2025
Polygenic risk for depression and resting-state functional connectivity of subgenual anterior cingulate cortex in young adults
Chen Y, Li H, Luo X, Li G, Ide J, Li C. Polygenic risk for depression and resting-state functional connectivity of subgenual anterior cingulate cortex in young adults. Journal Of Psychiatry And Neuroscience 2025, 50: e31-e44. PMID: 39809531, PMCID: PMC11737878, DOI: 10.1503/jpn.240087.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityPolygenic risk scoresSubgenual anterior cingulate cortexAnterior cingulate cortexDepression severityCingulate cortexSubclinical depressionHealthy young adultsSomatic complaintsYoung adultsPolygenic riskAssociated with depression severitySeverity of somatic complaintsSeverity of depressive symptomsAssociated with polygenic riskWhole-brain regressionAlcohol use severityMarkers of depressionManifestations of depressionHuman Connectome ProjectDepressive disorderSubclinical populationsMode networkDepressive symptomsBrain structures
2023
Multiple trajectories of depressive symptoms among Chinese in middle and late life: Characterization and risk factors
Li C, Liu J, Ju Y, Liu B, Zhang Y. Multiple trajectories of depressive symptoms among Chinese in middle and late life: Characterization and risk factors. International Journal Of Social Psychiatry 2023, 69: 1462-1471. PMID: 37081758, DOI: 10.1177/00207640231164020.Peer-Reviewed Original ResearchConceptsDepressive symptom trajectoriesDepressive symptomsSymptom trajectoriesDepression burdenCenter for Epidemiologic Studies Depression scoreHealth statusLongitudinal associationsEpidemiological Studies Depression scoreSelf-reported health statusDevelopment of targeted prevention strategiesTrajectories of depressive symptomsRisk of mental disordersParticipants' depressive symptomsRisk factorsAssociations of baseline covariatesGeneralized Estimating EquationsAt-risk populationsAssociated with trajectoriesManifestations of depressionGrowth mixture modelingStable-lowChinese adultsStable-highDepression scoresMultinomial logistic model
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