2025
Predicting antiretroviral medication adherence among substance-using people with HIV: test and extension of the information-motivation-behavioral skills model
Krishnan A, Ranjit Y, Zhou X, Altice F. Predicting antiretroviral medication adherence among substance-using people with HIV: test and extension of the information-motivation-behavioral skills model. Journal Of Behavioral Medicine 2025, 48: 403-413. PMID: 39924604, DOI: 10.1007/s10865-025-00557-y.Peer-Reviewed Original ResearchCocaine use disorderSubstance use disordersBehavioral skillsInformation-motivation-behavioral (IMB) skills modelSkills modelInformation-motivation-behavioral skills modelAntiretroviral medication adherenceUse disorderAntiretroviral therapyART adherenceMedication adherenceDaily adherenceImprove ART adherenceMotivational barriersDisordersAntiretroviral therapy adherenceMotivational factorsPractical barriersReduce HIV transmissionEnhance ART adherenceSuboptimal adherenceVirological failureHIV transmissionCocaineAdherence
2018
High prevalence of non-adherence to antiretroviral therapy among undisclosed HIV-infected children in Ghana
Nichols JS, Kyriakides TC, Antwi S, Renner L, Lartey M, Seaneke OA, Obeng R, Catlin AC, Gan G, Reynolds NR, Paintsil E, Team O. High prevalence of non-adherence to antiretroviral therapy among undisclosed HIV-infected children in Ghana. AIDS Care 2018, 31: 25-34. PMID: 30235940, PMCID: PMC6288009, DOI: 10.1080/09540121.2018.1524113.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyART adherence ratesPediatric HIV carePrevalence of adherenceAntiretroviral medication adherenceCohort of childrenHIV-positive statusChildren of caregiversChild-caregiver dyadsHIV carePharmacy recordsRefill dataMedian adherenceMedication adherenceAdherence ratesPoor adherenceHigh prevalencePositive statusIntervention studiesHIVGood adherenceAdherenceBaseline dataChildrenTherapy
2014
Alcohol use disorders negatively influence antiretroviral medication adherence among men who have sex with men in Peru
Ferro EG, Weikum D, Vagenas P, Copenhaver MM, Gonzales P, Peinado J, Cabello R, Lama JR, Sanchez J, Altice FL. Alcohol use disorders negatively influence antiretroviral medication adherence among men who have sex with men in Peru. AIDS Care 2014, 27: 93-104. PMID: 25277252, PMCID: PMC4221495, DOI: 10.1080/09540121.2014.963013.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyART adherenceAlcohol use disorderART nonadherenceIndependent correlatesUse disordersHIV treatment engagementOnly independent correlateClinical care sitesConcentrated HIV epidemicAntiretroviral medication adherenceRecent drug useEvidence-based strategiesStandardized screening measuresAdherence surveyMedication adherenceHIV treatmentHIV epidemicCare sitesClinical careNeurocognitive impairmentMeeting criteriaSectional surveyTreatment engagementDrug use
2013
Contribution of Substance Use Disorders on HIV Treatment Outcomes and Antiretroviral Medication Adherence Among HIV-Infected Persons Entering Jail
Chitsaz E, Meyer JP, Krishnan A, Springer SA, Marcus R, Zaller N, Jordan AO, Lincoln T, Flanigan TP, Porterfield J, Altice FL. Contribution of Substance Use Disorders on HIV Treatment Outcomes and Antiretroviral Medication Adherence Among HIV-Infected Persons Entering Jail. AIDS And Behavior 2013, 17: 118-127. PMID: 23673792, PMCID: PMC3818019, DOI: 10.1007/s10461-013-0506-0.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAlcohol DrinkingAnti-Retroviral AgentsComorbidityCross-Sectional StudiesFemaleHIV InfectionsHumansLogistic ModelsMaleMedication AdherenceMiddle AgedPrisonersPrisonsSocioeconomic FactorsSubstance Abuse, IntravenousSubstance-Related DisordersTreatment OutcomeUnited StatesYoung AdultConceptsAntiretroviral medication adherenceSubstance use disordersMedication adherenceUse disordersEvidence-based drug treatmentHIV care providersHIV treatment engagementHIV treatment outcomesMedication-Assisted TherapyMulti-faceted interventionPaucity of evidenceDrug use severityAntiretroviral therapyPoor outcomePsychiatric comorbidityHIV treatmentTreatment outcomesDrug treatmentCare providersJail detaineesTreatment engagementUS sitesSubstance useVulnerable populationsUse severity
2011
Food Insecurity is Associated with Poor Virologic Response among HIV-Infected Patients Receiving Antiretroviral Medications
Wang EA, McGinnis KA, Fiellin DA, Goulet JL, Bryant K, Gibert CL, Leaf DA, Mattocks K, Sullivan LE, Vogenthaler N, Justice AC, for the VACS Project Team. Food Insecurity is Associated with Poor Virologic Response among HIV-Infected Patients Receiving Antiretroviral Medications. Journal Of General Internal Medicine 2011, 26: 1012-1018. PMID: 21573882, PMCID: PMC3157515, DOI: 10.1007/s11606-011-1723-8.Peer-Reviewed Original ResearchConceptsHIV-1 RNAHIV disease outcomeLow CD4 countAntiretroviral medicationsBody mass indexCD4 countMass indexDisease outcomeVeterans Aging Cohort StudyPoor virologic responseUnsuppressed viral loadAging Cohort StudyMultivariable logistic regressionAntiretroviral medication adherenceCross-sectional studyFood insecure participantsFood-secure participantsPotential causal associationVirologic responseVirologic suppressionCohort studyHIV diseaseHIV outcomesAdjusted analysisFood insecurity
2010
Antiretroviral medication adherence and class-specific resistance in a large prospective clinical trial
Gardner EM, Hullsiek KH, Telzak EE, Sharma S, Peng G, Burman WJ, MacArthur RD, Chesney M, Friedland G, Mannheimer SB. Antiretroviral medication adherence and class-specific resistance in a large prospective clinical trial. AIDS 2010, 24: 395-403. PMID: 20099399, PMCID: PMC2886717, DOI: 10.1097/qad.0b013e328335cd8a.Peer-Reviewed Original ResearchConceptsInitial virological failureCumulative adherenceVirological failureMedian timeNucleoside reverse transcriptase inhibitor resistanceProspective clinical trial dataInhibitor strategiesLarge prospective clinical trialsReverse transcriptase inhibitor resistanceInhibitor resistanceAntiretroviral-naive participantsProspective clinical trialsCox regression analysisTranscriptase inhibitor resistanceAntiretroviral medication adherenceProtease inhibitor resistanceClinical trial dataProtease inhibitorsMedication resistanceAntiretroviral therapyHIV RNANNRTI resistanceMedication adherenceClinical trialsGenotypic resistance
2001
Patient- and provider-reported adherence toward a clinically useful approach to measuring antiretroviral adherence
Wagner JH, Justice AC, Chesney M, Sinclair G, Weissman S, Rodriguez-Barradas M, Team F. Patient- and provider-reported adherence toward a clinically useful approach to measuring antiretroviral adherence. Journal Of Clinical Epidemiology 2001, 54: s91-s98. PMID: 11750214, DOI: 10.1016/s0895-4356(01)00450-4.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification TestViral loadProvider assessmentCurrent drug useDepressive symptomsCurrent alcohol usePatient reportsDrug useAlcohol useIndependent associationVeterans Affairs Health Care SystemPatient-reported adherenceCurrent viral loadPharmacy refill dataAntiretroviral medication adherenceEpidemiological Studies DepressionIllicit drug useDisorders Identification TestElectronic laboratory dataHealth care systemRefill dataMedication adherencePatient adherenceAntiretroviral adherenceMultivariate regression model
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