2024
P- 40 PENTOXIFYLLINE USE IN PATIENTS WITH ALCOHOL-ASSOCIATED HEPATITIS ADMITTED WITH ACUTE KIDNEY INJURY COULD DECREASE SURVIVAL: A GLOBAL STUDY
Idalsoaga F, Diaz L, Corsi O, Ayares G, Arnold J, Dunn W, Li Y, Singal A, Simonetto D, Ayala-Valverde M, Ramirez C, Morales-Arraez D, Zhang W, Qian S, Ahn J, Buryska S, Mehta H, Waleed M, Stefanescu H, Horhat A, Bumbu A, Agrawal B, Agrawal R, Cabezas J, Cuyàs B, Poca M, Pastor G, Sarin S, Maiwall R, Jalal P, La Tijera M, Kulkarni A, Rao N, Salazar P, Skladaný L, Bystrianska N, Prado V, Clemente-Sanchez A, Rincón D, Haider T, Chacko K, Romero G, Pollarsky F, Restrepo J, Toro L, Yaquich P, Mendizabal M, Garrido M, Marciano S, Dirchwolf M, Vargas V, Jimenez C, García-Tsao G, Ortiz G, Abraldes J, Kamath P, Shah V, Bataller R, Arab J. P- 40 PENTOXIFYLLINE USE IN PATIENTS WITH ALCOHOL-ASSOCIATED HEPATITIS ADMITTED WITH ACUTE KIDNEY INJURY COULD DECREASE SURVIVAL: A GLOBAL STUDY. Annals Of Hepatology 2024, 29: 101227. DOI: 10.1016/j.aohep.2023.101227.Peer-Reviewed Original ResearchAlcohol-associated hepatitisAcute kidney injurySevere AHPentoxifylline useLiver transplantationKidney injuryMaddrey's discriminant functionAssociated with increased mortalityHistory of cirrhosisSubgroup of patientsRetrospective cohort studyMultivariate-adjusted modelsEffect of pentoxifyllineAssociated with mortalityCompeting-risks modelMedian ageSerum creatinineMELD scoreUnivariate analysisCohort studyFemale sexPentoxifyllineDecreased survivalSevere entityPatients
2018
Racial Disparities and Sociodemographic Differences in Incidence and Survival Among Pediatric Patients in the United States With Primary Liver Cancer
Nautsch F, Ludwig J, Xing M, Johnson K, Kim H. Racial Disparities and Sociodemographic Differences in Incidence and Survival Among Pediatric Patients in the United States With Primary Liver Cancer. Journal Of Clinical Gastroenterology 2018, 52: 262-267. PMID: 28617762, DOI: 10.1097/mcg.0000000000000833.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsBlack or African AmericanCarcinoma, HepatocellularChildChild, PreschoolFemaleHealth Services AccessibilityHealth Status DisparitiesHepatoblastomaHumansIncidenceInfantInfant, NewbornLiver NeoplasmsMaleProportional Hazards ModelsRacial GroupsSEER ProgramSurvival RateTime FactorsUnited StatesWhite PeopleYoung AdultConceptsPrimary liver cancerOverall survivalHepatocellular carcinomaAfrican American childrenPediatric patientsLiver cancerEnd Results cancer registry dataUniversal health care accessAmerican childrenCancer registry dataHealth care accessTreatment-related informationAge of diagnosisFactors affecting outcomePopulation database studyCare accessSociodemographic differencesMedian ageRacial disparitiesRegistry dataPediatric populationHepatoblastomaDecreased survivalPatientsDatabase study
2015
Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer
Neskey DM, Osman AA, Ow TJ, Katsonis P, McDonald T, Hicks SC, Hsu TK, Pickering CR, Ward A, Patel A, Yordy JS, Skinner HD, Giri U, Sano D, Story MD, Beadle BM, El-Naggar AK, Kies MS, William WN, Caulin C, Frederick M, Kimmel M, Myers JN, Lichtarge O. Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer. Cancer Research 2015, 75: 1527-1536. PMID: 25634208, PMCID: PMC4383697, DOI: 10.1158/0008-5472.can-14-2735.Peer-Reviewed Original ResearchConceptsTP53 mutationsDistant metastasisP53 mutationsNeck squamous cell carcinomaSquamous cell carcinomaPoor survival outcomesAggressive tumor behaviorEvolutionary action scoreHigh-risk mutationsLung metastasesPrognostic significanceSurvival outcomesCell carcinomaNeck cancerClinical prognosisHigh incidenceLower riskTumor behaviorDecreased survivalKey cellular pathwaysTumor cellsMetastasisRisk mutationsPatientsTumors
2011
Decreased Survival Of Idiopathic Pulmonary Fibrosis Patients With Heat Shock Protein 70 Autoreactivity
Xue J, Kahloon R, Bhargava A, Banga G, Gochuico B, Dacic S, Gibson K, Kaminski N, Sciurba F, Rosas I, Otterbein L, Zhang Y, Duncan S. Decreased Survival Of Idiopathic Pulmonary Fibrosis Patients With Heat Shock Protein 70 Autoreactivity. 2011, a4275-a4275. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4275.Peer-Reviewed Original Research
2010
Elevated plasma tissue inhibitor of metalloproteinase‐1 levels predict decreased survival in castration‐resistant prostate cancer patients
Oh W, Vargas R, Jacobus S, Leitzel K, Regan M, Hamer P, Pierce K, Brown‐Shimer S, Carney W, Ali S, Kantoff P, Lipton A. Elevated plasma tissue inhibitor of metalloproteinase‐1 levels predict decreased survival in castration‐resistant prostate cancer patients. Cancer 2010, 117: 517-525. PMID: 20862742, DOI: 10.1002/cncr.25394.Peer-Reviewed Original ResearchConceptsTIMP-1 levelsPlasma TIMP-1 levelsTIMP-1Overall survivalProstate cancerElevated plasma TIMP-1 levelsMetastatic castration-resistant PC patientsCastration-resistant prostate cancer patientsEastern Cooperative Oncology Group performance statusTissue inhibitorCastration-resistant prostate cancerDecreased survivalElevated TIMP-1 levelsCatalytic activity of matrix metalloproteinasesPlasma TIMP-1Castration-resistant PCMedian Follow-UpProstate-specific antigenKaplan-Meier methodPlasma tissue inhibitorProstate cancer patientsActivity of matrix metalloproteinasesCox regression modelsPromotion of angiogenesisEnzyme-linked immunosorbent assay
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