2004
Minimally invasive coronary artery bypass grafting versus stenting for patients with proximal left anterior descending coronary artery disease
Shirai K, Lansky AJ, Mehran R, Dangas GD, Costantini CO, Fahy M, Slack S, Mintz GS, Stone GW, Leon MB. Minimally invasive coronary artery bypass grafting versus stenting for patients with proximal left anterior descending coronary artery disease. The American Journal Of Cardiology 2004, 93: 959-962. PMID: 15081435, DOI: 10.1016/j.amjcard.2003.12.048.Peer-Reviewed Original ResearchConceptsCoronary artery bypassInvasive coronary artery bypassLAD stentingCoronary artery diseaseArtery bypassArtery diseaseClinical outcomesAnterior descending (LAD) coronary artery diseaseConventional coronary artery bypassHigher repeat revascularization ratesQ-wave myocardial infarctionHospital event ratesProximal LAD diseaseRepeat revascularization rateShorter hospital staySubgroup of patientsConventional balloon angioplastyIncidence of deathLong-term efficacyLAD revascularizationMIDCAB groupHospital stayLAD diseaseRevascularization ratesVessel revascularizationShort- and long-term results after multivessel stenting in diabetic patients
Moses J, Mehran R, Dangas G, Kobayashi Y, Lansky A, Mintz G, Aymong E, Fahy M, Stone GW, Leon MB. Short- and long-term results after multivessel stenting in diabetic patients. Journal Of The American College Of Cardiology 2004, 43: 1348-1354. PMID: 15093865, DOI: 10.1016/j.jacc.2003.04.004.Peer-Reviewed Original ResearchConceptsCoronary artery bypass graft surgeryNon-diabetic patientsHospital coronary artery bypass graft surgeryOne-year survivalDiabetic patientsMultivessel stentingOral agentsRevascularization ratesClinical outcomesProcedural successMyocardial infarctionTarget lesion revascularization rateArtery bypass graft surgeryHigh technical success rateDiabetes mellitus statusExcellent procedural successHospital cardiac deathSubsequent revascularization ratesBypass graft surgeryLesion revascularization rateNative coronary lesionsOne-year mortalityTechnical success rateConventional balloon angioplastyAcceptable clinical outcomes
2003
Acute and long-term outcomes of cutting balloon angioplasty followed by gamma brachytherapy for in-stent restenosis
Kobayashi Y, Mehran R, Mintz GS, Dangas G, Moussa I, Collins M, Brara P, Moussavian M, Lansky AJ, Stone GW, Leon MB, Moses JW, Teirstein PS. Acute and long-term outcomes of cutting balloon angioplasty followed by gamma brachytherapy for in-stent restenosis. The American Journal Of Cardiology 2003, 92: 1329-1331. PMID: 14636914, DOI: 10.1016/j.amjcard.2003.08.018.Peer-Reviewed Original Research
2002
New-Device Angioplasty in Women: Clinical Outcome and Predictors in a 7,372-Patient Registry
Lansky AJ, Mehran R, Dangas G, Desai K, Costantini-Ortiz C, Cristea E, New G, Negoita M, Stone GW, Leon MB. New-Device Angioplasty in Women: Clinical Outcome and Predictors in a 7,372-Patient Registry. Epidemiology 2002, 13: s46-s51. PMID: 12071484, DOI: 10.1097/00001648-200205001-00010.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsNew device angioplastyClinical outcomesFemale genderHospital mortalityLate mortalityIndependent predictorsMortality rateHospital major adverse cardiac eventsIschemic coronary artery diseaseLong-term clinical outcomesSaphenous vein graft lesionsMultivariable logistic regression analysisDevice-specific outcomesHospital cardiac mortalityLate clinical outcomesAdverse cardiac eventsComorbid risk factorsCongestive heart failureNative coronary arteriesOutcomes of womenVein graft lesionsCoronary artery diseaseReference vessel sizeConventional balloon angioplasty
1998
Final Results of the Balloon vs Optimal Atherectomy Trial (BOAT)
Baim D, Cutlip D, Sharma S, Ho K, Fortuna R, Schreiber T, Feldman R, Shani J, Senerchia C, Zhang Y, Lansky A, Popma J, Kuntz R. Final Results of the Balloon vs Optimal Atherectomy Trial (BOAT). Circulation 1998, 97: 322-331. PMID: 9468205, DOI: 10.1161/01.cir.97.4.322.Peer-Reviewed Original ResearchConceptsAngiographic restenosisBalloon angioplastyHigh short-term successPrespecified primary end pointLower angiographic restenosisNative vessel lesionsSingle de novoPrimary end pointTarget vessel failureTarget vessel revascularizationResidual diameter stenosisLate clinical eventsConventional balloon angioplastyCreatine kinase-MBLow residual stenosisSignificant reductionHospital complicationsResidual stenosisLesion successMajor complicationsAngiographic restudyDiameter stenosisVessel lesionsClinical eventsLong-term benefits
1997
Health after coronary stenting or balloon angioplasty: Results from the Stent Restenosis Study
Krumholz H, Cohen D, Williams C, Baim D, Brinker J, Cabin H, Heuser R, Hirshfeld J, Leon M, Moses J, Savage M, Cleman M. Health after coronary stenting or balloon angioplasty: Results from the Stent Restenosis Study. American Heart Journal 1997, 134: 337-344. PMID: 9327686, DOI: 10.1016/s0002-8703(97)70065-6.Peer-Reviewed Original ResearchConceptsStent Restenosis StudyCoronary stentingBalloon angioplastyRestenosis StudyDuke Activity Status IndexPalmaz-Schatz coronary stentingCanadian Cardiovascular Society classificationPalmaz-Schatz coronary stent implantationPercutaneous transluminal coronary angioplastyU.S. clinical sitesLong-term HRQoLForm Health SurveyHealth-related qualityMedical Outcomes StudyTransluminal coronary angioplastyCoronary stent implantationConventional balloon angioplastyDisease-specific measuresAngiographic restenosisConventional angioplastyIschemic eventsBodily painConsecutive patientsCoronary angioplastyCardiovascular perspectiveLocal urokinase delivery with the Channel balloon: Device safety, pharmacokinetics of intracoronary drug delivery, and efficacy of thrombolysis
Mitchel J, Barry J, Bow L, Alberghini T, Abbas S, McKay R. Local urokinase delivery with the Channel balloon: Device safety, pharmacokinetics of intracoronary drug delivery, and efficacy of thrombolysis. Catheterization And Cardiovascular Interventions 1997, 41: 254-260. PMID: 9213023, DOI: 10.1002/(sici)1097-0304(199707)41:3<254::aid-ccd5>3.0.co;2-5.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, Balloon, CoronaryAnimalsCell DivisionDrug Delivery SystemsEquipment DesignEquipment SafetyFeasibility StudiesFemaleFibrinolytic AgentsIliac ArteryMaleMuscle, Smooth, VascularProliferating Cell Nuclear AntigenSwineThrombolytic TherapyTreatment OutcomeTunica MediaUrokinase-Type Plasminogen ActivatorConceptsLocal urokinase deliveryConventional balloon angioplastyBalloon angioplastyDrug infusionDrug depositionPorcine modelLocal drug delivery catheterLocal deliveryDrug delivery catheterEfficacy of thrombolysisComparative histologic studyCatheter infusionBalloon useVessel traumaCoronary arteryLocal infusionThrombolytic techniquesIntracoronary useHistologic changesBalloon inflationIntramural depositionHistologic studyArtery ratioCoronary vesselsAnesthetized swine
1996
Angiographic and Clinical Outcome after Cutting Balloon Angioplasty.
Popma J, Lansky A, Purkayastha D, Hall L, Bonan R. Angiographic and Clinical Outcome after Cutting Balloon Angioplasty. Journal Of Invasive Cardiology 1996, 8 Suppl A: 12a-19a. PMID: 10785760.Peer-Reviewed Original ResearchBalloon angioplastyConventional balloon angioplastyResidual stenosisClinical outcomesBalloon useDiameter stenosisArtery ratioNon-complex coronary artery diseaseComplex coronary artery diseaseCutting Balloon AngioplastyReference artery sizeCoronary artery diseaseMinimal lumen diameterCore laboratory analysisPrevention of restenosisAngiographic core laboratory analysisNew device angioplastyHospital complicationsOstial locationAngiographic successArtery diseaseConsecutive patientsArtery sizeSignificant inverse relationshipMorphologic findings
1995
In-hospital and one-year economic outcomes after coronary stenting or balloon angioplasty. Results from a randomized clinical trial. Stent Restenosis Study Investigators.
Cohen D, Krumholz H, Sukin C, Ho K, Siegrist R, Cleman M, Heuser R, Brinker J, Moses J, Savage M, Detre K, Leon M, Baim D. In-hospital and one-year economic outcomes after coronary stenting or balloon angioplasty. Results from a randomized clinical trial. Stent Restenosis Study Investigators. Circulation 1995, 92: 2480-7. PMID: 7586348, DOI: 10.1161/01.cir.92.9.2480.Peer-Reviewed Original ResearchConceptsMedical care costsInitial hospital costsCoronary stentingVascular complicationsConventional angioplastyBalloon angioplastyCare costsInitial hospitalizationInitial stentingHospital costsPalmaz-Schatz coronary stent implantationCatheterization laboratory costsElective coronary stentingPatient's initial hospitalizationSingle coronary lesionsSubsequent hospital visitsSubsequent revascularization proceduresSymptomatic coronary diseaseCoronary stent implantationConventional balloon angioplastyRandomized clinical trialsLength of stayDetailed resource utilizationAngiographic restenosisRepeat revascularizationLength of hospital stay and complications after percutaneous transluminal coronary angioplasty. Clinical and procedural predictors. Heparin Registry Investigators.
Wolfe M, Roubin G, Schweiger M, Isner J, Ferguson J, Cannon A, Cleman M, Cabin H, Leya F, Bonan R, Strony J, Adelman B, Bittl J. Length of hospital stay and complications after percutaneous transluminal coronary angioplasty. Clinical and procedural predictors. Heparin Registry Investigators. Circulation 1995, 92: 311-9. PMID: 7634443, DOI: 10.1161/01.cir.92.3.311.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal coronary angioplastyLength of stayMultivessel coronary artery diseasePTCA complicationsCoronary artery diseaseTransluminal coronary angioplastyHospital stayUnstable anginaBaseline variablesAdvanced ageComplex lesionsArtery diseaseCoronary angioplastyLesion complexityNon-Q-wave myocardial infarctionIndividual baseline variablesBaseline risk factorsClinical risk scoreEmergency bypass surgeryProlonged hospital staySelection of patientsAbrupt vessel closureConventional balloon angioplastyAccess of patientsStrongest predictorEnhanced intracoronary thrombolysis with urokinase using a novel, local drug delivery system. In vitro, in vivo, and clinical studies.
Mitchel J, Fram D, Palme D, Foster R, Hirst J, Azrin M, Bow L, Eldin A, Waters D, McKay R. Enhanced intracoronary thrombolysis with urokinase using a novel, local drug delivery system. In vitro, in vivo, and clinical studies. Circulation 1995, 91: 785-93. PMID: 7828307, DOI: 10.1161/01.cir.91.3.785.Peer-Reviewed Original ResearchConceptsDispatch catheterLocal infusionEnd-hole catheterU urokinaseCatheter infusionIntracoronary thrombusAngioplasty siteUrokinase administrationLocal drug delivery systemIntracoronary thrombolysisUrokinase infusionBalloon angioplastySystemic bolusIntramural depositionNew local drug delivery systemDistal coronary flowLocal urokinase deliveryLocal urokinase infusionThrombus-containing stenosesConventional balloon angioplastyInfusion of urokinaseInfusion of salinePorcine coronary arteriesSystemic fibrinolytic stateCardiac catheterization laboratory
1994
Inhibition of platelet deposition and lysis of intracoronary thrombus during balloon angioplasty using urokinase-coated hydrogel balloons.
Mitchel J, Azrin M, Fram D, Hong M, Wong S, Barry J, Bow L, Curley T, Kiernan F, Waters D. Inhibition of platelet deposition and lysis of intracoronary thrombus during balloon angioplasty using urokinase-coated hydrogel balloons. Circulation 1994, 90: 1979-1988. PMID: 7923688, DOI: 10.1161/01.cir.90.4.1979.Peer-Reviewed Original ResearchConceptsLocal urokinase deliveryVivo balloon angioplastyIntracoronary thrombusBalloon angioplastyPlatelet depositionThrombotic closureDistal embolizationAngioplasty siteAbrupt closureArterial wallHydrogel balloonContralateral control arteriesContralateral control vesselsIntramural drug deliveryVivo studiesConventional balloon angioplastyNew Zealand rabbitsU urokinaseConventional angioplastyBalloon dilatationClinical efficacyReflow phenomenonIliac arteryBlood exposureControl arteries
1993
Fate of lesion-related side branches after coronary artery stenting
Fischman D, Savage M, Leon M, Schatz R, Ellis S, Cleman M, Hirshfeld J, Teirstein P, Bailey S, Walker C, Goldberg S. Fate of lesion-related side branches after coronary artery stenting. Journal Of The American College Of Cardiology 1993, 22: 1641-1646. PMID: 8227832, DOI: 10.1016/0735-1097(93)90589-s.Peer-Reviewed Original ResearchConceptsSide branch occlusionStandard balloon angioplastyBalloon angioplastyBranch occlusionOstial stenosisCoronary arteryStent placementAcute side branch occlusionPalmaz-Schatz stent placementSide branchesImportant potential complicationConventional balloon angioplastySerial coronary angiographyLong-term patencySide branch ostiumPossible adverse effectsConventional angioplastyCoronary angiographyCoronary stentingMechanical obstructionPotential complicationsOstial diseaseAngioplastyPatencyCoronary stents
1991
Effect of intracoronary stenting on intimal dissection after balloon angioplasty: Results of quantitative and qualitative coronary analysis
Fischman D, Savage M, Leon M, Schatz R, Ellis S, Cleman M, Teirstein P, Walker C, Bailey S, Hirshfeld J, Goldberg S. Effect of intracoronary stenting on intimal dissection after balloon angioplasty: Results of quantitative and qualitative coronary analysis. Journal Of The American College Of Cardiology 1991, 18: 1445-1451. PMID: 1939944, DOI: 10.1016/0735-1097(91)90673-w.Peer-Reviewed Original ResearchConceptsResidual luminal stenosisIntimal dissectionBalloon angioplastyIntracoronary stentingAngiographic appearanceStent implantationLuminal stenosisGrade 0Simple dissectionMean diameter stenosisComplex dissectionConventional balloon angioplastyPalmaz-Schatz stentsQuantitative coronary analysisConventional angioplastyConsecutive patientsCoronary angiographyIntimal disruptionDiameter stenosisDissection gradeAngioplastyGrade 2Grade 1StenosisDissection
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