Caroline Zeiss, DACVP, DACLAM

• Alessandro Santin
• Clemens Bergwitz
• Dana Dunne
• Erol Fikrig
• Gerald I Shulman
• Heather Allore
• Josephine Hoh
• Masoud Azodi
• Mehran M Sadeghi
• Susan Compton
• TuKiet Lam
• Valerie Horsley

Animal Diseases; Neuroanatomy; Neurobiology; Ophthalmology; Pathologic Processes; Primates; Neurodegenerative Diseases; Informatics; Translational Research, Biomedical

• Modeling pandemic to endemic patterns of SARS-CoV-2 transmission using parameters estimated from animal model dataMullin S, Wyk BV, Asher JL, Compton SR, Allore HG, Zeiss CJ. Modeling pandemic to endemic patterns of SARS-CoV-2 transmission using parameters estimated from animal model data. PNAS Nexus 2022, 1: pgac096. PMID: 35799833, PMCID: PMC9254158, DOI: 10.1093/pnasnexus/pgac096.
• Modeling SARS-CoV-2 propagation using rat coronavirus-associated shedding and transmissionZeiss CJ, Asher JL, Wyk B, Allore HG, Compton SR. Modeling SARS-CoV-2 propagation using rat coronavirus-associated shedding and transmission. PLOS ONE 2021, 16: e0260038. PMID: 34813610, PMCID: PMC8610237, DOI: 10.1371/journal.pone.0260038.
• Simple, Single-Shot Phosphoproteomic Analysis of Heat-Stable Tau Identifies Age-Related Changes in pS235- and pS396-Tau Levels in Non-human PrimatesLeslie SN, Kanyo J, Datta D, Wilson RS, Zeiss C, Duque A, Lam TT, Arnsten AFT, Nairn AC. Simple, Single-Shot Phosphoproteomic Analysis of Heat-Stable Tau Identifies Age-Related Changes in pS235- and pS396-Tau Levels in Non-human Primates. Frontiers In Aging Neuroscience 2021, 13: 767322. PMID: 34867294, PMCID: PMC8637411, DOI: 10.3389/fnagi.2021.767322.
• Comparative Milestones in Rodent and Human Postnatal Central Nervous System DevelopmentZeiss CJ. Comparative Milestones in Rodent and Human Postnatal Central Nervous System Development. Toxicologic Pathology 2021, 49: 1368-1373. PMID: 34569375, DOI: 10.1177/01926233211046933.
• DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse modelPaluri SL, Burak M, Senejani AG, Levinson M, Rahim T, Clairmont K, Kashgarian M, Alvarado-Cruz I, Meas R, Cardó-Vila M, Zeiss C, Maher S, Bothwell ALM, Coskun E, Kant M, Jaruga P, Dizdaroglu M, Lloyd R, Sweasy JB. DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model. DNA Repair 2021, 105: 103152. PMID: 34186496, PMCID: PMC8635285, DOI: 10.1016/j.dnarep.2021.103152.
• Animal Models of COVID-19 II. Comparative ImmunologyVeenhuis RT, Zeiss CJ. Animal Models of COVID-19 II. Comparative Immunology. ILAR Journal 2021, 62: ilab010-. PMID: 33914873, PMCID: PMC8135340, DOI: 10.1093/ilar/ilab010.
• Animal Models of COVID-19. I. Comparative Virology and Disease PathogenesisZeiss CJ, Compton S, Veenhuis RT. Animal Models of COVID-19. I. Comparative Virology and Disease Pathogenesis. ILAR Journal 2021, 62: ilab007-. PMID: 33836527, PMCID: PMC8083356, DOI: 10.1093/ilar/ilab007.
• Age‐related calcium dysregulation linked with tau pathology and impaired cognition in non‐human primatesDatta D, Leslie SN, Wang M, Morozov YM, Yang S, Mentone S, Zeiss C, Duque A, Rakic P, Horvath TL, van Dyck C, Nairn AC, Arnsten AFT. Age‐related calcium dysregulation linked with tau pathology and impaired cognition in non‐human primates. Alzheimer's & Dementia 2021, 17: 920-932. PMID: 33829643, PMCID: PMC8195842, DOI: 10.1002/alz.12325.
• Dual Angiotensin Receptor-Neprilysin Inhibition With Sacubitril/Valsartan Attenuates Systolic Dysfunction in Experimental Doxorubicin-Induced CardiotoxicityBoutagy NE, Feher A, Pfau D, Liu Z, Guerrera NM, Freeburg LA, Womack SJ, Hoenes AC, Zeiss C, Young LH, Spinale FG, Sinusas AJ. Dual Angiotensin Receptor-Neprilysin Inhibition With Sacubitril/Valsartan Attenuates Systolic Dysfunction in Experimental Doxorubicin-Induced Cardiotoxicity. JACC CardioOncology 2020, 2: 774-787. PMID: 33437965, PMCID: PMC7799406, DOI: 10.1016/j.jaccao.2020.09.007.
• AgRP neurons control compulsive exercise and survival in an activity-based anorexia modelMiletta MC, Iyilikci O, Shanabrough M, Šestan-Peša M, Cammisa A, Zeiss CJ, Dietrich MO, Horvath TL. AgRP neurons control compulsive exercise and survival in an activity-based anorexia model. Nature Metabolism 2020, 2: 1204-1211. PMID: 33106687, DOI: 10.1038/s42255-020-00300-8.
• Utility of spontaneous animal models of Alzheimer’s disease in preclinical efficacy studiesZeiss CJ. Utility of spontaneous animal models of Alzheimer’s disease in preclinical efficacy studies. Cell And Tissue Research 2020, 380: 273-286. PMID: 32337614, DOI: 10.1007/s00441-020-03198-6.
• Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal myofiber function and survivalChande S, Caballero D, Ho BB, Fetene J, Serna J, Pesta D, Nasiri A, Jurczak M, Chavkin NW, Hernando N, Giachelli CM, Wagner CA, Zeiss C, Shulman GI, Bergwitz C. Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal myofiber function and survival. Scientific Reports 2020, 10: 3069. PMID: 32080237, PMCID: PMC7033257, DOI: 10.1038/s41598-020-59430-4.
• Menagerie: A text-mining tool to support animal-human translation in neurodegeneration researchZeiss CJ, Shin D, Wyk B, Beck AP, Zatz N, Sneiderman CA, Kilicoglu H. Menagerie: A text-mining tool to support animal-human translation in neurodegeneration research. PLOS ONE 2019, 14: e0226176. PMID: 31846471, PMCID: PMC6917268, DOI: 10.1371/journal.pone.0226176.
• Genetic deficiency or pharmacological inhibition of miR-33 protects from kidney fibrosisPrice NL, Miguel V, Ding W, Singh AK, Malik S, Rotllan N, Moshnikova A, Toczek J, Zeiss C, Sadeghi MM, Arias N, Baldán Á, Andreev OA, Rodríguez-Puyol D, Bahal R, Reshetnyak YK, Suárez Y, Fernández-Hernando C, Lamas S. Genetic deficiency or pharmacological inhibition of miR-33 protects from kidney fibrosis. JCI Insight 2019, 4 PMID: 31613798, PMCID: PMC6948871, DOI: 10.1172/jci.insight.131102.
• Doxorubicin-Induced Cardiotoxicity in Collaborative Cross (CC) Mice Recapitulates Individual Cardiotoxicity in HumansZeiss CJ, Gatti DM, Toro-Salazar O, Davis C, Lutz CM, Spinale F, Stearns T, Furtado MB, Churchill GA. Doxorubicin-Induced Cardiotoxicity in Collaborative Cross (CC) Mice Recapitulates Individual Cardiotoxicity in Humans. G3: Genes, Genomes, Genetics 2019, 9: 2637-2646. PMID: 31263061, PMCID: PMC6686936, DOI: 10.1534/g3.119.400232.
• An ABCA4 loss-of-function mutation causes a canine form of Stargardt diseaseMäkeläinen S, Gòdia M, Hellsand M, Viluma A, Hahn D, Makdoumi K, Zeiss CJ, Mellersh C, Ricketts SL, Narfström K, Hallböök F, Ekesten B, Andersson G, Bergström TF. An ABCA4 loss-of-function mutation causes a canine form of Stargardt disease. PLOS Genetics 2019, 15: e1007873. PMID: 30889179, PMCID: PMC6424408, DOI: 10.1371/journal.pgen.1007873.
• Investigating the role of interleukin-1 beta and glutamate in inflammatory bowel disease and epilepsy using discovery browsingRindflesch TC, Blake CL, Cairelli MJ, Fiszman M, Zeiss CJ, Kilicoglu H. Investigating the role of interleukin-1 beta and glutamate in inflammatory bowel disease and epilepsy using discovery browsing. Journal Of Biomedical Semantics 2018, 9: 25. PMID: 30587224, PMCID: PMC6307110, DOI: 10.1186/s13326-018-0192-y.
• Pathology Study Design, Conduct, and Reporting to Achieve Rigor and Reproducibility in Translational Research Using Animal Models.Everitt JI, Treuting PM, Scudamore C, Sellers R, Turner PV, Ward JM, Zeiss CJ. Pathology Study Design, Conduct, and Reporting to Achieve Rigor and Reproducibility in Translational Research Using Animal Models. ILAR Journal 2018, 59: 4-12. PMID: 30624739, DOI: 10.1093/ilar/ily020.
• Use of integrated imaging and serum biomarker profiles to identify subclinical dysfunction in pediatric cancer patients treated with anthracyclinesToro-Salazar OH, Lee JH, Zellars KN, Perreault PE, Mason KC, Wang Z, Hor KN, Gillan E, Zeiss CJ, Gatti DM, Davey BT, Kutty S, Liang BT, Spinale FG. Use of integrated imaging and serum biomarker profiles to identify subclinical dysfunction in pediatric cancer patients treated with anthracyclines. Cardio-Oncology 2018, 4: 4. PMID: 29900007, PMCID: PMC5995570, DOI: 10.1186/s40959-018-0030-5.
• Immune responses to the real worldZeiss CJ, Brayton CF. Immune responses to the real world. Lab Animal 2017, 47: 13-14. PMID: 29297473, DOI: 10.1038/laban.1384.
• Safety and Efficacy of AAV5 Vectors Expressing Human or Canine CNGB3 in CNGB3-Mutant DogsYe GJ, Komáromy AM, Zeiss C, Calcedo R, Harman CD, Koehl KL, Stewart GA, Iwabe S, Chiodo VA, Hauswirth WW, Aguirre GD, Chulay JD. Safety and Efficacy of AAV5 Vectors Expressing Human or Canine CNGB3 in CNGB3-Mutant Dogs. Human Gene Therapy 2017, 28: 197-207. PMID: 29020838, PMCID: PMC5733651, DOI: 10.1089/humc.2017.125.
• Informatics Support for Basic Research in Biomedicine.Rindflesch TC, Blake CL, Fiszman M, Kilicoglu H, Rosemblat G, Schneider J, Zeiss CJ. Informatics Support for Basic Research in Biomedicine. ILAR Journal 2017, 58: 80-89. PMID: 28838071, PMCID: PMC5886329, DOI: 10.1093/ilar/ilx004.
• Bridging the Gap between Reproducibility and Translation: Data Resources and Approaches.Zeiss CJ, Johnson LK. Bridging the Gap between Reproducibility and Translation: Data Resources and Approaches. ILAR Journal 2017, 58: 1-3. PMID: 28586416, DOI: 10.1093/ilar/ilx017.
• From Reproducibility to Translation in Neurodegenerative Disease.Zeiss CJ. From Reproducibility to Translation in Neurodegenerative Disease. ILAR Journal 2017, 58: 106-114. PMID: 28444192, DOI: 10.1093/ilar/ilx006.
• Established patterns of animal study design undermine translation of disease-modifying therapies for Parkinson’s diseaseZeiss CJ, Allore HG, Beck AP. Established patterns of animal study design undermine translation of disease-modifying therapies for Parkinson’s disease. PLOS ONE 2017, 12: e0171790. PMID: 28182759, PMCID: PMC5300282, DOI: 10.1371/journal.pone.0171790.
• Expression of the CTCFL Gene during Mouse Embryogenesis Causes Growth Retardation, Postnatal Lethality, and Dysregulation of the Transforming Growth Factor β PathwaySati L, Zeiss C, Yekkala K, Demir R, McGrath J. Expression of the CTCFL Gene during Mouse Embryogenesis Causes Growth Retardation, Postnatal Lethality, and Dysregulation of the Transforming Growth Factor β Pathway. Molecular And Cellular Biology 2015, 35: 3436-3445. PMID: 26169830, PMCID: PMC4561735, DOI: 10.1128/mcb.00381-15.
• Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesisGoldstein J, Roth E, Roberts N, Zwick R, Lin S, Fletcher S, Tadeu A, Wu C, Beck A, Zeiss C, Suárez-Fariñas M, Horsley V. Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis. Molecular Biology Of The Cell 2015, 26: 3606-3614. PMID: 26310443, PMCID: PMC4603931, DOI: 10.1091/mbc.e15-05-0282.
• Clostridium perfringens enterotoxin C‐terminal domain labeled to fluorescent dyes for in vivo visualization of micrometastatic chemotherapy‐resistant ovarian cancerCocco E, Shapiro EM, Gasparrini S, Lopez S, Schwab CL, Bellone S, Bortolomai I, Sumi NJ, Bonazzoli E, Nicoletti R, Deng Y, Saltzman WM, Zeiss CJ, Centritto F, Black JD, Silasi DA, Ratner E, Azodi M, Rutherford TJ, Schwartz PE, Pecorelli S, Santin AD. Clostridium perfringens enterotoxin C‐terminal domain labeled to fluorescent dyes for in vivo visualization of micrometastatic chemotherapy‐resistant ovarian cancer. International Journal Of Cancer 2015, 137: 2618-2629. PMID: 26060989, PMCID: PMC4573336, DOI: 10.1002/ijc.29632.
• Improving the predictive value of interventional animal models dataZeiss CJ. Improving the predictive value of interventional animal models data. Drug Discovery Today 2014, 20: 475-482. PMID: 25448761, PMCID: PMC4417064, DOI: 10.1016/j.drudis.2014.10.015.
• Preclinical Safety Evaluation of a Recombinant AAV8 Vector for X-Linked Retinoschisis After Intravitreal Administration in RabbitsMarangoni D, Wu Z, Wiley HE, Zeiss CJ, Vijayasarathy C, Zeng Y, Hiriyanna S, Bush RA, Wei LL, Colosi P, Sieving PA. Preclinical Safety Evaluation of a Recombinant AAV8 Vector for X-Linked Retinoschisis After Intravitreal Administration in Rabbits. Human Gene Therapy 2014, 25: 202-211. PMID: 25211193, PMCID: PMC4275775, DOI: 10.1089/humc.2014.067.
• Hypothalamic prolyl endopeptidase (PREP) regulates pancreatic insulin and glucagon secretion in miceKim JD, Toda C, D’Agostino G, Zeiss CJ, DiLeone RJ, Elsworth JD, Kibbey RG, Chan O, Harvey BK, Richie CT, Savolainen M, Myöhänen T, Jeong JK, Diano S. Hypothalamic prolyl endopeptidase (PREP) regulates pancreatic insulin and glucagon secretion in mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 11876-11881. PMID: 25071172, PMCID: PMC4136568, DOI: 10.1073/pnas.1406000111.
• Mutation of POLB Causes Lupus in MiceSenejani AG, Liu Y, Kidane D, Maher SE, Zeiss CJ, Park HJ, Kashgarian M, McNiff JM, Zelterman D, Bothwell AL, Sweasy JB. Mutation of POLB Causes Lupus in Mice. Cell Reports 2014, 6: 1-8. PMID: 24388753, PMCID: PMC3916967, DOI: 10.1016/j.celrep.2013.12.017.
• MyD88 Deficiency Markedly Worsens Tissue Inflammation and Bacterial Clearance in Mice Infected with Treponema pallidum, the Agent of SyphilisSilver AC, Dunne DW, Zeiss CJ, Bockenstedt LK, Radolf JD, Salazar JC, Fikrig E. MyD88 Deficiency Markedly Worsens Tissue Inflammation and Bacterial Clearance in Mice Infected with Treponema pallidum, the Agent of Syphilis. PLOS ONE 2013, 8: e71388. PMID: 23940747, PMCID: PMC3734110, DOI: 10.1371/journal.pone.0071388.
• Translational models of ocular diseaseZeiss CJ. Translational models of ocular disease. Veterinary Ophthalmology 2013, 16: 15-33. PMID: 23750503, DOI: 10.1111/vop.12065.
• Fungal polymerase chain reaction testing in equine ulcerative keratitisZeiss C, Neaderland M, Yang F, Terwilliger G, Compton S. Fungal polymerase chain reaction testing in equine ulcerative keratitis. Veterinary Ophthalmology 2012, 16: 341-351. PMID: 23227970, DOI: 10.1111/vop.12004.
• Poliomyelitis in MuLV-infected ICR-SCID mice after injection of basement membrane matrix contaminated with lactate dehydrogenase-elevating virus.Carlson Scholz JA, Garg R, Compton SR, Allore HG, Zeiss CJ, Uchio EM. Poliomyelitis in MuLV-infected ICR-SCID mice after injection of basement membrane matrix contaminated with lactate dehydrogenase-elevating virus. Comparative Medicine 2011, 61: 404-11. PMID: 22330347, PMCID: PMC3193062.
• Designing Phenotyping Studies for Genetically Engineered MiceZeiss CJ, Ward JM, Allore HG. Designing Phenotyping Studies for Genetically Engineered Mice. Veterinary Pathology 2011, 49: 24-31. PMID: 21930803, PMCID: PMC3957214, DOI: 10.1177/0300985811417247.
• A slowly progressive retinopathy in the Shetland SheepdogKarlstam L, Hertil E, Zeiss C, Ropstad EO, Bjerkås E, Dubielzig RR, Ekesten B. A slowly progressive retinopathy in the Shetland Sheepdog. Veterinary Ophthalmology 2011, 14: 227-238. PMID: 21733063, DOI: 10.1111/j.1463-5224.2010.00866.x.
• Maropitant citrate for treatment of ulcerative dermatitis in mice with a C57BL/6 background.Williams-Fritze MJ, Carlson Scholz JA, Zeiss C, Deng Y, Wilson SR, Franklin R, Smith PC. Maropitant citrate for treatment of ulcerative dermatitis in mice with a C57BL/6 background. Journal Of The American Association For Laboratory Animal Science 2011, 50: 221-6. PMID: 21439216, PMCID: PMC3061423.
• REVIEW PAPER: Animals as Models of Age-Related Macular DegenerationZeiss CJ. REVIEW PAPER: Animals as Models of Age-Related Macular Degeneration. Veterinary Pathology 2010, 47: 396-413. PMID: 20382825, DOI: 10.1177/0300985809359598.
• Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in miceChen H, Ko G, Zatti A, Di Giacomo G, Liu L, Raiteri E, Perucco E, Collesi C, Min W, Zeiss C, De Camilli P, Cremona O. Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 2009, 106: 13838-13843. PMID: 19666558, PMCID: PMC2728981, DOI: 10.1073/pnas.0907008106.
• CREB1/ATF1 Activation in Photoreceptor Degeneration and ProtectionBeltran WA, Allore HG, Johnson E, Towle V, Tao W, Acland GM, Aguirre GD, Zeiss CJ. CREB1/ATF1 Activation in Photoreceptor Degeneration and Protection. Investigative Ophthalmology & Visual Science 2009, 50: 5355-5363. PMID: 19643965, PMCID: PMC3172238, DOI: 10.1167/iovs.09-3741.
• Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALSWang J, Farr GW, Zeiss CJ, Rodriguez-Gil DJ, Wilson JH, Furtak K, Rutkowski DT, Kaufman RJ, Ruse CI, Yates JR, Perrin S, Feany MB, Horwich AL. Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS. Proceedings Of The National Academy Of Sciences Of The United States Of America 2009, 106: 1392-1397. PMID: 19171884, PMCID: PMC2631083, DOI: 10.1073/pnas.0813045106.
• Enhanced Ovarian Cancer Tumorigenesis and Metastasis by the Macrophage Colony-Stimulating FactorToy EP, Azodi M, Folk NL, Zito CM, Zeiss CJ, Chambers SK. Enhanced Ovarian Cancer Tumorigenesis and Metastasis by the Macrophage Colony-Stimulating Factor. Neoplasia 2009, 11: 136-144. PMID: 19177198, PMCID: PMC2631138, DOI: 10.1593/neo.81150.
• Reversal of Blindness in Animal Models of Leber Congenital Amaurosis Using Optimized AAV2-mediated Gene TransferBennicelli J, Wright JF, Komaromy A, Jacobs JB, Hauck B, Zelenaia O, Mingozzi F, Hui D, Chung D, Rex TS, Wei Z, Qu G, Zhou S, Zeiss C, Arruda VR, Acland GM, Dell'Osso LF, High KA, Maguire AM, Bennett J. Reversal of Blindness in Animal Models of Leber Congenital Amaurosis Using Optimized AAV2-mediated Gene Transfer. Molecular Therapy 2008, 16: 458-465. PMID: 18209734, PMCID: PMC2842085, DOI: 10.1038/sj.mt.6300389.
• Motor deficits and altered striatal gene expression in aphakia (ak) miceSingh B, Wilson JH, Vasavada HH, Guo Z, Allore HG, Zeiss CJ. Motor deficits and altered striatal gene expression in aphakia (ak) mice. Brain Research 2007, 1185: 283-292. PMID: 17949697, PMCID: PMC3904435, DOI: 10.1016/j.brainres.2007.09.006.
• Safety in Nonhuman Primates of Ocular AAV2-RPE65, a Candidate Treatment for Blindness in Leber Congenital AmaurosisJacobson SG, Boye SL, Aleman TS, Conlon TJ, Zeiss CJ, Roman AJ, Cideciyan AV, Schwartz SB, Komaromy AM, Doobrajh M, Cheung AY, Sumaroka A, Pearce-Kelling SE, Aguirre GD, Kaushal S, Maguire AM, Flotte TR, Hauswirth WW. Safety in Nonhuman Primates of Ocular AAV2-RPE65, a Candidate Treatment for Blindness in Leber Congenital Amaurosis. Human Gene Therapy 2006, 17: 845-858. PMID: 16942444, DOI: 10.1089/hum.2006.17.845.
• Safety of Recombinant Adeno-Associated Virus Type 2–RPE65 Vector Delivered by Ocular Subretinal InjectionJacobson SG, Acland GM, Aguirre GD, Aleman TS, Schwartz SB, Cideciyan AV, Zeiss CJ, Komaromy AM, Kaushal S, Roman AJ, Windsor EA, Sumaroka A, Pearce-Kelling SE, Conlon TJ, Chiodo VA, Boye SL, Flotte TR, Maguire AM, Bennett J, Hauswirth WW. Safety of Recombinant Adeno-Associated Virus Type 2–RPE65 Vector Delivered by Ocular Subretinal Injection. Molecular Therapy 2006, 13: 1074-1084. PMID: 16644289, DOI: 10.1016/j.ymthe.2006.03.005.
• Neuroanatomical Phenotyping in the Mouse: The Dopaminergic SystemZeiss CJ. Neuroanatomical Phenotyping in the Mouse: The Dopaminergic System. Veterinary Pathology 2005, 42: 753-773. PMID: 16301571, DOI: 10.1354/vp.42-6-753.
• CNTF induces dose-dependent alterations in retinal morphology in normal and rcd-1 canine retinaZeiss CJ, Allore HG, Towle V, Tao W. CNTF induces dose-dependent alterations in retinal morphology in normal and rcd-1 canine retina. Experimental Eye Research 2005, 82: 395-404. PMID: 16143329, DOI: 10.1016/j.exer.2005.07.014.
• Complement Factor H Polymorphism in Age-Related Macular DegenerationKlein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferris FL, Ott J, Barnstable C, Hoh J. Complement Factor H Polymorphism in Age-Related Macular Degeneration. Science 2005, 308: 385-389. PMID: 15761122, PMCID: PMC1512523, DOI: 10.1126/science.1109557.
• Correlation of tumor phenotype with c-fms proto-oncogene expression in an in vivo intraperitoneal model for experimental human breast cancer metastasisToy EP, Bonafé N, Savlu A, Zeiss C, Zheng W, Flick M, Chambers SK. Correlation of tumor phenotype with c-fms proto-oncogene expression in an in vivo intraperitoneal model for experimental human breast cancer metastasis. Clinical & Experimental Metastasis 2005, 22: 1-9. PMID: 16132573, DOI: 10.1007/s10585-005-0718-4.
• A null mutation of Hhex results in abnormal cardiac development,defective vasculogenesis and elevated Vegfa levelsHallaq H, Pinter E, Enciso J, McGrath J, Zeiss C, Brueckner M, Madri J, Jacobs HC, Wilson CM, Vasavada H, Jiang X, Bogue CW. A null mutation of Hhex results in abnormal cardiac development,defective vasculogenesis and elevated Vegfa levels. Development 2004, 131: 5197-5209. PMID: 15459110, DOI: 10.1242/dev.01393.
• A morphologic study of intravitreal membranes associated with intraocular hemorrhage in the dogZeiss CJ, Dubielzig RR. A morphologic study of intravitreal membranes associated with intraocular hemorrhage in the dog. Veterinary Ophthalmology 2004, 7: 239-243. PMID: 15200620, DOI: 10.1111/j.1463-5224.2004.04033.x.
• Proliferation of Microglia, but not Photoreceptors, in the Outer Nuclear Layer of the rd-1 MouseZeiss CJ, Johnson EA. Proliferation of Microglia, but not Photoreceptors, in the Outer Nuclear Layer of the rd-1 Mouse. Investigative Ophthalmology & Visual Science 2004, 45: 971-976. PMID: 14985319, DOI: 10.1167/iovs.03-0301.
• Caspase-3 in Postnatal Retinal Development and DegenerationZeiss CJ, Neal J, Johnson EA. Caspase-3 in Postnatal Retinal Development and Degeneration. Investigative Ophthalmology & Visual Science 2004, 45: 964-970. PMID: 14985318, DOI: 10.1167/iovs.03-0439.
• The Apoptosis-Necrosis Continuum: Insights from Genetically Altered MiceZeiss CJ. The Apoptosis-Necrosis Continuum: Insights from Genetically Altered Mice. Veterinary Pathology 2003, 40: 481-495. PMID: 12949404, DOI: 10.1354/vp.40-5-481.
• Feline Intraocular Tumors May Arise from Transformation of Lens EpitheliumZeiss CJ, Johnson EM, Dubielzig RR. Feline Intraocular Tumors May Arise from Transformation of Lens Epithelium. Veterinary Pathology 2003, 40: 355-362. PMID: 12824506, DOI: 10.1354/vp.40-4-355.
• Pathogenesis of mouse hepatitis virus infection in gamma interferon-deficient mice is modulated by co-infection with Helicobacter hepaticus.Compton SR, Ball-Goodrich LJ, Zeiss CJ, Johnson LK, Johnson EA, Macy JD. Pathogenesis of mouse hepatitis virus infection in gamma interferon-deficient mice is modulated by co-infection with Helicobacter hepaticus. Comparative Medicine 2003, 53: 197-206. PMID: 12784855.
• Mutant mouse pathology: an exercise in integration.Zeiss CJ. Mutant mouse pathology: an exercise in integration. Lab Animal 2002, 31: 34-9. PMID: 11910406, DOI: 10.1038/5000124.