2025
The prevalence, clinical impact, and therapeutic considerations of trauma in adults with bipolar disorder: A systematic review
Xiao K, Sayed H, Xing J, Zhang X, Ai J, Teopiz K, Ho R, Rhee T, Lo H, Guillen-Burgos H, Vinberg M, McIntyre R. The prevalence, clinical impact, and therapeutic considerations of trauma in adults with bipolar disorder: A systematic review. Journal Of Affective Disorders 2025, 119507. PMID: 40449746, DOI: 10.1016/j.jad.2025.119507.Peer-Reviewed Original ResearchBipolar disorderSevere stressful life eventsChildhood emotional maltreatmentChildhood physical maltreatmentStressful life eventsEffects of traumaImpact of traumaChildhood traumaClinical impactEmotional maltreatmentSymptom severityLife eventsPhysical maltreatmentTherapeutic considerationsIllness severityIntegrated model of careModerating effectTreatment responseTreatment outcomesSystematic reviewAssociated with poor prognosisMaltreatmentModality of treatmentNegative clinical impactHistory of trauma
2024
Breaking the cycle with trauma-focused mentalization-based treatment: theory and practice of a trauma-focused group intervention
Smits M, de Vos J, Rüfenacht E, Nijssens L, Shaverin L, Nolte T, Luyten P, Fonagy P, Bateman A. Breaking the cycle with trauma-focused mentalization-based treatment: theory and practice of a trauma-focused group intervention. Frontiers In Psychology 2024, 15: 1426092. PMID: 39346509, PMCID: PMC11427379, DOI: 10.3389/fpsyg.2024.1426092.Peer-Reviewed Original ResearchMentalization-based treatmentImpact of traumaAdaptations of MBTGroup interventionBorderline personality pathologyTrauma-focused group interventionAttachment behavioral systemNegative perceptions of selfImpaired mental abilityClinical case examplesEffects of traumaPerceptions of selfPersonality pathologyAttachment traumaMental abilityMental perspectiveComplex traumaAvoidance behaviorEpistemic trustRelational difficultiesDissociative experiencesBehavioral systemsTreatment phaseCase examplePost-trauma
2020
Exploring the impact of trauma type and extent of exposure on posttraumatic alterations in 5-HT1A expression
Lewis M, Jones R, Davis M. Exploring the impact of trauma type and extent of exposure on posttraumatic alterations in 5-HT1A expression. Translational Psychiatry 2020, 10: 237. PMID: 32678079, PMCID: PMC7366706, DOI: 10.1038/s41398-020-00915-1.Peer-Reviewed Original ResearchConceptsTrauma typesTrauma exposureImpact of trauma typeExposure to potentially traumatic eventsSerotonin 1 A receptorExpression of 5-HT1AImpact of trauma exposureTrauma-exposed individualsRegulating serotonin releasePotentially traumatic eventsG protein-coupled serotonin receptorsImpact of traumaNeurobiological impactNeurobiological effectsHTR1A genePsychiatric syndromesEmotional behaviorPsychiatric symptomsStress respondingSerotonin receptorsTraumatic eventsSerotonin releaseExtent of exposureHuman literatureTrauma-induced changes
2012
Posttraumatic Stress Symptoms and Life Functioning in Older Female Ex-Prisoners of War
Walser R, Tran C, Cook J. Posttraumatic Stress Symptoms and Life Functioning in Older Female Ex-Prisoners of War. Psychological Trauma Theory Research Practice And Policy 2012, 4: 466-468. DOI: 10.1037/a0027490.Peer-Reviewed Original ResearchCurrent PTSD symptomsVeterans Affairs primary care clinicsPTSD symptomsPrimary care clinicsMajority of womenAppropriate health careCross-sectional surveyDiagnosis of PTSDCare clinicsOutcome measuresLong-term effectsPosttraumatic stress symptomsNumber of womenTrauma exposureSame cohortSymptomsWomenHealth careSignificant differencesImpact of traumaStressful experiencesStress symptomsStressful eventsPTSD
2010
Agreement of Parent and Child Reports of Trauma Exposure and Symptoms in the Early Aftermath of a Traumatic Event
Stover CS, Hahn H, Berkowitz S, Im J. Agreement of Parent and Child Reports of Trauma Exposure and Symptoms in the Early Aftermath of a Traumatic Event. Psychological Trauma Theory Research Practice And Policy 2010, 2: 159-168. PMID: 21572906, PMCID: PMC3093053, DOI: 10.1037/a0019156.Peer-Reviewed Original ResearchChild reportsPsychological functioningTraumatic eventsChildren's psychological functioningChild trauma historyImpact of traumaAgreement of parentsChild distressTrauma exposurePTSD symptomsTraumatic exposureHyperarousal symptomsTrauma historyParental acknowledgementSubjective reportsNon-significant agreementEarly aftermathPhysical assaultEarly interventionCommon experienceParentsDistressChildrenSerious accidentsPTSD
2009
Noradrenergic and serotonergic mechanisms in the neurobiology of posttraumatic stress disorder and resilience
Krystal JH, Neumeister A. Noradrenergic and serotonergic mechanisms in the neurobiology of posttraumatic stress disorder and resilience. Brain Research 2009, 1293: 13-23. PMID: 19332037, PMCID: PMC2761677, DOI: 10.1016/j.brainres.2009.03.044.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderStress disorderOrdinary stressful life eventsEtiology of PTSDNeurobiology of PTSDSymptoms of PTSDImpact of traumaStressful life eventsTraumatic eventsNeurobiological systemsLife eventsTreatment developmentSerotonergic mechanismsNeurobiologyUse of antidepressantsDevelopment of treatmentsBasic researchResilienceMonoaminergic mechanismsAvailable treatmentsRelevant findingsHyperarousalResearchDisordersPsychopathology
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