2024
When Perfect Is the Enemy of Good: Results of a RAND Appropriateness Panel on Treat to Target in Asymptomatic Inflammatory Bowel Disease
Systrom H, Rai V, Singh S, Baidoo L, Cheifetz A, Devlin S, Gecse K, Irving P, Kaplan G, Kozuch P, Ullman T, Sparrow M, Melmed G, Siegel C. When Perfect Is the Enemy of Good: Results of a RAND Appropriateness Panel on Treat to Target in Asymptomatic Inflammatory Bowel Disease. The American Journal Of Gastroenterology 2024, 120: 420-430. PMID: 39008539, DOI: 10.14309/ajg.0000000000002964.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseAsymptomatic patientsChanging therapyStable diseaseEndoscopic remissionEndoscopic activityBowel diseaseAsymptomatic inflammatory bowel diseaseRAND/University of California Los Angeles Appropriateness MethodTreat-to-target strategyActive endoscopic diseaseUlcerative colitis patientsCrohn's disease patientsLos Angeles Appropriateness MethodExtensive diseaseDisease extentPatient ageAphthous ulcersRandomized studyEndoscopic diseaseClinical decision-makingColitis patientsAdvanced therapiesTreatment adjustmentAnonymous survey
2020
Use of Fecal Occult Blood Testing as a Diagnostic Tool for Clinical Indications: A Systematic Review and Meta-Analysis.
Lee MW, Pourmorady JS, Laine L. Use of Fecal Occult Blood Testing as a Diagnostic Tool for Clinical Indications: A Systematic Review and Meta-Analysis. The American Journal Of Gastroenterology 2020, 115: 662-670. PMID: 31972617, DOI: 10.14309/ajg.0000000000000495.Peer-Reviewed Original ResearchConceptsFecal occult blood testIron deficiency anemiaSensitivity of FOBTAcute diarrheaClinical indicationsSystematic reviewFecal occult blood testingDiagnostic testsSpecific gastrointestinal symptomsOccult blood testingPrimary end pointOccult blood testColorectal cancer screeningPositive stool cultureRisk of biasQUADAS-2 toolGastrointestinal symptomsAdult patientsEndoscopic evaluationUlcerative colitisEndoscopic activityBlood testsIdentifiable causeStool culturesBlood testing
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