2022
N‐Acyl Amides from Neisseria meningitidis and Their Role in Sphingosine Receptor Signaling
Cho W, York AG, Wang R, Wyche TP, Piizzi G, Flavell RA, Crawford JM. N‐Acyl Amides from Neisseria meningitidis and Their Role in Sphingosine Receptor Signaling. ChemBioChem 2022, 23: e202200490-e202200490. PMID: 36112057, PMCID: PMC9762135, DOI: 10.1002/cbic.202200490.Peer-Reviewed Original ResearchConceptsN-acyl amidesGram-negative opportunistic pathogenNeisseria meningitidisHuman-associated bacteriaBlood-brain barrierBioactive small moleculesInterleukin-10 signalingMacrophage cell typesN-acyltransferaseInterleukin-17AG proteinsHuman diseasesT cellsReceptor signalingCell typesImmune systemHigh mortalityHuman microbiotaRepresentative membersOpportunistic pathogenMeningitidisSignalingSmall moleculesN.Meningitis
2021
Risk of Disseminated Gonococcal Infections With Terminal Complement Blockade
Graciaa SH, Graciaa DS, Yildirim I, Chonat S. Risk of Disseminated Gonococcal Infections With Terminal Complement Blockade. Journal Of Pediatric Hematology/Oncology 2021, 44: e493-e495. PMID: 33560079, PMCID: PMC8556643, DOI: 10.1097/mph.0000000000002075.Peer-Reviewed Original ResearchConceptsTerminal complement blockadeComplement blockadeGonococcal infectionClonal hematopoietic stem cell disordersDisseminated gonococcal infectionHematopoietic stem cell disordersQuality of lifeStem cell disordersParoxysmal nocturnal hemoglobinuriaComplement protein C5Complement-mediated hemolysisProphylactic antibioticsIntravascular hemolysisAppropriate immunizationsAzithromycin resistanceCell disordersNocturnal hemoglobinuriaNeisseria gonorrhoeaeProtein C5Infection riskPatientsMonoclonal antibodiesNeisseria meningitidisBlockadeInfection
2020
Correction to: A pooled analysis of the LAMP assay for the detection of Neisseria meningitidis
Fan SJ, Tan HK, Xu YC, Chen YZ, Xie TA, Pan ZY, Ouyang S, Li Q, Li XY, Li ZX, Guo XG. Correction to: A pooled analysis of the LAMP assay for the detection of Neisseria meningitidis. BMC Infectious Diseases 2020, 20: 560. PMID: 32736603, PMCID: PMC7395387, DOI: 10.1186/s12879-020-05300-3.Peer-Reviewed Original ResearchA pooled analysis of the LAMP assay for the detection of Neisseria meningitidis
Fan SJ, Tan HK, Xu YC, Chen YZ, Xie TA, Pan ZY, Ouyang S, Li Q, Li XY, Li ZX, Guo XG. A pooled analysis of the LAMP assay for the detection of Neisseria meningitidis. BMC Infectious Diseases 2020, 20: 525. PMID: 32689953, PMCID: PMC7372874, DOI: 10.1186/s12879-020-05250-w.Peer-Reviewed Original ResearchConceptsLoop-mediated isothermal amplificationBacterial meningitisFunnel plotPublication biasHigh mortality rateLAMP assayWeb of ScienceSROC curvePooled analysisMortality rateClinical practiceDiagnostic accuracyMajor causeMeningococcusNeisseria meningitidisSummary receiverCharacteristic curveMeningitisReliable diagnosisDeeks' funnel plotIsothermal amplificationDepressed areasOriginal studyMeningitidisBacterial cultureMeningococcal carriage in young adults six years after meningococcal C conjugate (MCC) vaccine catch-up campaign in Salvador, Brazil
Ferreira V, Ferreira Í, Chang H, Nunes A, Topaz N, Pimentel E, Moura A, Ribeiro G, Feitosa C, Reis M, Wang X, Campos L. Meningococcal carriage in young adults six years after meningococcal C conjugate (MCC) vaccine catch-up campaign in Salvador, Brazil. Vaccine 2020, 38: 2995-3002. PMID: 32115294, DOI: 10.1016/j.vaccine.2020.02.050.Peer-Reviewed Original ResearchConceptsMeningococcal carriageCarriage prevalenceRT-PCRN. meningitidisYoung adultsMeningococcal carriage studyMeningococcal serogroup CCross-sectional studyMeningococcal carriage prevalenceAppropriate vaccination strategiesStandard microbiology methodsSix yearsMeningococcal carriage isolatesNG isolatesMale sexSerogroup CHerd protectionVaccination strategiesCarriage isolatesCarriage studiesOropharyngeal swabsReal-time PCRNull genotypeContinuous vaccinationNeisseria meningitidis
2008
A Prospective Study of Etiology of Childhood Acute Bacterial Meningitis, Turkey - Volume 14, Number 7—July 2008 - Emerging Infectious Diseases journal - CDC
Ceyhan M, Yildirim I, Balmer P, Borrow R, Dikici B, Turgut M, Kurt N, Aydogan A, Ecevit C, Anlar Y, Gulumser O, Tanir G, Salman N, Gurler N, Hatipoglu N, Hacimustafaoglu M, Celebi S, Coskun Y, Alhan E, Celik U, Camcioglu Y, Secmeer G, Gur D, Gray S. A Prospective Study of Etiology of Childhood Acute Bacterial Meningitis, Turkey - Volume 14, Number 7—July 2008 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2008, 14: 1089-1096. PMID: 18598630, PMCID: PMC2600347, DOI: 10.3201/eid1407.070938.Peer-Reviewed Original ResearchConceptsAcute bacterial meningitisBacterial meningitisSerogroup WCSF samplesChildhood acute bacterial meningitisHaemophilus influenzae type bInfectious Diseases journal - CDCEtiology of meningitisInfluenzae type bCerebrospinal fluid samplesPCR-positive samplesProspective studyBacterial etiologyMeningococcal diseaseVaccination policyCost of diseaseMeningitisS. pneumoniaeStreptococcus pneumoniaeClinical diagnosisEtiologyN. meningitidisNeisseria meningitidisDiseaseType B
1989
Blood cultures in the management of febrile outpatients later found to have bacteremia
Alario A, Nelson E, Shapiro E. Blood cultures in the management of febrile outpatients later found to have bacteremia. The Journal Of Pediatrics 1989, 115: 195-199. PMID: 2787855, DOI: 10.1016/s0022-3476(89)80064-2.Peer-Reviewed Original ResearchConceptsBlood culturesPositive blood culturesFebrile outpatientsHaemophilus influenzae type bSerious focal infectionsEpisodes of bacteremiaCases of meningitisInfluenzae type bPersistent bacteremiaPersistent symptomsFocal complicationsFocal infectionOutpatientsStreptococcus pneumoniaeBacteremiaNeisseria meningitidisType BComplicationsPatientsChildrenMeningitisSymptomsInfectionCliniciansPneumoniae
1986
Risk factors for development of bacterial meningitis among children with occult bacteremia
Shapiro E, Aaron N, Wald E, Chiponis D. Risk factors for development of bacterial meningitis among children with occult bacteremia. The Journal Of Pediatrics 1986, 109: 15-19. PMID: 3088242, DOI: 10.1016/s0022-3476(86)80564-9.Peer-Reviewed Original ResearchConceptsOccult bacteremiaBacterial meningitisInfluenzae type bClinical characteristicsInitial visitLumbar punctureRisk factorsRelative riskHaemophilus influenzae type bYale-New Haven HospitalH. influenzae type bType BChildren's HospitalPossible confounding effectsMeningitisBacteremiaEstimates of riskS. pneumoniaeStreptococcus pneumoniaeLogistic regressionN. meningitidisNeisseria meningitidisHospitalChildrenRisk
1985
Prophylaxis for Bacterial Meningitis
Shapiro E. Prophylaxis for Bacterial Meningitis. 1985, 69: 269-280. PMID: 3990434, DOI: 10.1016/s0025-7125(16)31042-2.Peer-Reviewed Original Research
1982
Prophylaxis for contacts of patients with meningococcal or Haemophilus influenzae type b disease
SHAPIRO E. Prophylaxis for contacts of patients with meningococcal or Haemophilus influenzae type b disease. The Pediatric Infectious Disease Journal 1982, 1: 132-138. PMID: 6757888, DOI: 10.1097/00006454-198203000-00015.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsRole of prophylaxisHaemophilus influenzae type b diseaseHaemophilus influenzae type bContacts of patientsCases of meningitisType b diseaseDiagnosis of meningitisInfluenzae type bB diseaseNonepidemic periodsProphylaxisPatientsNeisseria meningitidisPreventive measuresDiseaseType BMeningitisRecommendations of expertsFamily membersSecondary spreadRecent studiesClose contactCurrent understandingIllnessPhysicians
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