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A new Yale study found that the liver plays a major role in regulating feeding behavior in mice, a discovery that could have implications for people with eating disorders and metabolic diseases. The study, which was done in collaboration with colleagues in Germany, also adds to a growing body of evidence that shows the most advanced part of the brain, the cerebral cortex, is affected by the rest of the body, not just the other way around.
- June 14, 2022Source: NBC Connecticut
Yale researchers think they could study human psychiatric illness in plants and they hope it’ll be used in a more mainstream way.
- June 02, 2022Source: YaleNews
What if scientists could study human psychiatric illness in plants? Yale researchers think it’s possible and they’ve taken an important first step. In a study published June 2 in Cellular and Molecular Life Sciences, they investigated a gene very similar in both plants and mammals and looked at how it affects behavior in each.
- April 11, 2022Source: Yale News
Yale scientists have discovered that a protein known as augmentor-alpha can regulate body weight, an insight that may lead to new treatments for metabolic disorders.
- April 07, 2022Source: University of Oxford Department of Physiology, Anatomy and Genetics (DPAG)
The Oxford Book Launch 'Body Brain Behavior - The Need For Conversations' brought together three world leading scientist authors, Professor Zoltán Molnár and Yale Professors Tamas Horvath and Joy Hirsch, with Oxford's neuroscience community on Thursday 7 April 2022.
- February 01, 2022Source: YaleNews
For a new book, two Yale researchers and a colleague from Oxford take a novel approach to explore the interrelated complexities of the brain: They talk it out. In “Body, Brain, Behavior: Three Views and a Conversation,” co-authored by Tamas Horvath and Joy Hirsch of the Yale School of Medicine, and Zoltán Molnár, a professor of developmental neuroscience at the University of Oxford, the three researchers each share a traditional chapter related to their disciplines: endocrine physiology, social neuroscience, and developmental neuroscience. But connecting the chapters is a series of transcripts of weekly conversations they held over two years.
- November 10, 2021Source: North American Vascular Biology Organization
The NAVBO Meritorious Awards Committee, the Scientific Advisory Board, and the NAVBO Council announce with pleasure the selection of Carlos Fernández-Hernando, PhD, as the recipient of the 2021 Judah Folkman Award in Vascular Biology. This award recognizes outstanding contributions from vascular biologists who are at mid-career (within fifteen years of their first faculty appointment).
- September 01, 2021Source: YaleNews
With age, people become more susceptible to cold as inflammation and metabolic problems which can lead to a host of chronic diseases. Researchers at Yale and the University of California-San Francisco have found one culprit in this process — the same immune cells within fat that are designed to protect us from cold temperatures.
- January 10, 2020
In obese individuals, cellular "doormen" open the gates far too wide in certain key fat cells, known as visceral fat cells, letting in too many carbohydrates without first burning off lipids. This leads to a ballooning of the size of visceral fat cells in the belly.
- January 10, 2020Source: Nature Communications
Abstract Excessive visceral fat accumulation is a primary risk factor for metabolically unhealthy obesity and related diseases. The visceral fat is highly susceptible to the availability of external nutrients. Moreover, adipose OGT overexpression inhibits lipolysis and promotes diet-induced obesity. These findings establish an essential role for OGT in adipose tissue homeostasis and indicate a unique potential for targeting O-GlcNAc signaling in the treatment of obesity.