Eric K. Holder, MD
Assistant Professor of Orthopaedics & RehabilitationCards
About
Research
Publications
2024
FACTFINDERS for PATIENT SAFETY: Preventing procedure-related complications: Epidural lipomatosis and postpartum steroid exposure
D'Souza R, Zheng P, Christolias G, Holder E, Lee H, Miller D, Raghunandan A, Smith C, Patel J, Committee I. FACTFINDERS for PATIENT SAFETY: Preventing procedure-related complications: Epidural lipomatosis and postpartum steroid exposure. Interventional Pain Medicine 2024, 3: 100408. DOI: 10.1016/j.inpm.2024.100408.Peer-Reviewed Original ResearchEpidural steroid injectionsSpinal epidural lipomatosisProcedure-related complicationsSpinal stenosisSteroid injectionHypothalamic-pituitary-adrenalEpidural lipomatosisSteroid exposureDuration of breastfeedingLow-level evidenceResponse to steroid administrationPatient safetySteroid administrationNeurological compromiseInsufficient evidencePostpartumBreast milkLipomatosisStenosisSpinalInfant exposureSteroidsComplicationsInjectionBreastfeeding
2023
FactFinders for patient safety: Preventing local anesthetic-related complications: Local anesthetic chondrotoxicity and stellate ganglion blocks
Saffarian M, Holder E, Mattie R, Smith C, Christolias G, Patel J, McCormick Z, Committee S. FactFinders for patient safety: Preventing local anesthetic-related complications: Local anesthetic chondrotoxicity and stellate ganglion blocks. Interventional Pain Medicine 2023, 2: 100282. DOI: 10.1016/j.inpm.2023.100282.Peer-Reviewed Original ResearchAnesthetic-related complicationsStellate ganglion blockLocal anestheticsGanglion blockAdverse outcomesIntraarticular injectionUltrasound guidanceCurrent evidenceFluoroscopic techniquePatient safetyChondrotoxic effectsVascular structuresEquivalent volumeAnestheticsSoft tissue visualizationComplicationsChondrotoxicityTissue visualizationRiskEvidenceBupivacaineRopivacaineChondrotoxicRisk of SARS‐CoV‐2 following joint and epidural corticosteroid injections: A retrospective study
Raju R, Holder E, Dundas M, Liang J, Donham R. Risk of SARS‐CoV‐2 following joint and epidural corticosteroid injections: A retrospective study. Pain Practice 2023, 24: 472-482. PMID: 37994676, DOI: 10.1111/papr.13321.Peer-Reviewed Original ResearchPCR positivity ratesCharlson Comorbidity IndexInjection groupPositivity rateCS injectionsControl groupCorticosteroid injectionSevere comorbiditiesPolymerase chain reaction positivitySARS-CoV-2 PCREpidural corticosteroid injectionsRetrospective chart reviewTertiary care centerCohort of patientsSignificant disease burdenCoronavirus disease 2019 (COVID-19) pandemicSignificant higher rateSARS-CoV-2Disease 2019 pandemicMultivariate regression analysisComorbidity indexPatients 18Chart reviewRetrospective studyImmunosuppressive effectsFactFinders for patient safety: Understanding potential procedure-related complications: RFN/multifidus atrophy, intradiscal biologics, and facet cyst rupture
Nguyen M, Saffarian M, Smith C, Holder E, Lee H, Marshall B, Mattie R, Patel J, Schneider B, McCormick Z, Committee S. FactFinders for patient safety: Understanding potential procedure-related complications: RFN/multifidus atrophy, intradiscal biologics, and facet cyst rupture. Interventional Pain Medicine 2023, 2: 100248. DOI: 10.1016/j.inpm.2023.100248.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsLumbar medial branch radiofrequency neurotomyPotential procedure-related complicationsProcedure-related complicationsMultifidus atrophyCyst ruptureHigh-quality prospective studiesMedial branch radiofrequency neurotomyNerve root compressionRisk of complicationsReports of complicationsCross-sectional imagingRadiofrequency neurotomyRoot compressionProspective studyIntradiscal injectionBiologic interventionsClinical relevanceComplicationsLarger sample sizeAtrophyNatural historyPatient safetyAvailable evidenceComparison groupBiologicsDoes Lumbar Medial Branch Radiofrequency Neurotomy Cause Multifidus Atrophy? Spine Intervention Society Factfinders for Patient Safety
Nguyen M, Holder EK, Marshall BJ, Smith CC, Patel J, McCormick ZL. Does Lumbar Medial Branch Radiofrequency Neurotomy Cause Multifidus Atrophy? Spine Intervention Society Factfinders for Patient Safety. February 2023Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsEpidural Injections for Radicular Pain Due to Spinal Stenosis Caused by Lipomatosis. Spine Intervention Society Factfinders for Patient Safety
D'Souza RS, Christiolas G, Holder EK, Lee H, Smith C, Patel J. Epidural Steroid Injections for Radicular Pain Due to Spinal Stenosis caused by Lipomatosis. Spine Intervention Society Factfinders for Patient Safety.June 2023Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2022
Changes in the Utilization of Lumbosacral Epidural Injections Between 2010 and 2019
Ratnasamy PP, Gouzoulis MJ, Kammien AJ, Holder EK, Grauer JN. Changes in the Utilization of Lumbosacral Epidural Injections Between 2010 and 2019. Spine 2022, 47: 1669-1674. PMID: 36281568, PMCID: PMC9643603, DOI: 10.1097/brs.0000000000004467.Peer-Reviewed Original ResearchConceptsElixhauser Comorbidity IndexEpidural injectionTransforaminal injectionsSpinal epidural injectionDescriptive epidemiologic studyLumbosacral epidural injectionNumber of injectionsCurrent Procedural Terminology codingCaudal injectionComorbidity indexPatient agePatient characteristicsPearlDiver databaseLumbar pathologyTerms of specialtyInsurance authorizationPractice patternsService utilizationAverage patientEpidemiologic studiesMedicaid coveragePatientsTransforaminalMedicare coverageUtilization trendsAtypical knee pain.
Berger GK, Milligan K, Holder EK, Schwab JM, Rubin LE. Atypical knee pain. The Journal Of Family Practice 2022, 71: 181-184. PMID: 35730713, DOI: 10.12788/jfp.0404.Peer-Reviewed Case Reports and Technical NotesIs there an association between lumbosacral epidural lipomatosis and lumbosacral epidural steroid injections? A comprehensive narrative literature review
Holder EK, Raju R, Dundas MA, Husu EN, McCormick ZL. Is there an association between lumbosacral epidural lipomatosis and lumbosacral epidural steroid injections? A comprehensive narrative literature review. North American Spine Society Journal (NASSJ) 2022, 9: 100101. PMID: 35243452, PMCID: PMC8857075, DOI: 10.1016/j.xnsj.2022.100101.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsLumbosacral epidural lipomatosisLumbosacral epidural steroid injectionsSpinal epidural lipomatosisEpidural steroid injectionsEpidural lipomatosisRadicular painCorticosteroid exposureSteroid injectionSystemic steroid exposureHigh-quality studiesPatients' clinical dataDevelopment/progressionIndependent causal relationshipCurrent management recommendationsSteroid exposureTreatment optionsRisk factorsClinical dataPainLipomatosisNarrative literature reviewNotable associationGoogle ScholarPotential painComprehensive narrative literature reviewChondrotoxicity: Which Local Anesthetics are Safest for Intraarticular Injections? Spine Intervention Society Factfinders for Patient Safety
Holder E.K., Christolias G, Saffarian M, Patel J, McCormick ZL. Chondrotoxicity: Which Local Anesthetics are Safest for Intraarticular Injection? Spine Intervention Society Factfinders for Patient Safety. Interventional Pain Medicine. April 2022.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
Academic Achievements and Community Involvement
Clinical Care
Overview
Eric K. Holder, MD, is a physiatrist (a doctor who practices physical medicine and rehabilitation). He focuses on treating problems with the muscles, joints and nerves without surgery.
Dr. Holder specializes in interventional spine and musculoskeletal care, including sports injuries. He takes a conservative care approach whenever possible. With each new patient, his strategy is to listen closely to the patient’s story in order to make a precise diagnosis. He then partners with his patients to formulate a comprehensive individualized care plan based on the patient’s condition, preferences and goals. To do this, he may consult with providers of rheumatologic, neurologic and surgical treatments.
“To me, it is very important to spend enough time with each patient so that he or she leaves every encounter with an understanding of the next step in their care plan,” he says.
Dr. Holder uses specialized physical therapy programs, and when indicated, minimally invasive procedures, such as ultrasound- or fluoroscopy-guided injections to assist in restoration of function and to improve quality of life.
As a physiatrist, Dr. Holder takes “a holistic functional approach” when evaluating a problem, as opposed to only thinking about one particular body part or injury. He looks to address not only current concerns, but also makes sure care plans are designed to promote long-term well-being. “I am passionate about working with my patients to promote active, productive and healthy lifestyles,” he says.
Clinical Specialties
Fact Sheets
Physiatry (Physical Medicine and Rehabilitation)
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Board Certifications
Lifestyle Medicine
- Certification Organization
- Intl Bd of Lifestyle Medicine
- Original Certification Date
- 2022
Physical Medicine & Rehabilitation
- Certification Organization
- AB of Physical Medicine & Rehabilitation
- Original Certification Date
- 2017
Yale Medicine News
Links & Media
News
- December 19, 2023Source: Yahoo! News
The 1 Thing Doctors Refuse To Do During The Holidays
- October 10, 2022Source: Washington Post
Ways to ease painful joints caused by osteoarthritis
- February 22, 2022
Is there an association between lumbosacral epidural lipomatosis and lumbosacral epidural steroid injections? A comprehensive narrative literature review
- July 27, 2020Source: Yale Medicine
How to Set Up Your ‘Pandemic’ Home Office the Right Way