2025
Intracranial Aneurysms in Autosomal Dominant Polycystic Kidney Disease: A Practical Approach to Screening and Management
Borghol A, Alkhatib B, Zayat R, Ravikumar N, Munairdjy Debeh F, Ghanem A, Mina J, Mao M, Dahl N, Hickson L, Aslam N, Torres V, Brown R, Tawk R, Chebib F. Intracranial Aneurysms in Autosomal Dominant Polycystic Kidney Disease: A Practical Approach to Screening and Management. Mayo Clinic Proceedings 2025, 100: 1030-1050. PMID: 40319406, DOI: 10.1016/j.mayocp.2025.02.003.Peer-Reviewed Original ResearchConceptsAutosomal dominant polycystic kidney diseaseDominant polycystic kidney diseasePolycystic kidney diseaseIntracranial aneurysmsSubarachnoid hemorrhageFamily history of intracranial aneurysmsProgressive kidney function declineKidney diseaseSymptoms related to mass effectRisk factorsBrain magnetic resonance angiographyHistory of intracranial aneurysmsControl of risk factorsFocal neurological deficitsFollow-up careKidney function declineGenetic kidney disordersCharacteristics of intracranial aneurysmsIndicator of subarachnoid hemorrhageMagnetic resonance angiographyNonmodifiable risk factorsPrevent adverse outcomesSaccular intracranial aneurysmsCase-fatality rateThunderclap headache
2023
Hypoxemia in School-age Children Undergoing One-lung Ventilation: A Retrospective Cohort Study from the Multicenter Perioperative Outcomes Group
Templeton T, Krol B, Miller S, Lee L, Mathis M, Vishneski S, Chatterjee D, Gupta R, Shroeder R, Saha A, Schonberger R. Hypoxemia in School-age Children Undergoing One-lung Ventilation: A Retrospective Cohort Study from the Multicenter Perioperative Outcomes Group. Anesthesiology 2023, 140: 25-37. PMID: 37738432, DOI: 10.1097/aln.0000000000004781.Peer-Reviewed Original ResearchConceptsIncreased risk of hypoxemiaOne-lung ventilationRisk of hypoxemiaRight-sided casesIncreased riskSevere hypoxemiaDuration of one-lung ventilationVideo-assisted thoracoscopic surgeryRoom air oxygen saturationLow tidal volume ventilationRisk factorsOxygen saturationMulticenter Perioperative Outcomes Group databasePrevalence of hypoxemiaAssociated with hypoxemiaAssociated with increased riskTidal volume ventilationRetrospective cohort studySelection operator regression analysisChildren 4Nonmodifiable risk factorsMultivariate least absolute shrinkageSchool-aged childrenThoracoscopic surgeryThoracic surgery
2019
A Mechanistic Model of Gut–Brain Axis Perturbation and High-Fat Diet Pathways to Gut Microbiome Homeostatic Disruption, Systemic Inflammation, and Type 2 Diabetes
Lew K, Starkweather A, Cong X, Judge M. A Mechanistic Model of Gut–Brain Axis Perturbation and High-Fat Diet Pathways to Gut Microbiome Homeostatic Disruption, Systemic Inflammation, and Type 2 Diabetes. Biological Research For Nursing 2019, 21: 384-399. PMID: 31113222, DOI: 10.1177/1099800419849109.Peer-Reviewed Original ResearchConceptsGut-brain axisGut-brain axis pathwayHigh-fat dietDNA sequencing technologiesPro-inflammatory pathwaysMechanistic modelSequencing technologiesGut microbiomeHuman microbiomeHomeostatic disruptionProgression of T2DInsulin resistanceNonmodifiable risk factorsSystemic inflammationGutHigh-fatMicrobiomePathwayHomeostatic imbalanceMetabolic diseasesRisk factorsLow-grade systemic inflammationAmerican populationTranslocation of endotoxinWall permeabilityCorrelation of Soft Tissue Swelling and Timing to Surgery With Acute Wound Complications for Operatively Treated Ankle and Other Lower Extremity Fractures
Riedel MD, Parker A, Zheng M, Briceno J, Staffa SJ, Miller CP, Kaiser PB, Wu JS, Zurakowski D, Kwon JY. Correlation of Soft Tissue Swelling and Timing to Surgery With Acute Wound Complications for Operatively Treated Ankle and Other Lower Extremity Fractures. Foot & Ankle International 2019, 40: 526-536. PMID: 30688533, DOI: 10.1177/1071100718820352.Peer-Reviewed Original ResearchConceptsWound complicationsTiming of surgeryLower extremity fracturesEdema indexAnkle fracturesExtremity fracturesRisk factorsComplication rateTobacco historyPatient-specific risk factorsAcute wound complicationsWound complication riskIndependent risk factorPostoperative wound complicationsProspective cohort studyWound complication rateNonmodifiable risk factorsSoft tissue edemaSoft-tissue swellingLower extremity traumaAssessment of swellingClosed ankleCohort studyContralateral extremityFracture care
2016
Epidemiology and Risk Factors
Amin H, Schindler J. Epidemiology and Risk Factors. 2016, 37-42. DOI: 10.1007/978-3-319-39605-7_5.ChaptersRisk factorsStroke riskIndividual stroke riskSignificant global health burdenModifiable risk factorsNonmodifiable risk factorsGlobal health burdenPutative risk factorsStroke physiciansInsulin resistanceOutpatient settingHealth burdenFuture burdenStrokeBurdenRiskFactorsInternistsEpidemiologyPhysiciansTrials
2013
Modifiable Risk Factors for Pneumonia Requiring Hospitalization of Community‐Dwelling Older Adults: The Health, Aging, and Body Composition Study
Juthani‐Mehta M, De Rekeneire N, Allore H, Chen S, O'Leary JR, Bauer DC, Harris TB, Newman AB, Yende S, Weyant RJ, Kritchevsky S, Quagliarello V, Study F. Modifiable Risk Factors for Pneumonia Requiring Hospitalization of Community‐Dwelling Older Adults: The Health, Aging, and Body Composition Study. Journal Of The American Geriatrics Society 2013, 61: 1111-1118. PMID: 23772872, PMCID: PMC3714374, DOI: 10.1111/jgs.12325.Peer-Reviewed Original ResearchConceptsModifiable risk factorsIncident mobility limitationCommunity-dwelling older adultsBody Composition StudyRisk factorsPlaque scoresMobility limitationsOlder adultsNovel modifiable risk factorsProspective observational cohort studyObservational cohort studyNonmodifiable risk factorsCases of pneumoniaHistory of pneumoniaCommunity-dwelling adultsAverage attributable fractionMonths of baselineCohort studyExpiratory volumePneumonia preventionDental examinationPrimary outcomeOral hygieneMale sexAttributable fraction
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