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2025

Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder
Strom N, Gerring Z, Galimberti M, Yu D, Halvorsen M, Abdellaoui A, Rodriguez-Fontenla C, Sealock J, Bigdeli T, Coleman J, Mahjani B, Thorp J, Bey K, Burton C, Luykx J, Zai G, Alemany S, Andre C, Askland K, Bäckman J, Banaj N, Barlassina C, Nissen J, Bienvenu O, Black D, Bloch M, Børte S, Bosch R, Breen M, Brennan B, Brentani H, Buxbaum J, Bybjerg-Grauholm J, Byrne E, Cabana-Dominguez J, Camarena B, Camarena A, Cappi C, Carracedo A, Casas M, Cavallini M, Ciullo V, Cook E, Crosby J, Cullen B, De Schipper E, Delorme R, Djurovic S, Elias J, Estivill X, Falkenstein M, Fundin B, Garner L, Gironda C, Goes F, Grados M, Grove J, Guo W, Haavik J, Hagen K, Harrington K, Havdahl A, Höffler K, Hounie A, Hucks D, Hultman C, Janecka M, Jenike E, Karlsson E, Kelley K, Klawohn J, Krasnow J, Krebs K, Lange C, Lanzagorta N, Levey D, Lindblad-Toh K, Macciardi F, Maher B, Mathes B, McArthur E, McGregor N, McLaughlin N, Meier S, Miguel E, Mulhern M, Nestadt P, Nurmi E, O’Connell K, Osiecki L, Ousdal O, Palviainen T, Pedersen N, Piras F, Piras F, Potluri S, Rabionet R, Ramirez A, Rauch S, Reichenberg A, Riddle M, Ripke S, Rosário M, Sampaio A, Schiele M, Skogholt A, Sloofman L, Smit J, Artigas M, Thomas L, Tifft E, Vallada H, van Kirk N, Veenstra-VanderWeele J, Vulink N, Walker C, Wang Y, Wendland J, Winsvold B, Yao Y, Zhou H, Agrawal A, Alonso P, Berberich G, Bucholz K, Bulik C, Cath D, Denys D, Eapen V, Edenberg H, Falkai P, Fernandez T, Fyer A, Gaziano J, Geller D, Grabe H, Greenberg B, Hanna G, Hickie I, Hougaard D, Kathmann N, Kennedy J, Lai D, Landén M, Hellard S, Leboyer M, Lochner C, McCracken J, Medland S, Mortensen P, Neale B, Nicolini H, Nordentoft M, Pato M, Pato C, Pauls D, Piacentini J, Pittenger C, Posthuma D, Ramos-Quiroga J, Rasmussen S, Richter M, Rosenberg D, Ruhrmann S, Samuels J, Sandin S, Sandor P, Spalletta G, Stein D, Stewart S, Storch E, Stranger B, Turiel M, Werge T, Andreassen O, Børglum A, Walitza S, Hveem K, Hansen B, Rück C, Martin N, Milani L, Mors O, Reichborn-Kjennerud T, Ribasés M, Kvale G, Mataix-Cols D, Domschke K, Grünblatt E, Wagner M, Zwart J, Breen G, Nestadt G, Kaprio J, Arnold P, Grice D, Knowles J, Ask H, Verweij K, Davis L, Smit D, Crowley J, Scharf J, Stein M, Gelernter J, Mathews C, Derks E, Mattheisen M. Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder. Nature Genetics 2025, 57: 1389-1401. PMID: 40360802, PMCID: PMC12165847, DOI: 10.1038/s41588-025-02189-z.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Translational genomics of osteoarthritis in 1,962,069 individuals
Hatzikotoulas K, Southam L, Stefansdottir L, Boer C, McDonald M, Pett J, Park Y, Tuerlings M, Mulders R, Barysenka A, Arruda A, Tragante V, Rocco A, Bittner N, Chen S, Horn S, Srinivasasainagendra V, To K, Katsoula G, Kreitmaier P, Tenghe A, Gilly A, Arbeeva L, Chen L, de Pins A, Dochtermann D, Henkel C, Höijer J, Ito S, Lind P, Lukusa-Sawalena B, Minn A, Mola-Caminal M, Narita A, Nguyen C, Reimann E, Silberstein M, Skogholt A, Tiwari H, Yau M, Yue M, Zhao W, Zhou J, Alexiadis G, Banasik K, Brunak S, Campbell A, Cheung J, Dowsett J, Faquih T, Faul J, Fei L, Fenstad A, Funayama T, Gabrielsen M, Gocho C, Gromov K, Hansen T, Hudjashov G, Ingvarsson T, Johnson J, Jonsson H, Kakehi S, Karjalainen J, Kasbohm E, Lemmelä S, Lin K, Liu X, Loef M, Mangino M, McCartney D, Millwood I, Richman J, Roberts M, Ryan K, Samartzis D, Shivakumar M, Skou S, Sugimoto S, Suzuki K, Takuwa H, Teder-Laving M, Thomas L, Tomizuka K, Turman C, Weiss S, Wu T, Zengini E, Zhang Y, Ferreira M, Babis G, Baras A, Barker T, Carey D, Cheah K, Chen Z, Cheung J, Daly M, de Mutsert R, Eaton C, Erikstrup C, Furnes O, Golightly Y, Gudbjartsson D, Hailer N, Hayward C, Hochberg M, Homuth G, Huckins L, Hveem K, Ikegawa S, Ishijima M, Isomura M, Jones M, Kang J, Kardia S, Kloppenburg M, Kraft P, Kumahashi N, Kuwata S, Lee M, Lee P, Lerner R, Li L, Lietman S, Lotta L, Lupton M, Mägi R, Martin N, McAlindon T, Medland S, Michaëlsson K, Mitchell B, Mook-Kanamori D, Morris A, Nabika T, Nagami F, Nelson A, Ostrowski S, Palotie A, Pedersen O, Rosendaal F, Sakurai-Yageta M, Schmidt C, Sham P, Singh J, Smelser D, Smith J, Song Y, Sørensen E, Tamiya G, Tamura Y, Terao C, Thorleifsson G, Troelsen A, Tsezou A, Uchio Y, Uitterlinden A, Ullum H, Valdes A, van Heel D, Walters R, Weir D, Wilkinson J, Winsvold B, Yamamoto M, Zwart J, Stefansson K, Meulenbelt I, Teichmann S, van Meurs J, Styrkarsdottir U, Zeggini E. Translational genomics of osteoarthritis in 1,962,069 individuals. Nature 2025, 641: 1217-1224. PMID: 40205036, PMCID: PMC12119359, DOI: 10.1038/s41586-025-08771-z.
Peer-Reviewed Original Research
MeSH Keywords and Concepts