2025
Sex-specific effects of exogenous asparagine on colorectal tumor growth, 17β-estradiol levels, and aromatase
Aladelokun O, Benitez K, Wang Y, Jain A, Berardi D, Maroun G, Shen X, Roper J, Gibson J, Sumigray K, Khan S, Johnson C. Sex-specific effects of exogenous asparagine on colorectal tumor growth, 17β-estradiol levels, and aromatase. Pharmacological Research 2025, 215: 107736. PMID: 40228761, PMCID: PMC12100670, DOI: 10.1016/j.phrs.2025.107736.Peer-Reviewed Original ResearchTumor-specific survivalColorectal cancerTumor growthR2G2 miceIncreased serum estradiol levelsSerum estradiol levelsSub-populations of macrophagesAssociated with cancer prognosisSuppressed tumor growthColorectal tumor growthExogenous asparagineColorectal cancer developmentColorectal cancer cellsNegative feed-back effectEstradiol levelsGlutamate levelsSex-related differencesSex-specific effectsMale miceCancer prognosisAsparagine supplementationCancer progressionMiceDecreased numberTumor
2024
Decision-making in women who considered planned oocyte cryopreservation: decision satisfaction or regret?
Korkidakis A, Martinez S, Sabbagh R, Heyward Q, Sakkas D, Domar A, Toth T. Decision-making in women who considered planned oocyte cryopreservation: decision satisfaction or regret? Reproductive BioMedicine Online 2024, 50: 103944. PMID: 39799100, DOI: 10.1016/j.rbmo.2024.103944.Peer-Reviewed Original ResearchPlanned OCPlanned oocyte cryopreservationOocyte cryopreservationDecision Regret ScaleDecision Regret Scale scoresDecision regretCryopreserved oocytesDonor spermREDCap platformMultivariate modelEligibility criteriaReproductive plansProportion of respondentsDRS scoresDecreased numberWomenRegret ScaleOocytesCryopreservationScoresGroup
2019
Diminished ovarian reserve versus ovarian aging: overlaps and differences.
Ata B, Seyhan A, Seli E. Diminished ovarian reserve versus ovarian aging: overlaps and differences. Current Opinion In Obstetrics & Gynecology 2019, 31: 139-147. PMID: 30870184, DOI: 10.1097/gco.0000000000000536.Peer-Reviewed Original ResearchConceptsNormal ovarian reserveOvarian reservePregnancy lossOocyte qualityReproductive technology cyclesAge-matched womenDiminished ovarian reserveLow ovarian reserveFetal chromosomal abnormalitiesQuantitative declineFecundity of womenOvarian stimulationNatural conceptionOvarian agingPoor responseART treatmentAged womenYoung womenChromosomal abnormalitiesAvailable evidenceDecreased numberQualitative declineOocyte poolWomenBlastocyst development
2018
Impact of Cost Display on Ordering Patterns for Hospital Laboratory and Imaging Services
Silvestri MT, Xu X, Long T, Bongiovanni T, Bernstein SL, Chaudhry SI, Silvestri JI, Stolar M, Greene EJ, Dziura JD, Gross CP, Krumholz HM. Impact of Cost Display on Ordering Patterns for Hospital Laboratory and Imaging Services. Journal Of General Internal Medicine 2018, 33: 1268-1275. PMID: 29845468, PMCID: PMC6082197, DOI: 10.1007/s11606-018-4495-6.Peer-Reviewed Original ResearchConceptsDecreased oddsImaging ordersHealth care servicesBehalf of patientsKey ResultsDuringMain MeasuresOutcomesParticipantsAll patientsHospital encountersImaging testsObservation encountersCare servicesHealth servicesMedicare fee scheduleHealth systemImaging costsDecreased numberHospital laboratoriesLab ordersStudy periodHospital labPatients
2009
Placental Insufficiency Associated with Loss of Cited1 Causes Renal Medullary Dysplasia
Sparrow DB, Boyle SC, Sams RS, Mazuruk B, Zhang L, Moeckel GW, Dunwoodie SL, de Caestecker MP. Placental Insufficiency Associated with Loss of Cited1 Causes Renal Medullary Dysplasia. Journal Of The American Society Of Nephrology 2009, 20: 777-786. PMID: 19297558, PMCID: PMC2663829, DOI: 10.1681/asn.2008050547.Peer-Reviewed Original ResearchConceptsRenal medullary dysplasiaPlacental insufficiencyTissue oxygenationLower urinary tract obstructionUrinary tract obstructionCITED1 expressionIntrauterine growth retardationTract obstructionRenal functionMedullary growthRenal dysplasiaDysplasiaGrowth retardationRenal medullaMutant miceDecreased numberInsufficiencyEarly nephrogenesisNumber of studiesMiceGenetic lossOxygenationUreteric budCircumstantial evidenceInfants
2002
Inducible, reversible hair loss in transgenic mice
Chen J, Kelz MB, Zeng G, Steffen C, Shockett PE, Terwilliger G, Schatz DG, Nestler EJ. Inducible, reversible hair loss in transgenic mice. Transgenic Research 2002, 11: 241-247. PMID: 12113456, DOI: 10.1023/a:1015619604318.Peer-Reviewed Original ResearchConceptsTelogen effluviumInducible transgenic miceHair lossTransgenic miceReversible hair lossSkin pathologyHair loss phenotypeAnimal modelsMolecular abnormalitiesDecreased numberMiceHair folliclesAnagen phaseCommon typeEffluviumTelogen phasePresent findingsLoss phenotypeFolliclesPathologyMolecular mechanismsMorphological changesReporter luciferase geneLuciferase geneHigh levels
1998
Accuracy of CLOtest after Helicobacter pylori therapy
Laine L, Suchower L, Johnson E, Ronca P, Neil G. Accuracy of CLOtest after Helicobacter pylori therapy. Gastrointestinal Endoscopy 1998, 47: 250-253. PMID: 9540877, DOI: 10.1016/s0016-5107(98)70321-9.Peer-Reviewed Original ResearchConceptsHelicobacter pylori therapyPylori therapyOmeprazole/amoxicillinCompletion of therapyDouble-blind trialRapid urease testingMore effective therapiesEndoscopic biopsy testsOmeprazole therapyAdditional therapyMost patientsDual therapyUnsuccessful treatmentUrease testingEffective therapyPositive testPatientsH. pyloriTherapyCLOtestBiopsy testsDecreased numberWeeksNegative resultsAmoxicillin
1985
Delayed Pulmonary Maturation in the Fetus of the Streptozotocin-Diabetic Rat
Gewolb I, Rooney S, Barrett C, Ingleson L, Light D, Wilson C, Smith G, Gross I, Warshaw J. Delayed Pulmonary Maturation in the Fetus of the Streptozotocin-Diabetic Rat. Experimental Lung Research 1985, 8: 141-151. PMID: 4029093, DOI: 10.3109/01902148509057518.Peer-Reviewed Original ResearchConceptsStreptozotocin-diabetic ratsDiabetic groupPulmonary maturationDay 21Lung developmentDelayed pulmonary maturationAlveolar lining cellsEffects of hyperglycemiaFetal lung developmentDays of gestationObserved developmental delayType II cellsControl lungsMaturational delayCholinephosphate cytidylyltransferase activityIntravenous injectionRat gestationDiabetic fetusesLining cellsDay 22Day 20FetusesActivity of enzymesDevelopmental delayDecreased number
1975
In vitro granulocyte production in patients with Hodgkin's disease and lymphocytic, histiocytic, and mixed lymphomas.
Bull J, DeVita V, Carbone P. In vitro granulocyte production in patients with Hodgkin's disease and lymphocytic, histiocytic, and mixed lymphomas. Blood 1975, 45: 833-42. PMID: 1125431, DOI: 10.1182/blood.v45.6.833.bloodjournal456833.Peer-Reviewed Original ResearchConceptsHodgkin's diseaseMixed lymphomaUntreated patientsHistiocytic-lymphocytic lymphomasAdvanced Hodgkin's diseaseMOPP chemotherapyGranulocyte colony formationCombination chemotherapyMarrow culturesCFU-CIn vitro examinationLymphomaChemotherapyGranulocyte productionPatientsLong-term effectsAcute responseHodgkinColony formationDecreased numberDiseaseColony growthIn Vitro Granulocyte Production in Patients With Hodgkin’s Disease and Lymphocytic, Histiocytic, and Mixed Lymphomas
Bull J, DeVita V, Carbone P. In Vitro Granulocyte Production in Patients With Hodgkin’s Disease and Lymphocytic, Histiocytic, and Mixed Lymphomas. Blood 1975, 45: 833-842. DOI: 10.1182/blood.v45.6.833.833.Peer-Reviewed Original ResearchHodgkin's diseaseMixed lymphomaUntreated patientsHistiocytic-lymphocytic lymphomasAdvanced Hodgkin's diseaseMOPP chemotherapyGranulocyte colony formationCombination chemotherapyMarrow culturesCFU-CIn vitro examinationLymphomaChemotherapyGranulocyte productionPatientsLong-term effectsAcute responseHodgkinColony formationDecreased numberDiseaseColony growth
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