2025
Utilization and Fertility Preservation Outcomes in Women Undergoing Embryo Cryopreservation Before Breast Cancer Treatment: A Meta-Analysis
Turan V, Oktem O, Bang H, Oktay K. Utilization and Fertility Preservation Outcomes in Women Undergoing Embryo Cryopreservation Before Breast Cancer Treatment: A Meta-Analysis. Clinical Breast Cancer 2025, 25: 617-624.e1. PMID: 40603132, DOI: 10.1016/j.clbc.2025.06.003.Peer-Reviewed Original ResearchBreast cancer treatmentFertility preservation rateLive birth rateClinical pregnancyCancer treatmentFertility preservationEmbryo transferPreservation rateBirth rateFertility preservation outcomesFrozen embryo transferCochrane Library databasesRandom-effects modelSecondary outcome measuresPregnancy outcomesEmbryo cryopreservationBreast cancerPreservation outcomesLibrary databasesPregnancyBreastMeta-analysisOutcome measuresWomenTreatmentCurrent Practices in Fertility-Based Counseling Among Individuals With Turner Syndrome: A Retrospective Study
Beroukhim G, Kastury R, Davidson K, Bergmann J, Vash-Margita A. Current Practices in Fertility-Based Counseling Among Individuals With Turner Syndrome: A Retrospective Study. Journal Of Pediatric And Adolescent Gynecology 2025, 38: 474-480. PMID: 39922296, DOI: 10.1016/j.jpag.2025.02.002.Peer-Reviewed Original ResearchAutologous assisted reproductive technologyFP counselingTurner syndromeMonosomy XFertility preservationControlled ovarian hyperstimulationReceipt of counselingCardiac anomaliesAssisted Reproductive TechnologyRetrospective studyFertility counselingOvarian hyperstimulationOocyte cryopreservationEmbryo cryopreservationLow bone densityReproductive technologyGroup of providersIndividuals aged 0TS karyotypeCounselingBone densityCohort studyMonosomyEvaluate current practiceMultidisciplinary group of providers
2020
Embryo cryopreservation and utilization in the United States from 2004–2013
Christianson MS, Stern JE, Sun F, Zhang H, Styer AK, Vitek W, Polotsky AJ. Embryo cryopreservation and utilization in the United States from 2004–2013. F&S Reports 2020, 1: 71-77. PMID: 34223221, PMCID: PMC8244341, DOI: 10.1016/j.xfre.2020.05.010.Peer-Reviewed Original ResearchART cyclesFresh cyclesAssisted Reproductive Technology Clinical Outcomes Reporting SystemEmbryo transferSubsequent frozen embryo transferDonor oocyte cyclesAntimüllerian hormone levelsDiminished ovarian reserveFrozen embryo transferReproductive technology clinicsPreimplantation genetic testingAssisted Reproductive TechnologyNumber of embryosPercentage of womenOocyte cyclesOvarian reserveHistorical cohortHormone levelsRegistry dataRetrospective analysisTechnology clinicsGenetic testingExcess embryosEmbryo cryopreservationFrozen embryos
2018
Transfer of Fresh versus Frozen Embryos in Ovulatory Women
Shi Y, Sun Y, Hao C, Zhang H, Wei D, Zhang Y, Zhu Y, Deng X, Qi X, Li H, Ma X, Ren H, Wang Y, Zhang D, Wang B, Liu F, Wu Q, Wang Z, Bai H, Li Y, Zhou Y, Sun M, Liu H, Li J, Zhang L, Chen X, Zhang S, Sun X, Legro R, Chen Z. Transfer of Fresh versus Frozen Embryos in Ovulatory Women. New England Journal Of Medicine 2018, 378: 126-136. PMID: 29320646, DOI: 10.1056/nejmoa1705334.Peer-Reviewed Original ResearchConceptsFresh embryo transferFrozen embryo transferLive birth rateOvarian hyperstimulation syndromeHyperstimulation syndromeElective frozen embryo transferOvulatory womenFrozen-embryo groupFresh embryo groupIn vitro fertilization cyclesHigher live birth ratesPolycystic ovary syndromeRate of implantsCleavage-stage embryosOverall pregnancy lossAnovulatory womenNeonatal complicationsClinical pregnancyOngoing pregnancyFrozen embryosEmbryo cryopreservationBetween-group differencesEmbryo transferLive birthsFertilization cycles
2016
Tissue recovery and in vitro maturation of immature oocytes as a fertility preservation strategy for tandem ovarian, oocyte, and embryo cryopreservation
Sugishita Y, Suzuki N, Moy F, Oktay K. Tissue recovery and in vitro maturation of immature oocytes as a fertility preservation strategy for tandem ovarian, oocyte, and embryo cryopreservation. Fertility And Sterility 2016, 106: e54. DOI: 10.1016/j.fertnstert.2016.07.166.Peer-Reviewed Original ResearchEmbryo Cryopreservation in Breast Cancer Patients
Bedoschi G, Oktay K. Embryo Cryopreservation in Breast Cancer Patients. 2016, 39-52. DOI: 10.1007/978-4-431-55963-4_3.Peer-Reviewed Original ResearchBreast cancer patientsCancer patientsFertility preservationEmbryo cryopreservationAdjuvant systemic chemotherapyFertility preservation techniquesOvarian stimulation protocolsBreast cancer casesOvarian stimulationSystemic chemotherapyOvarian reserveIncident casesAromatase inhibitorsBreast cancerCancer casesStimulation protocolPatientsDonor semenCommon typeWomenFuture reproductive potentialCancerPreservation techniquesAttractive strategySpecial consideration
2015
Knowledge of ovarian reserve and reproductive choices
Azhar E, Seifer DB, Melzer K, Ahmed A, Weedon J, Minkoff H. Knowledge of ovarian reserve and reproductive choices. Journal Of Assisted Reproduction And Genetics 2015, 32: 409-415. PMID: 25596723, PMCID: PMC4363241, DOI: 10.1007/s10815-014-0415-9.Peer-Reviewed Original ResearchConceptsHealth care professionalsOvarian reserveCare professionalsMale health care professionalsMethodA cross-sectional surveyReproductive-age womenCross-sectional surveyLifestyle changesOocyte cryopreservationAnonymous questionnaireMarital statusEmbryo cryopreservationReproductive choicesNormal patternChildrenReproductive declineProfessionalsObjectiveToReproductive reservesPhysiciansDemographicsWomen
2014
Live birth after fresh embryo transfer vs elective embryo cryopreservation/frozen embryo transfer in women with polycystic ovary syndrome undergoing IVF (FreFro-PCOS): study protocol for a multicenter, prospective, randomized controlled clinical trial
Shi Y, Wei D, Liang X, Sun Y, Liu J, Cao Y, Zhang B, Legro RS, Zhang H, Chen ZJ. Live birth after fresh embryo transfer vs elective embryo cryopreservation/frozen embryo transfer in women with polycystic ovary syndrome undergoing IVF (FreFro-PCOS): study protocol for a multicenter, prospective, randomized controlled clinical trial. Trials 2014, 15: 154. PMID: 24885793, PMCID: PMC4022358, DOI: 10.1186/1745-6215-15-154.Peer-Reviewed Original ResearchConceptsFrozen-thawed embryo transferElective embryo cryopreservationFresh embryo transferLive birth rateEmbryo transferPCOS patientsPregnancy complicationsOocyte retrievalClinical trialsEmbryo cryopreservationMethods/designThis studyInfertile PCOS patientsClinical pregnancy ratePolycystic ovary syndromeFrozen embryo transferIntracytoplasmic sperm injectionBirth rateOvary syndromePregnancy outcomesPrimary outcomeAbnormal implantationPregnancy lossParallel groupPregnancy rateGroup B
2010
In vitro maturation improves oocyte or embryo cryopreservation outcome in breast cancer patients undergoing ovarian stimulation for fertility preservation
Oktay K, Buyuk E, Rodriguez-Wallberg K, Sahin G. In vitro maturation improves oocyte or embryo cryopreservation outcome in breast cancer patients undergoing ovarian stimulation for fertility preservation. Reproductive BioMedicine Online 2010, 20: 634-638. PMID: 20219430, DOI: 10.1016/j.rbmo.2010.01.012.Peer-Reviewed Original ResearchConceptsBreast cancer patientsMature oocyte yieldCancer patientsOvarian stimulationOocyte yieldFertility preservationFertility preservation cyclesMature oocytesCryopreservation cyclesTotal numberSecondary analysisVitro maturationImmature oocytesPatientsIVMEmbryo cryopreservationFertilization rateOocytesStimulationUseful strategyMaturationChemotherapy
2005
Oocyte and Ovarian Tissue Cryopreservation: Indications, Techniques, and Applications
Shamonki M, Oktay K. Oocyte and Ovarian Tissue Cryopreservation: Indications, Techniques, and Applications. Seminars In Reproductive Medicine 2005, 23: 266-276. PMID: 16059833, DOI: 10.1055/s-2005-872455.Peer-Reviewed Original ResearchLetrozole and tamoxifen as safer ovarian stimulants in women undergoing embryo cryopreservation for fertility preservation before breast cancer chemotherapy: A prospective controlled trial
Oktay K, Libertella N, Buyuk E, Lostritto K, Vickers A, Akar M. Letrozole and tamoxifen as safer ovarian stimulants in women undergoing embryo cryopreservation for fertility preservation before breast cancer chemotherapy: A prospective controlled trial. Journal Of Clinical Oncology 2005, 23: 539-539. DOI: 10.1200/jco.2005.23.16_suppl.539.Peer-Reviewed Original ResearchFertility preservation options for female patients with malignancies
Seli E, Tangir J. Fertility preservation options for female patients with malignancies. Current Opinion In Obstetrics & Gynecology 2005, 17: 299-308. PMID: 15870565, DOI: 10.1097/01.gco.0000169108.15623.34.Peer-Reviewed Original ResearchConceptsFemale patientsFertility preservationOocyte cryopreservationOvarian tissueGonadotropin-releasing hormone agonistRadical vaginal trachelectomyInitiation of chemotherapyFertility preservation optionsOvarian stimulation protocolsPreservation of fertilityCryopreserved ovarian tissueFirst embryo transferEmbryo cryopreservationImportant health issueVaginal trachelectomyConservative surgeryGynecologic malignanciesEndometrial cancerOvarian cryopreservationHormone agonistCervical cancerFirst pregnancyProgestin treatmentOvarian tumorsOrthotopic transplantation
2004
Fertility preservation in breast cancer patients: A prospective controlled comparison of ovarian stimulation with tamoxifen and letrozole for embryo cryopreservation
Oktay K, Buyuk E, Akar M, Rosenwaks Z, Libertella N. Fertility preservation in breast cancer patients: A prospective controlled comparison of ovarian stimulation with tamoxifen and letrozole for embryo cryopreservation. Fertility And Sterility 2004, 82: s1. DOI: 10.1016/j.fertnstert.2004.07.007.Peer-Reviewed Original Research
2003
Novel use of an aromatase inhibitor for fertility preservation via embryo cryopreservation in endometrial cancer: a case report
Oktay K, Buyuk E, Rosenwaks Z. Novel use of an aromatase inhibitor for fertility preservation via embryo cryopreservation in endometrial cancer: a case report. Fertility And Sterility 2003, 80: 144. DOI: 10.1016/s0015-0282(03)01261-5.Peer-Reviewed Original ResearchEndometrial cancerFertility preservationCase reportAromatase inhibitorsEmbryo cryopreservationCancer
2002
Fertility preservation in breast cancer patients: In vitro fertilization and embryo cryopreservation after ovarian stimulation with tamoxifen
Oktay K, Buyuk E, Davis O, Rosenwaks Z. Fertility preservation in breast cancer patients: In vitro fertilization and embryo cryopreservation after ovarian stimulation with tamoxifen. Fertility And Sterility 2002, 78: s80. DOI: 10.1016/s0015-0282(02)03591-4.Peer-Reviewed Original Research
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