2023
Decreased Synaptic Vesicle Glycoprotein 2A Binding in the Human Postmortem Essential Tremor Cerebellum: Evidence of Reduction in Synaptic Density
Yang Y, Zheng C, Chen B, Hernandez N, Faust P, Cai Z, Louis E, Matuskey D. Decreased Synaptic Vesicle Glycoprotein 2A Binding in the Human Postmortem Essential Tremor Cerebellum: Evidence of Reduction in Synaptic Density. The Cerebellum 2023, 23: 1053-1060. PMID: 37783917, DOI: 10.1007/s12311-023-01611-8.Peer-Reviewed Original ResearchSynaptic vesicle glycoprotein 2AAge-matched controlsSynaptic densityEssential tremorDentate nucleusCerebellar cortexET casesPilot studyLower synaptic densityPrevalent neurological diseaseNumerous degenerative changesNeuropathological alterationsMild atrophyNeuropathological studiesSynaptic markersMethodsThe current studyPostmortem studiesDegenerative changesNeuroimaging signaturesET patientsNeurological diseasesCerebellumEvidence of reductionCortexAtrophy
2022
Genetic determinants for the racial disparities in the risk of prostate and testicular cancers
Uzamere I, Wang Y, Zheng T, Zhu Y. Genetic determinants for the racial disparities in the risk of prostate and testicular cancers. Communications Medicine 2022, 2: 138. PMID: 36352009, PMCID: PMC9630379, DOI: 10.1038/s43856-022-00205-5.Peer-Reviewed Original ResearchRisk of prostateTesticular cancerProstate cancerRisk allelesRacial disparitiesEuropean ancestryAfrican ancestryMethodsThe current studyLower incidenceIncidence disparitiesHigh incidenceRisk allele frequenciesCancerConclusionsOur findingsGenetic factorsMenT-testRegression analysisProstateIncidenceGenetic determinantsCurrent studyRiskAllele frequenciesDisparities
2009
Chronic Dieting Among Extremely Obese Bariatric Surgery Candidates
Roehrig M, Masheb RM, White MA, Rothschild BS, Burke-Martindale CH, Grilo CM. Chronic Dieting Among Extremely Obese Bariatric Surgery Candidates. Obesity Surgery 2009, 19: 1116-1123. PMID: 19495894, PMCID: PMC3671950, DOI: 10.1007/s11695-009-9865-z.Peer-Reviewed Original ResearchConceptsBody mass indexBariatric surgery candidatesObese bariatric surgery candidatesSurgery candidatesBariatric candidatesPre-operative body mass indexChronic dietersHealth-related qualityWeight loss attemptsBinge-eating statusWeight-related correlatesGreater weight gainMass indexPatient groupWeight cyclingMethodsThe current studyMore episodesClinical significanceWeight historySignificant elevationSelf-report assessmentsDepressive symptomsChronic dietingGlobal functioningWeight gain
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