2024
Effects of ketamine on GABAergic and glutamatergic activity in the mPFC: biphasic recruitment of GABA function in antidepressant-like responses
Fogaça M, Daher F, Picciotto M. Effects of ketamine on GABAergic and glutamatergic activity in the mPFC: biphasic recruitment of GABA function in antidepressant-like responses. Neuropsychopharmacology 2024, 50: 673-684. PMID: 39390105, PMCID: PMC11845475, DOI: 10.1038/s41386-024-02002-1.Peer-Reviewed Original ResearchNovelty suppressed feeding testMedial prefrontal cortexSucrose splash testEffects of ketamineAntidepressant-like responseMajor depressive disorderGABAergic activityGABA interneuronsGlutamatergic activityGABA neuronsSustained antidepressant effectsGABA neuron activityLow dose of ketamineAdministration of ketamineDose of ketamineAntidepressant responseAntidepressant developmentSplash testAntidepressant effectsPrefrontal cortexDepressive disorderChemogenetic inhibitionBehavioral actionsAssociated with disruptionGABA functionLess attention to emotional faces is associated with low empathy and prosociality in 12‐to 20‐month old infants
Donohue M, Camacho M, Drake J, Schwarzlose R, Brady R, Hoyniak C, Hennefield L, Wakschlag L, Rogers C, Barch D, Luby J. Less attention to emotional faces is associated with low empathy and prosociality in 12‐to 20‐month old infants. Infancy 2024, 29: 113-136. PMID: 38173191, PMCID: PMC10872599, DOI: 10.1111/infa.12569.Peer-Reviewed Original ResearchConceptsNegative emotional facesEmotional facesDevelopment of empathyEye regionAssociated with less empathyEye region of facesAssociated with lower empathyEmotional processing skillsRegion of facesAngry facesFearful facesEmotional processingInfant attentionLow empathyAssociated with disruptionProsocial behaviorDecreased attentionProsocial helpingDiverse sampleComfort behaviourDevelopmental periodEffect sizeProsocialityProcess skillsEmpathy
2023
Dehydroepiandrosterone mediates associations between trauma‐related symptoms and anterior pituitary volume in children and adolescents
Picci G, Casagrande C, Ott L, Petro N, Christopher‐Hayes N, Johnson H, Willett M, Okelberry H, Wang Y, Stephen J, Calhoun V, Wilson T. Dehydroepiandrosterone mediates associations between trauma‐related symptoms and anterior pituitary volume in children and adolescents. Human Brain Mapping 2023, 44: 6388-6398. PMID: 37853842, PMCID: PMC10681633, DOI: 10.1002/hbm.26516.Peer-Reviewed Original ResearchConceptsTrauma-related symptomsAnxiety symptomsPituitary volumeAnterior pituitary volumeConsistent with adult findingsHigh-resolution T1-weighted MRI scansPG volumeEarly life stressLevels of dehydroepiandrosteroneT1-weighted MRI scansDehydroepiandrosterone levelsPituitary glandResponse to stressComorbid anxietyNeurobiological sequelaeSubclinical anxietyLife stressAnxiety/depression symptomsElevated anxietyAdult findingsAssociated with disruptionDevelopmental sampleHealthy youthTrained ratersPubertal window
2021
Preterm refraction and ocular biometry in children with and without retinopathy of prematurity in the first year of life
Kaur S, Dogra M, Sukhija J, Samanta R, Singh S, Grover S, Katoch D. Preterm refraction and ocular biometry in children with and without retinopathy of prematurity in the first year of life. Journal Of American Association For Pediatric Ophthalmology And Strabismus 2021, 25: 271.e1-271.e6. PMID: 34582950, DOI: 10.1016/j.jaapos.2021.05.012.Peer-Reviewed Original ResearchConceptsRisk of retinopathy of prematurityRetinopathy of prematurityAxial lengthLaser therapySevere ROPMean refractive errorZone 1 diseaseShorter axial lengthOcular biometryRefractive errorHigh-severity groupOutcome measuresCorneal steepnessPremature infantsPremature childrenMyopiaProspective studyAssociated with disruptionStudy cohortAnisometropiaSevere groupLaser treatmentInfantsKeratometryStudy parameters
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply