2024
Successful Investigational Phage Therapy for Pan-Resistant Bacterial Mediastinitis Following Type II Hybrid Aortic Arch Replacement
Hameed I, Ahmed A, Gandhi S, Nassiri N, Steinbacher D, Vallabhajosyula P. Successful Investigational Phage Therapy for Pan-Resistant Bacterial Mediastinitis Following Type II Hybrid Aortic Arch Replacement. JACC Case Reports 2024, 29: 102816. PMID: 39691337, PMCID: PMC11646902, DOI: 10.1016/j.jaccas.2024.102816.Peer-Reviewed Original ResearchSternal wound infectionWound infectionPhage therapyStanford type B aortic dissectionThoracic endovascular aortic repairType B aortic dissectionMediastinal wound infectionsAortic arch surgeryAortic arch replacementDelayed Sternal ClosureEndovascular aortic repairHybrid arch repairB aortic dissectionHybrid aortic arch replacementBacterial mediastinitisArch repairArch replacementArch surgeryAortic repairCardiac surgeryMediastinal drainsIntraoperative courseFlap reconstructionMorbid complicationSternal closure
2022
Long‐term risk of arch complications in Loeys Dietz syndrome patients undergoing proximal ascending aortic replacement
Weininger G, Zafar M, Ziganshin BA, Mori M, Papanikolaou D, Sekar RB, Amabile A, Degife E, O'Marr J, Geirsson A, Elefteriades JA, Assi R, Vallabhajosyula P. Long‐term risk of arch complications in Loeys Dietz syndrome patients undergoing proximal ascending aortic replacement. Journal Of Cardiac Surgery 2022, 37: 3688-3692. PMID: 35989525, DOI: 10.1111/jocs.16855.Peer-Reviewed Original ResearchConceptsLoeys-Dietz syndromeProximal aortic replacementAortic replacementLDS patientsLong-term riskLoeys-Dietz syndrome patientsPathogenic variantsUnknown significanceLower long-term riskRare connective tissue disorderAscending Aortic ReplacementTotal arch replacementAortic valve replacementRecords of patientsConnective tissue disordersWhole-exome genetic testingArch replacementMedian followLatest followValve replacementOperative coursePatient chartsAortic diameterAortic dimensionsAortic arch
2021
Aneurysms of the Branches of the Aortic Arch
Elefteriades J, Ziganshin B. Aneurysms of the Branches of the Aortic Arch. 2021, 175-176. DOI: 10.1007/978-3-030-78877-3_56.Peer-Reviewed Original Research
2020
Intraoperative retrograde TEVAR to control endoleak after emergent total arch replacement and frozen elephant trunk repair for ruptured Kommerell's diverticulum
Singh S, Chen JF, Assi R, Nassiri N, Vallabhajosyula P. Intraoperative retrograde TEVAR to control endoleak after emergent total arch replacement and frozen elephant trunk repair for ruptured Kommerell's diverticulum. Journal Of Cardiac Surgery 2020, 35: 3578-3580. PMID: 33085131, DOI: 10.1111/jocs.14950.Peer-Reviewed Case Reports and Technical NotesConceptsKommerell's diverticulumAberrant right subclavian arteryEmergent total arch replacementFrozen elephant trunk repairRuptured Kommerell diverticulumTotal arch replacementType Ia endoleakRight subclavian arteryElephant trunk repairOptimal surgical managementHybrid operating roomArch replacementIa endoleakIntramural hematomaSubclavian arterySurgical managementHybrid repairAortic archProximal extensionDiverticulumOperating roomEndoleak
2018
Fate of distal aorta after frozen elephant trunk and total arch replacement for type A aortic dissection in Marfan syndrome
Chen Y, Ma WG, Zhi AH, Lu L, Zheng J, Zhang W, Liu YM, Zhu JM, Elefteriades JA, Sun LZ. Fate of distal aorta after frozen elephant trunk and total arch replacement for type A aortic dissection in Marfan syndrome. Journal Of Thoracic And Cardiovascular Surgery 2018, 157: 835-849. PMID: 30635189, DOI: 10.1016/j.jtcvs.2018.07.096.Peer-Reviewed Original ResearchFrozen elephant trunk techniqueMaximal aortic sizeFrozen elephant trunkElephant trunk techniqueTotal arch replacementAortic dissectionAortic sizeDistal aortaArch replacementMarfan syndromeFalse lumenElephant trunkLate deathsRenal arteryTrue lumenEight-year incidenceFalse lumen obliterationPatent false lumenEvent-free survivalMid-descending aortaRadiologic evidenceReoperation rateAortic dilatationAortic remodelingLatest followHybrid arch surgery challenges other forms of arch treatment
Wallen TJ, Bavaria JE, Vallabhajosyula P. Hybrid arch surgery challenges other forms of arch treatment. The Journal Of Cardiovascular Surgery 2018, 59: 554-558. PMID: 29687970, DOI: 10.23736/s0021-9509.18.10516-7.Peer-Reviewed Original ResearchConceptsHybrid arch proceduresHigh-risk patientsArch proceduresArch replacementRisk patientsTotal arch replacement procedureAcceptable postoperative outcomesSignificant comorbid burdenSignificant operative riskAortic arch replacementProspective randomized trialsTotal arch replacementAortic arch pathologiesOptimal surgical managementHybrid procedureArch surgeryComorbid burdenPostoperative mortalityAortic remodelingArch pathologiesOperative riskPostoperative outcomesSignificant comorbiditiesCirculatory arrestCase series
2017
Does BioGlue contribute to anastomotic pseudoaneurysm after thoracic aortic surgery?
Ma WG, Ziganshin BA, Guo CF, Zafar MA, Sieller RS, Tranquilli M, Elefteriades JA. Does BioGlue contribute to anastomotic pseudoaneurysm after thoracic aortic surgery? Journal Of Thoracic Disease 2017, 9: 2491-2497. PMID: 28932555, PMCID: PMC5594166, DOI: 10.21037/jtd.2017.06.120.Peer-Reviewed Original ResearchAnastomotic pseudoaneurysm formationThoracic aortic diseaseThoracic aortic surgeryUse of BioGluePseudoaneurysm formationSurgical repairAortic diseaseAortic surgeryAnastomotic pseudoaneurysmFollow-up computed tomography scanEmergency/urgent surgeryAortic surgical proceduresThoracic aortic aneurysmComputed tomography scanArch replacementOperative survivorsAortic ulcerIntramural hematomaOperative mortalityUrgent surgeryNeurologic deficitsAortic dissectionSurgical indicationsHemostatic adjunctMean ageFate of remnant sinuses of Valsalva in patients with bicuspid and trileaflet valves undergoing aortic valve, ascending aorta, and aortic arch replacement
Milewski RK, Habertheuer A, Bavaria JE, Siki M, Szeto WY, Krause E, Korutla V, Desai ND, Vallabhajosyula P. Fate of remnant sinuses of Valsalva in patients with bicuspid and trileaflet valves undergoing aortic valve, ascending aorta, and aortic arch replacement. Journal Of Thoracic And Cardiovascular Surgery 2017, 154: 421-432. PMID: 28599977, DOI: 10.1016/j.jtcvs.2017.03.150.Peer-Reviewed Original ResearchConceptsAortic valve replacementBicuspid aortic valveAorta replacementTricuspid aortic valveValve replacementAortic valveValsalva dimensionsPreoperative sinusSinus segmentValvular morphologyValvular pathologyElective aortic valve replacementMultivariable Cox regression modelsAortic arch replacementKaplan-Meier analysisAortic valve morphologyCox regression modelAortic valvulopathyArch replacementSurgical managementAortic aneurysmAortic rootLongitudinal sinusValsalva groupPatients
2016
Single-Stage Total Arch Replacement Including Resection of Kommerell Diverticulum in a Patient With Loeys-Dietz Syndrome
Ong CS, Kasai Y, Fukushima S, Hibino N, Magruder T, Suarez-Pierre A, Cameron D, Vricella L. Single-Stage Total Arch Replacement Including Resection of Kommerell Diverticulum in a Patient With Loeys-Dietz Syndrome. World Journal For Pediatric And Congenital Heart Surgery 2016, 7: 651-654. PMID: 27521346, DOI: 10.1177/2150135116656979.Peer-Reviewed Original ResearchConceptsLoeys-Dietz syndromeKommerell's diverticulumTotal aortic arch replacementGenetic connective tissue disorderAortic arch replacementAortic aneurysmal diseaseConnective tissue disordersArch replacementAortic diverticulumPediatric patientsMedian sternotomyAneurysmal diseaseSurgical techniqueTissue disordersDiverticulumResectionPatientsSyndromeSubject of debateSternotomySurgeryDisease
2015
[Retracted] How to Perfuse: Concepts of Cerebral Protection during Arch Replacement
Habertheuer A, Wiedemann D, Kocher A, Laufer G, Vallabhajosyula P. [Retracted] How to Perfuse: Concepts of Cerebral Protection during Arch Replacement. BioMed Research International 2015, 2015: 981813. PMID: 26713319, PMCID: PMC4680049, DOI: 10.1155/2015/981813.Peer-Reviewed Original ResearchConceptsAntegrade cerebral perfusionCerebral protectionCerebral perfusionPerfusion strategyBilateral antegrade cerebral perfusionAvailable surgical strategiesCardiac surgery communityCerebral perfusion strategyComplex aortic pathologiesSingle-center dataDegree of hypothermiaComplete circulatory arrestArch replacementArch surgeryAortic pathologyArch reconstructionCirculatory arrestCirculatory managementEuropean multicenterHypothermic arrestIschemic insultThoracic aneurysmSurgical interventionSurgical strategySurgical approachHemiarch replacement with concomitant antegrade stent grafting of the descending thoracic aorta versus total arch replacement for treatment of acute DeBakey I aortic dissection with arch tear†
Vallabhajosyula P, Gottret JP, Robb JD, Szeto WY, Desai ND, Pochettino A, Bavaria JE. Hemiarch replacement with concomitant antegrade stent grafting of the descending thoracic aorta versus total arch replacement for treatment of acute DeBakey I aortic dissection with arch tear†. European Journal Of Cardio-Thoracic Surgery 2015, 49: 1256-1261. PMID: 26516196, DOI: 10.1093/ejcts/ezv374.Peer-Reviewed Original ResearchConceptsThoracic endovascular aortic repairDeBakey I aortic dissectionTotal arch replacementAcute DeBakey I aortic dissectionConventional total arch replacementArch tearMid-term outcomesAortic dissectionTEVAR groupArch replacementHemiarch reconstructionHemiarch replacementTear repairFalse lumen thrombosisEndovascular aortic repairHospital/30-day mortalityAortic dissection patientsActuarial survivalTEVAR patientsCardiogenic shockStent graftingAortic repairDistal reconstructionCardiopulmonary bypassClinical presentation
2014
Aortic Valve Morphology Determines the Presentation and Surgical Approach to Acute Type A Aortic Dissection
Rylski B, Desai ND, Bavaria JE, Vallabhajosyula P, Moser W, Pochettino A, Szeto WY, Milewski RK. Aortic Valve Morphology Determines the Presentation and Surgical Approach to Acute Type A Aortic Dissection. The Annals Of Thoracic Surgery 2014, 97: 1991-1997. PMID: 24786861, DOI: 10.1016/j.athoracsur.2013.12.090.Peer-Reviewed Original ResearchConceptsTricuspid aortic valveBAV patientsAortic valve morphologyHospital mortalityAortic dissectionTAV patientsAcute Type A Aortic DissectionBicuspid aortic valve syndromeType A Aortic DissectionValve morphologyA Aortic DissectionSevere aortic insufficiencyTotal arch replacementAortic root replacementAortic root repairMedian followProximal reoperationAcute typeArch replacementCardiogenic shockAortic insufficiencyRoot replacementAortic diameterAorta diameterSurgical approach
2013
Type I and Type II hybrid aortic arch replacement: postoperative and mid-term outcome analysis.
Vallabhajosyula P, Szeto W, Desai N, Bavaria JE. Type I and Type II hybrid aortic arch replacement: postoperative and mid-term outcome analysis. Annals Of Cardiothoracic Surgery 2013, 2: 280-7. PMID: 23977595, PMCID: PMC3741847, DOI: 10.3978/j.issn.2225-319x.2013.05.09.Peer-Reviewed Original ResearchHybrid aortic arch replacementAortic arch replacementThoracic endovascular repairArch vessel debranchingArch replacementArch aneurysmAverage cardiopulmonary bypass timeAortic arch surgeryAortic reoperation ratesGreater comorbid burdenHybrid arch techniquesPrimary aortic pathologyCardiopulmonary bypass timeHybrid arch repairAortic arch aneurysmCirculatory arrest timeRenal failure rateSafe treatment modalityReoperative cardiac surgeryType IType III patientsType III repairType II repairArch dissectionArch surgeryType II arch hybrid debranching procedure.
Vallabhajosyula P, Szeto WY, Desai N, Komlo C, Bavaria JE. Type II arch hybrid debranching procedure. Annals Of Cardiothoracic Surgery 2013, 2: 378-86. PMID: 23977611, PMCID: PMC3741848, DOI: 10.3978/j.issn.2225-319x.2013.05.08.Peer-Reviewed Original ResearchDebranching proceduresStent graftingCardiopulmonary bypassAortic archArch vessel debranchingConventional open treatmentAortic arch diseaseTotal arch replacementEndovascular stent graftingSignificant associated morbidityAortic arch aneurysmAortic arch pathologiesCirculatory arrest timeCohort of patientsDistal landing zoneHybrid arch proceduresThoracic aortopathiesArch diseaseArch replacementArch aneurysmArch pathologiesAssociated morbidityEndovascular optionsSurgical optionsArch procedures
2012
Cerebral Protection for Aortic Arch Surgery: Deep Hypothermia
Di Luozzo G, Griepp RB. Cerebral Protection for Aortic Arch Surgery: Deep Hypothermia. Seminars In Thoracic And Cardiovascular Surgery 2012, 24: 127-130. PMID: 22920529, DOI: 10.1053/j.semtcvs.2011.12.006.Peer-Reviewed Original ResearchConceptsAortic arch surgeryArch surgeryDeep hypothermiaDeep hypothermic circulatory arrestBranched graft techniqueSelective cerebral perfusionTotal arch replacementHypothermic circulatory arrestAortic arch aneurysmArch replacementCerebral protectionArch aneurysmCerebral perfusionCirculatory arrestSurgical outcomesCardiac surgeonsGraft techniqueSurgeryHypothermiaAneurysmsPerfusionSurgeonsTechnical aspects
2010
Noninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery
Fischer GW, Lin HM, Krol M, Galati MF, Di Luozzo G, Griepp RB, Reich DL. Noninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery. Journal Of Thoracic And Cardiovascular Surgery 2010, 141: 815-821. PMID: 20579669, DOI: 10.1016/j.jtcvs.2010.05.017.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAorta, ThoracicBlood Vessel Prosthesis ImplantationCardiopulmonary BypassCirculatory Arrest, Deep Hypothermia InducedCritical CareFemaleFrontal LobeHeart Arrest, InducedHospital CostsHumansLength of StayLogistic ModelsMaleMiddle AgedMonitoring, IntraoperativeNew York CityOximetryOxygenPostoperative ComplicationsPredictive Value of TestsRespiration, ArtificialRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeConceptsRegional oxygen saturationAortic arch surgeryArch surgeryOxygen saturationOrgan dysfunctionIntensive care unit lengthRegional oxygen saturation valuesTotal aortic arch replacementPostoperative organ dysfunctionAortic arch replacementExtended hospital staySevere adverse outcomesCerebral oxygenation valuesOxygen saturation valuesArch replacementHemiarch replacementExtubation timeHospital lengthHospital stayPostoperative complicationsCerebral oximetryMinor complicationsConsiderable morbidityMajor complicationsSurgical repair
2009
Deep Hypothermic Circulatory Arrest in Patients With High Cognitive Needs: Full Preservation of Cognitive Abilities
Percy A, Widman S, Rizzo JA, Tranquilli M, Elefteriades JA. Deep Hypothermic Circulatory Arrest in Patients With High Cognitive Needs: Full Preservation of Cognitive Abilities. The Annals Of Thoracic Surgery 2009, 87: 117-123. PMID: 19101283, DOI: 10.1016/j.athoracsur.2008.10.025.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAorta, ThoracicAortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationCase-Control StudiesCirculatory Arrest, Deep Hypothermia InducedCognitionCognition DisordersFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient SatisfactionPostoperative CarePreoperative CareProbabilityPsychometricsRadiographyReference ValuesRetrospective StudiesRisk AssessmentSurveys and QuestionnairesTreatment OutcomeVascular Surgical ProceduresConceptsDeep hypothermic circulatory arrestHypothermic circulatory arrestAortic surgeryCirculatory arrestStudy groupStraight deep hypothermic circulatory arrestYale-New Haven HospitalOpen distal anastomosisThoracic aortic surgeryTotal arch replacementArch replacementCerebral protectionPreoperative statusDistal anastomosisSuch patientsFunctional outcomeControl subjectsPatientsSurgeryControl groupAdverse effectsSignificant differencesCognitive changesDaily activitiesOverall score
2008
Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study.
Nishibe T, Kondo Y, Muto A, Dardik A, Ohara Y, Kainuma M, Takeda K. Protective effect of sivelestat sodium (Eraspol) on postoperative lung dysfunction in patients with type A acute aortic dissection: a pilot study. The Journal Of Cardiovascular Surgery 2008, 49: 627-31. PMID: 18670380.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnalysis of VarianceAortic Aneurysm, ThoracicAortic DissectionCardiopulmonary BypassChi-Square DistributionFemaleGlycineHumansLeukocyte CountLung DiseasesMalePilot ProjectsPostoperative ComplicationsRespiratory Function TestsSerine Proteinase InhibitorsSulfonamidesTreatment OutcomeConceptsAcute aortic dissectionAortic arch surgeryPostoperative lung dysfunctionSivelestat sodiumAortic dissectionCardiopulmonary bypassWhite blood cellsProtective effectArch surgerySivelestat groupLung dysfunctionControl groupBlood cellsPostoperative lung injuryAortic arch replacementArterial oxygen tensionArch replacementAcute typeLung injuryPulmonary functionCirculatory arrestDeep hypothermiaInflammatory reactionPatientsF ratio
2000
Safety of left innominate vein division during aortic arch surgery
Sudhakar C, Elefteriades J. Safety of left innominate vein division during aortic arch surgery. The Annals Of Thoracic Surgery 2000, 70: 856-858. PMID: 11016323, DOI: 10.1016/s0003-4975(00)01498-3.Peer-Reviewed Original ResearchConceptsLeft innominate veinUpper extremity edemaExtremity edemaMediastinal tumorNeurologic symptomsSignificant long-term morbidityAortic arch surgeryDistal aortic anastomosisLong-term morbidityArch replacementArch surgeryExtent of involvementMultiorgan dysfunctionInnominate veinVein divisionEarly patientsMedian sternotomyAortic anastomosisMean ageSurgical approachAortic archMediastinal structuresArm elevationPatientsLocal anatomy
1993
Surgical repair of type A aortic dissection by the circulatory arrest-graft inclusion technique in sixty-six patients
Galloway A, Colvin S, Grossi E, Parish M, Culliford A, Asai T, Rofsky N, Weinreb J, Shapiro S, Baumann F, Spencer F. Surgical repair of type A aortic dissection by the circulatory arrest-graft inclusion technique in sixty-six patients. Journal Of Thoracic And Cardiovascular Surgery 1993, 105: 781-790. PMID: 8487557, DOI: 10.1016/s0022-5223(19)34151-0.Peer-Reviewed Original ResearchConceptsAortic dissectionSurgical repairDistal aneurysmsMagnetic resonance imaging (MRI) scansOverall actuarial survivalTotal arch replacementHypothermic circulatory arrestAortic valve diseaseResonance imaging scansNative aortic rootActuarial survivalArch dissectionArch replacementHemiarch repairLate deathsPreoperative shockOperative mortalityValve insertionVisceral ischemiaOperative riskCirculatory arrestValve diseaseValve repairImaging scansUnivariate analysis
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