukSoo Han E, Walters R, Dolia J, El-Jamal S, Eby B, Saleem Y, Pearl H, Patel K, Rahman H, Butt R, English S, Puri A, Howk M, Singh J, Massari F, DeMacedo Rodrigues K, Kuhn A, English J, Barazangi N, Telischak N, Kim W, Ross J, DeVole N, Redford J, Ferreira M, Ponting K, Shen H, Bedenk A, Patel S, Fernandess J, Ke M, Spokoyny I, Gao B, Tong D, Chen C, Wong C, Choe J, Martin C, Summers D, Boutwell C, Olds K, Crandall S, Eatman J, Akhtar N, Holloway W, Halpin J, Donegan B, Schindler J, Hwang D, Gilmore E, Petersen N, Sheth K, Brown S, Beekman R, George B, Kaddouh F, Falcone G, Wira C, Matouk C, Loomis C, Amin H, Stretz H, Narula R, Jasne A, Sansing L, Agarwal T, Jasak S, Fontaine B, King Z, Kouhn L, Orgass H, Leary M, Nye J, Halbert K, Nystrom K, Neuschatz K, Petrucci D, Coppola A, Joyce T, Hou S, Umekubo M, Nakamura C, Ovando R, Zuniga D, Nien Y, Basto F, Arch A, Jong L, Conrad W, Abbott T, Yao J, Caganap S, Jordan J, Teitelbaum G, Darflinger R, Kelly D, Gupta R, Budzik R, Czerniak J, Groezinger K, Hicks W, Kaskar O, Katz B, Loochtan A, Pema P, Rai V, Vora N, Brown A, Goodman D, Danenbergs B, Gossett M, Bang O, Chung J, Jeon P, Kim K, Lim Y, Hoe Heo J, Nam H, Kim Y, Park H, Hwang I, Ha W, Choi J, Jeong K, Rha J, Park H, Yoon C, Kim B, Sohn S, Kim C, Yoo J, Hong J, Park H, Kim S, Choi M, Bae H, Lee J, Lee J, Jun G, Jeon S, Campbell B, Mitchell P, Yassi N, Davis S, Donnan G, Parsons M, Yan B, Dowling R, Bush S, Wu T, Shan D, Zhao H, Salvaris P, Alemseged F, Ng F, Williams C, Balabanski A, dos Santos A, Ng J, McDonald A, Jackson D, Tsoleridis J, Pesavento L, Kleinig T, Drew R, Cranefield J, Scroop R, Cagi L, Harvey J, Waters M, Thornton J, Brennan R, O'Hare A, Power S, Williams D, Boyle K, Moynihan B, Liddy A, Large M, Cullen A, Walsh R, Martin E, Lynch J, McElroy S, Murphy S, Coveney S, Deegan C, Horgan G, Kelly P, Laffan A, Llamas-Osorio Y, Lynch C, Mac Mahon P, Marnane M, McCabe J, Burns P, Tauro S, Cuddy S, Rennie I, Smyth G, Flynn P, Wiggam I, Kerr E, Gordon P, Fearon P, Roberts G, Patterson C, Adams K, Wells B, McFarland M, Moreira T, Sjöstrand C, Mazya M, Almqvist H, Wahlgren N, Steinberg A, Cooray C, Eriksson E, Thorén M, Keselman B, Ahmed N, Holmberg Å, Axelsson M, Berglund A, Golsari A, Hoppe J, Deb-Chatterji M, Cheng B, Barow E, Schlemm E, Lettow I, Jensen M, Otto D, Jaramillo K, Appelbohm H, Fiehler J, Bester M, Schönfeld M, Brekenfeld C, Holst B, Wortmann G, Koch F, Gerber J, Abramyuk A, Kaiser D, Winzer S, Prakapenia A, Pallesen L, Siepmann T, Barlinn K, Haase K, Sauer A, Psychogios M, Liman J, Brehm A, Maus V, Hollstein N, Reinke A, Neitz G, Schnieder M, Schwarz M, Ibrahim A, Müller J, Meister S, Bäumle B, Chapot R, Pilgram-Pastor S, Wallocha M, Stauder M, Celik E, Stracke P, Müller N, Weber R, Veltkamp R, Nagel S, Ringleb P, Heyse M, Amiri H, Mundiyanapurath S, Chen M, Beyrle E, Beck P, Möhlenbruch M. Assessment of Discrepancies Between Follow-up Infarct Volume and 90-Day Outcomes Among Patients With Ischemic Stroke Who Received Endovascular Therapy JAMA Network Open 2021, 4: e2132376. PMID: 34739060, PMCID: PMC8571657, DOI: 10.1001/jamanetworkopen.2021.32376.
- The coronal plane maximum diameter of deep intracerebral hemorrhage predicts functional outcome more accurately than hematoma volumeHaider SP, Qureshi AI, Jain A, Tharmaseelan H, Berson ER, Majidi S, Filippi CG, Mak A, Werring DJ, Acosta JN, Malhotra A, Kim JA, Sansing LH, Falcone G, Sheth K, Payabvash S. The coronal plane maximum diameter of deep intracerebral hemorrhage predicts functional outcome more accurately than hematoma volume International Journal Of Stroke 2021, 17: 777-784. PMID: 34569877, PMCID: PMC9005571, DOI: 10.1177/17474930211050749.
- Similar admission NIHSS may represent larger tissue-at-risk in patients with right-sided versus left-sided large vessel occlusionMak A, Matouk C, Avery EW, Behland J, Frey D, Madai VI, Vajkoczy P, Malhotra A, Karam A, Sanelli P, Falcone GJ, Petersen NH, Sansing L, Sheth KN, Payabvash S. Similar admission NIHSS may represent larger tissue-at-risk in patients with right-sided versus left-sided large vessel occlusion Journal Of NeuroInterventional Surgery 2021, 14: 985-991. PMID: 34645705, DOI: 10.1136/neurintsurg-2021-017785.
- Prior Stroke and Age Predict Acute Ischemic Stroke Among Hospitalized COVID-19 Patients: A Derivation and Validation StudyPeng TJ, Jasne AS, Simonov M, Abdelhakim S, Kone G, Cheng YK, Rethana M, Tarasaria K, Herman AL, Baker AD, Yaghi S, Frontera JA, Sansing LH, Falcone GJ, Spudich S, Schindler J, Sheth KN, Sharma R. Prior Stroke and Age Predict Acute Ischemic Stroke Among Hospitalized COVID-19 Patients: A Derivation and Validation Study Frontiers In Neurology 2021, 12: 741044. PMID: 34675873, PMCID: PMC8524436, DOI: 10.3389/fneur.2021.741044.
- Association of lichen planus with cardiovascular disease: A combined analysis of the UK Biobank and All of Us StudyLeasure AC, Acosta JN, Sansing LH, Sheth KN, Cohen JM, Falcone GJ. Association of lichen planus with cardiovascular disease: A combined analysis of the UK Biobank and All of Us Study Journal Of The American Academy Of Dermatology 2021, 87: 454-456. PMID: 34562549, DOI: 10.1016/j.jaad.2021.09.030.
- Exogenous inter-α inhibitor proteins prevent cell death and improve ischemic stroke outcomes in miceMcCullough LD, Roy-O’Reilly M, Lai YJ, Patrizz A, Xu Y, Lee J, Holmes A, Kraushaar DC, Chauhan A, Sansing LH, Stonestreet BS, Zhu L, Kofler J, Lim YP, Venna VR. Exogenous inter-α inhibitor proteins prevent cell death and improve ischemic stroke outcomes in mice Journal Of Clinical Investigation 2021, 131: e144898. PMID: 34580244, PMCID: PMC8409590, DOI: 10.1172/jci144898.
- Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhageMazurek MH, Cahn BA, Yuen MM, Prabhat AM, Chavva IR, Shah JT, Crawford AL, Welch EB, Rothberg J, Sacolick L, Poole M, Wira C, Matouk CC, Ward A, Timario N, Leasure A, Beekman R, Peng TJ, Witsch J, Antonios JP, Falcone GJ, Gobeske KT, Petersen N, Schindler J, Sansing L, Gilmore EJ, Hwang DY, Kim JA, Malhotra A, Sze G, Rosen MS, Kimberly WT, Sheth KN. Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage Nature Communications 2021, 12: 5119. PMID: 34433813, PMCID: PMC8387402, DOI: 10.1038/s41467-021-25441-6.
- Cardiovascular Health Disparities in Racial and Other Underrepresented Groups: Initial Results From the All of Us Research ProgramAcosta JN, Leasure AC, Both CP, Szejko N, Brown S, Torres‐Lopez V, Abdelhakim S, Schindler J, Petersen N, Sansing L, Gill TM, Sheth KN, Falcone GJ. Cardiovascular Health Disparities in Racial and Other Underrepresented Groups: Initial Results From the All of Us Research Program Journal Of The American Heart Association 2021, 10: e021724. PMID: 34431358, PMCID: PMC8649271, DOI: 10.1161/jaha.121.021724.
- Early Inflammatory Cytokine Expression in Cerebrospinal Fluid of Patients with Spontaneous Intraventricular HemorrhageZiai WC, Parry-Jones AR, Thompson CB, Sansing LH, Mullen MT, Murthy SB, Mould A, Nekoovaght-Tak S, Hanley DF. Early Inflammatory Cytokine Expression in Cerebrospinal Fluid of Patients with Spontaneous Intraventricular Hemorrhage Biomolecules 2021, 11: 1123. PMID: 34439789, PMCID: PMC8394793, DOI: 10.3390/biom11081123.
- Expedited and Comprehensive Management of Low-Risk TIA Patients in the Emergency Department is Safe and Less CostlyGarg A, Maran I, Amin H, Vlieks K, Neuschatz K, Coppola A, Poskus K, Johnson J, Davis M, Minja F, Schindler J, Sansing LH, Malhotra A, Jasne AS, Sharma R. Expedited and Comprehensive Management of Low-Risk TIA Patients in the Emergency Department is Safe and Less Costly Journal Of Stroke And Cerebrovascular Diseases 2021, 30: 106016. PMID: 34325273, DOI: 10.1016/j.jstrokecerebrovasdis.2021.106016.
- Admission computed tomography radiomic signatures outperform hematoma volume in predicting baseline clinical severity and functional outcome in the ATACH‐2 trial intracerebral hemorrhage populationHaider SP, Qureshi AI, Jain A, Tharmaseelan H, Berson ER, Zeevi T, Majidi S, Filippi CG, Iseke S, Gross M, Acosta JN, Malhotra A, Kim JA, Sansing LH, Falcone GJ, Sheth KN, Payabvash S. Admission computed tomography radiomic signatures outperform hematoma volume in predicting baseline clinical severity and functional outcome in the ATACH‐2 trial intracerebral hemorrhage population European Journal Of Neurology 2021, 28: 2989-3000. PMID: 34189814, PMCID: PMC8818333, DOI: 10.1111/ene.15000.
- Intracerebral Hemorrhage in Patients With COVID-19: An Analysis From the COVID-19 Cardiovascular Disease RegistryLeasure AC, Khan YM, Iyer R, Elkind MSV, Sansing LH, Falcone GJ, Sheth KN. Intracerebral Hemorrhage in Patients With COVID-19: An Analysis From the COVID-19 Cardiovascular Disease Registry Stroke 2021, 52: e321-e323. PMID: 34082576, PMCID: PMC8238884, DOI: 10.1161/strokeaha.121.034215.
- Ischemic Stroke, Inflammation, and Endotheliopathy in COVID-19 PatientsMcAlpine LS, Zubair AS, Maran I, Chojecka P, Lleva P, Jasne AS, Navaratnam D, Matouk C, Schindler J, Sheth KN, Chun H, Lee AI, Spudich S, Sharma R, Sansing LH. Ischemic Stroke, Inflammation, and Endotheliopathy in COVID-19 Patients Stroke 2021, 52: e233-e238. PMID: 33966492, PMCID: PMC8140646, DOI: 10.1161/strokeaha.120.031971.
- Divergent Functions of Tissue-Resident and Blood-Derived Macrophages in the Hemorrhagic BrainChang CF, Goods BA, Askenase MH, Beatty HE, Osherov A, DeLong JH, Hammond MD, Massey J, Landreneau M, Love JC, Sansing LH. Divergent Functions of Tissue-Resident and Blood-Derived Macrophages in the Hemorrhagic Brain Stroke 2021, 52: 1798-1808. PMID: 33840225, DOI: 10.1161/strokeaha.120.032196.
- Obstructive Sleep Apnea as a Risk Factor for Intracerebral HemorrhageGeer JH, Falcone GJ, Vanent KN, Leasure AC, Woo D, Molano JR, Sansing LH, Langefeld CD, Pisani MA, Yaggi HK, Sheth KN. Obstructive Sleep Apnea as a Risk Factor for Intracerebral Hemorrhage Stroke 2021, 52: 1835-1838. PMID: 33827242, PMCID: PMC8085039, DOI: 10.1161/strokeaha.120.033342.
- Endothelial cell secreted VEGF-C enhances NSC VEGFR3 expression and promotes NSC survivalMatta R, Feng Y, Sansing LH, Gonzalez AL. Endothelial cell secreted VEGF-C enhances NSC VEGFR3 expression and promotes NSC survival Stem Cell Research 2021, 53: 102318. PMID: 33836422, PMCID: PMC8243729, DOI: 10.1016/j.scr.2021.102318.
- Leukocyte dynamics after intracerebral hemorrhage in a living patient reveal rapid adaptations to tissue milieuGoods BA, Askenase MH, Markarian E, Beatty HE, Drake RS, Fleming I, DeLong JH, Philip NH, Matouk CC, Awad IA, Zuccarello M, Hanley DF, Love JC, Shalek AK, Sansing LH, . Leukocyte dynamics after intracerebral hemorrhage in a living patient reveal rapid adaptations to tissue milieu JCI Insight 2021, 6: e145857. PMID: 33749664, PMCID: PMC8026179, DOI: 10.1172/jci.insight.145857.
- Association of Serum IL-6 (Interleukin 6) With Functional Outcome After Intracerebral HemorrhageLeasure AC, Kuohn LR, Vanent KN, Bevers MB, Kimberly WT, Steiner T, Mayer SA, Matouk CC, Sansing LH, Falcone GJ, Sheth KN. Association of Serum IL-6 (Interleukin 6) With Functional Outcome After Intracerebral Hemorrhage Stroke 2021, 52: 1733-1740. PMID: 33682454, PMCID: PMC8085132, DOI: 10.1161/strokeaha.120.032888.
- Abstract MP40: Klotho -vS Heterozygosity is Associated With Lower Risk of Lobar Intracerebral HemorrhageAcosta J, Szejko N, Both C, Leasure A, Woo D, Langefeld C, Biffi A, Anderson C, Rosand J, Gill T, Sansing L, Sheth K, Falcone G. Abstract MP40: Klotho -vS Heterozygosity is Associated With Lower Risk of Lobar Intracerebral Hemorrhage Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.mp40.
- Abstract P410: Association of Serum GFAP With Hematoma Expansion and Poor Outcome After Intracerebral Hemorrhage: The Factor VII for ICH TrialLeasure A, Vanent K, Bevers M, Kimberly W, Mayer S, Steiner T, Matouk C, Sansing L, Falcone G, Sheth K. Abstract P410: Association of Serum GFAP With Hematoma Expansion and Poor Outcome After Intracerebral Hemorrhage: The Factor VII for ICH Trial Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p410.
- Abstract P412: Klotho -vS Heterozygosity is Associated With Lower Risk of Non-Traumatic Subarachnoid HemorrhageAcosta J, Szejko N, Torres Lopez V, Both C, Sansing L, Sheth K, Matouk C, Gunel M, Falcone G. Abstract P412: Klotho -vS Heterozygosity is Associated With Lower Risk of Non-Traumatic Subarachnoid Hemorrhage Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p412.
- Abstract P510: Ct Angiographic Radiomics Signature Predicts Functional Outcome Following Endovascular Thrombectomy in Large Vessel Occlusion StrokeAvery E, Behland J, Haider S, Zeevi T, Nguyen C, Peshwe K, Petersen N, Falcone G, Sansing L, Malhotra A, Matouk C, Sheth K, Payabvash S. Abstract P510: Ct Angiographic Radiomics Signature Predicts Functional Outcome Following Endovascular Thrombectomy in Large Vessel Occlusion Stroke Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p510.
- Abstract P633: Polygenic Susceptibility to Hypertension is Associated With Uncontrolled and Resistant Hypertension in Stroke SurvivorsAcosta J, Both C, Szejko N, Brown S, Petersen N, Sansing L, Sheth K, Falcone G. Abstract P633: Polygenic Susceptibility to Hypertension is Associated With Uncontrolled and Resistant Hypertension in Stroke Survivors Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p633.
- Abstract P91: Excess Cerebrovascular Mortality in the U.S. During the Covid-19 PandemicSharma R, Kuohn L, Weinberger D, Warren J, Sansing L, Jasne A, Falcone G, Dhand A, Sheth K. Abstract P91: Excess Cerebrovascular Mortality in the U.S. During the Covid-19 Pandemic Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p91.
- Abstract P136: Feasibility and Safety of an Expedited Emergency Department TIA EvaluationGarg A, Maran I, Vlieks K, Neuschatz K, Coppola A, Poskus K, Johnson J, Davis M, Minja F, Jasne A, Sansing L, Schindler J, Malhotra A, Sharma R. Abstract P136: Feasibility and Safety of an Expedited Emergency Department TIA Evaluation Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.p136.
- Abstract MP35: Blood Pressure Reductions Before Arrival at a Thrombectomy-Capable Hospital Are Associated With Neurologic Worsening in Patients With Large-Vessel OcclusionKobsa J, Prasad A, Soto A, Kodali S, Nguyen C, Peshwe K, Quispe-Orozco D, Farooqui M, Zeballos C, Sansing L, Schindler J, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Abstract MP35: Blood Pressure Reductions Before Arrival at a Thrombectomy-Capable Hospital Are Associated With Neurologic Worsening in Patients With Large-Vessel Occlusion Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.mp35.
- Admission Hemoglobin Levels Are Associated With Functional Outcome in Spontaneous Intracerebral Hemorrhage.Acosta JN, Leasure AC, Kuohn LR, Both CP, Petersen NH, Sansing LH, Matouk CC, Testai F, Langefeld CD, Woo D, Kamel H, Murthy SB, Qureshi A, Mayer SA, Sheth KN, Falcone GJ. Admission Hemoglobin Levels Are Associated With Functional Outcome in Spontaneous Intracerebral Hemorrhage. Critical Care Medicine 2021, 49: 828-837. PMID: 33591003, PMCID: PMC8611893, DOI: 10.1097/ccm.0000000000004891.
- Longitudinal transcriptomics define the stages of myeloid activation in the living human brain after intracerebral hemorrhageAskenase MH, Goods BA, Beatty HE, Steinschneider AF, Velazquez SE, Osherov A, Landreneau MJ, Carroll SL, Tran TB, Avram VS, Drake RS, Gatter GJ, Massey JA, Karuppagounder SS, Ratan RR, Matouk CC, Sheth KN, Ziai WC, Parry-Jones AR, Awad IA, Zuccarello M, Thompson RE, Dawson J, Hanley DF, Love JC, Shalek AK, Sansing LH, Barrer S, MacKenzie L, Jonczak K, Bussinger P, Nakaji P, Wright S, Honea N, Zomorodi A, James M, Yeh E, Galicich W, Bergman T, France K, Leiphart J, Ramesh S, Brennan T, Huang J, Ziai W, White M, Camarata P, Abraham M, Gorup J, Reimer R, Freeman W, Williams C, Edwards E, Pollack A, Terry J, Shoen A, Jahromi B, Maas M, Yip B, Amidei C, Muñoz L, Lopez G, Holtz R, Gupta G, Rybinnik I, Moccio M, Lovick D, Brion B, Titus K, Jallo J, Rincon F, Pigott K, Boyden L, Dougherty J, Harrigan M, Miller D, Nelson L, Thompson G, Rajajee V, Pandey A, Ball R, Carlson A, Tran H, Alchbli A, James R, Jerde A, Taussky P, Ansari S, Neate C, Martinez J, Letsinger J, Fagatele L, Eaquinto C, Matouk C, Sheth K, Sansing L, Ryall L, Kunze K, Mampre D, Jasak S, Abdul-Rahim A, Abou-Hamden A, Abraham M, Ahmed A, Alba C, Aldrich E, Ali H, Altschul D, Amin-Hanjani S, Anderson C, Anderson D, Ansari S, Antezana D, Ardelt A, Arikan F, Awad R, Baguena M, Baker A, Barrer S, Barzo P, Becker K, Bergman T, Betz J, Bistran-Hall A, Boström A, Braun J, Brindley P, Broaddus W, Brown R, Buki A, Bulters D, Camarata P, Cao B, Cao Y, Carhuapoma J, Carlson A, Caron J, Carrion-Penagos J, Chalela J, Chang T, Chicoine M, Chorro I, Chowdhry S, Cobb C, Corral L, Csiba L, Davies J, Dawson J, Díaz A, Derdeyn C, Diringer M, Dlugash R, Dodd R, Ecker R, Economas T, Enriquez P, Ezer E, Fan Y, Feng H, Franz D, Freeman W, Fusco M, Galicich W, Gandhi D, Gelea M, Goldstein J, Gonzalez A, Grabarits C, Greenberg S, Gregson B, Gress D, Gu E, Gupta G, Hall C, Hanley D, Hao Y, Harnof S, Harrigan M, Hernandez F, Hoesch R, Hoh B, Houser J, Hu R, Huang J, Huang Y, Hussain M, Insinga S, Jadhav A, Jaffe J, Jahromi B, Jallo J, James M, James R, Janis S, Jankowitz B, Jeon E, Jichici D, Jonczak K, Jonker B, Karlen N, Kase C, Keric N, Kerz T, Kitagawa R, Knopman J, Koenig C, Krishnamurthy S, Kumar A, Kureshi I, Laidlaw J, Lakhanpal A, Lane K, Latorre J, LeDoux D, Lees K, Leifer D, Leiphart J, Lenington S, Li Y, Lopez G, Lovick D, Lumenta C, Luo J, Maas M, MacDonald J, MacKenzie L, Madan V, Majkowski R, Major O, Malhorta R, Malkoff M, Mangat H, Maswadeh A, Matouk C, Mayo S, McArthur K, McBee N, McCaul S, Medow J, Mendelow A, Mezey G, Mighty J, Miller D, Mitchell P, Mohan K, Money P, Mould W, Muir K, Muñoz L, Nakaji P, Nee A, Nekoovaght-Tak S, Nyquist P, O’Kane R, Okasha M, O'Kelly C, Ostapkovich N, Pandey A, Parry-Jones A, Patel H, Perla K, Pollack A, Polster S, Pouratian N, Quinn T, Rajajee V, Reddy K, Rehman M, Reimer R, Rincon F, Rosenblum M, Rybinnik I, Sanchez B, Sansing L, Sarabia R, Schneck M, Schuerer L, Schul D, Schweitzer J, Seder D, Seyfried D, Sheth K, Spiotta A, Stadnik A, Stechison M, Sugar E, Szabo K, Tamayo G, Tanczos K, Taussky P, Teitelbaum J, Terry J, Testai F, Thomas K, Thompson C, Thompson G, Thompson R, Torner J, Tran H, Tucker K, Ullman N, Ungar L, Unterberg A, Varelas P, Vargas N, Vatter H, Venkatasubramanian C, Vermillion K, Vespa P, Vollmer D, Wang W, Wang Y, Wang Y, Wen J, Whitworth L, Willis B, Wilson A, Wolfe S, Wrencher M, Wright S, Xu Y, Yanase L, Yenokyan G, Yi X, Yu Z, Ziai W, Zomorodi A, Zuccarello M. Longitudinal transcriptomics define the stages of myeloid activation in the living human brain after intracerebral hemorrhage Science Immunology 2021, 6 PMID: 33891558, PMCID: PMC8252865, DOI: 10.1126/sciimmunol.abd6279.
- Intracerebral Hemorrhage with Intraventricular Extension Associated with Loss of Consciousness at Symptom OnsetWitsch J, Falcone GJ, Leasure AC, Matouk C, Endres M, Sansing L, Woo D, Sheth KN. Intracerebral Hemorrhage with Intraventricular Extension Associated with Loss of Consciousness at Symptom Onset Neurocritical Care 2021, 35: 418-427. PMID: 33479920, PMCID: PMC8578176, DOI: 10.1007/s12028-020-01180-2.
- Excess Cerebrovascular Mortality in the United States During the COVID-19 PandemicSharma R, Kuohn LR, Weinberger DM, Warren JL, Sansing LH, Jasne A, Falcone G, Dhand A, Sheth KN. Excess Cerebrovascular Mortality in the United States During the COVID-19 Pandemic Stroke 2021, 52: 563-572. PMID: 33430638, PMCID: PMC7834664, DOI: 10.1161/strokeaha.120.031975.
- Chronic Stress Weakens Connectivity in the Prefrontal Cortex: Architectural and Molecular ChangesWoo E, Sansing LH, Arnsten AFT, Datta D. Chronic Stress Weakens Connectivity in the Prefrontal Cortex: Architectural and Molecular Changes Chronic Stress 2021, 5: 24705470211029254. PMID: 34485797, PMCID: PMC8408896, DOI: 10.1177/24705470211029254.
- 30-Day Outcomes of Trans-Carotid Artery Revascularization with Proximal Protection Through ICA Flow Reversal in Neurosurgical PracticeCord B, Santarosa C, Sujijantarat N, Koo A, Elsamadicy A, Sheth K, Falcone G, Sansing L, Schindler J, Petersen N, Matouk C. 30-Day Outcomes of Trans-Carotid Artery Revascularization with Proximal Protection Through ICA Flow Reversal in Neurosurgical Practice Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_334.
- Impact of Clot Location on Outcomes after Mechanical Thrombectomy for Anterior Circulation Acute Ischemic StrokeSujijantarat N, Koo A, Elsamadicy A, Hebert R, Cord B, Navaratnam D, Sansing L, Malhotra A, Matouk C. Impact of Clot Location on Outcomes after Mechanical Thrombectomy for Anterior Circulation Acute Ischemic Stroke Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_387.
- Plasma neurofilament light predicts mortality in patients with strokeGendron TF, Badi MK, Heckman MG, Jansen-West KR, Vilanilam GK, Johnson PW, Burch AR, Walton RL, Ross OA, Brott TG, Miller TM, Berry JD, Nicholson KA, Wszolek ZK, Oskarsson BE, Sheth KN, Sansing LH, Falcone GJ, Cucchiara BL, Meschia JF, Petrucelli L. Plasma neurofilament light predicts mortality in patients with stroke Science Translational Medicine 2020, 12 PMID: 33177179, PMCID: PMC9534269, DOI: 10.1126/scitranslmed.aay1913.
- Cause of death in spontaneous intracerebral hemorrhage survivors: Multistate longitudinal study.Kuohn LR, Leasure AC, Acosta JN, Vanent K, Murthy SB, Kamel H, Matouk CC, Sansing LH, Falcone GJ, Sheth KN. Cause of death in spontaneous intracerebral hemorrhage survivors: Multistate longitudinal study. Neurology 2020, 95: e2736-e2745. PMID: 32917797, PMCID: PMC7734723, DOI: 10.1212/wnl.0000000000010736.
- Assessment of Brain Injury Using Portable, Low-Field Magnetic Resonance Imaging at the Bedside of Critically Ill PatientsSheth KN, Mazurek MH, Yuen MM, Cahn BA, Shah JT, Ward A, Kim JA, Gilmore EJ, Falcone GJ, Petersen N, Gobeske KT, Kaddouh F, Hwang DY, Schindler J, Sansing L, Matouk C, Rothberg J, Sze G, Siner J, Rosen MS, Spudich S, Kimberly WT. Assessment of Brain Injury Using Portable, Low-Field Magnetic Resonance Imaging at the Bedside of Critically Ill Patients JAMA Neurology 2020, 78: 41-47. PMID: 32897296, PMCID: PMC7489395, DOI: 10.1001/jamaneurol.2020.3263.
- Direct carotid puncture for mechanical thrombectomy in acute ischemic stroke patients with prohibitive vascular access.Cord BJ, Kodali S, Strander S, Silverman A, Wang A, Chouairi F, Koo AB, Nguyen CK, Peshwe K, Kimmel A, Porto CM, Hebert RM, Falcone GJ, Sheth KN, Sansing LH, Schindler JL, Matouk CC, Petersen NH. Direct carotid puncture for mechanical thrombectomy in acute ischemic stroke patients with prohibitive vascular access. Journal Of Neurosurgery 2020, 135: 53-63. PMID: 32796146, PMCID: PMC9491727, DOI: 10.3171/2020.5.jns192737.
- Effects of Collateral Status on Infarct Distribution Following Endovascular Therapy in Large Vessel Occlusion StrokeAl-Dasuqi K, Payabvash S, Torres-Flores GA, Strander SM, Nguyen CK, Peshwe KU, Kodali S, Silverman A, Malhotra A, Johnson MH, Matouk CC, Schindler JL, Sansing LH, Falcone GJ, Sheth KN, Petersen NH. Effects of Collateral Status on Infarct Distribution Following Endovascular Therapy in Large Vessel Occlusion Stroke Stroke 2020, 51: e193-e202. PMID: 32781941, PMCID: PMC7484023, DOI: 10.1161/strokeaha.120.029892.
- Stroke Code Presentations, Interventions, and Outcomes Before and During the COVID-19 PandemicJasne AS, Chojecka P, Maran I, Mageid R, Eldokmak M, Zhang Q, Nystrom K, Vlieks K, Askenase M, Petersen N, Falcone GJ, Wira CR, Lleva P, Zeevi N, Narula R, Amin H, Navaratnam D, Loomis C, Hwang DY, Schindler J, Hebert R, Matouk C, Krumholz HM, Spudich S, Sheth KN, Sansing LH, Sharma R. Stroke Code Presentations, Interventions, and Outcomes Before and During the COVID-19 Pandemic Stroke 2020, 51: 2664-2673. PMID: 32755347, PMCID: PMC7446978, DOI: 10.1161/str.0000000000000347.
- Preserving stroke care during the COVID-19 pandemic: Potential issues and solutions.Leira EC, Russman AN, Biller J, Brown DL, Bushnell CD, Caso V, Chamorro A, Creutzfeldt CJ, Cruz-Flores S, Elkind MSV, Fayad P, Froehler MT, Goldstein LB, Gonzales NR, Kaskie B, Khatri P, Livesay S, Liebeskind DS, Majersik JJ, Moheet AM, Romano JG, Sanossian N, Sansing LH, Silver B, Simpkins AN, Smith W, Tirschwell DL, Wang DZ, Yavagal DR, Worrall BB. Preserving stroke care during the COVID-19 pandemic: Potential issues and solutions. Neurology 2020, 95: 124-133. PMID: 32385186, PMCID: PMC7455350, DOI: 10.1212/wnl.0000000000009713.
- Genetically Elevated LDL Associates with Lower Risk of Intracerebral HemorrhageFalcone GJ, Kirsch E, Acosta JN, Noche RB, Leasure A, Marini S, Chung J, Selim M, Meschia JF, Brown DL, Worrall BB, Tirschwell DL, Jagiella JM, Schmidt H, Jimenez‐Conde J, Fernandez‐Cadenas I, Lindgren A, Slowik A, Gill D, Holmes M, Phuah C, Petersen NH, Matouk CN, Gunel M, Sansing L, Bennett D, Chen Z, Sun LL, Clarke R, Walters RG, Gill TM, Biffi A, Kathiresan S, Langefeld CD, Woo D, Rosand J, Sheth KN, Anderson CD, Consortium F. Genetically Elevated LDL Associates with Lower Risk of Intracerebral Hemorrhage Annals Of Neurology 2020, 88: 56-66. PMID: 32277781, PMCID: PMC7523882, DOI: 10.1002/ana.25740.
- Obstructive Sleep Apnea: A Prevalent and Novel Risk Factor for Intracerebral HemorrhageGeer J, Vanent K, Leasure A, Pisani M, Sansing L, Woo D, Langefeld C, Falcone G, Sheth K, Yaggi H. Obstructive Sleep Apnea: A Prevalent and Novel Risk Factor for Intracerebral Hemorrhage 2020, a2713-a2713. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2713.
- Response by Chang and Sansing to Letter Regarding Article, “Bexarotene Enhances Macrophage Erythrophagocytosis and Hematoma Clearance in Experimental Intracerebral Hemorrhage”Chang CF, Sansing LH. Response by Chang and Sansing to Letter Regarding Article, “Bexarotene Enhances Macrophage Erythrophagocytosis and Hematoma Clearance in Experimental Intracerebral Hemorrhage” Stroke 2020, 51: e88. PMID: 32299318, PMCID: PMC8059296, DOI: 10.1161/strokeaha.120.029256.
- Fixed Compared With Autoregulation-Oriented Blood Pressure Thresholds After Mechanical Thrombectomy for Ischemic StrokePetersen NH, Silverman A, Strander SM, Kodali S, Wang A, Sansing LH, Schindler JL, Falcone GJ, Gilmore EJ, Jasne AS, Cord B, Hebert RM, Johnson M, Matouk CC, Sheth KN. Fixed Compared With Autoregulation-Oriented Blood Pressure Thresholds After Mechanical Thrombectomy for Ischemic Stroke Stroke 2020, 51: 914-921. PMID: 32078493, PMCID: PMC7050651, DOI: 10.1161/strokeaha.119.026596.
- Abstract 117: Fixed Compared to Autoregulation-oriented Blood Pressure Thresholds After Mechanical Thrombectomy for Ischemic StrokePetersen N, Silverman A, Strander S, Kodali S, Wang A, Sansing L, Schindler J, Falcone G, Gilmore E, Jasne A, Cord B, Hebert R, Johnson M, Matouk C, Sheth K. Abstract 117: Fixed Compared to Autoregulation-oriented Blood Pressure Thresholds After Mechanical Thrombectomy for Ischemic Stroke Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.117.
- Abstract 156: Recurrent Stroke in Middle-Aged Lacunar Stroke Survivors: Understanding Risk Factors and Vulnerability in an Important Target PopulationNoche R, Biffi A, Sansing L, Shoamanesh A, Benavente O, Falcone G, Sheth K. Abstract 156: Recurrent Stroke in Middle-Aged Lacunar Stroke Survivors: Understanding Risk Factors and Vulnerability in an Important Target Population Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.156.
- Abstract 57: Deployment of Portable, Bedside, Low-Field Magnetic Resonance Imaging for Evaluation of Stroke PatientsCahn B, Shah J, Dyvorne H, O'Halloran R, Poole M, Yuen M, Mazurek M, Ward A, Payabvash S, Beekman R, Brown S, Falcone G, Gobeske K, Petersen N, Jasne A, Sharma R, Schindler J, Sansing L, Gilmore E, Wira C, Matouk C, Sze G, Rosen M, Kimberly W, Sheth K. Abstract 57: Deployment of Portable, Bedside, Low-Field Magnetic Resonance Imaging for Evaluation of Stroke Patients Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.57.
- Abstract 71: Sex and Genetic Predisposition Synergistically Influence Risk of Stroke and Myocardial Infarction in Middle-Aged Persons Without Risk FactorsFalcone G, Acosta J, Leasure A, Vanent K, Noche R, Kirsch E, Petersen N, Schindler J, Sansing L, Gill T, Matouk C, Gunel M, Sheth K. Abstract 71: Sex and Genetic Predisposition Synergistically Influence Risk of Stroke and Myocardial Infarction in Middle-Aged Persons Without Risk Factors Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.71.
- Abstract TP347: Obstructive Sleep Apnea Frequency in Intracerebral HemorrhageGeer J, Leasure A, Vanent K, Sansing L, Woo D, Langefeld C, Yaggi H, Falcone G, Sheth K. Abstract TP347: Obstructive Sleep Apnea Frequency in Intracerebral Hemorrhage Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp347.
- Abstract WMP101: Prediction of Clinical Outcome in Supratentorial Intracerebral Hemorrhage: Application of Baseline Ct Scan Radiomics Feature Extraction and Machine Learning ClassifiersPayabvash S, Acosta J, Haider S, Noche R, Kirsch E, Matouk C, Sansing L, Sheth K, Falcone G. Abstract WMP101: Prediction of Clinical Outcome in Supratentorial Intracerebral Hemorrhage: Application of Baseline Ct Scan Radiomics Feature Extraction and Machine Learning Classifiers Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wmp101.
- Abstract WP11: Timing of Blood Pressure Decreases During Mechanical Thrombectomy for Ischemic StrokeKimmel A, Silverman A, Kodali S, Strander S, Nguyen C, Peshwe K, Wang A, Lopez G, Holcombe A, Zevallos C, Dandapat S, Sansing L, Schindler J, Falcone G, Matouk C, Sheth K, Ortega-Gutiérrez S, Petersen N. Abstract WP11: Timing of Blood Pressure Decreases During Mechanical Thrombectomy for Ischemic Stroke Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp11.
- Abstract WP400: Causes of Death in a Longitudinal Analysis of Spontaneous Intracerebral Hemorrhage SurvivorsKuohn L, Leasure A, Acosta J, Vanent K, Murthy S, Kamel H, Matouk C, Sansing L, Falcone G, Sheth K. Abstract WP400: Causes of Death in a Longitudinal Analysis of Spontaneous Intracerebral Hemorrhage Survivors Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp400.
- Abstract WP410: Hemoglobin Levels and Poor Outcome in Intracerebral Hemorrhage: An Exploratory Analysis of Individual Patient Data Across Multiple StudiesAcosta J, Leasure A, Kuohn L, Petersen N, Sansing L, Matouk C, Testai F, Langefeld C, Woo D, Qureshi A, Mayer S, Sheth K, Falcone G. Abstract WP410: Hemoglobin Levels and Poor Outcome in Intracerebral Hemorrhage: An Exploratory Analysis of Individual Patient Data Across Multiple Studies Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp410.
- Abstract TMP89: Impaired Cerebral Autoregulation Increases Risk of Worse Outcome After Endovascular Thrombectomy in Stroke Patients With High Blood Pressure VariabilityNguyen C, Silverman A, Wang A, Kodali S, Strander S, Kimmel A, Peshwe K, De Havenon A, Gilmore E, Matouk C, Sansing L, Schindler J, Sheth K, Petersen N. Abstract TMP89: Impaired Cerebral Autoregulation Increases Risk of Worse Outcome After Endovascular Thrombectomy in Stroke Patients With High Blood Pressure Variability Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tmp89.
- Abstract TP11: CTA Collateral Status and Final Infarct Distribution Following Thrombectomy in Stroke Patients With Large Vessel OcclusionAl-Dasuqi K, Payabvash S, Abou Karam A, Strander S, Kodali S, Silverman A, Sansing L, Schindler J, Matouk C, Sheth K, Malhotra A, Petersen N. Abstract TP11: CTA Collateral Status and Final Infarct Distribution Following Thrombectomy in Stroke Patients With Large Vessel Occlusion Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp11.
- Abstract TP40: Time From Stroke Onset to Reperfusion is Associated With Worse Functional Outcomes in Patients With Rapidly Progressing InfarctsWang A, Strander S, Kodali S, Silverman A, Kimmel A, Nguyen C, Peshwe K, Sansing L, Schindler J, Matouk C, Sheth K, Petersen N. Abstract TP40: Time From Stroke Onset to Reperfusion is Associated With Worse Functional Outcomes in Patients With Rapidly Progressing Infarcts Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp40.
- Abstract WP374: High Frequency Blood Pressure Monitoring in the Acute Phase of Large Vessel Occlusion Ischemic StrokePeshwe K, Nguyen C, Kimmel A, Kodali S, Silverman A, Strander S, Wang A, Wira C, Sansing L, Matouk C, Sheth K, Petersen N. Abstract WP374: High Frequency Blood Pressure Monitoring in the Acute Phase of Large Vessel Occlusion Ischemic Stroke Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp374.
- Abstract WP413: Portable, Bedside, Point of Care Magnetic Resonance Imaging in an Intensive Care Setting for Intracranial HemorrhageCahn B, Shah J, By S, Welch E, Sacolick L, Yuen M, Mazurek M, Wira C, Leasure A, Matouk C, Ward A, Payabvash S, Beekman R, Brown S, Falcone G, Gobeske K, Petersen N, Jasne A, Sharma R, Schindler J, Sansing L, Gilmore E, Sze G, Rosen M, Kimberly W, Sheth K. Abstract WP413: Portable, Bedside, Point of Care Magnetic Resonance Imaging in an Intensive Care Setting for Intracranial Hemorrhage Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.wp413.
- Abstract 178: Cholesterol Limits Macrophage Activation in Response to Intracerebral Hemorrhage-Relevant SignalsDeLong J, Velazquez S, Landreneau M, Sansing L. Abstract 178: Cholesterol Limits Macrophage Activation in Response to Intracerebral Hemorrhage-Relevant Signals Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.178.
- Depletion of CD4 T cells provides therapeutic benefits in aged mice after ischemic strokeHarris NM, Roy-O'Reilly M, Ritzel RM, Holmes A, Sansing LH, O'Keefe LM, McCullough LD, Chauhan A. Depletion of CD4 T cells provides therapeutic benefits in aged mice after ischemic stroke Experimental Neurology 2020, 326: 113202. PMID: 31954116, PMCID: PMC7059209, DOI: 10.1016/j.expneurol.2020.113202.
- Aging exacerbates neutrophil pathogenicity in ischemic strokeRoy-O'Reilly MA, Ahnstedt H, Spychala MS, Munshi Y, Aronowski J, Sansing LH, McCullough LD. Aging exacerbates neutrophil pathogenicity in ischemic stroke Aging 2020, 12: 436-461. PMID: 31927534, PMCID: PMC6977697, DOI: 10.18632/aging.102632.
- Racial/ethnic disparities in the risk of intracerebral hemorrhage recurrence.Leasure AC, King ZA, Torres-Lopez V, Murthy SB, Kamel H, Shoamanesh A, Al-Shahi Salman R, Rosand J, Ziai WC, Hanley DF, Woo D, Matouk CC, Sansing LH, Falcone GJ, Sheth KN. Racial/ethnic disparities in the risk of intracerebral hemorrhage recurrence. Neurology 2019, 94: e314-e322. PMID: 31831597, PMCID: PMC7108806, DOI: 10.1212/wnl.0000000000008737.
- Bexarotene Enhances Macrophage Erythrophagocytosis and Hematoma Clearance in Experimental Intracerebral HemorrhageChang CF, Massey J, Osherov A, Angenendt da Costa LH, Sansing LH. Bexarotene Enhances Macrophage Erythrophagocytosis and Hematoma Clearance in Experimental Intracerebral Hemorrhage Stroke 2019, 51: 612-618. PMID: 31826730, PMCID: PMC7135897, DOI: 10.1161/strokeaha.119.027037.
- Perihematomal Edema After Intracerebral Hemorrhage in Patients With Active MalignancyGusdon AM, Nyquist PA, Torres-Lopez VM, Leasure AC, Falcone GJ, Sheth KN, Sansing LH, Hanley DF, Malani R. Perihematomal Edema After Intracerebral Hemorrhage in Patients With Active Malignancy Stroke 2019, 51: 129-136. PMID: 31744426, PMCID: PMC7048624, DOI: 10.1161/strokeaha.119.027085.
- Transforming growth factor-β promotes basement membrane fibrosis, alters perivascular cerebrospinal fluid distribution, and worsens neurological recovery in the aged brain after strokeHowe MD, Furr JW, Munshi Y, Roy-O’Reilly M, Maniskas ME, Koellhoffer EC, d’Aigle J, Sansing LH, McCullough LD, Urayama A. Transforming growth factor-β promotes basement membrane fibrosis, alters perivascular cerebrospinal fluid distribution, and worsens neurological recovery in the aged brain after stroke GeroScience 2019, 41: 543-559. PMID: 31721012, PMCID: PMC6885082, DOI: 10.1007/s11357-019-00118-7.
- Antiplatelet Therapy After Spontaneous Intracerebral Hemorrhage and Functional OutcomesMurthy SB, Biffi A, Falcone GJ, Sansing LH, Torres Lopez V, Navi BB, Roh DJ, Mandava P, Hanley DF, Ziai WC, Kamel H, Rosand J, Sheth KN, Butcher K, Davis S, Gregson B, Lees K, Lyden P, Mayer S, Muir K, Steiner T. Antiplatelet Therapy After Spontaneous Intracerebral Hemorrhage and Functional Outcomes Stroke 2019, 50: 3057-3063. PMID: 31895618, PMCID: PMC6941441, DOI: 10.1161/strokeaha.119.025972.
- Percutaneous Trans-Carotid Puncture for Mechanical Thrombectomy in Acute Ischemic Stroke Patients is Safe and Effective: A Large, Single-Center Case SeriesCord B, Wang A, Chouairi F, Koo A, Porto C, Silverman A, Kodali S, Strander S, Falcone G, Sheth K, Hebert R, Sansing L, Schindler J, Petersen N, Matouk C. Percutaneous Trans-Carotid Puncture for Mechanical Thrombectomy in Acute Ischemic Stroke Patients is Safe and Effective: A Large, Single-Center Case Series Neurosurgery 2019, 66: 310-167. DOI: 10.1093/neuros/nyz310_167.
- Preliminary Experience With Proximal Flow Reversal During Intracranial Balloon Angioplasty and Stenting for Symptomatic, Severe Intracranial StenosisCord B, Santarosa C, Sujijantarat N, Kundishora A, Falcone G, Sheth K, Sansing L, Schindler J, Petersen N, Matouk C. Preliminary Experience With Proximal Flow Reversal During Intracranial Balloon Angioplasty and Stenting for Symptomatic, Severe Intracranial Stenosis Neurosurgery 2019, 66: 310-675. DOI: 10.1093/neuros/nyz310_675.
- Surgical Performance Determines Functional Outcome Benefit in the Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation (MISTIE) ProcedureAwad I, Polster S, Carrión-Penagos J, Thompson R, Cao Y, Stadnik A, Money P, Fam M, Koskimäki J, Girard R, Lane K, McBee N, Ziai W, Hao Y, Dodd R, Carlson A, Camarata P, Caron J, Harrigan M, Gregson B, Mendelow A, Zuccarello M, Hanley D, Abdul-Rahim A, Abou-Hamden A, Abraham M, Ahmed A, Alba C, Aldrich E, Ali H, Altschul D, Amin-Hanjani S, Anderson C, Anderson D, Ansari S, Antezana D, Ardelt A, Arikan F, Avadhani R, Baguena M, Baker A, Barrer S, Barzo P, Becker K, Bergman T, Betz J, Bistran-Hall A, Boström A, Braun J, Brindley P, Broaddus W, Brown R, Buki A, Bulters D, Cao B, Carhuapoma J, Chalela J, Chang T, Chicoine M, Chorro I, Chowdhry S, Cobb C, Corral L, Csiba L, Davies J, Dawson J, Díaz A, Dierdeyn C, Diringer M, Dlugash R, Ecker R, Economas T, Enriquez P, Ezer E, Fan Y, Feng H, Franz D, Freeman W, Fusco M, Galicich W, Gandhi D, Gelea M, Goldstein J, Gonzalez A, Grabarits C, Greenberg S, Gregson B, Gress D, Gu E, Gupta G, Hall C, Harnof S, Hernandez F, Hoesch R, Hoh B, Houser J, Hu R, Huang J, Huang Y, Hussain M, Insinga S, Jadhav A, Jaffe J, Jahromi B, Jallo J, James M, James R, Janis S, Jankowitz B, Jeon E, Jichici D, Jonczak K, Jonker B, Karlen N, Kase C, Keric N, Kerz T, Kitagawa R, Knopman J, Koenig C, Krishnamurthy S, Kumar A, Kureshi I, Laidlaw J, Lakhanpal A, Latorre J, LeDoux D, Lees K, Leifer D, Leiphart J, Lenington S, Li Y, Lopez G, Lovick D, Lumenta C, Luo J, Maas M, MacDonald J, MacKenzie L, Madan V, Majkowski R, Major O, Malhorta R, Malkoff M, Mangat H, Maswadeh A, Matouk C, Mayo S, McArthur K, McCaul S, Medow J, Mezey G, Mighty J, Miller D, Mitchell P, Mohan K, Mould W, Muir K, Muñoz L, Nakaji P, Nee A, Nekoovaght-Tak S, Nyquist P, O'Kane R, Okasha M, O'Kelly C, Ostapkovich N, Pandey A, Parry-Jones A, Patel H, Perla K, Pollack A, Pouratian N, Quinn T, Rajajee V, Reddy K, Rehman M, Reimer R, Rincon F, Rosenblum M, Rybinnik I, Sanchez B, Sansing L, Sarabia R, Schneck M, Schuerer L, Schul D, Schweitzer J, Seder D, Seyfried D, Sheth K, Spiotta A, Stechison M, Sugar E, Szabo K, Tamayo G, Tanczos K, Taussky P, Teitelbaum J, Terry J, Testai F, Thomas K, Thompson C, Thompson G, Torner J, Tran H, Tucker K, Ullman N, Ungar L, Unterberg A, Varelas P, Vargas N, Vatter H, Venkatasubramanian C, Vermillion K, Vespa P, Vollmer D, Wang W, Wang Y, Wang Y, Wen J, Whitworth L, Willis B, Wilson A, Wolfe S, Wrencher M, Wright S, Xu Y, Yanase L, Yenokyan G, Yi X, Yu Z, Zomorodi A. Surgical Performance Determines Functional Outcome Benefit in the Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation (MISTIE) Procedure Neurosurgery 2019, 84: nyz077-. PMID: 30891610, PMCID: PMC6537634, DOI: 10.1093/neuros/nyz077.
- Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trialHanley D, Thompson R, Rosenblum M, Yenokyan G, Lane K, McBee N, Mayo S, Bistran-Hall A, Gandhi D, Mould W, Ullman N, Ali H, Carhuapoma J, Kase C, Lees K, Dawson J, Wilson A, Betz J, Sugar E, Hao Y, Avadhani R, Caron J, Harrigan M, Carlson A, Bulters D, LeDoux D, Huang J, Cobb C, Gupta G, Kitagawa R, Chicoine M, Patel H, Dodd R, Camarata P, Wolfe S, Stadnik A, Money P, Mitchell P, Sarabia R, Harnof S, Barzo P, Unterberg A, Teitelbaum J, Wang W, Anderson C, Mendelow A, Gregson B, Janis S, Vespa P, Ziai W, Zuccarello M, Awad I, Investigators M, Abdul-Rahim A, Abou-Hamden A, Abraham M, Ahmed A, Alba C, Aldrich E, Altschul D, Amin-Hanjani S, Anderson D, Ansari S, Antezana D, Ardelt A, Arikan F, Baguena M, Baker A, Barrer S, Becker K, Bergman T, Boström A, Braun J, Brindley P, Broaddus W, Brown R, Buki A, Cao B, Cao Y, Carrion-Penagos J, Chalela J, Chang T, Chorro I, Chowdhry S, Corral L, Csiba L, Davies J, Díaz A, Derdeyn C, Diringer M, Dlugash R, Ecker R, Economas T, Enriquez P, Ezer E, Fan Y, Feng H, Franz D, Freeman W, Fusco M, Galicich W, Gelea M, Goldstein J, Gonzalez A, Grabarits C, Greenberg S, Gress D, Gu E, Hall C, Hernandez F, Hoesch R, Hoh B, Houser J, Hu R, Huang Y, Hussain M, Insinga S, Jadhav A, Jaffe J, Jahromi B, Jallo J, James M, James R, Jankowitz B, Jeon E, Jichici D, Jonczak K, Jonker B, Karlen N, Keric N, Kerz T, Knopman J, Koenig C, Krishnamurthy S, Kumar A, Kureshi I, Laidlaw J, Lakhanpal A, Latorre J, Leifer D, Leiphart J, Lenington S, Li Y, Lopez G, Lovick D, Lumenta C, Luo J, Maas M, MacDonald J, MacKenzie L, Madan V, Majkowski R, Major O, Malhorta R, Malkoff M, Mangat H, Maswadeh A, Matouk C, McArthur K, McCaul S, Medow J, Mezey G, Mighty J, Miller D, Mohan K, Muir K, Muñoz L, Nakaji P, Nee A, Nekoovaght-Tak S, Nyquist P, O'Kane R, Okasha M, O'Kelly C, Ostapkovich N, Pandey A, Parry-Jones A, Perla K, Pollack A, Polster S, Pouratian N, Quinn T, Rajajee V, Reddy K, Rehman M, Reimer R, Rincon F, Rybinnik I, Sanchez B, Sansing L, Schneck M, Schuerer L, Schul D, Schweitzer J, Seder D, Seyfried D, Sheth K, Spiotta A, Stechison M, Szabo K, Tamayo G, Tanczos K, Taussky P, Terry J, Testai F, Thomas K, Thompson C, Thompson G, Torner J, Tran H, Tucker K, Ungar L, Varelas P, Vargas N, Vatter H, Venkatasubramanian C, Vermillion K, Vollmer D, Wang Y, Wang Y, Wen J, Whitworth L, Willis B, Wrencher M, Wright S, Xu Y, Yanase L, Yi X, Yu Z, Zomorodi A. Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial The Lancet 2019, 393: 1021-1032. PMID: 30739747, PMCID: PMC6894906, DOI: 10.1016/s0140-6736(19)30195-3.
- Abstract 18: Genetically-Determined Cholesterol Levels are Associated with Risk of Spontaneous Intracerebral HemorrhageKirsch E, Leasure A, Matouk C, Sansing L, Crawford K, Kourkoulis C, Woo D, Rosand J, Anderson C, Sheth K, Falcone G. Abstract 18: Genetically-Determined Cholesterol Levels are Associated with Risk of Spontaneous Intracerebral Hemorrhage Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.18.
- Abstract 76: Intensive Blood Pressure Reduction is Associated With Reduced Hematoma Expansion in Deep Intracerebral Hemorrhage: A Secondary Analysis of ATACH-2Leasure A, Qureshi A, Goldstein J, Murthy S, Kamel H, Woo D, Matouk C, Sansing L, Sheth K, Falcone G. Abstract 76: Intensive Blood Pressure Reduction is Associated With Reduced Hematoma Expansion in Deep Intracerebral Hemorrhage: A Secondary Analysis of ATACH-2 Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.76.
- Abstract 77: Perihematomal Edema Expansion Rate is Associated With Poor Functional Outcomes in Basal Ganglia Intracerebral HemorrhageLeasure A, Qureshi A, Goldstein J, Murthy S, Kamel H, Woo D, Matouk C, Sansing L, Falcone G, Sheth K. Abstract 77: Perihematomal Edema Expansion Rate is Associated With Poor Functional Outcomes in Basal Ganglia Intracerebral Hemorrhage Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.77.
- Abstract TP15: Percutaneous Transcarotid Puncture is a Viable Alternative for Thrombectomy in Acute Ischemic Stroke Patients With Difficult Vascular AccessWang A, Cord B, Chouairi F, Koo A, Porto C, Silverman A, Kodali S, Strander S, Hebert R, Falcone G, Sheth K, Sansing L, Schindler J, Matouk C, Petersen N. Abstract TP15: Percutaneous Transcarotid Puncture is a Viable Alternative for Thrombectomy in Acute Ischemic Stroke Patients With Difficult Vascular Access Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.tp15.
- Abstract WMP97: Racial/Ethnic Disparities in the Risk of Intracerebral Hemorrhage RecurrenceKing Z, Leasure A, Torres-Lopez V, Woo D, Hanley D, Ziai W, Murthy S, Matouk C, Sansing L, Falcone G, Sheth K. Abstract WMP97: Racial/Ethnic Disparities in the Risk of Intracerebral Hemorrhage Recurrence Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.wmp97.
- Abstract WP223: Ischemic and Hemorrhagic Stroke in Native AmericansKing Z, Beekman R, Chu S, Leasure A, Orgrass H, Gilmore E, Sansing L, Matouk C, Sheth K, Falcone G. Abstract WP223: Ischemic and Hemorrhagic Stroke in Native Americans Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.wp223.
- Abstract 95: Exceeding Personalized Blood Pressure Targets After Endovascular Stroke Therapy is Associated With Hemorrhagic Transformation and Worse Functional OutcomePetersen N, Wang A, Strander S, Kodali S, Silverman A, Gilmore E, Sansing L, Schindler J, Hebert R, Cord B, Matouk C, Sheth K. Abstract 95: Exceeding Personalized Blood Pressure Targets After Endovascular Stroke Therapy is Associated With Hemorrhagic Transformation and Worse Functional Outcome Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.95.
- Abstract TP34: Malignant CT Perfusion Profile is Associated With Increased Sensitivity to Blood Pressure Reductions During Endovascular Stroke TherapyStrander S, Wang A, Kodali S, Silverman A, Agarwal T, Stretz C, Zheng-Lin B, Lopez Cardenas G, Sansing L, Schindler J, Matouk C, Hebert R, Sheth K, Ortega Gutierrez S, Petersen N. Abstract TP34: Malignant CT Perfusion Profile is Associated With Increased Sensitivity to Blood Pressure Reductions During Endovascular Stroke Therapy Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.tp34.
- Abstract WP3: Decreases in Blood Pressure During Endovascular Stroke Therapy are Associated With Larger Infarct Volumes and Poor Functional OutcomePetersen N, Wang A, Zhen-Li B, Strander S, Kodali S, Silverman A, Sansing L, Lopez G, Schindler J, Matouk C, Hebert R, Sheth K, Ortega Gutierrez S. Abstract WP3: Decreases in Blood Pressure During Endovascular Stroke Therapy are Associated With Larger Infarct Volumes and Poor Functional Outcome Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.wp3.
- Abstract TP411: Distinct Systolic Blood Pressure Trajectories 72 Hours After Mechanical Thrombectomy Predict Hemorrhagic Transformation and Poor Functional OutcomeKodali S, Wang A, Strander S, Silverman A, Agarwal T, Stretz C, Sansing L, Schindler J, Sheth K, Petersen N. Abstract TP411: Distinct Systolic Blood Pressure Trajectories 72 Hours After Mechanical Thrombectomy Predict Hemorrhagic Transformation and Poor Functional Outcome Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.tp411.
- Elevated Levels of CD64 MFI on Monocyte Subsets Are Associated with a History of Stroke in Sickle Cell DiseaseCurtis S, Balbuena-Merle R, Devine L, Zelterman D, Roberts J, Dearborn-Tomazos J, Sansing L, Hendrickson J. Elevated Levels of CD64 MFI on Monocyte Subsets Are Associated with a History of Stroke in Sickle Cell Disease Blood 2018, 132: 1093-1093. DOI: 10.1182/blood-2018-99-117504.
- History of Intracranial Hemorrhage Is Associated with In-Hospital Mortality in Ischemic Stroke Patients Treated with Intravenous ThrombolyticsSommaruga S, Chu S, Hwang D, Dearborn J, Sansing L, Cord B, Santarosa C, Samarth G, Petersen N, Gilmore E, Schindler J, Bijlenga P, Schaller K, Matouk C, Sheth K, Falcone G. History of Intracranial Hemorrhage Is Associated with In-Hospital Mortality in Ischemic Stroke Patients Treated with Intravenous Thrombolytics Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660745.
- Abstract WP203: Left Atrial Appendage Morphology is Similar in Embolic Stroke of Undetermined Source and Cardioembolic Stroke and Different From Atherothrombotic SubtypesYaghi S, Chang A, Hung P, Mac Grory B, Collins S, Gupta A, Reynolds J, Finn C, Hemendinger M, Cutting S, McTaggart R, Jayaraman M, Leasure A, Sansing L, Panda N, Song C, Chu A, Merkler A, Gialdini G, Sheth K, Kamel H, Elkind M, Greer D, Furie K, Atalay M. Abstract WP203: Left Atrial Appendage Morphology is Similar in Embolic Stroke of Undetermined Source and Cardioembolic Stroke and Different From Atherothrombotic Subtypes Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wp203.
- Abstract TMP14: Thrombolysis in Ischemic Stroke Patients with Prior History of Intracranial HemorrhageChu S, Sommaruga S, Hwang D, Dearborn J, Sansing L, Matouk C, Samarth G, Petersen N, Gilmore E, Schindler J, Sheth K, Falcone G. Abstract TMP14: Thrombolysis in Ischemic Stroke Patients with Prior History of Intracranial Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tmp14.
- Abstract TP304: Stroke-Specific Quality of Life as an Independent Outcome in Intracerebral HemorrhageLeasure A, Sreekrishnan A, Ormseth C, Miyares L, Mampre D, McLaughlin C, Amin H, Sansing L, Falcone G, Sheth K. Abstract TP304: Stroke-Specific Quality of Life as an Independent Outcome in Intracerebral Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tp304.
- Abstract TP331: Plasma IL-6 Levels are Independently Associated With Functional Outcome and Markers of Secondary Injury in Spontaneous Intracerebral HemorrhageLeasure A, Steinschneider A, Falcone G, Gilmore E, Sansing L, Sheth K. Abstract TP331: Plasma IL-6 Levels are Independently Associated With Functional Outcome and Markers of Secondary Injury in Spontaneous Intracerebral Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tp331.
- Abstract WMP101: Soluble St2 Predicts Functional Outcome After Spontaneous Intraparenchymal HemorrhageBevers M, Wolcott Z, Leasure A, Falcone G, Sansing L, Sheth K, Kimberly W. Abstract WMP101: Soluble St2 Predicts Functional Outcome After Spontaneous Intraparenchymal Hemorrhage Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wmp101.
- Abstract TP335: Divergent Responses of Macrophages and Microglia in the Hemorrhagic BrainChang C, Goods B, Askenase M, Love J, Sansing L. Abstract TP335: Divergent Responses of Macrophages and Microglia in the Hemorrhagic Brain Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tp335.
- Abstract TP338: Differences Between the Modified Rankin Scale and Barthel Index in Measuring Intracerebral Hemorrhage Recovery at 12 MonthsSreekrishnan A, Leasure A, Zhou S, Amin H, Petersen N, Hwang D, Schindler J, Gilmore E, Sansing L, Greer D, Sheth K. Abstract TP338: Differences Between the Modified Rankin Scale and Barthel Index in Measuring Intracerebral Hemorrhage Recovery at 12 Months Stroke 2017, 48 DOI: 10.1161/str.48.suppl_1.tp338.
- Abstract 213: Hematoma-infiltrating Macrophages Transition From Inflammatory to Reparative Programs in Patients After Intracerebral HemorrhageAskenase M, Goods B, Steinschneider A, Raddassi K, Beatty H, Hafler D, Love J, Sansing L. Abstract 213: Hematoma-infiltrating Macrophages Transition From Inflammatory to Reparative Programs in Patients After Intracerebral Hemorrhage Stroke 2017, 48 DOI: 10.1161/str.48.suppl_1.213.
- Abstract WMP105: Human Monocyte Derived Macrophage Phagocytize Eryptotic Erythrocytes in a Phosphotidylserine Dependent MechanismSteinschneider A, Chang C, Askenase M, Ai Y, Sansing L. Abstract WMP105: Human Monocyte Derived Macrophage Phagocytize Eryptotic Erythrocytes in a Phosphotidylserine Dependent Mechanism Stroke 2017, 48 DOI: 10.1161/str.48.suppl_1.wmp105.
- Abstract TP351: Axl/Mer Receptor Tyrosine Kinase Mediates Erythrophagocytosis-Induced Macrophage Reparative Phenotype and Brain Recovery in Experimental Intracerebral HemorrhageChang C, Thomas B, Askenase M, Steinschneider A, Ai Y, Taylor R, Rothlin C, Love C, Sansing L. Abstract TP351: Axl/Mer Receptor Tyrosine Kinase Mediates Erythrophagocytosis-Induced Macrophage Reparative Phenotype and Brain Recovery in Experimental Intracerebral Hemorrhage Stroke 2017, 48 DOI: 10.1161/str.48.suppl_1.tp351.
- Abstract TMP55: TGF-β1 Induces Microglial BDNF Production and Improves Functional Outcome After Intracerebral HemorrhageTaylor R, Ai Y, Sansing L. Abstract TMP55: TGF-β1 Induces Microglial BDNF Production and Improves Functional Outcome After Intracerebral Hemorrhage Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.tmp55.
- Abstract TP257: Apoptotic Erythrocytes Attenuate Macrophages Proinflammatory Phenotype in Intracerebral HemorrhageChang C, Taylor R, Steinschneider A, Ai Y, Sansing L. Abstract TP257: Apoptotic Erythrocytes Attenuate Macrophages Proinflammatory Phenotype in Intracerebral Hemorrhage Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.tp257.
- Inflammatory Mechanisms of Injury and Recovery after Intracerebral HemorrhageHammond M, Sansing L. Inflammatory Mechanisms of Injury and Recovery after Intracerebral Hemorrhage Current Immunology Reviews 2015, 11: 76-84. DOI: 10.2174/1573395511666150707181143.
- Abstract W MP49: Classifying M1/M2 Monocytes by JAK/STAT Activation After Murine Intracerebral HemorrhageHammond M, Lorenzo E, Taylor R, Ai Y, Sansing L. Abstract W MP49: Classifying M1/M2 Monocytes by JAK/STAT Activation After Murine Intracerebral Hemorrhage Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.wmp49.
- Abstract 114: CX3CR1-null Microglia Fail to Transition to an M2 Phenotype after Intracerebral HemorrhageTaylor R, Hammond M, Ai Y, Sansing L. Abstract 114: CX3CR1-null Microglia Fail to Transition to an M2 Phenotype after Intracerebral Hemorrhage Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.114.
- Hematoma clearance and functional recovery after intracerebral hemorrhage require recruited monocytesHammond M, Ai Y, Sansing L. Hematoma clearance and functional recovery after intracerebral hemorrhage require recruited monocytes Journal Of Neuroimmunology 2014, 275: 117. DOI: 10.1016/j.jneuroim.2014.08.311.
- Abstract T P237: Alpha-4 Integrin Mediates Inflammatory Monocyte Trafficking to the Brain After Intracerebral HemorrhageAmbler W, Hammond M, Taylor R, Sansing L, Ai Y. Abstract T P237: Alpha-4 Integrin Mediates Inflammatory Monocyte Trafficking to the Brain After Intracerebral Hemorrhage Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.tp237.
- Abstract T P238: Microglial CX3CR1 Required for M2 Polarization and Recovery After Intracerebral HemorrhageTaylor R, Hammond M, Ai Y, Sansing L. Abstract T P238: Microglial CX3CR1 Required for M2 Polarization and Recovery After Intracerebral Hemorrhage Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.tp238.
- Abstract W MP95: CCR2+ Monocytes Contribute to Hematoma Clearance After Experimental Intracerebral HemorrhageHammond M, Taylor R, Ai Y, Sansing L. Abstract W MP95: CCR2+ Monocytes Contribute to Hematoma Clearance After Experimental Intracerebral Hemorrhage Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wmp95.
- β-Blockers associated with no class-specific survival benefit in acute intracerebral hemorrhageShoup JP, Winkler J, Czap A, Staff I, Fortunato G, McCullough LD, Sansing LH. β-Blockers associated with no class-specific survival benefit in acute intracerebral hemorrhage Journal Of The Neurological Sciences 2013, 336: 127-131. PMID: 24183854, PMCID: PMC4956481, DOI: 10.1016/j.jns.2013.10.022.
- Abstract TP58: NIH Stroke Scale as Predictor of Prognosis in Posterior Circulation StrokeInoa V, Aron A, Staff I, Fortunato G, Sansing L. Abstract TP58: NIH Stroke Scale as Predictor of Prognosis in Posterior Circulation Stroke Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.atp58.
- Abstract 201: Changes In Inflammatory Response To Ischemic Stroke Across The Life SpanManwani B, Liu F, Sansing L, Kuchel G, McCullough L. Abstract 201: Changes In Inflammatory Response To Ischemic Stroke Across The Life Span Stroke 2012, 43 DOI: 10.1161/str.43.suppl_1.a201.
- Abstract 3720: Antiplatelet Medication and Bleeding Complications with External Ventricular DrainsWeinreb J, McLaughlin T, Yosufzai M, Sansing L, KURESHI I. Abstract 3720: Antiplatelet Medication and Bleeding Complications with External Ventricular Drains Stroke 2012, 43 DOI: 10.1161/str.43.suppl_1.a3720.
- Abstract 3867: Robust Infiltration of Inflammatory Monocytes 12 Hours After Experimental Intracerebral HemorrhageHammond M, Alander C, Sansing L. Abstract 3867: Robust Infiltration of Inflammatory Monocytes 12 Hours After Experimental Intracerebral Hemorrhage Stroke 2012, 43 DOI: 10.1161/str.43.suppl_1.a3867.
- Abstract 3822: Neutrophils and Toll-like receptor 4 Contribute to Injury after Intracerebral HemorhageSansing L, Harris T, Kasner S, Hunter C, Kariko K. Abstract 3822: Neutrophils and Toll-like receptor 4 Contribute to Injury after Intracerebral Hemorhage Stroke 2012, 43 DOI: 10.1161/str.43.suppl_1.a3822.
- Abstract 3940: Perihematomal Leukocytes Peak 3 Days After Intracerebral HemorrhageHammond M, Alander C, Sansing L. Abstract 3940: Perihematomal Leukocytes Peak 3 Days After Intracerebral Hemorrhage Stroke 2012, 43 DOI: 10.1161/str.43.suppl_1.a3940.
- Abstract 3452: Antiphosphatidylserine-prothrombin Antibodies Are Associated With Outcome After TIAMullen M, Messe S, Kasner S, Sansing L, Husain M, Norman G, Shums Z, McIntire C, Cucchiara B. Abstract 3452: Antiphosphatidylserine-prothrombin Antibodies Are Associated With Outcome After TIA Stroke 2012, 43 DOI: 10.1161/str.43.suppl_1.a3452.
- Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in MiceSansing L, Kasner S, McCullough L, Agarwal P, Welsh F, Kariko K. Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice Journal Of Visualized Experiments 2011 DOI: 10.3791/2618-v.
- Anti-Adrenergic Medications and Edema Development after Intracerebral HemorrhageSansing LH, Messe SR, Cucchiara BL, Lyden PD, Kasner SE. Anti-Adrenergic Medications and Edema Development after Intracerebral Hemorrhage Neurocritical Care 2011, 14: 395-400. PMID: 21264527, DOI: 10.1007/s12028-010-9498-z.
- PRIOR ANTIPLATELET USE DOES NOT AFFECT HEMORRHAGE GROWTH OR OUTCOME AFTER ICH 2Naidech A, Bernstein R, Alberts M, Bleck T, Sansing L, Cucchiara B, Messe S, Lyden P, Kasner S. PRIOR ANTIPLATELET USE DOES NOT AFFECT HEMORRHAGE GROWTH OR OUTCOME AFTER ICH 2 Neurology 2010, 74: 526-527. PMID: 20142623, DOI: 10.1212/wnl.0b013e3181c778be.
- Who will participate in acute stroke trials?Kasner SE, Del Giudice A, Rosenberg S, Sheen M, Luciano JM, Cucchiara BL, Messé SR, Sansing LH, Baren JM. Who will participate in acute stroke trials? Neurology 2009, 72: 1682-1688. PMID: 19433742, PMCID: PMC2683644, DOI: 10.1212/wnl.0b013e3181a55fbe.
- Prior antiplatelet use does not affect hemorrhage growth or outcome after ICHSYMBOLSansing LH, Messe SR, Cucchiara BL, Cohen SN, Lyden PD, Kasner SE. Prior antiplatelet use does not affect hemorrhage growth or outcome after ICHSYMBOL Neurology 2009, 72: 1397-1402. PMID: 19129506, PMCID: PMC2677505, DOI: 10.1212/01.wnl.0000342709.31341.88.
- Encephalopathy and peripheral neuropathy following diethylene glycol ingestionHasbani MJ, Sansing LH, Perrone J, Asbury AK, Bird SJ. Encephalopathy and peripheral neuropathy following diethylene glycol ingestion Neurology 2005, 64: 1273-1275. PMID: 15824363, DOI: 10.1212/01.wnl.0000156804.07265.1a.
- Willisian collateralizationPuglia P, Liebeskind D, Sansing L. Willisian collateralization Neurology 2005, 64: 767. PMID: 15728325, DOI: 10.1212/wnl.64.4.767.
Clinical Trials
Conditions | Study Title |
---|---|
Diseases of the Nervous System | Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis (CAPTIVA) |
Diseases of the Cardiovascular System | Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH) |
Diseases of the Nervous System; Hypertension | Regulating Blood Pressure During Recovery from Intracerebral Hemorrhage (REDUCE) |
Diseases of the Cardiovascular System; Diseases of the Nervous System | Anticoagulation for Stroke Prevention and Recovery After ICH (ASPIRE) |
Diseases of the Nervous System | Transforming Acute Stroke Detection through Real Time Neurological Monitoring |