2024
Adjuvant Everolimus in Non–Clear Cell Renal Cell Carcinoma
Gulati S, Tangen C, Ryan C, Vaishampayan U, Shuch B, Barata P, Pruthi D, Bergerot C, Tripathi A, Lerner S, Thompson I, Lara P, Pal S. Adjuvant Everolimus in Non–Clear Cell Renal Cell Carcinoma. JAMA Network Open 2024, 7: e2425288. PMID: 39106067, PMCID: PMC11304111, DOI: 10.1001/jamanetworkopen.2024.25288.Peer-Reviewed Original ResearchConceptsChromophobe renal cell carcinomaRecurrence-free survivalPapillary renal cell carcinomaRenal cell carcinomaNon-clear cell renal cell carcinomaResected renal cell carcinomaCell renal cell carcinomaOverall survivalWeeks of treatmentCell carcinomaAdverse eventsClinical trialsHazard ratioPhase 3 randomized clinical trialWeeks of everolimusHigher adverse eventsRate of adverse eventsIntermediate-high riskIntervention groupVery-high-riskCox regression modelsPotential treatment benefitsClinical trial dataTreatment-NaivePartial nephrectomy
2023
Impact of race and payor status on patterns of utilization of partial and radical nephrectomy in patients with localized renal cell carcinoma (RCC).
Barragan-Carrillo R, Dallas K, Tripathi A, Govindarajan A, Zengin Z, Meza L, Philip E, Castro D, Chehrazi-Raffle A, Chawla N, Hsu J, Dizman N, Eilber K, Bergerot C, Pal S. Impact of race and payor status on patterns of utilization of partial and radical nephrectomy in patients with localized renal cell carcinoma (RCC). Journal Of Clinical Oncology 2023, 41: 614-614. DOI: 10.1200/jco.2023.41.6_suppl.614.Peer-Reviewed Original Research
2022
External validation of yonsei nomogram predicting chronic kidney disease development after partial nephrectomy: An international, multicenter study
Raheem A, Landi I, Alowidah I, Capitanio U, Montorsi F, Larcher A, Derweesh I, Ghali F, Mottrie A, Mazzone E, De Naeyer G, Campi R, Sessa F, Carini M, Minervini A, Raman J, Rjepaj C, Kriegmair M, Autorino R, Veccia A, Mir M, Claps F, Choi Y, Ham W, Santok G, Tadifa J, Syling J, Furlan M, Simeone C, Bada M, Celia A, Carrión D, Bazan A, Ruiz C, Malki M, Barber N, Hussain M, Micali S, Puliatti S, Ghaith A, Hagras A, Ghoneem A, Eissa A, Alqahtani A, Rumaih A, Alwahabi A, Alenzi M, Pavan N, Traunero F, Antonelli A, Porcaro A, Illiano E, Costantini E, Rha K. External validation of yonsei nomogram predicting chronic kidney disease development after partial nephrectomy: An international, multicenter study. International Journal Of Urology 2022, 30: 308-317. PMID: 36478459, DOI: 10.1111/iju.15108.Peer-Reviewed Original ResearchConceptsNew-onset CKDCKD stageChronic kidney disease developmentExternal validationCKD stage ICT1 renal massesKidney disease developmentPreoperative eGFRPatient ageConsecutive patientsMulticenter studyTumor sizePartial nephrectomyRenal massesProgression rateGood calibration propertiesStage IProgression probabilityPatientsNomogramIndividual riskCKDDisease developmentEGFRMedian valueComparison of Long-term Outcomes for Young and Healthy Patients with cT1a and cT3a Renal Cell Carcinoma Treated with Partial Nephrectomy
Tan W, Koelker M, Campain N, Cole A, Labban M, Mossanen M, Barod R, Kibel A, Chang S, Bex A, Trinh Q. Comparison of Long-term Outcomes for Young and Healthy Patients with cT1a and cT3a Renal Cell Carcinoma Treated with Partial Nephrectomy. European Urology Focus 2022, 9: 333-335. PMID: 36241545, DOI: 10.1016/j.euf.2022.09.018.Peer-Reviewed Original ResearchConceptsRenal cell carcinomaLocally advanced kidney cancerPositive surgical marginsPartial nephrectomyAdvanced kidney cancerSurgical marginsKidney cancerRate of surgical marginComparison of long-term outcomesNational Cancer DatabaseMedian Follow-UpPatients aged <Cox proportional-hazards modelLong-term outcomesPresence of tumorCharlson Comorbidity IndexChronic kidney diseaseProportional-hazards modelCT1a tumorsCT1b groupHigher ACMNephron preservationCT stagingSolitary kidneyCell carcinomaRobotic Partial Nephrectomy in the Treatment of a Posterior Excluded Caliceal Diverticulum with a Renal Calculus
Alter K, Yoshitake S, Sterling J, Park J, Elsamra S. Robotic Partial Nephrectomy in the Treatment of a Posterior Excluded Caliceal Diverticulum with a Renal Calculus. Videourology 2022, 36 DOI: 10.1089/vid.2022.0037.Peer-Reviewed Original ResearchCaliceal diverticulumShockwave lithotripsy treatmentPartial nephrectomyRenal calculiHistory of recurrent urinary tract infectionsSevere left flank painRecurrent urinary tract infectionsNo competing financial interestsArchived patient consentLeft renal calculusUncomplicated hospital courseExtracorporeal shockwave lithotripsy treatmentRobotic partial nephrectomyUrinary tract infectionPostoperative day 1History of nephrolithiasisWarm ischemia timeFollow-up visitRight PNVideo recording/publicationFlank painTreatment of stonesIntraoperative complicationsIntraoperative ultrasonographyTract infectionsRobot-Assisted Laparoscopic Ureterocalicostomy and Pyelolithotomy for Proximal Ureteral Stricture
Lee G, Patel H, Sterling J, Elsamra S. Robot-Assisted Laparoscopic Ureterocalicostomy and Pyelolithotomy for Proximal Ureteral Stricture. Videourology 2022, 36 DOI: 10.1089/vid.2022.0035.Peer-Reviewed Original ResearchProximal ureteral strictureUreteral strictureLower pole calixLaparoscopic ureterocalicostomyIntrarenal pelvisNo competing financial interestsRight lateral decubitus positionArchived patient consentDecreased stone burdenEstimated blood lossLateral decubitus positionStone basket extractionDa Vinci Xi robotVideo recording/publicationRecurrent nephrolithiasisWedge resectionPartial nephrectomyRobotic portsAssistant portIntraoperative ultrasonographyBlood lossDrain removalUreteropelvic junctionRenal hilumRetrograde pyelographyTechniques of robotic assisted partial nephrectomy with renal vein tumor thrombectomy and reconstruction: UCSD experience
Patel D, Ghali F, Greear G, Holst D, Derweesh I. Techniques of robotic assisted partial nephrectomy with renal vein tumor thrombectomy and reconstruction: UCSD experience. Urology Video Journal 2022, 13: 100124. DOI: 10.1016/j.urolvj.2022.100124.Peer-Reviewed Original ResearchPartial nephrectomyTumor thrombusRenal veinSegmental branchesImmediate post-operative complicationsPost-operative day twoT3 renal cell carcinomaPost-operative day threePost-operative complicationsTotal operative timeWarm ischemia timeMulti-institutional analysisMain renal veinRenal cell carcinomaRobotic partial nephrectomyInvasive partial nephrectomyBowel mobilizationPT3a diseaseSided tumorsFinal pathologyBlood lossRenal functionTumor thrombectomyThird patientOperative time
2021
A Clinical Decision Aid to Support Personalized Treatment Selection for Patients with Clinical T1 Renal Masses: Results from a Multi-institutional Competing-risks Analysis
Psutka SP, Gulati R, Jewett MAS, Fadaak K, Finelli A, Legere L, Morgan TM, Pierorazio PM, Allaf ME, Herrin J, Lohse CM, Thompson R, Boorjian SA, Atwell TD, Schmit GD, Costello BA, Shah ND, Leibovich BC. A Clinical Decision Aid to Support Personalized Treatment Selection for Patients with Clinical T1 Renal Masses: Results from a Multi-institutional Competing-risks Analysis. European Urology 2021, 81: 576-585. PMID: 34862099, PMCID: PMC10351331, DOI: 10.1016/j.eururo.2021.11.002.Peer-Reviewed Original ResearchConceptsCancer-specific mortalityRenal cortical massesRadical nephrectomyPartial nephrectomyActive surveillancePersonalized treatment selectionClavien gradeRisk calculatorThermal ablationTreatment selectionEastern Cooperative Oncology Group performance statusClinical T1 renal massesSurgeon/hospital volumeHigh-volume referral centerInitial radical nephrectomyCharlson Comorbidity IndexCompeting-risks regressionConsecutive adult patientsGlomerular filtration rateClavien grade 3Risk of deathBody mass indexT1 renal massesRisk of mortalityClinical decision aidV05-10 PARTIAL NEPHRECTOMY IN THE TREATMENT OF A POSTERIOR EXCLUDED CALYCEAL DIVERTICULUM WITH A RENAL CALCULUS
Yoshitake S, Sterling J, Elsamra S. V05-10 PARTIAL NEPHRECTOMY IN THE TREATMENT OF A POSTERIOR EXCLUDED CALYCEAL DIVERTICULUM WITH A RENAL CALCULUS. Journal Of Urology 2021, 206: e389-e389. DOI: 10.1097/ju.0000000000002012.10.Peer-Reviewed Original ResearchPartial nephrectomyCalyceal diverticulumWarm ischemia time length during on-clamp partial nephrectomy: dose it really matter?
Abdel Raheem A, Alowidah I, Capitanio U, Montorsi F, Larcher A, Derweesh I, Ghali F, Mottrie A, Mazzone E, DE Naeyer G, Campi R, Sessa F, Carini M, Minervini A, Raman J, Rjepaj C, Kriegmair M, Autorino R, Veccia A, Mir M, Claps F, Choi Y, Ham W, Tadifa J, Santok G, Furlan M, Simeone C, Bada M, Celia A, Carrión D, Aguilera Bazan A, Ballesteros Ruiz C, Malki M, Barber N, Hussain M, Micali S, Puliatti S, Alwahabi A, Alqahtani A, Rumaih A, Ghaith A, Ghoneem A, Hagras A, Eissa A, Alenzi M, Pavan N, Traunero F, Antonelli A, Porcaro A, Illiano E, Costantini E, Rha K. Warm ischemia time length during on-clamp partial nephrectomy: dose it really matter? Minerva Urologica E Nefrologica 2021, 74: 194-202. PMID: 34308610, DOI: 10.23736/s2724-6051.21.04466-9.Peer-Reviewed Original ResearchConceptsClamp partial nephrectomyWarm ischemia timePartial nephrectomyEGFR preservationCKD stageEGFR valuesProgression rateGroup IILong-term renal functionGroup ILong-term renal function outcomeUnivariable Cox regression analysisMedian eGFR valueRenal function outcomesInternational cohort studyRenal functional recoveryCox regression analysisML/Regression analysisDisease upgradingEGFR declineEGFR changeCohort studyRenal functionFinal cohortMajor Urological Cancer Surgery for Patients is Safe and Surgical Training Should Be Encouraged During the COVID-19 Pandemic: A Multicentre Analysis of 30-day Outcomes
Tan W, Arianayagam R, Khetrapal P, Rowe E, Kearley S, Mahrous A, Pal R, Fowler W, Heer R, Elajnaf M, Douglas-Moore J, Griffiths T, Voss J, Wilby D, Al Kadhi O, Noel J, Vasdev N, McKay A, Ahmad I, Abu-Nayla I, Lamb B, Hill G, Narahari K, Kynaston H, Yousuf A, Kusuma V, Cresswell J, Cooke P, Chakravarti A, Barod R, Bex A, Kelly J, group O. Major Urological Cancer Surgery for Patients is Safe and Surgical Training Should Be Encouraged During the COVID-19 Pandemic: A Multicentre Analysis of 30-day Outcomes. European Urology Open Science 2021, 25: 39-43. PMID: 33458711, PMCID: PMC7796655, DOI: 10.1016/j.euros.2021.01.005.Peer-Reviewed Original ResearchRadical nephrectomyRadical prostatectomyRadical cystectomyPartial nephrectomyHigher American Society of Anesthesiologists (ASA) scoreCounseling patientsGenitourinary (GU) cancersAmerican Society of Anesthesiologists (ASA) scoreAssociated with longer hospital LOSRisk of progressionHigher ASA scoreHospital length of stayUrologic cancer surgeryMinimally invasive approachLonger hospital LOSCase statusLength of stayASA scoreInvasive approachMulticentre analysisCancer operationsUrological cancersCancer surgeryHospital lengthKidney cancer
2020
Impact of positive surgical margins on survival after partial nephrectomy in localized kidney cancer: analysis of the National Cancer Database
Ryan S, Patel D, Ghali F, Patel S, Sarkar R, Yim K, Eldefrawy A, Cotta B, Bradshaw A, Meagher M, Hamilton Z, Murphy J, Derweesh I. Impact of positive surgical margins on survival after partial nephrectomy in localized kidney cancer: analysis of the National Cancer Database. Minerva Urologica E Nefrologica 2020, 73: 233-244. PMID: 32748614, DOI: 10.23736/s2724-6051.20.03728-5.Peer-Reviewed Original ResearchConceptsPositive surgical marginsKaplan-Meier analysisRenal cell carcinomaNational Cancer DatabaseOverall survivalPartial nephrectomyMultivariable analysisSurgical marginsPathological stageCancer DatabaseCox regression multivariable analysisN0M0 renal cell carcinomaUS National Cancer DatabaseImpact of PSMRegression multivariable analysisPT3a diseaseCause mortalityMargin statusNegative marginsResection strategyCell carcinomaAggressive surveillanceRetrospective analysisKidney cancerPatientsComparison of renal functional outcomes of active surveillance and partial nephrectomy in the management of oncocytoma
Meagher M, Lane B, Capitanio U, Mehrazin R, Bradshaw A, Noyes S, Larcher A, Eldefrawy A, Ghali F, Patel D, Bruinius J, Dutt R, Keiner C, Miller N, Wan F, Montorsi F, Derweesh I. Comparison of renal functional outcomes of active surveillance and partial nephrectomy in the management of oncocytoma. World Journal Of Urology 2020, 39: 1195-1201. PMID: 32556559, DOI: 10.1007/s00345-020-03299-5.Peer-Reviewed Original ResearchConceptsDe novo chronic kidney diseaseChronic kidney diseaseKaplan-Meier analysisPartial nephrectomyActive surveillanceMultivariable analysisBaseline eGFRTumor sizeFunctional outcomeFunctional declineCKD-free survivalGreater functional declineHigher RENAL scoreLower baseline eGFRRenal functional preservationRegression multivariable analysisClinical tumor sizeRenal functional outcomesTumor diameterKidney diseaseRENAL scoreFunctional preservationMedian changeRetrospective analysisSelect circumstancesOncologic and Functional Outcomes of Radical and Partial Nephrectomy in pT3a Pathologically Upstaged Renal Cell Carcinoma: A Multi-institutional Analysis
Patel S, Uzzo R, Larcher A, Peyronnet B, Lane B, Pruthi D, Reddy M, Capitanio U, Joshi S, Noyes S, Eldefrawy A, Ghali F, Meagher M, Hamilton Z, Yim K, Nasseri R, Bradshaw A, Dey S, Kirmiz S, Wan F, Liss M, Bensalah K, Montorsi F, Derweesh I. Oncologic and Functional Outcomes of Radical and Partial Nephrectomy in pT3a Pathologically Upstaged Renal Cell Carcinoma: A Multi-institutional Analysis. Clinical Genitourinary Cancer 2020, 18: e723-e729. PMID: 32600941, DOI: 10.1016/j.clgc.2020.05.002.Peer-Reviewed Original ResearchConceptsKaplan-Meier analysisRenal cell carcinomaPT3a renal cell carcinomaRecurrence-free survivalRadical nephrectomyPartial nephrectomyOverall survivalMultivariable analysisCell carcinomaFunctional outcomeDe novo eGFRGlomular filtration rateClinical T stageMulticenter retrospective analysisRisk of recurrenceMulti-institutional analysisPT3a upstagingOncologic outcomesSecondary outcomesPrimary outcomeIndependent predictorsSurvival outcomesT stagePositive marginsPredictive factorsFactors Associated With Receipt of Partial Nephrectomy or Minimally Invasive Surgery for Patients With Clinical T1a and T1b Renal Masses: Implications for Regionalization of Care
Sterling J, Rivera-Núñez Z, Patel HV, Farber NJ, Kim S, Radadia KD, Modi PK, Goyal S, Parikh R, Weiss RE, Kim IY, Elsamra SE, Jang TL, Singer EA. Factors Associated With Receipt of Partial Nephrectomy or Minimally Invasive Surgery for Patients With Clinical T1a and T1b Renal Masses: Implications for Regionalization of Care. Clinical Genitourinary Cancer 2020, 18: e643-e650. PMID: 32389458, PMCID: PMC7502425, DOI: 10.1016/j.clgc.2020.03.011.Peer-Reviewed Original ResearchConceptsNational Cancer Data BaseRenal cell carcinomaPartial nephrectomyClinical T1 renal cell carcinomaT1 renal cell carcinomaInvasive surgeryUtilization of MISRegionalization of careLower socioeconomic groupsT1b renal massesClinical T1aCT1a patientsCT1a tumorsCT1b patientsCT1b tumorsRCC surgeryTreatment disparitiesCell carcinomaPatient populationRenal massesInvasive treatmentPatientsAcademic centersLogistic regressionPrivate insuranceAssociation of cytoreductive nephrectomy and survival in the immune checkpoint inhibitor era.
Miccio J, Ma S, Oladeru O, Yang D, Peters G, Jethwa K, Park H, Hurwitz M, Leapman M, Sprenkle P, Nguyen P, Yu J, Johung K. Association of cytoreductive nephrectomy and survival in the immune checkpoint inhibitor era. Journal Of Clinical Oncology 2020, 38: 748-748. DOI: 10.1200/jco.2020.38.6_suppl.748.Peer-Reviewed Original ResearchMetastatic renal cell carcinomaCytoreductive nephrectomyICI eraImproved overall survivalNational Cancer DatabaseOverall survivalIFN eraFuhrman gradeBenefit of CNEfficacy of ICIsClinical T stageCox regression analysisTreatment facility typeRenal cell carcinomaCARMENA trialInterferon eraMultivariable associateN0 diseaseOS benefitProspective reevaluationMedian ageT stageCell carcinomaCancer DatabasePartial nephrectomyImpact of diabetes mellitus on functional and survival outcomes in renal cell carcinoma: An international multicenter study.
Dutt R, Meagher M, Patil D, Saito K, Patel D, Ghali F, Keiner C, Miller N, Bradshaw A, Wan F, Yasuda Y, Fujii Y, Master V, Derweesh I. Impact of diabetes mellitus on functional and survival outcomes in renal cell carcinoma: An international multicenter study. Journal Of Clinical Oncology 2020, 38: 666-666. DOI: 10.1200/jco.2020.38.6_suppl.666.Peer-Reviewed Original ResearchRenal cell carcinomaIndependent risk factorChronic kidney diseaseKaplan-Meier analysisRadical nephrectomyMultivariable analysisPartial nephrectomyRisk factorsPresence of DMFunctional declineDM statusOverall survivalKidney functionRCC patientsTumor sizeCell carcinomaRenal functional declineAfrican American raceInternational multicenter studyEffects of DMNDM patientsRN patientsCause mortalityWorse OSDiabetes mellitusAssociation of robotic partial nephrectomy for clinical T2a renal mass with improved trifecta outcome compared to open partial nephrectomy: A single surgeon comparative analysis.
Ghali F, Elbakry A, Hamilton Z, Nasseri R, Eldefrawy A, Ryan S, Yim K, Patel S, Bradshaw A, Meagher M, Reddy M, Lee H, Derweesh I. Association of robotic partial nephrectomy for clinical T2a renal mass with improved trifecta outcome compared to open partial nephrectomy: A single surgeon comparative analysis. Journal Of Clinical Oncology 2020, 38: 653-653. DOI: 10.1200/jco.2020.38.6_suppl.653.Peer-Reviewed Original ResearchRobotic partial nephrectomyOpen PNPartial nephrectomyMultivariable analysisRENAL scoreRenal massesLower blood lossFirst-line optionMedian RENAL scoreAchievement of trifectaEGFR recoveryHospital staySelect patientsBlood lossConsecutive patientsMajor complicationsPositive marginsTumor sizeFunctional outcomeTrifecta achievementTrifecta outcomesRetrospective analysisMAIN OUTCOMESurgical qualityTrifecta ratesDoes pathologic upstaging to PT3A portend a worsened prognosis when compared to non-upstaged PT3A renal cell carcinoma: Analysis of the National Cancer Database.
Patel D, Ghali F, Meagher M, Bradshaw A, Patel S, Keiner C, Miller N, Dutt R, Murphy J, Derweesh I. Does pathologic upstaging to PT3A portend a worsened prognosis when compared to non-upstaged PT3A renal cell carcinoma: Analysis of the National Cancer Database. Journal Of Clinical Oncology 2020, 38: 624-624. DOI: 10.1200/jco.2020.38.6_suppl.624.Peer-Reviewed Original ResearchPT3a renal cell carcinomaRenal cell carcinomaNational Cancer DatabasePartial nephrectomyClinical stageOverall survivalPT3a tumorsCell carcinomaPathological upstagingUpstaged tumorsCancer DatabaseT3a renal cell carcinomaMultivariable Cox proportional hazardsKaplan-Meier survival analysisPre-treatment detectionRisk stratification protocolCharlson Comorbidity IndexImproved overall survivalFinal pathological analysisAJCC staging systemKaplan-Meier analysisSmaller tumor sizeLower clinical stagePositive margin statusCox proportional hazards
2019
Robotic partial nephrectomy for clinical T2a renal mass is associated with improved trifecta outcome compared to open partial nephrectomy: a single surgeon comparative analysis
Ghali F, Elbakry A, Hamilton Z, Yim K, Nasseri R, Patel S, Eldefrawy A, Ryan S, Bradshaw A, Meagher M, Bree K, Reddy M, Lee H, Derweesh I. Robotic partial nephrectomy for clinical T2a renal mass is associated with improved trifecta outcome compared to open partial nephrectomy: a single surgeon comparative analysis. World Journal Of Urology 2019, 38: 1113-1122. PMID: 31701211, DOI: 10.1007/s00345-019-02994-2.Peer-Reviewed Original ResearchConceptsPartial nephrectomyOpen PNRenal massesMultivariable analysisRENAL scoreResultsMean tumor sizeLower blood lossBurden of morbidityFirst-line optionT2 renal massesOpen partial nephrectomyRobotic partial nephrectomyMedian RENAL scoreAchievement of trifectaEGFR recoveryHospital staySelect patientsBlood lossConsecutive patientsMajor complicationsMethodsRetrospective analysisPositive marginsTumor sizeFunctional outcomeTrifecta achievement
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply