2021
The Optimal Cell Salvage Settings to Maximize Hematocrit and Minimize Potassium Using the Cobe BRAT2 Autologous Blood Recovery Unit
Smith N, Kim S, Simmons Q, Lin H, Romano D, Boydston E, DeMaria S, Zerillo J. The Optimal Cell Salvage Settings to Maximize Hematocrit and Minimize Potassium Using the Cobe BRAT2 Autologous Blood Recovery Unit. Journal Of Cardiothoracic And Vascular Anesthesia 2021, 36: 1893-1900. PMID: 34446326, DOI: 10.1053/j.jvca.2021.07.040.Peer-Reviewed Original ResearchConceptsRed blood cellsInfusion rateSingle-center studyRed cellsAssociated with decreased hematocritIndependent of infusion rateFaster infusion ratesHematocrit pre-Salvage settingPotassium changesBanked red blood cellsInfusionBlood cellsHigher hematocritHematocritML/minLow potassiumCellsLactateDevice settingsGlucoseDosing of Direct Oral Anticoagulants in Patients with Moderate Chronic Kidney Disease in US Clinical Practice: Results from the Outcomes Registry for Better Informed Treatment of AF (ORBIT-AF II)
Jackson LR, Schrader P, Thomas L, Steinberg BA, Blanco R, Allen LA, Fonarow GC, Freeman JV, Gersh BJ, Kowey PR, Mahaffey KW, Naccarelli G, Reiffel J, Singer DE, Peterson ED, Piccini JP. Dosing of Direct Oral Anticoagulants in Patients with Moderate Chronic Kidney Disease in US Clinical Practice: Results from the Outcomes Registry for Better Informed Treatment of AF (ORBIT-AF II). American Journal Of Cardiovascular Drugs 2021, 21: 553-561. PMID: 33786798, DOI: 10.1007/s40256-021-00473-x.Peer-Reviewed Original ResearchConceptsModerate chronic kidney diseaseChronic kidney diseaseAtrial fibrillationRoutine clinical practiceClinical practiceInappropriate dosingOral anticoagulantsKidney diseaseConclusionIn routine clinical practiceMedian CHA2DS2VASc scoreComorbid medical conditionsDirect oral anticoagulantsUS clinical practiceBetter Informed TreatmentCockcroft-Gault formulaOne-thirdML/minCrCl 30CHA2DS2VASc scoreCreatinine clearanceRenal functionMedian ageDosage adjustmentOutcomes RegistryPrescribed dosesFactors Related to Survival in Low–Glomerular Filtration Rate Cohorts Undergoing Lung Transplant
Funamoto M, Osho AA, Li SS, Moonsamy P, Mohan N, Ong CS, Melnitchouk S, Sundt TM, Astor TL, Villavicencio MA. Factors Related to Survival in Low–Glomerular Filtration Rate Cohorts Undergoing Lung Transplant. The Annals Of Thoracic Surgery 2021, 112: 1797-1804. PMID: 33421391, DOI: 10.1016/j.athoracsur.2020.12.021.Peer-Reviewed Original ResearchConceptsGlomerular filtration rateLung transplantationImproved survivalPreoperative glomerular filtration rateML/minNormal glomerular filtration rateLung transplant listingOrgan Sharing databaseLogistic regression analysisLung recipientsTransplant listingLung transplantAdult patientsPropensity matchingSharing databaseOutpatient statusUnited NetworkKaplan-MeierFiltration rateSuperior survivalPropensity score methodsPatientsTransplantationMultivariate analysisOutpatient recipients
2020
Decline in renal function and oral anticoagulation dose reduction among patients with atrial fibrillation
Inohara T, Holmes DN, Pieper K, Blanco RG, Allen LA, Fonarow GC, Gersh BJ, Hylek EM, Ezekowitz MD, Kowey PR, Reiffel JA, Naccarelli GV, Chan PS, Mahaffey KW, Singer DE, Freeman JV, Steinberg BA, Peterson ED, Piccini JP. Decline in renal function and oral anticoagulation dose reduction among patients with atrial fibrillation. Heart 2020, 106: 358-364. PMID: 31911503, DOI: 10.1136/heartjnl-2019-315792.Peer-Reviewed Original ResearchConceptsAtrial fibrillationRenal functionOral anticoagulationDose reductionAtrial Fibrillation II registryBetter Informed TreatmentML/minCrCl declineOral anticoagulantsCreatinine clearanceOutcomes RegistryGuideline criteriaPatientsPackage insertsUS FoodDrug AdministrationMean declineInformed TreatmentNOACsAnticoagulationFibrillationRegistryDosingCrClOne-fourth
2015
Rate of Contrast Extravasation on Computed Tomographic Angiography Predicts Hematoma Expansion and Mortality in Primary Intracerebral Hemorrhage
Brouwers HB, Battey TW, Musial HH, Ciura VA, Falcone GJ, Ayres AM, Vashkevich A, Schwab K, Viswanathan A, Anderson CD, Greenberg SM, Pomerantz SR, Ortiz CJ, Goldstein JN, Gonzalez RG, Rosand J, Romero JM. Rate of Contrast Extravasation on Computed Tomographic Angiography Predicts Hematoma Expansion and Mortality in Primary Intracerebral Hemorrhage. Stroke 2015, 46: 2498-2503. PMID: 26243220, PMCID: PMC4550492, DOI: 10.1161/strokeaha.115.009659.Peer-Reviewed Original ResearchConceptsPrimary intracerebral hemorrhageHematoma expansionContrast extravasationIntracerebral hemorrhageSpot signExtravasation rateTomographic angiographyConsecutive intracerebral hemorrhage patientsML/minContrast extravasation rateAcute intracerebral hemorrhageIntracerebral hemorrhage patientsMultivariable logistic regressionRate of bleedingIntracerebral hemorrhage volumeSpot sign presenceHospital mortalityMultivariable analysisHemorrhage patientsPostcontrast CTHemorrhage volumeSemiautomated softwareMortalityLogistic regressionHemorrhage
2011
Noninvasive cardiac output monitoring with bioreactance as an alternative to invasive instrumentation for preclinical drug evaluation in beagles
Heerdt PM, Wagner CL, DeMais M, Savarese JJ. Noninvasive cardiac output monitoring with bioreactance as an alternative to invasive instrumentation for preclinical drug evaluation in beagles. Journal Of Pharmacological And Toxicological Methods 2011, 64: 111-118. PMID: 21440649, DOI: 10.1016/j.vascn.2011.03.006.Peer-Reviewed Original ResearchConceptsCardiac outputAortic blood flowDrug-induced changesBlood flowAcute drug-induced changesNoninvasive cardiac output monitoringNon-invasive measurementOpen-chest beaglesNeuromuscular blocking drugsPreclinical drug evaluationCardiac output monitoringDrug evaluation studiesML/minSimultaneous CO measurementsBlocking drugsAcute alterationsAortic rootPreclinical screeningChest instrumentationNICOMCO measurementsOutput monitoringDrug evaluationInvasive measurementsInvasive instrumentation
2006
Serum Urea Nitrogen, Creatinine, and Estimators of Renal Function: Mortality in Older Patients With Cardiovascular Disease
Smith GL, Shlipak MG, Havranek EP, Foody JM, Masoudi FA, Rathore SS, Krumholz HM. Serum Urea Nitrogen, Creatinine, and Estimators of Renal Function: Mortality in Older Patients With Cardiovascular Disease. JAMA Internal Medicine 2006, 166: 1134-1142. PMID: 16717177, DOI: 10.1001/archinte.166.10.1134.Peer-Reviewed Original ResearchConceptsCreatinine levelsMyocardial infarctionHeart failureMDRD eGFRCardiovascular patientsSerum urea nitrogen levelsOlder cardiovascular patientsHeart failure patientsModification of DietGlomerular filtration rateUrea nitrogen levelsProportional hazards modelSerum urea nitrogenML/minMagnitude of riskRenal measuresPostdischarge mortalityRenal dysfunctionOlder patientsRenal functionFailure patientsOutcome prognosticationRetrospective cohortFiltration rateCardiovascular disease
2003
The impact of protein intake on renal function decline in women with normal renal function or mild renal insufficiency.
Knight EL, Stampfer MJ, Hankinson SE, Spiegelman D, Curhan GC. The impact of protein intake on renal function decline in women with normal renal function or mild renal insufficiency. Annals Of Internal Medicine 2003, 138: 460-7. PMID: 12639078, DOI: 10.7326/0003-4819-138-6-200303180-00009.Peer-Reviewed Original ResearchConceptsGlomerular filtration rateMild renal insufficiencyNormal renal functionRenal function declineNurses' Health StudyRenal insufficiencyRenal functionFunction declineHigh protein intakeProtein intakeNondairy animal proteinHealth StudyHigh intakeSemi-quantitative food frequency questionnaireHigher total protein intakeML/minProspective cohort studyRenal function changesSevere renal insufficiencyFood frequency questionnaireMultivariate linear regression analysisTotal protein intakeBorderline statistical significancePercent of womenLow protein intake
1998
Experimental confirmation of effectiveness of fenestration in acute aortic dissection
Morales D, Quin J, Braxton J, Hammond G, Gusberg R, Elefteriades J. Experimental confirmation of effectiveness of fenestration in acute aortic dissection. The Annals Of Thoracic Surgery 1998, 66: 1679-1683. PMID: 9875771, DOI: 10.1016/s0003-4975(98)00901-1.Peer-Reviewed Original ResearchConceptsRenal arterial flowFemoral blood pressureAortic dissectionBlood pressureAortic fenestrationAortic distensibilityCarotid pressureArterial flowAcute aortic dissectionML/minSubsequent fenestrationOrgan ischemiaRenal flowInfrarenal aortaContinued clinical applicationBlood flowAnimal modelsFenestrationDissectionClinical applicationT-testDistensibilityMinIschemiaAortaLower extremity volumetric arterial blood flow in normal subjects
Holland C, Brown J, Scoutt L, Taylor K. Lower extremity volumetric arterial blood flow in normal subjects. Ultrasound In Medicine & Biology 1998, 24: 1079-1086. PMID: 9833575, DOI: 10.1016/s0301-5629(98)00103-3.Peer-Reviewed Original ResearchConceptsArterial blood flowCommon femoralSuperficial femoralBlood flowVascular diseaseHealthy subjectsMuscle massAnkle-brachial index valuesML/minCalf circumference measurementCross-sectional areaArterial cross-sectional areaVolumetric blood flowVessel cross-sectional areaDorsalis pedisClinical studiesDoppler ultrasoundDoppler waveformsNormal subjectsCircumference measurementsNormal valuesSignificant differencesFemoralDiseaseSubjectsReduction in arteriovenous graft impairment: Results of a vascular access surveillance protocol
Cayco A, Abu-Alfa A, Mahnensmith R, Perazella M. Reduction in arteriovenous graft impairment: Results of a vascular access surveillance protocol. American Journal Of Kidney Diseases 1998, 32: 302-308. PMID: 9708617, DOI: 10.1053/ajkd.1998.v32.pm9708617.Peer-Reviewed Original ResearchConceptsDynamic venous pressureHistorical control groupVenous pressureArteriovenous graftsSurveillance protocolStudy groupBlood flow rateThrombosis rateControl groupSimilar historical control groupHemodialysis vascular accessSynthetic arteriovenous graftsLower thrombosis rateML/minGraft impairmentVenous stenosisHD sessionVascular accessVascular stenosisPatientsScreening testStenosisStudy periodFrustrating problemConsecutive readings
1991
Contrasting Effects of Various Potassium Salts on Renal Citrate Excretion*
SAKHAEE K, ALPERN R, JACOBSON H, PAK C. Contrasting Effects of Various Potassium Salts on Renal Citrate Excretion*. The Journal Of Clinical Endocrinology & Metabolism 1991, 72: 396-400. PMID: 1899422, DOI: 10.1210/jcem-72-2-396.Peer-Reviewed Original ResearchConceptsCitrate clearanceAcid-base statusUrinary citratePotassium citrateRenal citrate excretionMeq/dayPotassium citrate treatmentWeeks of treatmentNet acid excretionCitraturic responseUrinary ammoniumOral administrationCitrate excretionAcid excretionPotassium chlorideUrinary bicarbonateCitrate treatmentAlkali loadPotassium bicarbonateClearanceML/minExcretionDaysTreatmentTitratable acid
1985
Adenosine Triphosphate—Magnesium Chloride Ameliorates Reperfusion Injury Following Ischemia as Determined by Phosphorus Nuclear Magnetic Resonance
Sumpio B, Chaudry I, Baue A. Adenosine Triphosphate—Magnesium Chloride Ameliorates Reperfusion Injury Following Ischemia as Determined by Phosphorus Nuclear Magnetic Resonance. JAMA Surgery 1985, 120: 233-240. PMID: 3872113, DOI: 10.1001/archsurg.1985.01390260091013.Peer-Reviewed Original ResearchConceptsIntracellular acidosisPerfusate flowATP levelsAdenosine triphosphate-magnesium chlorideRenal ATP levelsMinutes of reperfusionTissue ATP levelsEffects of ischemiaAdenosine triphosphateML/minPostischemic administrationReperfusion injuryRenal ischemiaWarm ischemiaATP-MgCl2ReperfusionIschemiaInorganic phosphate peakIntracellular adenosine triphosphatePi peakRat kidneyAcidosisATP depletionMinutesMagnetic resonance
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply