2021
Long-Term Kidney Outcomes Following Dialysis-Treated Childhood Acute Kidney Injury: A Population-Based Cohort Study
Robinson CH, Jeyakumar N, Luo B, Wald R, Garg AX, Nash DM, McArthur E, Greenberg J, Askenazi D, Mammen C, Thabane L, Goldstein S, Parekh RS, Zappitelli M, Chanchlani R. Long-Term Kidney Outcomes Following Dialysis-Treated Childhood Acute Kidney Injury: A Population-Based Cohort Study. Journal Of The American Society Of Nephrology 2021, 32: 2005-2019. PMID: 34039667, PMCID: PMC8455253, DOI: 10.1681/asn.2020111665.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAdolescentCase-Control StudiesChildChild, PreschoolFemaleFollow-Up StudiesHumansHypertensionIncidenceInfantInfant, NewbornKidney Failure, ChronicMaleMortalityOntarioProportional Hazards ModelsRenal DialysisRenal Insufficiency, ChronicRetrospective StudiesRisk FactorsSurvivorsTime FactorsConceptsAKI survivorsKidney failureLong-term riskCohort studyCox proportional hazards regression analysisAdverse short-term outcomesChildhood acute kidney injuryProportional hazards regression analysisHigher long-term riskAcute kidney injuryHealth administrative databasesRetrospective cohort studyHazards regression analysisShort-term outcomesLong-term outcomesBasis of ageAKI episodesPediatric AKISubsequent AKIKidney injuryComposite outcomeCardiac surgeryHospitalized cohortMechanical ventilationPediatric hospitalizations
2017
Acute Kidney Injury in Cirrhosis: Baseline Serum Creatinine Predicts Patient Outcomes
Wong F, O'Leary J, Reddy K, Garcia-Tsao G, Fallon M, Biggins S, Subramanian R, Thuluvath P, Kamath P, Patton H, Maliakkal B, Tandon P, Vargas H, Thacker L, Bajaj J. Acute Kidney Injury in Cirrhosis: Baseline Serum Creatinine Predicts Patient Outcomes. The American Journal Of Gastroenterology 2017, 112: 1103. PMID: 28440305, DOI: 10.1038/ajg.2017.122.Peer-Reviewed Original ResearchConceptsAcute kidney injuryBaseline serum creatinineHigher baseline serum creatinineInternational Ascites ClubSerum creatinineDelta serum creatinineAKI outcomesKidney injuryPatient outcomesDevelopment of AKIIncidence of AKIStage 1 acute kidney injuryTertiary-care hepatology centersEnd-stage liver diseaseBaseline SCr levelPeak serum creatinineMultivariate logistic regressionNorth American ConsortiumAKI episodesAKI progressionAKI riskCirrhotic inpatientsHepatology centersCirrhotic patientsSCr levels
2013
New Consensus Definition of Acute Kidney Injury Accurately Predicts 30-Day Mortality in Patients With Cirrhosis and Infection
Wong F, O'Leary JG, Reddy KR, Patton H, Kamath PS, Fallon MB, Garcia–Tsao G, Subramanian RM, Malik R, Maliakkal B, Thacker LR, Bajaj JS, Disease N. New Consensus Definition of Acute Kidney Injury Accurately Predicts 30-Day Mortality in Patients With Cirrhosis and Infection. Gastroenterology 2013, 145: 1280-1288.e1. PMID: 23999172, PMCID: PMC4418483, DOI: 10.1053/j.gastro.2013.08.051.Peer-Reviewed Original ResearchConceptsAcute kidney injuryDays of hospitalizationKidney injuryOrgan failureConsensus definitionHigher Child-Pugh scoreIrreversible acute kidney injuryChild-Pugh scoreHigh MELD scoreSerum creatinine levelsMean arterial pressureIntensive care unitLength of stayNew consensus definitionStable baseline valuesAKI episodesRenal recoveryHospital stayMELD scoreCreatinine levelsArterial pressureCare unitProspective studyBaseline valuesConsensus conference
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