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Highly Cited Researchers from Yale

The Linda Lorimer Award for Distinguished Service honors staff members whose work supports and furthers Yale’s achievement of its core mission. Comparative Medicine’s congratulations to Marya Shanabrough, Research Associate for her consistent exemplary leadership and excellence of work.

An enzyme found in the brain acts as a major regulator of body weight, Yale researchers have discovered. In a new study, they found that removing the enzyme from neurons in a part of the brain known as the hypothalamus led mice to gain weight and burn less fat. This finding, they say, suggests that the enzyme could be a target for treating metabolic disease.

A new Yale study found that the liver plays a major role in regulating feeding behavior in mice, a discovery that could have implications for people with eating disorders and metabolic diseases. The study, which was done in collaboration with colleagues in Germany, also adds to a growing body of evidence that shows the most advanced part of the brain, the cerebral cortex, is affected by the rest of the body, not just the other way around.

What if scientists could study human psychiatric illness in plants? Yale researchers think it’s possible and they’ve taken an important first step. In a study published June 2 in Cellular and Molecular Life Sciences, they investigated a gene very similar in both plants and mammals and looked at how it affects behavior in each.

Yale scientists have discovered that a protein known as augmentor-alpha can regulate body weight, an insight that may lead to new treatments for metabolic disorders.

The Oxford Book Launch 'Body Brain Behavior - The Need For Conversations' brought together three world leading scientist authors, Professor Zoltán Molnár and Yale Professors Tamas Horvath and Joy Hirsch, with Oxford's neuroscience community on Thursday 7 April 2022.

For a new book, two Yale researchers and a colleague from Oxford take a novel approach to explore the interrelated complexities of the brain: They talk it out. In “Body, Brain, Behavior: Three Views and a Conversation,” co-authored by Tamas Horvath and Joy Hirsch of the Yale School of Medicine, and Zoltán Molnár, a professor of developmental neuroscience at the University of Oxford, the three researchers each share a traditional chapter related to their disciplines: endocrine physiology, social neuroscience, and developmental neuroscience. But connecting the chapters is a series of transcripts of weekly conversations they held over two years.