Marc Schneeberger Pane, PhD
Assistant Professor in Cellular and Molecular PhysiologyCards
Appointments
Contact Info
Cellular & Molecular Physiology
333 Cedar Street, B-Wing, E Level
New Haven, Connecticut 06510
United States
About
Titles
Assistant Professor in Cellular and Molecular Physiology
Biography
Marc Schneeberger Pané received his B.S. in Pharmacy from Barcelona University, Catalonia in 2010. Next, he received his M.S. in Biomedicine from Barcelona University, Catalonia in 2011. He then studied how the powerhouse of the cell (mitochondria) is responsible for controlling whole body energy balance and metabolism in the canonical site for energy balance control (hypothalamus) with Marc Claret, PhD and earned his Ph.D. in Biomedicine at the Barcelona University, Catalonia in 2015. He then became a KAVLI postdoctoral fellow and a Pathway to Independence fellow in Prof. Jeffrey M.Friedman laboratory at The Rockefeller University. There he conducted whole mount activity maps in energy states to decipher the role of two novel subsets of neurons in the Dorsal Raphe Nucleus of the brainstem in energy balance control. He joined the Department of Cellular and Molecular Physiology at Yale University School of Medicine as an Assistant Professor in July 2022.
The Schneeberger Pané laboratory employs state-of-the-art technologies in neuroscience combining unbiased whole mount imaging of circuits, activity and vasculature; molecular profiling single-cell gene expression technologies, neuoromodulation (optogenetics, and chemogenetics) to understand the fundamental principles in the brain governing homeostasis. The overarching goal of the laboratory is to advance in the understanding of how neuronal, immune and vascular networks coordinately control homeostasis, with a focus on energy homeostasis.
Appointments
Cellular & Molecular Physiology
Assistant ProfessorPrimary
Other Departments & Organizations
- Cellular & Molecular Physiology
- Interdepartmental Neuroscience Program
- Janeway Society
- Molecular Medicine, Pharmacology, and Physiology
- Neural Disorders
- Neuroscience Track
- Wu Tsai Institute
- Yale Center for Molecular and Systems Metabolism (YMSM)
- Yale Combined Program in the Biological and Biomedical Sciences (BBS)
Education & Training
- NIH Pathway to Independence K99 Fellow
- The Rockefeller University (2022)
- Instructor
- Yale University (2022)
- KAVLI Postdoctoral Fellow
- The Rockefeller University (2019)
- JPB Postdoctoral Fellow
- The Rockefeller University (2017)
- PhD
- Barcelona University, Medicine (2015)
- MS
- Barcelona University, Biomedicine (2011)
- BS
- Barcelona University, Pharmacy (2010)
Research
Overview
Medical Subject Headings (MeSH)
ORCID
0000-0001-7369-104X
Research at a Glance
Yale Co-Authors
Publications Timeline
Tamas Horvath, DVM, PhD
Ken Huaijin Loh, PhD
Marcelo de Oliveira Dietrich, MD, PhD
María José Ortuño Romero, PhD
Publications
2024
Burning Question: How Does Our Brain Process Positive and Negative Cues Associated with Thermosensation?
Grajales-Reyes JG, Chen B, Meseguer D, Schneeberger M. Burning Question: How Does Our Brain Process Positive and Negative Cues Associated with Thermosensation? Physiology (Bethesda) 2024, 39: 0. PMID: 38536114, DOI: 10.1152/physiol.00034.2023.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsNeuro-Adipokine Crosstalk in Alzheimer’s Disease
Chen, B.; Schneeberger, M. Neuro-Adipokine Crosstalk in Alzheimer’s Disease. Int. J. Mol. Sci. 2024, 25, 5932.Peer-Reviewed Original ResearchMaternal nutritional programming shapes the cerebral landscape.
Chen B, de Launoit E, Renier N, Schneeberger M. Maternal nutritional programming shapes the cerebral landscape. Trends Endocrinol Metab 2024, 35: 367-370. PMID: 37949733, DOI: 10.1016/j.tem.2023.10.008.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCentral myelin dysfunction bridges obesity and neurological diseases.
Chen B, de Launoit E, Renier N, Schneeberger M. Central myelin dysfunction bridges obesity and neurological diseases. Trends Endocrinol Metab 2024, 35: 7-10. PMID: 37798242, DOI: 10.1016/j.tem.2023.09.004.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2023
Dynamic rewiring of neurovasculature in health and disease.
Chen B, Meseguer D, Renier N, Schneeberger M. Dynamic rewiring of neurovasculature in health and disease. Trends Mol Med 2023, 29: 786-788. PMID: 37487781, DOI: 10.1016/j.molmed.2023.06.011.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsFGF21 counteracts alcohol intoxication by activating the noradrenergic nervous system.
Choi M, Schneeberger M, Fan W, Bugde A, Gautron L, Vale K, Hammer RE, Zhang Y, Friedman JM, Mangelsdorf DJ, Kliewer SA. FGF21 counteracts alcohol intoxication by activating the noradrenergic nervous system. Cell Metab 2023, 35: 429-437.e5. PMID: 36889282, DOI: 10.1016/j.cmet.2023.02.005.Peer-Reviewed Original Research
2022
Pharmacological targeting of glutamatergic neurons within the brainstem for weight reduction.
Schneeberger M, Brice NL, Pellegrino K, Parolari L, Shaked JT, Page KJ, Marchildon F, Barrows DW, Carroll TS, Topilko T, Mulligan VM, Newman R, Doyle K, Bürli R, Barker DF, Glen A, Ortuño MJ, Nectow AR, Renier N, Cohen P, Carlton M, Heintz N, Friedman JM. Pharmacological targeting of glutamatergic neurons within the brainstem for weight reduction. Nat Metab 2022, 4: 1495-1513. PMID: 36411386, DOI: 10.1038/s42255-022-00677-8.Peer-Reviewed Original ResearchRemission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue.
Gonzalez-Franquesa A, Gama-Perez P, Kulis M, Szczepanowska K, Dahdah N, Moreno-Gomez S, Latorre-Pellicer A, Fernández-Ruiz R, Aguilar-Mogas A, Hoffman A, Monelli E, Samino S, Miró-Blanch J, Oemer G, Duran X, Sanchez-Rebordelo E, Schneeberger M, Obach M, Montane J, Castellano G, Chapaprieta V, Sun W, Navarro L, Prieto I, Castaño C, Novials A, Gomis R, Monsalve M, Claret M, Graupera M, Soria G, Wolfrum C, Vendrell J, Fernández-Veledo S, Enríquez JA, Carracedo A, Perales JC, Nogueiras R, Herrero L, Trifunovic A, Keller MA, Yanes O, Sales-Pardo M, Guimerà R, Blüher M, Martín-Subero JI, Garcia-Roves PM. Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue. Redox Biol 2022, 54: 102353. PMID: 35777200, DOI: 10.1016/j.redox.2022.102353.Peer-Reviewed Original Research
2021
Melanocortin 4 receptor stimulation prevents antidepressant-associated weight gain in mice caused by long-term fluoxetine exposure.
Ortuño MJ, Schneeberger M, Ilanges A, Marchildon F, Pellegrino K, Friedman JM, Ducy P. Melanocortin 4 receptor stimulation prevents antidepressant-associated weight gain in mice caused by long-term fluoxetine exposure. The Journal Of Clinical Investigation 2021, 131 PMID: 34673574, PMCID: PMC8670849, DOI: 10.1172/JCI151976.Peer-Reviewed Original ResearchMultifaceted actions of melanin-concentrating hormone on mammalian energy homeostasis.
Al-Massadi O, Dieguez C, Schneeberger M, López M, Schwaninger M, Prevot V, Nogueiras R. Multifaceted actions of melanin-concentrating hormone on mammalian energy homeostasis. Nature Reviews. Endocrinology 2021, 17: 745-755. PMID: 34608277, DOI: 10.1038/s41574-021-00559-1.Peer-Reviewed Original Research
Academic Achievements and Community Involvement
activity Swiss National Foundation
Peer Review Groups and Grant Study SectionsReviewerDetails2022 - Presentactivity Israel Science Foundation
Peer Review Groups and Grant Study SectionsReviewerDetails2022 - Presentactivity Spanish National Evaluation and Foresight Agency
Peer Review Groups and Grant Study SectionsReviewerDetails2019 - Presentactivity ANR:AAP French National Agency
Peer Review Groups and Grant Study SectionsReviewerDetails2020 - Presentactivity Argentinian Ministry of Science and Technology
Peer Review Groups and Grant Study SectionsReviewerDetails2020 - Present
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Cellular & Molecular Physiology
333 Cedar Street, B-Wing, E Level
New Haven, Connecticut 06510
United States